Unraveling the Gordian knot: Red blood cell storage lesion and transfusion outcomes

Blood Transfusion

Volumn 15, Issue 2, 2017, Pages 126-130

  Tzounakas, Vassilis L ^a   Kriebardis, Anastasios G ^b   Seghatchian, Jerard ^c   Papassideri, Issidora S ^a   Antonelou, Marianna H ^a  

^a NATIONAL AND KAPODISTRIAN UNIVERSITY OF ATHENS   (Greece)

^b UNIVERSITY OF WEST ATTICA   (Greece)

^c International Consultancy in Blood Components Quality Safety Improvement   (United Kingdom)

Author keywords

Clinical relevance; Donor recipient variation; Red blood cell storage lesion; Research opportunities; Transfusion outcome

Indexed keywords

COMPARATIVE STUDY; CONSENSUS; DEATH; ERYTHROCYTE PRESERVATION; ERYTHROCYTE TRANSFUSION; HUMAN; IN VITRO STUDY; IN VIVO STUDY; PATIENT CARE; RANDOMIZED CONTROLLED TRIAL (TOPIC); REVIEW; ADVERSE EFFECTS; BLOOD STORAGE; PROCEDURES; TIME FACTOR;

BLOOD PRESERVATION; ERYTHROCYTE TRANSFUSION; HUMANS; RANDOMIZED CONTROLLED TRIALS AS TOPIC; TIME FACTORS;

EID: 85015044940     PISSN: 17232007     EISSN: None     Source Type: Journal    
DOI: 10.2450/2017.0313-16     Document Type: Review

References (29)

1. Dern RJ, Gwinn RP, Wiorkowski JJ. Studies on the preservation of human blood. I. Variability in erythrocyte storage characteristics among healthy donors. J Lab Clin Med 1966; 67: 955-65.
2. Chasse M, McIntyre L, English SW, et al. Effect of blood donor characteristics on transfusion outcomes: a systematic review and meta-analysis. Transfus Med Rev 2016; 30: 69-80.
3. Kollman C, Howe CW, Anasetti C, et al. Donor characteristics as risk factors in recipients after transplantation of bone marrow from unrelated donors: the effect of donor age. Blood 2001; 98: 2043-51.
4. van 't Erve TJ, Wagner BA, Ryckman KK, et al. The concentration of glutathione in human erythrocytes is a heritable trait. Free Radic Biol Med 2013; 65: 742-9.
5. Tzounakas VL, Georgatzakou HT, Kriebardis AG, et al. Donor variation effect on red blood cell storage lesion: a multivariable, yet consistent, story. Transfusion 2016; 56: 1274-86.
6. Tzounakas VL, Georgatzakou HT, Kriebardis AG, et al. Uric acid variation among regular blood donors is indicative of red blood cell susceptibility to storage lesion markers: A new hypothesis tested. Transfusion 2015; 55: 2659-71.
7. Bawazir WM, Flatt JF, Wallis JP, et al. Familial pseudohyperkalemia in blood donors: a novel mutation with implications for transfusion practice. Transfusion 2014; 54: 3043-50.
8. Tzounakas VL, Kriebardis AG, Georgatzakou HT, et al. Glucose 6-phosphate dehydrogenase deficient subjects may be better "storers" than donors of red blood cells. Free Radic Biol Med 2016; 96: 152-65.
9. Rinalducci S, D'Amici GM, Blasi B, et al. Peroxiredoxin-2 as a candidate biomarker to test oxidative stress levels of stored red blood cells under blood bank conditions. Transfusion 2011; 51: 1439-49.
10. Tzounakas VL, Kriebardis AG, Papassideri IS, Antonelou MH. Donor-variation effect on red blood cell storage lesion: a close relationship emerges. Proteomics Clin Appl 2016; 10: 791-804.
11. Carson JL, Guyatt G, Heddle NM, et al. Clinical practice guidelines from the AABB: Red blood cell transfusion thresholds and storage. JAMA 2016; 316: 2025-35.
12. Paglia G, D'Alessandro A, Rolfsson O, et al. Biomarkers defining the metabolic age of red blood cells during cold storage. Blood 2016; 128: e43-50.
13. D'Alessandro A, Dzieciatkowska M, Hill RC, Hansen KC. Supernatant protein biomarkers of red blood cell storage hemolysis as determined through an absolute quantification proteomics technology. Transfusion 2016; 56: 1329-39.
14. Reisz JA, Wither MJ, Dzieciatkowska M, et al. Oxidative modifications of glyceraldehyde 3-phosphate dehydrogenase regulate metabolic reprogramming of stored red blood cells. Blood 2016; 128: e32-42.
15. Zimring JC, Smith N, Stowell SR, et al. Strain-specific red blood cell storage, metabolism, and eicosanoid generation in a mouse model. Transfusion 2014; 54: 137-48.
16. D'Alessandro A, Nemkov T, Yoshida T, et al. Citrate metabolism in red blood cells stored in additive solution-3. Transfusion 2016; DOI 10.1111/trf.13892.
17. Antonelou MH, Seghatchian J. Update on extracellular vesicles inside red blood cell storage units: adjust the sails closer to the new wind. Transfus Apher Sci 2016; 55: 92-104.
18. Mittag D, Sran A, Chan KS, et al. Stored red blood cell susceptibility to in vitro transfusion-associated stress conditions is higher after longer storage and increased by storage in saline-adenine-glucose-mannitol compared to AS-1. Transfusion 2015; 55: 2197-206.
19. de Wolski K, Fu X, Dumont LJ, et al. Metabolic pathways that correlate with post-transfusion circulation of stored murine red blood cells. Haematologica 2016; 101: 578-86.
20. Zimring JC, Spitalnik SL. Scientific advances: fallacy of perfection harms peer review. Nature 2016; 537: 34.
21. National Heart, Lung and Blood Institute, REDS-III Phase 2 Studies. Available at: https://reds-iii.rti.org/ResearchStudies/Phase2Studies.aspx. Accessed on 23/12/2016.
22. Lacroix J, Hebert PC, Fergusson DA, et al. Age of transfused blood in critically ill adults. N Engl J Med 2015; 372: 1410-8.
23. Heddle NM, Cook RJ, Arnold DM, et al. Effect of short-term vs. long-term blood storage on mortality after transfusion. N Engl J Med 2016; 375: 1937-45.
24. Francis RO, Jhang JS, Pham HP, et al. Glucose-6-phosphate dehydrogenase deficiency in transfusion medicine: the unknown risks. Vox Sang 2013; 105: 271-82.
25. Bosman GJ. Survival of red blood cells after transfusion: processes and consequences. Front Physiol 2013; 4: 376.
26. Glynn SA, Klein HG, Ness PM. The red blood cell storage lesion: the end of the beginning. Transfusion 2016; 56: 1462-8.
27. Petrik J, Seghatchian J. Big things from small packages: the multifaceted roles of extracellular vesicles in the components quality, therapy and infection. Transfus Apher Sci 2016; 55: 4-8.
28. Chasse M, Tinmouth A, English SW, et al. Association of blood donor age and sex with recipient survival after red blood cell transfusion. JAMA Intern Med 2016; 176: 1307-14.
29. L'Acqua C, Bandyopadhyay S, Francis RO, et al. Red blood cell transfusion is associated with increased hemolysis and an acute phase response in a subset of critically ill children. Am J Hematol 2015; 90: 915-20.