Analytical sensitivity of current best-in-class malaria rapid diagnostic tests

Malaria Journal

Volumn 16, Issue 1, 2017, Pages

  Jimenez, Alfons ^a   Rees Channer, Roxanne R ^b   Perera, Rushini ^b   Gamboa, Dionicia ^c   Chiodini, Peter L ^b   González, Iveth J ^e   Mayor, Alfredo ^a,d   Ding, Xavier C ^e  

^a UNIVERSITY OF BARCELONA   (Spain)

^b HOSPITAL FOR TROPICAL DISEASES   (United Kingdom)

^c INSTITUTO DE MEDICINA TROPICAL ALEXANDER VON HUMBOLDT   (Peru)

^d Manhiça Health Research Center   (Mozambique)

^e Malaria Fever Program   (Switzerland)

Author keywords

Analytical sensitivity; HRP2; Malaria rapid diagnostic test; pLDH

Indexed keywords

HISTIDINE; HISTIDINE RICH PROTEIN 2; LACTATE DEHYDROGENASE; PROTOZOAL PROTEIN; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG; PARASITE ANTIGEN;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; LIMIT OF DETECTION; MALARIA RAPID TEST; NONHUMAN; PARASITE IDENTIFICATION; PLASMODIUM FALCIPARUM; PLASMODIUM VIVAX; SENSITIVITY ANALYSIS; ADULT; COMPARATIVE STUDY; DIAGNOSTIC TEST; EVALUATION STUDY; HUMAN; IMMUNOAFFINITY CHROMATOGRAPHY; IMMUNOLOGY; ISOLATION AND PURIFICATION; MALARIA; MALARIA FALCIPARUM; PLASMODIUM VIVAX MALARIA; PROCEDURES; SENSITIVITY AND SPECIFICITY; TIME FACTOR;

ADULT; ANTIGENS, PROTOZOAN; DIAGNOSTIC TESTS, ROUTINE; HUMANS; IMMUNOCHROMATOGRAPHY; MALARIA; MALARIA, FALCIPARUM; MALARIA, VIVAX; PLASMODIUM FALCIPARUM; PLASMODIUM VIVAX; SENSITIVITY AND SPECIFICITY; TIME FACTORS;

EID: 85016108036     PISSN: None     EISSN: 14752875     Source Type: Journal    
DOI: 10.1186/s12936-017-1780-5     Document Type: Article

References (16)

1. WHO. Parasitological confirmation of malaria diagnosis. Geneva: World Health Organization; 2009.
2. World Health Organization. World malaria report 2015. Geneva: World Health Organization; 2015.
3. Batwala V, Magnussen P, Hansen KS, Nuwaha F. Cost-effectiveness of malaria microscopy and rapid diagnostic tests versus presumptive diagnosis: implications for malaria control in Uganda. Malar J. 2011;10:372.
4. UNITAID. Malaria diagnostics technology and market landscape; 2016. p. 1-176.
5. Abba K, Kirkham AJ, Olliaro PL, Deeks JJ, Donegan S, Garner P, et al. Rapid diagnostic tests for diagnosing uncomplicated non-falciparum or Plasmodium vivax malaria in endemic countries. Cochrane Database Syst Rev. 2014;12:CD011431.
6. Abba K, Deeks JJ, Olliaro P, Naing CM, Jackson SM, Takwoingi Y. Rapid diagnostic tests for diagnosing uncomplicated P. falciparum malaria in endemic countries. Cochrane Database Syst Rev. 2011;7:08122.
7. Galatas B, Bassat Q, Mayor A. Malaria parasites in the asymptomatic: looking for the hay in the haystack. Trends Parasitol. 2016;32:296-308.
8. WHO. Malaria rapid diagnostic test performance: results of WHO product testing of malaria RDTs: round 6 (2014-2015). Geneva: World Health Organization; 2015. p. 1-154.
9. Trager W, Jensen JB. Human malaria parasites in continuous culture. Science. 1976;193:673-5.
10. Polley SD, González IJ, Mohamed D, Daly R, Bowers K, Watson J, et al. Clinical evaluation of a loop-mediated amplification kit for diagnosis of imported malaria. J Infect Dis. 2013;208:637-44.
11. Maltha J, Gillet P, Cnops L, van den Ende J, van Esbroeck M, Jacobs J. Malaria rapid diagnostic tests: Plasmodium falciparum infections with high parasite densities may generate false positive Plasmodium vivax pLDH lines. Malar J. 2010;9:198.
12. Baker J, McCarthy J, Gatton M, Kyle DE, Belizario V, Luchavez J, et al. Genetic diversity of Plasmodium falciparum histidine-rich protein 2 (PfHRP2) and its effect on the performance of PfHRP2-based rapid diagnostic tests. J Infect Dis. 2005;192:870-7.
13. Baker J, Ho M-F, Pelecanos A, Gatton M, Chen N, Abdullah S, et al. Global sequence variation in the histidine-rich proteins 2 and 3 of Plasmodium falciparum: implications for the performance of malaria rapid diagnostic tests. Malar J. 2010;9:129.
14. Pava Z, Echeverry DF, Díaz G, Murillo C. Large Variation in detection of histidine-rich protein 2 in Plasmodium falciparum isolates from Colombia. Am J Trop Med Hyg. 2010;83:834-7.
15. Rubach MP, Mukemba J, Florence S, John B, Crookston B, Lopansri BK, et al. Plasma Plasmodium falciparum histidine-rich protein-2 concentrations are associated with malaria severity and mortality in Tanzanian children. PLoS ONE. 2012;7:e35985.
16. Jang JW, Cho CH, Han E-T, An SSA, Lim CS. pLDH level of clinically isolated Plasmodium vivax and detection limit of pLDH based malaria rapid diagnostic test. Malar J. 2013;12:181.