Early-life antibiotic treatment enhances the pathogenicity of CD4+ T cells during intestinal inflammation

Journal of Leukocyte Biology

Volumn 101, Issue 4, 2017, Pages 893-900

  Scheer, Sebastian ^a,b   Medina, Tiago S ^c   Murison, Alex ^c   Taves, Matthew D ^a   Antignano, Frann ^a   Chenery, Alistair ^a   Soma, Kiran K ^a   Perona Wright, Georgia ^a   Lupien, Mathieu ^c,d,f   Arrowsmith, Cheryl H ^c,d,e   De Carvalho, Daniel D ^c   Zaph, Colby ^a,b  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b MONASH UNIVERSITY   (Australia)

^c PRINCESS MARGARET HOSPITAL   (Canada)

^d UNIVERSITY OF TORONTO   (Canada)

^e UNIVERSITY OF TORONTO   (Canada)

^f ONTARIO INSTITUTE FOR CANCER RESEARCH   (Canada)

Author keywords

Antibiotics; Corticosterone; Inflammatory bowel disease; Mouse model; Stress

Indexed keywords

CORTICOSTERONE; ANTIINFECTIVE AGENT; CYTOKINE; LYMPHOCYTE ANTIGEN RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBIOTIC THERAPY; ARTICLE; CD4+ T LYMPHOCYTE; CELL TRANSFER; CELLULAR STRESS RESPONSE; CONTROLLED STUDY; CORTICOSTERONE BLOOD LEVEL; DISEASE SEVERITY; ENTERITIS; GENE EXPRESSION; INTESTINE FLORA; MOUSE; NONHUMAN; PATHOGENICITY; PRIORITY JOURNAL; ANIMAL; ANIMAL HOUSING; BLOOD; C57BL MOUSE; DRUG EFFECTS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENETICS; GENOME; IMMUNOLOGY; INFLAMMATION; INFLAMMATORY BOWEL DISEASES; INTESTINE MUCOSA; METABOLISM; PATHOLOGY;

ANIMALS; ANTI-BACTERIAL AGENTS; CD4-POSITIVE T-LYMPHOCYTES; CORTICOSTERONE; CYTOKINES; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENOME; HOUSING, ANIMAL; INFLAMMATION; INFLAMMATORY BOWEL DISEASES; INTESTINAL MUCOSA; MICE, INBRED C57BL; RECEPTORS, ANTIGEN, T-CELL;

EID: 85017311250     PISSN: 07415400     EISSN: 19383673     Source Type: Journal    
DOI: 10.1189/jlb.3MA0716-334RR     Document Type: Article

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