Cancer-associated fibroblasts release exosomal microRNAs that dictate an aggressive phenotype in breast cancer

Oncotarget

Volumn 8, Issue 12, 2017, Pages 19592-19608

  Donnarumma, Elvira ^a   Fiore, Danilo ^b   Nappa, Martina ^b   Roscigno, Giuseppina ^b   Adamo, Assunta ^b   Iaboni, Margherita ^b   Russo, Valentina ^b   Affinito, Alessandra ^b   Puoti, Ilaria ^b   Quintavalle, Cristina ^d   Rienzo, Anna ^c   Piscuoglio, Salvatore ^d   Thomas, Renato ^e   Condorelli, Gerolama ^b,c  

^a IRCCS SDN   (Italy)

^b UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^c CNR   (Italy)

^d UNIVERSITY HOSPITAL BASEL   (Switzerland)

^e Clinica Mediterranea   (Italy)

Author keywords

Breast cancer; Cancer associated fibroblasts; Exosomes; Microenvironment; MicroRNAs

Indexed keywords

MICRORNA; MICRORNA 143; MICRORNA 21; MICRORNA 378E; UNCLASSIFIED DRUG; MIRN143 MICRORNA, HUMAN; MIRN21 MICRORNA, HUMAN; MIRN378 MICRORNA, HUMAN; TUMOR MARKER;

ANCHORAGE INDEPENDENT GROWTH; ARTICLE; BREAST CANCER; BREAST CANCER CELL LINE; CANCER ASSOCIATED FIBROBLAST; CANCER STEM CELL; CELL DEDIFFERENTIATION; CONTROLLED STUDY; EPITHELIAL MESENCHYMAL TRANSITION; EXOSOME; GENE EXPRESSION PROFILING; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOFLUORESCENCE; INTRACELLULAR SIGNALING; PHENOTYPE; APOPTOSIS; BREAST TUMOR; CANCER STAGING; CELL PROLIFERATION; FEMALE; GENE EXPRESSION REGULATION; GENETICS; PATHOLOGY; PROGNOSIS; SIGNAL TRANSDUCTION; TUMOR CELL CULTURE; TUMOR MICROENVIRONMENT;

APOPTOSIS; BIOMARKERS, TUMOR; BREAST NEOPLASMS; CANCER-ASSOCIATED FIBROBLASTS; CELL PROLIFERATION; EPITHELIAL-MESENCHYMAL TRANSITION; EXOSOMES; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MICRORNAS; NEOPLASM STAGING; PHENOTYPE; PROGNOSIS; SIGNAL TRANSDUCTION; TUMOR CELLS, CULTURED; TUMOR MICROENVIRONMENT;

EID: 85015741248     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.14752     Document Type: Article

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