The discovery of Alzheimer-causing mutations in the APP gene and the formulation of the “amyloid cascade hypothesis”

FEBS Journal

Volumn 284, Issue 7, 2017, Pages 1040-1044

  Hardy, John ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

Alzheimer's disease; amyloid; APP; Down syndrome; genetics

Indexed keywords

AMYLOID PRECURSOR PROTEIN; COMPLEMENTARY DNA; APP PROTEIN, HUMAN; GENETIC MARKER;

ALZHEIMER DISEASE; APP GENE; CHROMOSOME 21; DISEASE ASSOCIATION; DNA LIBRARY; DOWN SYNDROME; GENE DUPLICATION; GENE MUTATION; GENE SEQUENCE; GENETIC ANALYSIS; GENETIC LINKAGE; GENETIC VARIABILITY; HUMAN; MOLECULAR CLONING; PATHOGENESIS; REVIEW; ARTIFACT; CHEMISTRY; GENE EXPRESSION; GENETIC MARKER; GENETICS; HISTORY; PATHOLOGY;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN PRECURSOR; ARTIFACTS; CHROMOSOMES, HUMAN, PAIR 21; DOWN SYNDROME; GENE DUPLICATION; GENE EXPRESSION; GENETIC MARKERS; HISTORY, 20TH CENTURY; HUMANS;

EID: 85016814394     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/febs.14004     Document Type: Review

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