The X to autosome expression ratio in haploid and diploid human embryonic stem cells

Molecular Biology and Evolution

Volumn 33, Issue 12, 2016, Pages 3104-3107

  Chen, Xiaoshu ^a,b   Zhang, Jianzhi ^b  

^a SUN YAT SEN UNIVERSITY   (China)

^b UNIVERSITY OF MICHIGAN   (United States)

Author keywords

Dosage balance; Dosage compensation; Evolution; Mammal; Sex chromosome

Indexed keywords

AUTOSOME; DIPLOIDY; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; HUMAN EMBRYONIC STEM CELL; MAMMAL; NONHUMAN; THINKING; UPREGULATION; X CHROMOSOME; CELL LINE; HAPLOIDY; PHYSIOLOGY; PROCEDURES; SEQUENCE ANALYSIS; X CHROMOSOMAL INHERITANCE; X CHROMOSOME INACTIVATION;

CELL LINE; CHROMOSOMES, HUMAN, X; DIPLOIDY; DOSAGE COMPENSATION, GENETIC; GENES, X-LINKED; HAPLOIDY; HUMAN EMBRYONIC STEM CELLS; HUMANS; SEQUENCE ANALYSIS, RNA; X CHROMOSOME INACTIVATION;

EID: 85016183703     PISSN: 07374038     EISSN: 15371719     Source Type: Journal    
DOI: 10.1093/molbev/msw187     Document Type: Article

References (17)

1. Carrel L, Willard HF. 2005. X-inactivation profile reveals extensive variability in X-linked gene expression in females. Nature 434:400-404.
2. Charlesworth B. 1996. The evolution of chromosomal sex determination and dosage compensation. Curr Biol. 6:149-162.
3. Chen X, Zhang J. 2015. No X-chromosome dosage compensation in human proteomes.Mol Biol Evol. 32:1456-1460.
4. Cunningham F, Amode MR, Barrell D, Beal K, Billis K, Brent S, Carvalho-Silva D, Clapham P, Coates G, Fitzgerald S, et al. 2015. Ensembl 2015. Nucleic Acids Res. 43:D662-D669.
5. Daish TJ, Grutzner F. 2010. Meiotic sex chromosome inactivation. In: Encyclopedia of life sciences. Chichester: John Wiley & Sons. p. 1-9.
6. He X, Zhang J. 2016. X-chromosome dosage compensation. In: Encyclopedia of life sciences. Chichester: John Wiley & Sons. p. 1-7.
7. Julien P, Brawand D, SoumillonM, Necsulea A, Liechti A, Schutz F, Daish T, Grutzner F, Kaessmann H. 2012. Mechanisms and evolutionary patterns of mammalian and avian dosage compensation. PLoS Biol. 10:e1001328.
8. Lin F, Xing K, Zhang J, He X. 2012. Expression reduction inmammalian X chromosome evolution refutes Ohno's hypothesis of dosage compensation. Proc Natl Acad Sci U S A. 109:11752-11757.
9. Nguyen DK, Disteche CM. 2006. Dosage compensation of the active X chromosome in mammals. Nat Genet. 38:47-53.
10. Ohno S. 1967. Sex chromosomes and sex-linked genes. New York: Springer-Verlag.
11. Payer B, Lee JT. 2008. X chromosome dosage compensation: how mammals keep the balance. Annu Rev Genet. 42:733-772.
12. Pessia E, Makino T, Bailly-Bechet M, McLysaght A, Marais GA. 2012. Mammalian X chromosome inactivation evolved as a dosagecompensation mechanism for dosage-sensitive genes on the X chromosome. Proc Natl Acad Sci U S A. 109:5346-5351.
13. Sagi I, Chia G, Golan-Lev T, Peretz M, Weissbein U, Sui L, Sauer MV, Yanuka O, Egli D, Benvenisty N. 2016. Derivation and differentiation of haploid human embryonic stem cells. Nature 532:107-111.
14. Sharp AJ, Stathaki E, Migliavacca E, Brahmachary M, Montgomery SB, Dupre Y, Antonarakis SE. 2011. DNA methylation profiles of human active and inactive X chromosomes. Genome Res. 21:1592-1600.
15. Turner JM. 2015. Meiotic silencing in mammals. Annu Rev Genet. 49:395-412.
16. Veitia RA, Veyrunes F, Bottani S, Birchler JA. 2015. X chromosome inactivation and active X upregulation in therian mammals: facts, questions, and hypotheses. J Mol Cell Biol. 7:2-11.
17. Xiong Y, Chen X, Chen Z, Wang X, Shi S, Wang X, Zhang J, He X. 2010. RNA sequencing shows no dosage compensation of the active Xchromosome. Nat Genet. 42:1043-1047.