Variations in Infant CYP2B6 Genotype Associated with the Need for Pharmacological Treatment for Neonatal Abstinence Syndrome in Infants of Methadone-Maintained Opioid-Dependent Mothers

American Journal of Perinatology

Volumn 34, Issue 9, 2017, Pages 918-921

  Mactier, Helen ^a   McLaughlin, Poppy ^b   Gillis, Cheryl ^a   Osselton, Michael David ^b  

^a UK   (United Kingdom)

^b BOURNEMOUTH UNIVERSITY   (United Kingdom)

Author keywords

genotype; methadone; neonatal abstinence syndrome; newborn

Indexed keywords

CATECHOL METHYLTRANSFERASE; CYTOCHROME P450 2B6; CYTOCHROME P450 2D6; METHADONE; MORPHINE; PHENOBARBITAL; CYP2B6 PROTEIN, HUMAN; NARCOTIC ANALGESIC AGENT;

ADD ON THERAPY; ADULT; ARTICLE; BIRTH WEIGHT; BLOOD SAMPLING; CLINICAL ARTICLE; COHORT ANALYSIS; DISEASE SEVERITY; DRUG BLOOD LEVEL; DRUG DOSE INCREASE; DRUG DOSE REDUCTION; FEMALE; GENETIC VARIATION; GENOTYPE; HOMOZYGOSITY; HUMAN; LENGTH OF STAY; MAINTENANCE THERAPY; METHADONE TREATMENT; NEONATAL ABSTINENCE SYNDROME; NEWBORN; OBSERVATIONAL STUDY; OPIATE ADDICTION; ORAL BIOPSY; PILOT STUDY; PRESCRIPTION; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM; TREATMENT DURATION; COMPLICATION; GENETICS; MALE; OPIATE SUBSTITUTION TREATMENT; PREGNANCY; PREGNANCY COMPLICATION; PRENATAL EXPOSURE; UNITED KINGDOM;

ADULT; ANALGESICS, OPIOID; COHORT STUDIES; CYTOCHROME P-450 CYP2B6; FEMALE; GENETIC VARIATION; HUMANS; INFANT, NEWBORN; MALE; METHADONE; NEONATAL ABSTINENCE SYNDROME; OPIATE SUBSTITUTION TREATMENT; OPIOID-RELATED DISORDERS; PREGNANCY; PREGNANCY COMPLICATIONS; PRENATAL EXPOSURE DELAYED EFFECTS; UNITED KINGDOM;

EID: 85015734793     PISSN: 07351631     EISSN: 10988785     Source Type: Journal    
DOI: 10.1055/s-0037-1600917     Document Type: Article

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