메뉴 건너뛰기




Volumn 4, Issue , 2017, Pages 109-122

Is most published research really false?

Author keywords

False discoveries; Meta analysis; Reliability research; Replicability; Reproducibility; Science wise false discovery rate

Indexed keywords


EID: 85015257765     PISSN: 23268298     EISSN: 2326831X     Source Type: Journal    
DOI: 10.1146/annurev-statistics-060116-054104     Document Type: Review
Times cited : (45)

References (50)
  • 2
    • 85015187782 scopus 로고    scopus 로고
    • Changing our culture: Perspectives from young faculty
    • Allen G, Leek J. 2013. Changing our culture: Perspectives from young faculty. Amstat News, Dec. 1. http: //magazine.amstat.org/blog/2013/12/01/changing-our-culture/
    • (2013) Amstat News, Dec. , vol.1
    • Allen, G.1    Leek, J.2
  • 3
    • 80052526021 scopus 로고    scopus 로고
    • Public availability of published research data in high-impact journals
    • Alsheikh-Ali AA, Qureshi W, Al-Mallah MH, Ioannidis JP. 2011. Public availability of published research data in high-impact journals. PLOS ONE 6(9): E24357
    • (2011) PLOS ONE , vol.6 , Issue.9 , pp. e24357
    • Alsheikh-Ali, A.A.1    Qureshi, W.2    Al-Mallah, M.H.3    Ioannidis, J.P.4
  • 4
    • 85019292186 scopus 로고    scopus 로고
    • Science isn't broken
    • Aug. 19
    • Aschwanden C, King R. 2015. Science isn't broken. FiveThirtyEight Science, Aug. 19. http: //fivethirtyeight. com/features/science-isnt-broken/#part1
    • (2015) FiveThirtyEight Science
    • Aschwanden, C.1    King, R.2
  • 5
    • 77957106002 scopus 로고    scopus 로고
    • Disclose all data in publications
    • Baggerly K. 2010. Disclose all data in publications. Nature 467(7314): 401
    • (2010) Nature , vol.467 , Issue.7314 , pp. 401
    • Baggerly, K.1
  • 6
    • 77951163222 scopus 로고    scopus 로고
    • Deriving chemosensitivity from cell lines: Forensic bioinformatics and reproducible research in high-throughput biology
    • Baggerly KA, Coombes KR. 2009. Deriving chemosensitivity from cell lines: Forensic bioinformatics and reproducible research in high-throughput biology. Ann. Appl. Stat 3: 1309-34
    • (2009) Ann. Appl. Stat , vol.3 , pp. 1309-1334
    • Baggerly, K.A.1    Coombes, K.R.2
  • 7
    • 84859169880 scopus 로고    scopus 로고
    • Drug development: Raise standards for preclinical cancer research
    • Begley CG, Ellis LM. 2012. Drug development: Raise standards for preclinical cancer research. Nature 483(7391): 531-33
    • (2012) Nature , vol.483 , Issue.7391 , pp. 531-533
    • Begley, C.G.1    Ellis, L.M.2
  • 8
    • 0043041931 scopus 로고
    • WaveLab and reproducible research
    • ed. A Antoniadis, G Oppenheim, New York: Springer
    • Buckheit JB, Donoho DL. 1995. WaveLab and reproducible research. In Wavelets and Statistics, ed. A Antoniadis, G Oppenheim, pp. 55-81. New York: Springer
    • (1995) Wavelets and Statistics , pp. 55-81
    • Buckheit, J.B.1    Donoho, D.L.2
  • 9
    • 84876665206 scopus 로고    scopus 로고
    • Power failure: Why small sample size undermines the reliability of neuroscience
    • Button KS, Ioannidis JP, Mokrysz C, Nosek BA, Flint J, et al. 2013. Power failure: Why small sample size undermines the reliability of neuroscience. Nat. Rev. Neurosci. 14(5): 365-76
    • (2013) Nat. Rev. Neurosci. , vol.14 , Issue.5 , pp. 365-376
    • Button, K.S.1    Ioannidis, J.P.2    Mokrysz, C.3    Nosek, B.A.4    Flint, J.5
  • 10
    • 84893351797 scopus 로고    scopus 로고
    • NIH plans to enhance reproducibility
    • Collins FS, Tabak LA. 2014. NIH plans to enhance reproducibility. Nature 505(7485): 612
    • (2014) Nature , vol.505 , Issue.7485 , pp. 612
    • Collins, F.S.1    Tabak, L.A.2
  • 11
    • 84964495080 scopus 로고    scopus 로고
    • Peer review: Troubled from the start
    • Csiszar A. 2016. Peer review: Troubled from the start. Nat. News 532(7599): 306
    • (2016) Nat. News , vol.532 , Issue.7599 , pp. 306
    • Csiszar, A.1
  • 12
    • 84890544939 scopus 로고    scopus 로고
    • Discussion: Difficulties in making inferences about scientific truth from distributions of published p-values
    • Gelman A, O'Rourke K. 2014. Discussion: Difficulties in making inferences about scientific truth from distributions of published p-values. Biostatistics 15(1): 18-23
    • (2014) Biostatistics , vol.15 , Issue.1 , pp. 18-23
    • Gelman, A.1    O'Rourke, K.2
  • 13
    • 77955801615 scopus 로고    scopus 로고
    • Galaxy: A comprehensive approach for supporting accessible, reproducible, and transparent computational research in the life sciences
    • Goecks J, Nekrutenko A, Taylor J. 2010. Galaxy: A comprehensive approach for supporting accessible, reproducible, and transparent computational research in the life sciences. Genome Biol. 11(8): R86
    • (2010) Genome Biol. , vol.11 , Issue.8 , pp. R86
    • Goecks, J.1    Nekrutenko, A.2    Taylor, J.3
  • 15
    • 79955753954 scopus 로고    scopus 로고
    • Case studies in reproducibility
    • Hothorn T, Leisch F. 2011. Case studies in reproducibility. Brief. Bioinform. 12(3): 288-300
    • (2011) Brief. Bioinform. , vol.12 , Issue.3 , pp. 288-300
    • Hothorn, T.1    Leisch, F.2
  • 16
    • 22144431885 scopus 로고    scopus 로고
    • Contradicted and initially stronger effects in highly cited clinical research
    • Ioannidis JP. 2005a. Contradicted and initially stronger effects in highly cited clinical research. JAMA 294(2): 218-28
    • (2005) JAMA , vol.294 , Issue.2 , pp. 218-228
    • Ioannidis, J.P.1
  • 17
    • 33846563409 scopus 로고    scopus 로고
    • Why most published research findings are false
    • Ioannidis JP. 2005b.Why most published research findings are false. PLOS Med. 2(8): E124
    • (2005) PLOS Med. , vol.2 , Issue.8 , pp. e124
    • Ioannidis, J.P.1
  • 18
    • 84908350439 scopus 로고    scopus 로고
    • How to make more published research true
    • Ioannidis JP. 2014. How to make more published research true. PLOS Med. 11(10): E1001747
    • (2014) PLOS Med. , vol.11 , Issue.10 , pp. e1001747
    • Ioannidis, J.P.1
  • 19
    • 59149088407 scopus 로고    scopus 로고
    • Repeatability of published microarray gene expression analyses
    • Ioannidis JP, Allison DB, Ball CA, Coulibaly I, Cui X, et al. 2009. Repeatability of published microarray gene expression analyses. Nat. Genet. 41(2): 149-55
    • (2009) Nat. Genet. , vol.41 , Issue.2 , pp. 149-155
    • Ioannidis, J.P.1    Allison, D.B.2    Ball, C.A.3    Coulibaly, I.4    Cui, X.5
  • 20
    • 85015232057 scopus 로고    scopus 로고
    • People in positions of power that don't understand statistics are a big problem for genomics
    • Irizarry R. 2012. People in positions of power that don't understand statistics are a big problem for genomics. Simply Statistics Blog, Apr. 27. http: //simplystatistics.org/2012/04/27/people-in-positionsof- power-that-dont-understand/
    • (2012) Simply Statistics Blog, Apr. , vol.27
    • Irizarry, R.1
  • 21
    • 84890465866 scopus 로고    scopus 로고
    • An estimate of the science-wise false discovery rate and application to the top medical literature
    • Jager L, Leek J. 2014. An estimate of the science-wise false discovery rate and application to the top medical literature. Biostatistics 15(1): 1
    • (2014) Biostatistics , vol.15 , Issue.1 , pp. 1
    • Jager, L.1    Leek, J.2
  • 23
    • 35648976155 scopus 로고    scopus 로고
    • An introduction to the dataverse network as an infrastructure for data sharing
    • King G. 2007. An introduction to the dataverse network as an infrastructure for data sharing. Sociol. Methods Res. 36(2): 173-99
    • (2007) Sociol. Methods Res. , vol.36 , Issue.2 , pp. 173-199
    • King, G.1
  • 24
    • 84901716350 scopus 로고    scopus 로고
    • Investigating variation in replicability: A "Many Labs" replication project
    • Klein RA, Ratliff KA, Vianello M, Adams RB Jr., Bahník ? S, et al. 2014. Investigating variation in replicability: A "Many Labs" replication project. Soc. Psychol. 45: 142-52
    • (2014) Soc. Psychol. , vol.45 , pp. 142-152
    • Klein, R.A.1    Ratliff, K.A.2    Vianello, M.3    Adams, R.B.4    Bahník, S.5
  • 25
    • 85015165325 scopus 로고    scopus 로고
    • A summary of the evidence that most published research is false
    • Leek JT. 2013. A summary of the evidence that most published research is false. Simply Statistics Blog, Dec. 16. http: //simplystatistics.org/2013/12/16/a-summary-of-the-evidence-that-most-publishedresearch- is-false/
    • (2013) Simply Statistics Blog, Dec. , vol.16
    • Leek, J.T.1
  • 26
    • 85015251749 scopus 로고    scopus 로고
    • Why the three biggest positive contributions to reproducible research are the iPython Notebook, knitr, and Galaxy
    • Leek JT. 2014. Why the three biggest positive contributions to reproducible research are the iPython Notebook, knitr, and Galaxy. Simply Statistics Blog, Sep. 4. http: //simplystatistics.org/2014/09/04/whythe- three-biggest-positive-contributions-to-reproducible-research-are-the-ipython-notebookknitr- And-galaxy/
    • (2014) Simply Statistics Blog, Sep. , vol.4
    • Leek, J.T.1
  • 29
    • 84928801163 scopus 로고    scopus 로고
    • Statistics: P values are just the tip of the iceberg
    • Leek JT, Peng RD. 2015. Statistics: P values are just the tip of the iceberg. Nature 520(7549): 612
    • (2015) Nature , vol.520 , Issue.7549 , pp. 612
    • Leek, J.T.1    Peng, R.D.2
  • 31
    • 84877752060 scopus 로고    scopus 로고
    • A survey on data reproducibility in cancer research provides insights into our limited ability to translate findings from the laboratory to the clinic
    • Mobley A, Linder SK, Braeuer R, Ellis LM, Zwelling L. 2013. A survey on data reproducibility in cancer research provides insights into our limited ability to translate findings from the laboratory to the clinic. PLOS ONE 8(5): E63221
    • (2013) PLOS ONE , vol.8 , Issue.5 , pp. e63221
    • Mobley, A.1    Linder, S.K.2    Braeuer, R.3    Ellis, L.M.4    Zwelling, L.5
  • 32
    • 84865226981 scopus 로고    scopus 로고
    • Next-generation sequencing data interpretation: Enhancing reproducibility and accessibility
    • Nekrutenko A, Taylor J. 2012. Next-generation sequencing data interpretation: Enhancing reproducibility and accessibility. Nat. Rev. Genet. 13(9): 667-72
    • (2012) Nat. Rev. Genet. , vol.13 , Issue.9 , pp. 667-672
    • Nekrutenko, A.1    Taylor, J.2
  • 34
    • 84933567354 scopus 로고    scopus 로고
    • Promoting an open research culture: Author guidelines for journals could help to promote transparency, openness, and reproducibility
    • Nosek B, Alter G, Banks G, Borsboom D, Bowman S, et al. 2015. Promoting an open research culture: Author guidelines for journals could help to promote transparency, openness, and reproducibility. Science 348(6242): 1422
    • (2015) Science , vol.348 , Issue.6242 , pp. 1422
    • Nosek, B.1    Alter, G.2    Banks, G.3    Borsboom, D.4    Bowman, S.5
  • 36
    • 84940513037 scopus 로고    scopus 로고
    • Estimating the reproducibility of psychological science
    • Open Science Collaboration
    • Open Science Collaboration. 2015. Estimating the reproducibility of psychological science. Science 349: 6251
    • (2015) Science , vol.349 , pp. 6251
  • 37
    • 85015149719 scopus 로고    scopus 로고
    • A statistical definition for reproducibility and replicability
    • Patil P, Peng RD, Leek JT. 2016a. A statistical definition for reproducibility and replicability. Cold Spring Harb. Labs J. http: //biorxiv.org/content/early/2016/07/29/066803
    • (2016) Cold Spring Harb. Labs J.
    • Patil, P.1    Peng, R.D.2    Leek, J.T.3
  • 38
    • 84980042504 scopus 로고    scopus 로고
    • What should researchers expect when they replicate studies? A statistical view of replicability in psychological science
    • Patil P, Peng RD, Leek JT. 2016b.What should researchers expect when they replicate studies? A statistical view of replicability in psychological science. Perspect. Psychol. Sci. 11: 539-44
    • (2016) Perspect. Psychol. Sci. , vol.11 , pp. 539-544
    • Patil, P.1    Peng, R.D.2    Leek, J.T.3
  • 39
    • 70149102312 scopus 로고    scopus 로고
    • Reproducible research and biostatistics
    • Peng RD. 2009. Reproducible research and biostatistics. Biostatistics 10(3): 405-8
    • (2009) Biostatistics , vol.10 , Issue.3 , pp. 405-408
    • Peng, R.D.1
  • 40
    • 82755174123 scopus 로고    scopus 로고
    • Reproducible research in computational science
    • Peng RD. 2011. Reproducible research in computational science. Science 334(6060): 1226-27
    • (2011) Science , vol.334 , Issue.6060 , pp. 1226-1227
    • Peng, R.D.1
  • 42
    • 34247481878 scopus 로고    scopus 로고
    • IPython: A system for interactive scientific computing
    • Pérez F, Granger BE. 2007. IPython: A system for interactive scientific computing. Comput. Sci. Eng. 9(3): 21-29
    • (2007) Comput. Sci. Eng. , vol.9 , Issue.3 , pp. 21-29
    • Pérez, F.1    Granger, B.E.2
  • 43
    • 33750727368 scopus 로고    scopus 로고
    • Genomic signatures to guide the use of chemotherapeutics
    • Potti A, Dressman HK, Bild A, Riedel RF, Chan G, et al. 2006. Genomic signatures to guide the use of chemotherapeutics. Nat. Med. 12(11): 1294-300
    • (2006) Nat. Med. , vol.12 , Issue.11 , pp. 1294-1300
    • Potti, A.1    Dressman, H.K.2    Bild, A.3    Riedel, R.F.4    Chan, G.5
  • 44
    • 80055088241 scopus 로고    scopus 로고
    • Believe it or not: Howmuch can we rely on published data on potential drug targets?
    • Prinz F, Schlange T, Asadullah K. 2011. Believe it or not: Howmuch can we rely on published data on potential drug targets? Nat. Rev. Drug Discov. 10(9): 712-12
    • (2011) Nat. Rev. Drug Discov. , vol.10 , Issue.9 , pp. 712
    • Prinz, F.1    Schlange, T.2    Asadullah, K.3
  • 45
    • 77956104669 scopus 로고    scopus 로고
    • Growth in a time of debt
    • Rogoff K, Reinhart C. 2010. Growth in a time of debt. Am. Econ. Rev. 100(2): 573-8
    • (2010) Am. Econ. Rev. , vol.100 , Issue.2 , pp. 573-578
    • Rogoff, K.1    Reinhart, C.2
  • 46
    • 84879254020 scopus 로고    scopus 로고
    • Toward reproducible computational research: An empirical analysis of data and code policy adoption by journals
    • Stodden V, Guo P, Ma Z. 2013. Toward reproducible computational research: An empirical analysis of data and code policy adoption by journals. PLOS ONE 8(6): E67111
    • (2013) PLOS ONE , vol.8 , Issue.6 , pp. e67111
    • Stodden, V.1    Guo, P.2    Ma, Z.3
  • 48
    • 84976291730 scopus 로고    scopus 로고
    • The ASA's statement on p-values: Context, process, and purpose
    • Wasserstein RL, Lazar NA. 2016. The ASA's statement on p-values: Context, process, and purpose. Am. Stat. 70: 129-33
    • (2016) Am. Stat. , vol.70 , pp. 129-133
    • Wasserstein, R.L.1    Lazar, N.A.2
  • 49
    • 33750818722 scopus 로고    scopus 로고
    • Software carpentry
    • Wilson G. 2006. Software carpentry. Comput. Sci. Eng. 8: 66-69
    • (2006) Comput. Sci. Eng. , vol.8 , pp. 66-69
    • Wilson, G.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.