Neural basis of impaired safety signaling in Obsessive Compulsive Disorder

Proceedings of the National Academy of Sciences of the United States of America

Volumn 114, Issue 12, 2017, Pages 3216-3221

  Apergis Schoute, Annemieke M ^a,b   Gillan, Claire M ^b,c   Fineberg, Naomi A ^b,d,e   Fernandez Egea, Emilio ^a,b   Sahakian, Barbara J ^a,b   Robbins, Trevor W ^a,b  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^c TRINITY COLLEGE DUBLIN   (Ireland)

^d HERTFORDSHIRE PARTNERSHIP UNIVERSITY NHS FOUNDATION TRUST   (United Kingdom)

^e UNIVERSITY OF HERTFORDSHIRE   (United Kingdom)

Author keywords

FMRI; Obsessive Compulsive Disorder; Pavlovian; Safety signals; VmPFC

Indexed keywords

AMYGDALA; ANXIETY; ARTICLE; ASSOCIATION; BOLD SIGNAL; CLINICAL ARTICLE; CONTROLLED STUDY; DORSAL ANTERIOR CINGULATE CORTEX; FUNCTIONAL CONNECTIVITY; FUNCTIONAL MAGNETIC RESONANCE IMAGING; FUNCTIONAL NEUROIMAGING; HUMAN; INSULA; OBSESSIVE COMPULSIVE DISORDER; PRIORITY JOURNAL; SAFETY; SALIENCE NETWORK; SKIN CONDUCTANCE; STIMULUS GENERALIZATION; THALAMUS; THREAT; VENTROMEDIAL PREFRONTAL CORTEX; ADULT; BRAIN; BRAIN CORTEX; BRAIN MAPPING; CASE CONTROL STUDY; CAUDATE NUCLEUS; DIAGNOSTIC IMAGING; ELECTRIC CONDUCTIVITY; FEMALE; FUNCTIONS OF THE SKIN AND ITS APPENDAGES; LEARNING; MALE; METABOLISM; MIDDLE AGED; NERVE CELL; NEUROIMAGING; NUCLEAR MAGNETIC RESONANCE IMAGING; PATHOPHYSIOLOGY; PROCEDURES; SIGNAL TRANSDUCTION; YOUNG ADULT;

ADULT; AMYGDALA; ANXIETY; BRAIN; BRAIN MAPPING; CASE-CONTROL STUDIES; CAUDATE NUCLEUS; CEREBRAL CORTEX; ELECTRIC CONDUCTIVITY; FEMALE; HUMANS; LEARNING; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; NEUROIMAGING; NEURONS; OBSESSIVE-COMPULSIVE DISORDER; SIGNAL TRANSDUCTION; SKIN PHYSIOLOGICAL PHENOMENA; YOUNG ADULT;

EID: 85016097682     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1609194114     Document Type: Article

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