메뉴 건너뛰기




Volumn 36, Issue 11, 2015, Pages 1341-1353

Common variants at the CHEK2 gene locus and risk of epithelial ovarian cancer

(156)  Lawrenson, Kate ay   Iversen, Edwin S b   Tyrer, Jonathan c   Weber, Rachel Palmieri d   Concannon, Patrick e   Hazelett, Dennis J f   Li, Qiyuan g   Marks, Jeffrey R d   Berchuck, Andrew h   Lee, Janet M a   Aben, Katja K H i,j   Anton Culver, Hoda k   Antonenkova, Natalia l   Bandera, Elisa V m   Bean, Yukie n,o   Beckmann, Matthias W p   Bisogna, Maria q   Bjorge, Line r,s   Bogdanova, Natalia t   Brinton, Louise A u   more..


Author keywords

[No Author keywords available]

Indexed keywords

CAMP RESPONSIVE ELEMENT BINDING PROTEIN 5; CHECKPOINT KINASE 2; COILED COIL DOMAIN CONTAINING 117; EXONUCLEASE 1; FANCONI ANEMIA GROUP A PROTEIN; HSCB MITOCHONDRIAL IRON SULFUR CLUSTER COCHAPERONE; MESSENGER RNA; TETRATRICOPEPTIDE REPEAT DOMAIN 28; TRANSCRIPTION FACTOR E2F2; TRANSCRIPTION FACTOR E2F4; TUMOR MARKER; UNCLASSIFIED DRUG; X BOX BINDING PROTEIN 1; ZINC AND RING FINGER 3; CHEK2 PROTEIN, HUMAN;

EID: 85016071187     PISSN: 01433334     EISSN: 14602180     Source Type: Journal    
DOI: 10.1093/carcin/bgv138     Document Type: Article
Times cited : (27)

References (51)
  • 1
    • 0003964363 scopus 로고    scopus 로고
    • American Cancer Society, Atlanta
    • American Cancer Society. (2012) Cancer Facts & Figures 2012. American Cancer Society, Atlanta.
    • (2012) Cancer Facts & Figures 2012
  • 2
    • 0034754436 scopus 로고    scopus 로고
    • Ovulation-induced DNA damage in ovarian surface epithelial cells of ewes: prospective regulatory mechanisms of repair/survival and apoptosis
    • Murdoch, W.J. et al. (2001) Ovulation-induced DNA damage in ovarian surface epithelial cells of ewes: prospective regulatory mechanisms of repair/survival and apoptosis. Biol. Reprod., 65, 1417–1424.
    • (2001) Biol. Reprod , vol.65 , pp. 1417-1424
    • Murdoch, W.J.1
  • 3
    • 84894035972 scopus 로고    scopus 로고
    • Exposure of fallopian tube epithelium to follicular fluid mimics carcinogenic changes in precursor lesions of serous papillary carcinoma
    • Bahar-Shany, K. et al. (2014) Exposure of fallopian tube epithelium to follicular fluid mimics carcinogenic changes in precursor lesions of serous papillary carcinoma. Gynecol. Oncol., 132, 322–327.
    • (2014) Gynecol. Oncol , vol.132 , pp. 322-327
    • Bahar-Shany, K.1
  • 4
    • 0030979632 scopus 로고    scopus 로고
    • Relationship between lifetime ovulatory cycles and overexpression of mutant p53 in epithelial ovarian cancer
    • Schildkraut, J.M. et al. (1997) Relationship between lifetime ovulatory cycles and overexpression of mutant p53 in epithelial ovarian cancer. J. Natl. Cancer Inst., 89, 932–938.
    • (1997) J. Natl. Cancer Inst , vol.89 , pp. 932-938
    • Schildkraut, J.M.1
  • 5
    • 0033213392 scopus 로고    scopus 로고
    • Brca1 controls homology-directed DNA repair
    • Moynahan, M.E. et al. (1999) Brca1 controls homology-directed DNA repair. Mol. Cell, 4, 511–518.
    • (1999) Mol. Cell , vol.4 , pp. 511-518
    • Moynahan, M.E.1
  • 6
    • 0006713602 scopus 로고
    • Identification of the breast cancer susceptibility gene BRCA2
    • Wooster, R. et al. (1995) Identification of the breast cancer susceptibility gene BRCA2. Nature, 378, 789–792.
    • (1995) Nature , vol.378 , pp. 789-792
    • Wooster, R.1
  • 7
    • 0028073794 scopus 로고
    • BRCA1 mutations in primary breast and ovarian carcinomas
    • Futreal, P.A. et al. (1994) BRCA1 mutations in primary breast and ovarian carcinomas. Science, 266, 120–122.
    • (1994) Science , vol.266 , pp. 120-122
    • Futreal, P.A.1
  • 8
    • 0028113345 scopus 로고
    • A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1
    • Miki, Y. et al. (1994) A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1. Science, 266, 66–71.
    • (1994) Science , vol.266 , pp. 66-71
    • Miki, Y.1
  • 9
    • 84905666270 scopus 로고    scopus 로고
    • The contribution of deleterious germline mutations in BRCA1, BRCA2 and the mismatch repair genes to ovarian cancer in the population
    • Song, H. et al. (2014) The contribution of deleterious germline mutations in BRCA1, BRCA2 and the mismatch repair genes to ovarian cancer in the population. Hum. Mol. Genet., 23, 4703–4709.
    • (2014) Hum. Mol. Genet , vol.23 , pp. 4703-4709
    • Song, H.1
  • 10
    • 77951720395 scopus 로고    scopus 로고
    • Germline mutations in breast and ovarian cancer pedigrees establish RAD51C as a human cancer susceptibility gene
    • Meindl, A. et al. (2010) Germline mutations in breast and ovarian cancer pedigrees establish RAD51C as a human cancer susceptibility gene. Nat. Genet., 42, 410–414.
    • (2010) Nat. Genet , vol.42 , pp. 410-414
    • Meindl, A.1
  • 11
    • 80052264429 scopus 로고    scopus 로고
    • Germline mutations in RAD51D confer susceptibility to ovarian cancer
    • Loveday, C. et al. (2011) Germline mutations in RAD51D confer susceptibility to ovarian cancer. Nat. Genet., 43, 879–882.
    • (2011) Nat. Genet , vol.43 , pp. 879-882
    • Loveday, C.1
  • 12
    • 80054973810 scopus 로고    scopus 로고
    • Mutations in BRIP1 confer high risk of ovarian cancer
    • Rafnar, T. et al. (2011) Mutations in BRIP1 confer high risk of ovarian cancer. Nat. Genet., 43, 1104–1107.
    • (2011) Nat. Genet , vol.43 , pp. 1104-1107
    • Rafnar, T.1
  • 13
    • 69349102630 scopus 로고    scopus 로고
    • A genome-wide association study identifies a new ovarian cancer susceptibility locus on 9p22.2
    • Song, H. et al. (2009) A genome-wide association study identifies a new ovarian cancer susceptibility locus on 9p22.2. Nat. Genet., 41, 996–1000.
    • (2009) Nat. Genet , vol.41 , pp. 996-1000
    • Song, H.1
  • 14
    • 77957571905 scopus 로고    scopus 로고
    • A genome-wide association study identifies susceptibility loci for ovarian cancer at 2q31 and 8q24
    • Goode, E.L. et al. (2010) A genome-wide association study identifies susceptibility loci for ovarian cancer at 2q31 and 8q24. Nat. Genet., 42, 874–879.
    • (2010) Nat. Genet , vol.42 , pp. 874-879
    • Goode, E.L.1
  • 15
    • 77957584092 scopus 로고    scopus 로고
    • Common variants at 19p13 are associated with susceptibility to ovarian cancer
    • Bolton, K.L. et al. (2010) Common variants at 19p13 are associated with susceptibility to ovarian cancer. Nat. Genet., 42, 880–884.
    • (2010) Nat. Genet , vol.42 , pp. 880-884
    • Bolton, K.L.1
  • 16
    • 84875707717 scopus 로고    scopus 로고
    • GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer
    • Pharoah, P.D. et al. (2013) GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer. Nat. Genet., 45, 362–370.
    • (2013) Nat. Genet , vol.45 , pp. 362-370
    • Pharoah, P.D.1
  • 17
    • 84875908264 scopus 로고    scopus 로고
    • Identification and molecular characterization of a new ovarian cancer susceptibility locus at 17q21.31
    • Permuth-Wey, J. et al. (2013) Identification and molecular characterization of a new ovarian cancer susceptibility locus at 17q21.31. Nat. Commun., 4, 16–27.
    • (2013) Nat. Commun , vol.4 , pp. 16-27
    • Permuth-Wey, J.1
  • 18
    • 84875717832 scopus 로고    scopus 로고
    • Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer
    • Bojesen, S.E. et al. (2013) Multiple independent variants at the TERT locus are associated with telomere length and risks of breast and ovarian cancer. Nat. Genet., 45, 371–384.
    • (2013) Nat. Genet , vol.45 , pp. 371-384
    • Bojesen, S.E.1
  • 19
    • 84875904387 scopus 로고    scopus 로고
    • Epigenetic analysis leads to identification of HNF1B as a subtype-specific susceptibility gene for ovarian cancer
    • Shen, H. et al. (2013) Epigenetic analysis leads to identification of HNF1B as a subtype-specific susceptibility gene for ovarian cancer. Nat. Commun., 4, 16–28.
    • (2013) Nat. Commun , vol.4 , pp. 16-28
    • Shen, H.1
  • 20
    • 84907365949 scopus 로고    scopus 로고
    • Genome-wide association study identifies new susceptibility loci for epithelial ovarian cancer in Han Chinese women
    • Chen, K. et al. (2014) Genome-wide association study identifies new susceptibility loci for epithelial ovarian cancer in Han Chinese women. Nat. Commun., 5, 4682.
    • (2014) Nat. Commun , vol.5 , pp. 4682
    • Chen, K.1
  • 21
    • 84929171835 scopus 로고    scopus 로고
    • Identification of six new susceptibility loci for invasive epithelial ovarian cancer
    • Kuchenbaecker, K.B. et al. (2015) Identification of six new susceptibility loci for invasive epithelial ovarian cancer. Nat. Genet., 47, 164–171.
    • (2015) Nat. Genet , vol.47 , pp. 164-171
    • Kuchenbaecker, K.B.1
  • 22
    • 84875703379 scopus 로고    scopus 로고
    • Large-scale genotyping identifies 41 new loci associated with breast cancer risk
    • Michailidou, K. et al. (2013) Large-scale genotyping identifies 41 new loci associated with breast cancer risk. Nat. Genet., 45, 353–361.
    • (2013) Nat. Genet , vol.45 , pp. 353-361
    • Michailidou, K.1
  • 23
    • 0034624718 scopus 로고    scopus 로고
    • hCds1-mediated phosphorylation of BRCA1 regulates the DNA damage response
    • Lee, J.S. et al. (2000) hCds1-mediated phosphorylation of BRCA1 regulates the DNA damage response. Nature, 404, 201–204.
    • (2000) Nature , vol.404 , pp. 201-204
    • Lee, J.S.1
  • 24
    • 3042582651 scopus 로고    scopus 로고
    • CHEK2*1100delC and susceptibility to breast cancer: a collaborative analysis involving 10,860 breast cancer cases and 9,065 controls from 10 studies
    • Consortium, C.B.C.C.-C. (2004) CHEK2*1100delC and susceptibility to breast cancer: a collaborative analysis involving 10,860 breast cancer cases and 9,065 controls from 10 studies. Am. J. Hum. Genet., 74, 1175–1182.
    • (2004) Am. J. Hum. Genet , vol.74 , pp. 1175-1182
    • Consortium, C.B.C.C.-C.1
  • 25
    • 81055126264 scopus 로고    scopus 로고
    • Mutations in 12 genes for inherited ovarian, fallopian tube, and peritoneal carcinoma identified by massively parallel sequencing
    • Walsh, T. et al. (2011) Mutations in 12 genes for inherited ovarian, fallopian tube, and peritoneal carcinoma identified by massively parallel sequencing. Proc. Natl. Acad. Sci. USA, 108, 18032–18037.
    • (2011) Proc. Natl. Acad. Sci. USA , vol.108 , pp. 18032-18037
    • Walsh, T.1
  • 26
    • 77956331205 scopus 로고    scopus 로고
    • Association between DNA damage response and repair genes and risk of invasive serous ovarian cancer
    • Schildkraut, J.M. et al. (2010) Association between DNA damage response and repair genes and risk of invasive serous ovarian cancer. PLoS One, 5, e10061.
    • (2010) PLoS One , vol.5 , pp. e10061
    • Schildkraut, J.M.1
  • 27
    • 24044554210 scopus 로고    scopus 로고
    • Human DNA repair genes, 2005
    • Wood, R.D. et al. (2005) Human DNA repair genes, 2005. Mutat. Res., 577, 275–283.
    • (2005) Mutat. Res , vol.577 , pp. 275-283
    • Wood, R.D.1
  • 28
    • 67651222400 scopus 로고    scopus 로고
    • A flexible and accurate genotype imputation method for the next generation of genome-wide association studies
    • Howie, B.N. et al. (2009) A flexible and accurate genotype imputation method for the next generation of genome-wide association studies. PLoS Genet., 5, e1000529.
    • (2009) PLoS Genet , vol.5 , pp. e1000529
    • Howie, B.N.1
  • 29
    • 84885018609 scopus 로고    scopus 로고
    • Systematic identification of trans eQTLs as putative drivers of known disease associations
    • Westra, H.J. et al. (2013) Systematic identification of trans eQTLs as putative drivers of known disease associations. Nat. Genet., 45, 1238–1243.
    • (2013) Nat. Genet , vol.45 , pp. 1238-1243
    • Westra, H.J.1
  • 30
    • 84866087898 scopus 로고    scopus 로고
    • Primary culture and immortalization of human fallopian tube secretory epithelial cells
    • Karst, A.M. et al. (2012) Primary culture and immortalization of human fallopian tube secretory epithelial cells. Nat. Protoc., 7, 1755–1764.
    • (2012) Nat. Protoc , vol.7 , pp. 1755-1764
    • Karst, A.M.1
  • 31
    • 33846976549 scopus 로고    scopus 로고
    • Functional characterization of a novel BRCA1-null ovarian cancer cell line in response to ionizing radiation
    • DelloRusso, C. et al. (2007) Functional characterization of a novel BRCA1-null ovarian cancer cell line in response to ionizing radiation. Mol. Cancer Res., 5, 35–45.
    • (2007) Mol. Cancer Res , vol.5 , pp. 35-45
    • DelloRusso, C.1
  • 32
    • 84896695503 scopus 로고    scopus 로고
    • Comprehensive functional annotation of 77 prostate cancer risk loci
    • Hazelett, D.J. et al. (2014) Comprehensive functional annotation of 77 prostate cancer risk loci. PLoS Genet., 10, e1004–102.
    • (2014) PLoS Genet , vol.10 , pp. e1004-e1102
    • Hazelett, D.J.1
  • 33
    • 65349087874 scopus 로고    scopus 로고
    • In vitro three-dimensional modelling of human ovarian surface epithelial cells
    • Lawrenson, K. et al. (2009) In vitro three-dimensional modelling of human ovarian surface epithelial cells. Cell Prolif., 42, 385–393.
    • (2009) Cell Prolif , vol.42 , pp. 385-393
    • Lawrenson, K.1
  • 34
    • 3042592008 scopus 로고    scopus 로고
    • A modified medium that significantly improves the growth of human normal ovarian surface epithelial (OSE) cells in vitro
    • Li, N.F. et al. (2004) A modified medium that significantly improves the growth of human normal ovarian surface epithelial (OSE) cells in vitro. Lab. Invest., 84, 923–931.
    • (2004) Lab. Invest , vol.84 , pp. 923-931
    • Li, N.F.1
  • 35
    • 84873288058 scopus 로고    scopus 로고
    • Integrative eQTL-based analyses reveal the biology of breast cancer risk loci
    • Li, Q. et al. (2013) Integrative eQTL-based analyses reveal the biology of breast cancer risk loci. Cell, 152, 633–641.
    • (2013) Cell , vol.152 , pp. 633-641
    • Li, Q.1
  • 36
    • 84876529535 scopus 로고    scopus 로고
    • Factorbook.org: a Wiki-based database for transcription factor-binding data generated by the ENCODE consortium
    • Wang, J. et al. (2013) Factorbook.org: a Wiki-based database for transcription factor-binding data generated by the ENCODE consortium. Nucleic Acids Res., 41, D171–D176.
    • (2013) Nucleic Acids Res , vol.41 , pp. D171-D176
    • Wang, J.1
  • 37
    • 84936771937 scopus 로고    scopus 로고
    • Cell type specific enrichment of risk associated regulatory elements at ovarian cancer susceptibility loci
    • Coetzee, S.G. et al. (2015) Cell type specific enrichment of risk associated regulatory elements at ovarian cancer susceptibility loci. Hum. Mol. Genet, 24, 3595–3607.
    • (2015) Hum. Mol. Genet , vol.24 , pp. 3595-3607
    • Coetzee, S.G.1
  • 38
    • 84874809425 scopus 로고    scopus 로고
    • HOCOMOCO: a comprehensive collection of human transcription factor binding sites models
    • Kulakovskiy, I.V. et al. (2013) HOCOMOCO: a comprehensive collection of human transcription factor binding sites models. Nucleic Acids Res., 41, D195–D202.
    • (2013) Nucleic Acids Res , vol.41 , pp. D195-D202
    • Kulakovskiy, I.V.1
  • 39
    • 84868199288 scopus 로고    scopus 로고
    • A novel big protein TPRBK possessing 25 units of TPR motif is essential for the progress of mitosis and cytokinesis
    • Izumiyama, T. et al. (2012) A novel big protein TPRBK possessing 25 units of TPR motif is essential for the progress of mitosis and cytokinesis. Gene, 511, 202–217.
    • (2012) Gene , vol.511 , pp. 202-217
    • Izumiyama, T.1
  • 40
    • 77956513437 scopus 로고    scopus 로고
    • Characterization of the human HSC20, an unusual DnaJ type III protein, involved in iron-sulfur cluster biogenesis
    • Uhrigshardt, H. et al. (2010) Characterization of the human HSC20, an unusual DnaJ type III protein, involved in iron-sulfur cluster biogenesis. Hum. Mol. Genet., 19, 3816–3834.
    • (2010) Hum. Mol. Genet , vol.19 , pp. 3816-3834
    • Uhrigshardt, H.1
  • 41
    • 84860765166 scopus 로고    scopus 로고
    • ZNRF3 promotes Wnt receptor turnover in an R-spondin-sensitive manner
    • Hao, H.X. et al. (2012) ZNRF3 promotes Wnt receptor turnover in an R-spondin-sensitive manner. Nature, 485, 195–200.
    • (2012) Nature , vol.485 , pp. 195-200
    • Hao, H.X.1
  • 42
    • 84946040120 scopus 로고    scopus 로고
    • COSMIC: exploring the world’s knowledge of somatic mutations in human cancer
    • Forbes, S.A. et al. (2014) COSMIC: exploring the world’s knowledge of somatic mutations in human cancer. Nucleic Acids Res, 43, D805–D811.
    • (2014) Nucleic Acids Res , vol.43 , pp. D805-D811
    • Forbes, S.A.1
  • 43
    • 80053155727 scopus 로고    scopus 로고
    • Modelling genetic and clinical heterogeneity in epithelial ovarian cancers
    • Lawrenson, K. et al. (2011) Modelling genetic and clinical heterogeneity in epithelial ovarian cancers. Carcinogenesis, 32, 1540–1549.
    • (2011) Carcinogenesis , vol.32 , pp. 1540-1549
    • Lawrenson, K.1
  • 44
    • 84875739291 scopus 로고    scopus 로고
    • Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array
    • Eeles, R.A. et al. (2013) Identification of 23 new prostate cancer susceptibility loci using the iCOGS custom genotyping array. Nat. Genet., 45, 385–391.
    • (2013) Nat. Genet , vol.45 , pp. 385-391
    • Eeles, R.A.1
  • 45
    • 84871969762 scopus 로고    scopus 로고
    • Large-scale association analysis identifies new risk loci for coronary artery disease
    • Deloukas, P. et al. (2013) Large-scale association analysis identifies new risk loci for coronary artery disease. Nat. Genet., 45, 25–33.
    • (2013) Nat. Genet , vol.45 , pp. 25-33
    • Deloukas, P.1
  • 46
    • 84874789647 scopus 로고    scopus 로고
    • Egr-1 mediates epidermal growth factor-induced downregulation of E-cadherin expression via Slug in human ovarian cancer cells
    • Cheng, J.C. et al. (2013) Egr-1 mediates epidermal growth factor-induced downregulation of E-cadherin expression via Slug in human ovarian cancer cells. Oncogene, 32, 1041–1049.
    • (2013) Oncogene , vol.32 , pp. 1041-1049
    • Cheng, J.C.1
  • 47
    • 33749031535 scopus 로고    scopus 로고
    • The many facets of the Wilms' tumour gene, WT1
    • Hohenstein, P. et al. (2006) The many facets of the Wilms' tumour gene, WT1. Hum. Mol. Genet., 15, R196–R201.
    • (2006) Hum. Mol. Genet , vol.15 , pp. R196-R201
    • Hohenstein, P.1
  • 48
    • 79959838081 scopus 로고    scopus 로고
    • Integrated genomic analyses of ovarian carcinoma
    • Network, C.G.A.R. (2011) Integrated genomic analyses of ovarian carcinoma. Nature, 474, 609–615.
    • (2011) Nature , vol.474 , pp. 609-615
    • Network, C.G.A.R.1
  • 49
    • 33749000596 scopus 로고    scopus 로고
    • The role of BRCA1 in transcriptional regulation and cell cycle control
    • Mullan, P.B. et al. (2006) The role of BRCA1 in transcriptional regulation and cell cycle control. Oncogene, 25, 5854–5863.
    • (2006) Oncogene , vol.25 , pp. 5854-5863
    • Mullan, P.B.1
  • 50
    • 84860389647 scopus 로고    scopus 로고
    • Rare, evolutionarily unlikely missense substitutions in CHEK2 contribute to breast cancer susceptibility: results from a breast cancer family registry case-control mutation-screening study
    • Le Calvez-Kelm, F. et al. (2011) Rare, evolutionarily unlikely missense substitutions in CHEK2 contribute to breast cancer susceptibility: results from a breast cancer family registry case-control mutation-screening study. Breast Cancer Res., 13, R6.
    • (2011) Breast Cancer Res , vol.13 , pp. R6
    • Le Calvez-Kelm, F.1
  • 51
    • 78649688536 scopus 로고    scopus 로고
    • Analysis of the 10q11 cancer risk locus implicates MSMB and NCOA4 in human prostate tumorigenesis
    • Pomerantz, M.M. et al. (2010) Analysis of the 10q11 cancer risk locus implicates MSMB and NCOA4 in human prostate tumorigenesis. PLoS Genet., 6, e1001204.
    • (2010) PLoS Genet , vol.6 , pp. e1001204
    • Pomerantz, M.M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.