Deletion of the type-1 interferon receptor in APPSWE/PS1ΔE9 mice preserves cognitive function and alters glial phenotype

Acta neuropathologica communications

Volumn 4, Issue 1, 2016, Pages 72-

  Minter, Myles R ^a   Moore, Zachery ^a   Zhang, Moses ^a   Brody, Kate M ^a   Jones, Nigel C ^a   Shultz, Sandy R ^a   Taylor, Juliet M ^a   Crack, Peter J ^a  

^a UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

Alzheimer s disease; Amyloid ; Cognition; Microglial polarization; Neuro inflammation; Type 1 interferons

Indexed keywords

ALPHA BETA INTERFERON RECEPTOR; AMYLOID BETA PROTEIN; AMYLOID BETA-PROTEIN (1-42); IFNAR1 PROTEIN, MOUSE; PEPTIDE FRAGMENT;

ALZHEIMER DISEASE; AMYLOID PLAQUE; ANIMAL; BRAIN CORTEX; C57BL MOUSE; CELL CULTURE; COGNITION; DEFICIENCY; DISEASE MODEL; FEMALE; GENETICS; GLIA; GLIOSIS; HIPPOCAMPUS; HUMAN; IMMUNOLOGY; MALE; MAZE TEST; METABOLISM; MOUSE; NERVE CELL; PATHOLOGY; PHYSIOLOGY; PSYCHOLOGY; SPATIAL MEMORY; TRANSGENIC MOUSE;

ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; ANIMALS; CELLS, CULTURED; CEREBRAL CORTEX; COGNITION; DISEASE MODELS, ANIMAL; FEMALE; GLIOSIS; HIPPOCAMPUS; HUMANS; MALE; MAZE LEARNING; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; NEUROGLIA; NEURONS; PEPTIDE FRAGMENTS; PLAQUE, AMYLOID; RECEPTOR, INTERFERON ALPHA-BETA; SPATIAL MEMORY;

EID: 85015834418     PISSN: None     EISSN: 20515960     Source Type: Journal    
DOI: 10.1186/s40478-016-0341-4     Document Type: Article

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