-
1
-
-
77954801079
-
Improved survival with ipilimumab in patients with metastatic melanoma
-
PMID: 20525992
-
Hodi FS, O'Day SJ, McDermott DF, Weber RW, Sosman JA, Haanen JB, Gonzalez R, Robert C, Schadendorf D, Hassel JC, Akerley W, van den Eertwegh AJ, Lutzky J, Lorigan P, Vaubel JM, Linette GP, Hogg D, Ottensmeier CH, Lebbé C, Peschel C, Quirt I, Clark JI, Wolchok JD, Weber JS, Tian J, Yellin MJ, Nichol GM, Hoos A, Urba WJ. Improved survival with ipilimumab in patients with metastatic melanoma. N Engl J Med 2010; 363: 711-723 [PMID: 20525992 DOI: 10.1056/NEJMoa1003466]
-
(2010)
N Engl J Med
, vol.363
, pp. 711-723
-
-
Hodi, F.S.1
O'Day, S.J.2
McDermott, D.F.3
Weber, R.W.4
Sosman, J.A.5
Haanen, J.B.6
Gonzalez, R.7
Robert, C.8
Schadendorf, D.9
Hassel, J.C.10
Akerley, W.11
Van Den Eertwegh, A.J.12
Lutzky, J.13
Lorigan, P.14
Vaubel, J.M.15
Linette, G.P.16
Hogg, D.17
Ottensmeier, C.H.18
Lebbé, C.19
Peschel, C.20
Quirt, I.21
Clark, J.I.22
Wolchok, J.D.23
Weber, J.S.24
Tian, J.25
Yellin, M.J.26
Nichol, G.M.27
Hoos, A.28
Urba, W.J.29
more..
-
2
-
-
79959772576
-
Ipilimumab plus dacarbazine for previously untreated metastatic melanoma
-
PMID: 21639810
-
Robert C, Thomas L, Bondarenko I, O'Day S, Weber J, Garbe C, Lebbe C, Baurain JF, Testori A, Grob JJ, Davidson N, Richards J, Maio M, Hauschild A, Miller WH, Gascon P, Lotem M, Harmankaya K, Ibrahim R, Francis S, Chen TT, Humphrey R, Hoos A, Wolchok JD. Ipilimumab plus dacarbazine for previously untreated metastatic melanoma. N Engl J Med 2011; 364: 2517-2526 [PMID: 21639810 DOI: 10.1056/NEJMoa1104621]
-
(2011)
N Engl J Med
, vol.364
, pp. 2517-2526
-
-
Robert, C.1
Thomas, L.2
Bondarenko, I.3
O'Day, S.4
Weber, J.5
Garbe, C.6
Lebbe, C.7
Baurain, J.F.8
Testori, A.9
Grob, J.J.10
Davidson, N.11
Richards, J.12
Maio, M.13
Hauschild, A.14
Miller, W.H.15
Gascon, P.16
Lotem, M.17
Harmankaya, K.18
Ibrahim, R.19
Francis, S.20
Chen, T.T.21
Humphrey, R.22
Hoos, A.23
Wolchok, J.D.24
more..
-
3
-
-
75249100054
-
Ipilimumab monotherapy in patients with pretreated advanced melanoma: A randomised, double-blind, multicentre, phase 2, doseranging study
-
PMID: 20004617
-
Wolchok JD, Neyns B, Linette G, Negrier S, Lutzky J, Thomas L, Waterfield W, Schadendorf D, Smylie M, Guthrie T, Grob JJ, Chesney J, Chin K, Chen K, Hoos A, O'Day SJ, Lebbé C. Ipilimumab monotherapy in patients with pretreated advanced melanoma: a randomised, double-blind, multicentre, phase 2, doseranging study. Lancet Oncol 2010; 11: 155-164 [PMID: 20004617 DOI: 10.1016/S1470-2045(09)70334-1]
-
(2010)
Lancet Oncol
, vol.11
, pp. 155-164
-
-
Wolchok, J.D.1
Neyns, B.2
Linette, G.3
Negrier, S.4
Lutzky, J.5
Thomas, L.6
Waterfield, W.7
Schadendorf, D.8
Smylie, M.9
Guthrie, T.10
Grob, J.J.11
Chesney, J.12
Chin, K.13
Chen, K.14
Hoos, A.15
O'Day, S.J.16
Lebbé, C.17
-
4
-
-
77955256254
-
Efficacy and safety of ipilimumab monotherapy in patients with pretreated advanced melanoma: A multicenter singlearm phase II study
-
PMID: 20147741
-
O'Day SJ, Maio M, Chiarion-Sileni V, Gajewski TF, Pehamberger H, Bondarenko IN, Queirolo P, Lundgren L, Mikhailov S, Roman L, Verschraegen C, Humphrey R, Ibrahim R, de Pril V, Hoos A, Wolchok JD. Efficacy and safety of ipilimumab monotherapy in patients with pretreated advanced melanoma: a multicenter singlearm phase II study. Ann Oncol 2010; 21: 1712-1717 [PMID: 20147741 DOI: 10.1093/annonc/mdq013]
-
(2010)
Ann Oncol
, vol.21
, pp. 1712-1717
-
-
O'Day, S.J.1
Maio, M.2
Chiarion-Sileni, V.3
Gajewski, T.F.4
Pehamberger, H.5
Bondarenko, I.N.6
Queirolo, P.7
Lundgren, L.8
Mikhailov, S.9
Roman, L.10
Verschraegen, C.11
Humphrey, R.12
Ibrahim, R.13
De Pril, V.14
Hoos, A.15
Wolchok, J.D.16
-
5
-
-
69949095926
-
A randomized, double-blind, placebo-controlled, phase II study comparing the tolerability and efficacy of ipilimumab administered with or without prophylactic budesonide in patients with unresectable stage III or IV melanoma
-
PMID: 19671877
-
Weber J, Thompson JA, Hamid O, Minor D, Amin A, Ron I, Ridolfi R, Assi H, Maraveyas A, Berman D, Siegel J, O'Day SJ. A randomized, double-blind, placebo-controlled, phase II study comparing the tolerability and efficacy of ipilimumab administered with or without prophylactic budesonide in patients with unresectable stage III or IV melanoma. Clin Cancer Res 2009; 15: 5591-5598 [PMID: 19671877 DOI: 10.1158/1078-0432. CCR-09-1024]
-
(2009)
Clin Cancer Res
, vol.15
, pp. 5591-5598
-
-
Weber, J.1
Thompson, J.A.2
Hamid, O.3
Minor, D.4
Amin, A.5
Ron, I.6
Ridolfi, R.7
Assi, H.8
Maraveyas, A.9
Berman, D.10
Siegel, J.11
O'Day, S.J.12
-
6
-
-
84864052441
-
Management of immunerelated adverse events and kinetics of response with ipilimumab
-
PMID: 22614989
-
Weber JS, Kähler KC, Hauschild A. Management of immunerelated adverse events and kinetics of response with ipilimumab. J Clin Oncol 2012; 30: 2691-2697 [PMID: 22614989 DOI: 10.1200/JCO.2012.41.6750]
-
(2012)
J Clin Oncol
, vol.30
, pp. 2691-2697
-
-
Weber, J.S.1
Kähler, K.C.2
Hauschild, A.3
-
7
-
-
77953635401
-
Refractory colitis following anti-CTLA4 antibody therapy: Analysis of mucosal FOXP3+ T cells
-
PMID: 19507029
-
Lord JD, Hackman RC, Moklebust A, Thompson JA, Higano CS, Chielens D, Steinbach G, McDonald GB. Refractory colitis following anti-CTLA4 antibody therapy: analysis of mucosal FOXP3+ T cells. Dig Dis Sci 2010; 55: 1396-1405 [PMID: 19507029 DOI: 10.1007/s10620-009-0839-8]
-
(2010)
Dig Dis Sci
, vol.55
, pp. 1396-1405
-
-
Lord, J.D.1
Hackman, R.C.2
Moklebust, A.3
Thompson, J.A.4
Higano, C.S.5
Chielens, D.6
Steinbach, G.7
McDonald, G.B.8
-
8
-
-
67650848410
-
Infliximab in the treatment of anti-CTLA4 antibody (ipilimumab) induced immune-related colitis
-
PMID: 19538054
-
Minor DR, Chin K, Kashani-Sabet M. Infliximab in the treatment of anti-CTLA4 antibody (ipilimumab) induced immune-related colitis. Cancer Biother Radiopharm 2009; 24: 321-325 [PMID: 19538054 DOI: 10.1089/cbr.2008.0607]
-
(2009)
Cancer Biother Radiopharm
, vol.24
, pp. 321-325
-
-
Minor, D.R.1
Chin, K.2
Kashani-Sabet, M.3
-
9
-
-
70350244517
-
Cytotoxic T-lymphocyte-associated antigen 4 antibody-induced colitis and its management with infliximab
-
PMID: 19104936
-
Johnston RL, Lutzky J, Chodhry A, Barkin JS. Cytotoxic T-lymphocyte-associated antigen 4 antibody-induced colitis and its management with infliximab. Dig Dis Sci 2009; 54: 2538-2540 [PMID: 19104936 DOI: 10.1007/s10620-008-0641-z]
-
(2009)
Dig Dis Sci
, vol.54
, pp. 2538-2540
-
-
Johnston, R.L.1
Lutzky, J.2
Chodhry, A.3
Barkin, J.S.4
-
10
-
-
84944261579
-
Immune-related adverse events, need for systemic immunosuppression, and effects on survival and time to treatment failure in patients with melanoma treated with ipilimumab at memorial sloan kettering cancer center
-
PMID: 26282644
-
Horvat TZ, Adel NG, Dang TO, Momtaz P, Postow MA, Callahan MK, Carvajal RD, Dickson MA, D'Angelo SP, Woo KM, Panageas KS, Wolchok JD, Chapman PB. Immune-Related Adverse Events, Need for Systemic Immunosuppression, and Effects on Survival and Time to Treatment Failure in Patients With Melanoma Treated With Ipilimumab at Memorial Sloan Kettering Cancer Center. J Clin Oncol 2015; 33: 3193-3198 [PMID: 26282644 DOI: 10.1200/JCO.2015.60.8448]
-
(2015)
J Clin Oncol
, vol.33
, pp. 3193-3198
-
-
Horvat, T.Z.1
Adel, N.G.2
Dang, T.O.3
Momtaz, P.4
Postow, M.A.5
Callahan, M.K.6
Carvajal, R.D.7
Dickson, M.A.8
D'Angelo, S.P.9
Woo, K.M.10
Panageas, K.S.11
Wolchok, J.D.12
Chapman, P.B.13
-
11
-
-
33744792341
-
Enterocolitis in patients with cancer after antibody blockade of cytotoxic T-lymphocyte-associated antigen 4
-
PMID: 16710025
-
Beck KE, Blansfield JA, Tran KQ, Feldman AL, Hughes MS, Royal RE, Kammula US, Topalian SL, Sherry RM, Kleiner D, Quezado M, Lowy I, Yellin M, Rosenberg SA, Yang JC. Enterocolitis in patients with cancer after antibody blockade of cytotoxic T-lymphocyte-associated antigen 4. J Clin Oncol 2006; 24: 2283-2289 [PMID: 16710025 DOI: 10.1200/JCO.2005.04.5716]
-
(2006)
J Clin Oncol
, vol.24
, pp. 2283-2289
-
-
Beck, K.E.1
Blansfield, J.A.2
Tran, K.Q.3
Feldman, A.L.4
Hughes, M.S.5
Royal, R.E.6
Kammula, U.S.7
Topalian, S.L.8
Sherry, R.M.9
Kleiner, D.10
Quezado, M.11
Lowy, I.12
Yellin, M.13
Rosenberg, S.A.14
Yang, J.C.15
-
12
-
-
27844458057
-
Tumor regression and autoimmunity in patients treated with cytotoxic T lymphocyteassociated antigen 4 blockade and interleukin 2: A phase I/II study
-
PMID: 16283570
-
Maker AV, Phan GQ, Attia P, Yang JC, Sherry RM, Topalian SL, Kammula US, Royal RE, Haworth LR, Levy C, Kleiner D, Mavroukakis SA, Yellin M, Rosenberg SA. Tumor regression and autoimmunity in patients treated with cytotoxic T lymphocyteassociated antigen 4 blockade and interleukin 2: a phase I/II study. Ann Surg Oncol 2005; 12: 1005-1016 [PMID: 16283570 DOI: 10.1245/ASO.2005.03.536]
-
(2005)
Ann Surg Oncol
, vol.12
, pp. 1005-1016
-
-
Maker, A.V.1
Phan, G.Q.2
Attia, P.3
Yang, J.C.4
Sherry, R.M.5
Topalian, S.L.6
Kammula, U.S.7
Royal, R.E.8
Haworth, L.R.9
Levy, C.10
Kleiner, D.11
Mavroukakis, S.A.12
Yellin, M.13
Rosenberg, S.A.14
-
13
-
-
78650428877
-
Blockade of cytotoxic T-lymphocyte antigen-4 by ipilimumab results in dysregulation of gastrointestinal immunity in patients with advanced melanoma
-
PMID: 21090563
-
Berman D, Parker SM, Siegel J, Chasalow SD, Weber J, Galbraith S, Targan SR, Wang HL. Blockade of cytotoxic T-lymphocyte antigen-4 by ipilimumab results in dysregulation of gastrointestinal immunity in patients with advanced melanoma. Cancer Immun 2010; 10: 11 [PMID: 21090563]
-
(2010)
Cancer Immun
, vol.10
, pp. 11
-
-
Berman, D.1
Parker, S.M.2
Siegel, J.3
Chasalow, S.D.4
Weber, J.5
Galbraith, S.6
Targan, S.R.7
Wang, H.L.8
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