Why septal motion is a marker of right ventricular failure in pulmonary arterial hypertension: Mechanistic analysis using a computer model

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 312, Issue 4, 2017, Pages H691-H700

  Palau Caballero, Georgina ^a   Walmsley, John ^a   Van Empel, Vanessa ^b   Lumens, Joost ^a   Delhaas, Tammo ^a  

^a MAASTRICHT UNIVERSITY   (Netherlands)

^b MAASTRICHT UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Circ Adapt; Left ventricular failure; Leftward ventricular septal bulging; Paradoxical interventricular septal motion; Transseptal pressure gradient

Indexed keywords

BIOLOGICAL MARKER;

ADULT; AORTA VALVE REGURGITATION; ARTICLE; CARDIAC PATIENT; CARDIOVASCULAR FUNCTION; CARDIOVASCULAR MORTALITY; COMPUTER MODEL; CONTROLLED STUDY; DIASTOLE; DISEASE SEVERITY; HEART AFTERLOAD; HEART CONTRACTION; HEART HEMODYNAMICS; HEART LEFT VENTRICLE FAILURE; HEART RIGHT VENTRICLE FAILURE; HEART RIGHT VENTRICLE HYPERTROPHY; HEART VENTRICLE FILLING; HEART VENTRICLE WALL; HUMAN; HUMAN TISSUE; HYPOTROPHY; LEFT VENTRICLE HYPOTROPHY; LUNG ARTERY PRESSURE; LUNG VASCULAR RESISTANCE; NONHUMAN; PRESSURE GRADIENT; PRIORITY JOURNAL; PULMONARY HYPERTENSION; PULMONARY VALVE INSUFFICIENCY; RAPID LEFTWARD SEPTAL MOTION; SYSTOLIC BLOOD PRESSURE; SYSTOLIC DYSFUNCTION; CARDIAC MUSCLE; COMPLICATION; COMPUTER SIMULATION; ETIOLOGY; HEART FAILURE; HEART RIGHT VENTRICLE FUNCTION; HEART SEPTUM; HEART VENTRICLE FUNCTION; LUNG CIRCULATION; METABOLISM; PATHOPHYSIOLOGY; PULMONARY ARTERY;

BIOMARKERS; COMPUTER SIMULATION; HEART FAILURE; HEART SEPTUM; HUMANS; HYPERTENSION, PULMONARY; MYOCARDIAL CONTRACTION; MYOCARDIUM; PULMONARY ARTERY; PULMONARY CIRCULATION; VENTRICULAR DYSFUNCTION, RIGHT; VENTRICULAR FUNCTION;

EID: 85017003077     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00596.2016     Document Type: Article

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