Prophylactic Indomethacin Revisited

Journal of Pediatrics

Volumn 186, Issue , 2017, Pages 11-14.e1

  Reese, Jeff ^a   Shelton, Elaine L ^b   Slaughter, James C ^c   McNamara, Patrick J ^d  

^a Department of Cell and Developmental Biology ^*  (United States)

^b MONROE CARELL JR CHILDREN S HOSPITAL AT VANDERBILT   (United States)

^c VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d HOSPITAL FOR SICK CHILDREN   (Canada)

Author keywords

bronchopulmonary dysplasia; ductus arteriosus; indomethacin; prophylaxis

Indexed keywords

INDOMETACIN;

CLINICAL PRACTICE; EDITORIAL; HUMAN; MORTALITY RATE; PATENT DUCTUS ARTERIOSUS; PRIORITY JOURNAL; PROPHYLAXIS; TREATMENT INDICATION; TREATMENT OUTCOME; INFANT; LUNG DYSPLASIA; NEWBORN; PREMATURITY; RISK;

BRONCHOPULMONARY DYSPLASIA; HUMANS; INDOMETHACIN; INFANT; INFANT, EXTREMELY PREMATURE; INFANT, NEWBORN; RISK;

EID: 85017130284     PISSN: 00223476     EISSN: 10976833     Source Type: Journal    
DOI: 10.1016/j.jpeds.2017.03.036     Document Type: Editorial

References (48)

1. Lees, M.H., Commentary: patent ductus arteriosus in premature infants—a diagnostic and therapeutic dilemma. J Pediatr 86 (1975), 132–134.
2. Evans, N., Preterm patent ductus arteriosus: a continuing conundrum for the neonatologist?. Semin Fetal Neonatal Med 20 (2015), 272–277.
3. Alexi-Meskishvili, V.V., Bottcher, W., The first closure of the persistent ductus arteriosus. Ann Thorac Surg 90 (2010), 349–356.
4. Starling, M.B., Elliott, R.B., The effects of prostaglandins, prostaglandin inhibitors, and oxygen on the closure of the ductus arteriosus, pulmonary arteries and umbilical vessels in vitro. Prostaglandins 8 (1974), 187–203.
5. Sharpe, G.L., Thalme, B., Larsson, K.S., Studies on closure of the ductus arteriosus. XI. Ductal closure in utero by a prostaglandin synthetase inhibitor. Prostaglandins 8 (1974), 363–368.
6. Coceani, F., Olley, P.M., Bodach, E., Lamb ductus arteriosus: effect of prostaglandin synthesis inhibitors on the muscle tone and the response to prostaglandin E2. Prostaglandins 9 (1975), 299–308.
7. Elliott, R.B., Starling, M.B., Neutze, J.M., Medical manipulation of the ductus arteriosus. Lancet 1 (1975), 140–142.
8. Friedman, W.F., Hirschklau, M.J., Printz, M.P., Pitlick, P.T., Kirkpatrick, S.E., Pharmacologic closure of patent ductus arteriosus in the premature infant. N Engl J Med 295 (1976), 526–529.
9. Heymann, M.A., Rudolph, A.M., Silverman, N.H., Closure of the ductus arteriosus in premature infants by inhibition of prostaglandin synthesis. N Engl J Med 295 (1976), 530–533.
10. Knight, D.B., The treatment of patent ductus arteriosus in preterm infants. A review and overview of randomized trials. Semin Neonatol 6 (2001), 63–73.
11. Fanos, V., Pusceddu, M., Dessi, A., Marcialis, M.A., Should we definitively abandon prophylaxis for patent ductus arteriosus in preterm new-borns?. Clinics 66 (2011), 2141–2149.
12. Clyman, R.I., Couto, J., Murphy, G.M., Patent ductus arteriosus: are current neonatal treatment options better or worse than no treatment at all?. Semin Perinatol 36 (2012), 123–129.
13. Merritt, T.A., Harris, J.P., Roghmann, K., Wood, B., Campanella, V., Alexson, C., et al. Early closure of the patent ductus arteriosus in very low-birth-weight infants: a controlled trial. J Pediatr 99 (1981), 281–286.
14. Kaapa, P., Lanning, P., Koivisto, M., Early closure of patent ductus arteriosus with indomethacin in preterm infants with idiopathic respiratory distress syndrome. Acta Paediatr Scand 72 (1983), 179–184.
15. Mahony, L., Carnero, V., Brett, C., Heymann, M.A., Clyman, R.I., Prophylactic indomethacin therapy for patent ductus arteriosus in very-low-birth-weight infants. N Engl J Med 306 (1982), 506–510.
16. Burnard, E.D., Thomas, D.B., Grattan-Smith, P., Early indomethacin in patent ductus of the very small premature. Aust Paediatr J 18 (1982), 28–31.
17. Fowlie, P.W., Davis, P.G., McGuire, W., Prophylactic intravenous indomethacin for preventing mortality and morbidity in preterm infants. Cochrane Database Syst Rev(7), 2010 CD000174.
18. Ment, L.R., Stewart, W.B., Scott, D.T., Duncan, C.C., Beagle puppy model of intraventricular hemorrhage: randomized indomethacin prevention trial. Neurology 33 (1983), 179–184.
19. Ment, L.R., Duncan, C.C., Ehrenkranz, R.A., Kleinman, C.S., Pitt, B.R., Taylor, K.J., et al. Randomized indomethacin trial for prevention of intraventricular hemorrhage in very low birth weight infants. J Pediatr 107 (1985), 937–943.
20. Ment, L.R., Duncan, C.C., Ehrenkranz, R.A., Kleinman, C.S., Taylor, K.J., Scott, D.T., et al. Randomized low-dose indomethacin trial for prevention of intraventricular hemorrhage in very low birth weight neonates. J Pediatr 112 (1988), 948–955.
21. Mahony, L., Caldwell, R.L., Girod, D.A., Hurwitz, R.A., Jansen, R.D., Lemons, J.A., et al. Indomethacin therapy on the first day of life in infants with very low birth weight. J Pediatr 106 (1985), 801–805.
22. Thibeault, D.W., Emmanouilides, G.C., Nelson, R.J., Lachman, R.S., Rosengart, R.M., Oh, W., Patent ductus arteriosus complicating the respiratory distress syndrome in preterm infants. J Pediatr 86 (1975), 120–126.
23. McGrath, R.L., McGuinness, G.A., Way, G.L., Wolfe, R.R., Nora, J.J., Simmons, M.A., The silent ductus arteriosus. J Pediatr 93 (1978), 110–113.
24. Clyman, R.I., Saha, S., Jobe, A., Oh, W., Indomethacin prophylaxis for preterm infants: the impact of 2 multicentered randomized controlled trials on clinical practice. J Pediatr 150 (2007), 46–50 e2.
25. Bandstra, E.S., Montalvo, B.M., Goldberg, R.N., Pacheco, I., Ferrer, P.L., Flynn, J., et al. Prophylactic indomethacin for prevention of intraventricular hemorrhage in premature infants. Pediatrics 82 (1988), 533–542.
26. Bada, H.S., Green, R.S., Pourcyrous, M., Leffler, C.W., Korones, S.B., Magill, H.L., et al. Indomethacin reduces the risks of severe intraventricular hemorrhage. J Pediatr 115 (1989), 631–637.
27. Ment, L.R., Oh, W., Ehrenkranz, R.A., Philip, A.G., Vohr, B., Allan, W., et al. Low-dose indomethacin and prevention of intraventricular hemorrhage: a multicenter randomized trial. Pediatrics 93 (1994), 543–550.
28. Ment, L.R., Oh, W., Ehrenkranz, R.A., Phillip, A.G., Vohr, B., Allan, W., et al. Low-dose indomethacin therapy and extension of intraventricular hemorrhage: a multicenter randomized trial. J Pediatr 124 (1994), 951–955.
29. Gersony, W.M., Peckham, G.J., Ellison, R.C., Miettinen, O.S., Nadas, A.S., Effects of indomethacin in premature infants with patent ductus arteriosus: results of a national collaborative study. J Pediatr 102 (1983), 895–906.
30. Hammerman, C., Strates, E., Valaitis, S., The silent ductus: its precursors and its aftermath. Pediatr Cardiol 7 (1986), 121–127.
31. Schmidt, B., Davis, P., Moddemann, D., Ohlsson, A., Roberts, R.S., Saigal, S., et al. Long-term effects of indomethacin prophylaxis in extremely-low-birth-weight infants. N Engl J Med 344 (2001), 1966–1972.
32. Laughon, M., Bose, C., Clark, R., Treatment strategies to prevent or close a patent ductus arteriosus in preterm infants and outcomes. J Perinatol 27 (2007), 164–170.
33. Schmidt, B., Roberts, R.S., Fanaroff, A., Davis, P., Kirpalani, H.M., Nwaesei, C., et al. Indomethacin prophylaxis, patent ductus arteriosus, and the risk of bronchopulmonary dysplasia: further analyses from the Trial of Indomethacin Prophylaxis in Preterms (TIPP). J Pediatr 148 (2006), 730–734.
34. Laughon, M.M., Simmons, M.A., Bose, C.L., Patency of the ductus arteriosus in the premature infant: is it pathologic? Should it be treated?. Curr Opin Pediatr 16 (2004), 146–151.
35. Benitz, W.E., Treatment of persistent patent ductus arteriosus in preterm infants: time to accept the null hypothesis?. J Perinatol 30 (2010), 241–252.
36. Jensen, E.A., Dysart, K.C., Gantz, M.G., Carper, B., Higgins, R.D., Keszler, M., et al. Association between use of prophylactic indomethacin and the risk for bronchopulmonary dysplasia in extremely preterm infants. J Pediatr 186 (2017), 34–40.
37. Slaughter, J.L., Reagan, P.B., Bapat, R.V., Newman, T.B., Klebanoff, M.A., Nonsteroidal anti-inflammatory administration and patent ductus arteriosus ligation, a survey of practice preferences at US children's hospitals. Eur J Pediatr 175 (2016), 775–783.
38. Brissaud, O., Guichoux, J., Patent ductus arteriosus in the preterm infant: a survey of clinical practices in French neonatal intensive care units. Pediatr Cardiol 32 (2011), 607–614.
39. Rolnitsky, A., Lee, S.K., Piedbouf, B., Harrison, A., Shah, P.S., Canadian Neonatal Network. Prophylactic interventions in neonatology: how do they fare in real life?. Am J Perinatol 32 (2015), 1098–1104.
40. Guimaraes, H., Rocha, G., Tome, T., Anatolitou, F., Sarafidis, K., Fanos, V., Non-steroid anti-inflammatory drugs in the treatment of patent ductus arteriosus in European newborns. J Matern Fetal Neonatal Med 22:suppl 3 (2009), 77–80.
41. Irmesi, R., Marcialis, M.A., Anker, J.V., Fanos, V., Non-steroidal anti-inflammatory drugs (NSAIDs) in the management of patent ductus arteriosus (PDA) in preterm infants and variations in attitude in clinical practice: a flight around the world. Curr Med Chem 21 (2014), 3132–3152.
42. Lee, J.A., Kim, M.J., Oh, S., Choi, B.M., Current status of therapeutic strategies for patent ductus arteriosus in very-low-birth-weight infants in Korea. J Korean Med Sci 30:suppl 1 (2015), S59–66.
43. Kluckow, M., Jeffery, M., Gill, A., Evans, N., A randomised placebo-controlled trial of early treatment of the patent ductus arteriosus. Arch Dis Child 99 (2014), F99–104.
44. Liebowitz, M., Koo, J., Wickremasinghe, A., Allen, I.E., Clyman, R.I., Effects of prophylactic indomethacin on vasopressor-dependent hypotension in extremely preterm infants. J Pediatr 182 (2017), 21–27 e2.
45. Kaempf, J.W., Wu, Y.X., Kaempf, A.J., Kaempf, A.M., Wang, L., Grunkemeier, G., What happens when the patent ductus arteriosus is treated less aggressively in very low birth weight infants?. J Perinatol 32 (2012), 344–348.
46. Kaempf, J.W., Huston, J., Wu, X.Y., Wang, L., Grunkemeier, G., Mischel, R., et al. Permissive tolerance of the patent ductus arteriosus may increase the risk of chronic lung disease. Res Rep Neonatol 3 (2013), 5–10.
47. Sadeck, L.S., Leone, C.R., Procianoy, R.S., Guinsburg, R., Marba, S.T., Martinez, F.E., et al. Effects of therapeutic approach on the neonatal evolution of very low birth weight infants with patent ductus arteriosus. J Pediatr (Rio J) 90 (2014), 616–623.
48. Chen, H.L., Yang, R.C., Lee, W.T., Lee, P.L., Hsu, J.H., Wu, J.R., et al. Lung function in very preterm infants with patent ductus arteriosus under conservative management: an observational study. BMC Pediatr, 15, 2015, 167.