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Volumn 64, Issue 10, 2017, Pages

Molecular characterization of acute lymphoblastic leukemia with high CRLF2 gene expression in childhood

Author keywords

acute lymphoblastic leukemia; CRLF2; IGH CRLF2; P2RY8 CRLF2; prognosis

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR 2A; CYCLIN DEPENDENT KINASE INHIBITOR 2B; JANUS KINASE 2; MESSENGER RNA; PROTEIN; PROTEIN BTG1; PROTEIN CRLF2; PROTEIN IKZF1; PROTEIN RB1; TRANSCRIPTION FACTOR ETV6; TRANSCRIPTION FACTOR PAX5; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; ASPARAGINASE; CRLF2 PROTEIN, HUMAN; CYTOKINE RECEPTOR; DAUNORUBICIN; IKAROS TRANSCRIPTION FACTOR; IKZF1 PROTEIN, HUMAN; ONCOPROTEIN; P2RY8 PROTEIN, HUMAN; PAX5 PROTEIN, HUMAN; PREDNISONE; PURINERGIC P2Y RECEPTOR; VINCRISTINE;

EID: 85017147206     PISSN: 15455009     EISSN: 15455017     Source Type: Journal    
DOI: 10.1002/pbc.26539     Document Type: Article
Times cited : (30)

References (22)
  • 1
    • 77951441599 scopus 로고    scopus 로고
    • Molecular response to treatment redefines all prognostic factors in children and adolescents with B-cell precursor acute lymphoblastic leukemia: results in 3184 patients of the AIEOP-BFM ALL 2000 study
    • Conter V, Bartram CR, Valsecchi MG, et al. Molecular response to treatment redefines all prognostic factors in children and adolescents with B-cell precursor acute lymphoblastic leukemia: results in 3184 patients of the AIEOP-BFM ALL 2000 study. Blood. 2010;115(16):3206–3214.
    • (2010) Blood , vol.115 , Issue.16 , pp. 3206-3214
    • Conter, V.1    Bartram, C.R.2    Valsecchi, M.G.3
  • 2
    • 42349085052 scopus 로고    scopus 로고
    • Minimal residual disease-directed risk stratification using real-time quantitative PCR analysis of immunoglobulin and T-cell receptor gene rearrangements in the international multicenter trial AIEOP-BFM ALL 2000 for childhood acute lymphoblastic leukemia
    • Flohr T, Schrauder A, Cazzaniga G, et al. Minimal residual disease-directed risk stratification using real-time quantitative PCR analysis of immunoglobulin and T-cell receptor gene rearrangements in the international multicenter trial AIEOP-BFM ALL 2000 for childhood acute lymphoblastic leukemia. Leukemia. 2008;22(4):771–782.
    • (2008) Leukemia , vol.22 , Issue.4 , pp. 771-782
    • Flohr, T.1    Schrauder, A.2    Cazzaniga, G.3
  • 3
    • 70350680415 scopus 로고    scopus 로고
    • Rearrangement of CRLF2 in B-progenitor- and Down syndrome-associated acute lymphoblastic leukemia
    • Mullighan CG, Collins-Underwood JR, Phillips LA, et al. Rearrangement of CRLF2 in B-progenitor- and Down syndrome-associated acute lymphoblastic leukemia. Nat Genet. 2009;41(11):1243–1246.
    • (2009) Nat Genet , vol.41 , Issue.11 , pp. 1243-1246
    • Mullighan, C.G.1    Collins-Underwood, J.R.2    Phillips, L.A.3
  • 4
    • 70350519430 scopus 로고    scopus 로고
    • Deregulated expression of cytokine receptor gene, CRLF2, is involved in lymphoid transformation in B-cell precursor acute lymphoblastic leukemia
    • Russell LJ, Capasso M, Vater I, et al. Deregulated expression of cytokine receptor gene, CRLF2, is involved in lymphoid transformation in B-cell precursor acute lymphoblastic leukemia. Blood. 2009;114(13):2688–2698.
    • (2009) Blood , vol.114 , Issue.13 , pp. 2688-2698
    • Russell, L.J.1    Capasso, M.2    Vater, I.3
  • 5
    • 84867404417 scopus 로고    scopus 로고
    • Poor prognosis for P2RY8-CRLF2 fusion but not for CRLF2 over-expression in children with intermediate risk B-cell precursor acute lymphoblastic leukemia
    • Palmi C, Vendramini E, Silvestri D, et al. Poor prognosis for P2RY8-CRLF2 fusion but not for CRLF2 over-expression in children with intermediate risk B-cell precursor acute lymphoblastic leukemia. Leukemia. 2012;26(10):2245–2253.
    • (2012) Leukemia , vol.26 , Issue.10 , pp. 2245-2253
    • Palmi, C.1    Vendramini, E.2    Silvestri, D.3
  • 6
    • 84871481072 scopus 로고    scopus 로고
    • Small sizes and indolent evolutionary dynamics challenge the potential role of P2RY8-CRLF2-harboring clones as main relapse-driving force in childhood ALL
    • Morak M, Attarbaschi A, Fischer S, et al. Small sizes and indolent evolutionary dynamics challenge the potential role of P2RY8-CRLF2-harboring clones as main relapse-driving force in childhood ALL. Blood. 2012;120(26):5134–5142.
    • (2012) Blood , vol.120 , Issue.26 , pp. 5134-5142
    • Morak, M.1    Attarbaschi, A.2    Fischer, S.3
  • 7
    • 77954500629 scopus 로고    scopus 로고
    • Presence of the P2RY8-CRLF2 rearrangement is associated with a poor prognosis in non-high-risk precursor B-cell acute lymphoblastic leukemia in children treated according to the ALL-BFM 2000 protocol
    • Cario G, Zimmermann M, Romey R, et al. Presence of the P2RY8-CRLF2 rearrangement is associated with a poor prognosis in non-high-risk precursor B-cell acute lymphoblastic leukemia in children treated according to the ALL-BFM 2000 protocol. Blood. 2010;115(26):5393–5397.
    • (2010) Blood , vol.115 , Issue.26 , pp. 5393-5397
    • Cario, G.1    Zimmermann, M.2    Romey, R.3
  • 8
    • 84905722742 scopus 로고    scopus 로고
    • An overall characterization of pediatric acute lymphoblastic leukemia with 2 overexpression
    • Yano M, Imamura T, Asai D, et al. An overall characterization of pediatric acute lymphoblastic leukemia with 2 overexpression. Genes Chromosomes Cancer. 2014;53(10):815–823.
    • (2014) Genes Chromosomes Cancer , vol.53 , Issue.10 , pp. 815-823
    • Yano, M.1    Imamura, T.2    Asai, D.3
  • 9
    • 84859820034 scopus 로고    scopus 로고
    • Outcome modeling with CRLF2, IKZF1, JAK, and minimal residual disease in pediatric acute lymphoblastic leukemia: a Children's Oncology Group study
    • Chen IM, Harvey RC, Mullighan CG, et al. Outcome modeling with CRLF2, IKZF1, JAK, and minimal residual disease in pediatric acute lymphoblastic leukemia: a Children's Oncology Group study. Blood. 2012;119(15):3512–3522.
    • (2012) Blood , vol.119 , Issue.15 , pp. 3512-3522
    • Chen, I.M.1    Harvey, R.C.2    Mullighan, C.G.3
  • 10
    • 84991390931 scopus 로고    scopus 로고
    • CRLF2 over-expression is a poor prognostic marker in children with high risk T-cell acute lymphoblastic leukemia
    • Palmi C, Savino AM, Silvestri D, et al. CRLF2 over-expression is a poor prognostic marker in children with high risk T-cell acute lymphoblastic leukemia. Oncotarget. 2016;7(37):59260–59272.
    • (2016) Oncotarget , vol.7 , Issue.37 , pp. 59260-59272
    • Palmi, C.1    Savino, A.M.2    Silvestri, D.3
  • 11
    • 77649214639 scopus 로고    scopus 로고
    • Down syndrome acute lymphoblastic leukemia, a highly heterogeneous disease in which aberrant expression of CRLF2 is associated with mutated JAK2: a report from the International BFM Study Group
    • Hertzberg L, Vendramini E, Ganmore I, et al. Down syndrome acute lymphoblastic leukemia, a highly heterogeneous disease in which aberrant expression of CRLF2 is associated with mutated JAK2: a report from the International BFM Study Group. Blood. 2010;115(5):1006–1017.
    • (2010) Blood , vol.115 , Issue.5 , pp. 1006-1017
    • Hertzberg, L.1    Vendramini, E.2    Ganmore, I.3
  • 12
    • 0037139417 scopus 로고    scopus 로고
    • Interphase FISH assays for the detection of translocations with breakpoints in immunoglobulin light chain loci
    • Martin-Subero JI, Harder L, Gesk S, et al. Interphase FISH assays for the detection of translocations with breakpoints in immunoglobulin light chain loci. Int J Cancer. 2002;98(3):470–474.
    • (2002) Int J Cancer , vol.98 , Issue.3 , pp. 470-474
    • Martin-Subero, J.I.1    Harder, L.2    Gesk, S.3
  • 13
    • 33744516644 scopus 로고    scopus 로고
    • FISH analysis for the detection of lymphoma-associated chromosomal abnormalities in routine paraffin-embedded tissue
    • Ventura RA, Martin-Subero JI, Jones M, et al. FISH analysis for the detection of lymphoma-associated chromosomal abnormalities in routine paraffin-embedded tissue. J Mol Diagn. 2006;8(2):141–151.
    • (2006) J Mol Diagn , vol.8 , Issue.2 , pp. 141-151
    • Ventura, R.A.1    Martin-Subero, J.I.2    Jones, M.3
  • 14
    • 0002322469 scopus 로고
    • On a test of whether one of 2 random variables is stochastically larger than the other
    • Mann HB, Whitney DR. On a test of whether one of 2 random variables is stochastically larger than the other. Ann Math Stat. 1947;18(1):50–60.
    • (1947) Ann Math Stat , vol.18 , Issue.1 , pp. 50-60
    • Mann, H.B.1    Whitney, D.R.2
  • 15
    • 85028012397 scopus 로고    scopus 로고
    • CRLF2 over-expression is a poor prognostic marker in children with high risk T-cell acute lymphoblastic leukemia
    • Palmi C, Silvestri D, Bronzini I, et al. CRLF2 over-expression is a poor prognostic marker in children with high risk T-cell acute lymphoblastic leukemia. Blood. 2014;124(21).
    • (2014) Blood , vol.124 , Issue.21
    • Palmi, C.1    Silvestri, D.2    Bronzini, I.3
  • 16
    • 76749102418 scopus 로고    scopus 로고
    • Long-term results of five consecutive trials in childhood acute lymphoblastic leukemia performed by the ALL-BFM study group from 1981 to 2000
    • Moricke A, Zimmermann M, Reiter A, et al. Long-term results of five consecutive trials in childhood acute lymphoblastic leukemia performed by the ALL-BFM study group from 1981 to 2000. Leukemia. 2010;24(2):265–284.
    • (2010) Leukemia , vol.24 , Issue.2 , pp. 265-284
    • Moricke, A.1    Zimmermann, M.2    Reiter, A.3
  • 17
    • 77956956123 scopus 로고    scopus 로고
    • t(X;14)(p22;q32)/t(Y;14)(p11;q32) CRLF2-IGH translocations from human B-lineage ALLs involve CpG-type breaks at CRLF2, but CRLF2/P2RY8 intrachromosomal deletions do not
    • Tsai AG, Yoda A, Weinstock DM, Lieber MR. t(X;14)(p22;q32)/t(Y;14)(p11;q32) CRLF2-IGH translocations from human B-lineage ALLs involve CpG-type breaks at CRLF2, but CRLF2/P2RY8 intrachromosomal deletions do not. Blood. 2010;116(11):1993–1994.
    • (2010) Blood , vol.116 , Issue.11 , pp. 1993-1994
    • Tsai, A.G.1    Yoda, A.2    Weinstock, D.M.3    Lieber, M.R.4
  • 18
    • 57349185631 scopus 로고    scopus 로고
    • Human chromosomal translocations at CpG sites and a theoretical basis for their lineage and stage specificity
    • Tsai AG, Lu H, Raghavan SC, Muschen M, Hsieh CL, Lieber MR. Human chromosomal translocations at CpG sites and a theoretical basis for their lineage and stage specificity. Cell. 2008;135(6):1130–1142.
    • (2008) Cell , vol.135 , Issue.6 , pp. 1130-1142
    • Tsai, A.G.1    Lu, H.2    Raghavan, S.C.3    Muschen, M.4    Hsieh, C.L.5    Lieber, M.R.6
  • 19
    • 43049139905 scopus 로고    scopus 로고
    • BCR-ABL1 lymphoblastic leukaemia is characterized by the deletion of Ikaros
    • Mullighan CG, Miller CB, Radtke I, et al. BCR-ABL1 lymphoblastic leukaemia is characterized by the deletion of Ikaros. Nature. 2008;453(7191):110–114.
    • (2008) Nature , vol.453 , Issue.7191 , pp. 110-114
    • Mullighan, C.G.1    Miller, C.B.2    Radtke, I.3
  • 20
    • 0037195805 scopus 로고    scopus 로고
    • Prevalent involvement of illegitimate V(D)J recombination in chromosome 9p21 deletions in lymphoid leukemia
    • Kitagawa Y, Inoue K, Sasaki S, et al. Prevalent involvement of illegitimate V(D)J recombination in chromosome 9p21 deletions in lymphoid leukemia. J Biol Chem. 2002;277(48):46289–46297.
    • (2002) J Biol Chem , vol.277 , Issue.48 , pp. 46289-46297
    • Kitagawa, Y.1    Inoue, K.2    Sasaki, S.3
  • 21
    • 84859193076 scopus 로고    scopus 로고
    • The origin and nature of tightly clustered BTG1 deletions in precursor B-cell acute lymphoblastic leukemia support a model of multiclonal evolution
    • Waanders E, Scheijen B, van der Meer LT, et al. The origin and nature of tightly clustered BTG1 deletions in precursor B-cell acute lymphoblastic leukemia support a model of multiclonal evolution. PLoS Genet. 2012;8(2):e1002533.
    • (2012) PLoS Genet , vol.8 , Issue.2
    • Waanders, E.1    Scheijen, B.2    van der Meer, L.T.3
  • 22
    • 84856147587 scopus 로고    scopus 로고
    • Beyond the 2008 World Health Organization classification: the role of the hematopathology laboratory in the diagnosis and management of acute lymphoblastic leukemia
    • McGregor S, McNeer J, Gurbuxani S. Beyond the 2008 World Health Organization classification: the role of the hematopathology laboratory in the diagnosis and management of acute lymphoblastic leukemia. Semin Diagn Pathol. 2012;29(1):2–11.
    • (2012) Semin Diagn Pathol , vol.29 , Issue.1 , pp. 2-11
    • McGregor, S.1    McNeer, J.2    Gurbuxani, S.3


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