A mechanistic evaluation of the traditional uses of Nepeta ruderalis in gastrointestinal and airway disorders

Pharmaceutical Biology

Volumn 55, Issue 1, 2017, Pages 1017-1021

  Mahmood, Hassan ^a   Chaudhry, Mueen Ahmad ^a,b   Masood, Zeeshan ^a   Saeed, Muhammad Asad ^a   Adnan, Sherjeel ^a  

^a UNIVERSITY OF LAHORE   (Pakistan)

^b UNIVERSITY OF SARGODHA   (Pakistan)

Author keywords

Antidiarrhoeal; Bronchorelaxant; Calcium channel blocking activity; Spasmolytic

Indexed keywords

ANTIDIARRHEAL AGENT; CARBACHOL; LOPERAMIDE; NEPETA RUDERALIS EXTRACT; PLANT EXTRACT; SPASMOLYTIC AGENT; UNCLASSIFIED DRUG; VERAPAMIL; CALCIUM; CALCIUM CHANNEL BLOCKING AGENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIDIARRHEAL ACTIVITY; ARTICLE; BRONCHORELAXANT ACTIVITY; CASTOR OIL-INDUCED DIARRHEA; CONTROLLED STUDY; DRUG ACTIVITY; EC50; IN VITRO STUDY; IN VIVO STUDY; JEJUNUM; MOUSE; NONHUMAN; RESPIRATORY TRACT DISEASE; SPASMOLYTIC ACTIVITY; TRACHEA; TRADITIONAL MEDICINE; ANIMAL; DRUG EFFECTS; METABOLISM; NEPETA; PHYSIOLOGY; PHYTOTHERAPY; RABBIT;

ANIMALS; ANTIDIARRHEALS; CALCIUM; CALCIUM CHANNEL BLOCKERS; CARBACHOL; JEJUNUM; MICE; NEPETA; PHYTOTHERAPY; PLANT EXTRACTS; RABBITS; TRACHEA;

EID: 85014912250     PISSN: 13880209     EISSN: 17445116     Source Type: Journal    
DOI: 10.1080/13880209.2017.1285325     Document Type: Article

References (29)

1. Ahmad VU, Bano S, Mohammad FV. 1985. Nepehinol - a new triterpene from Nepeta hindostana. Planta Med. 51:521-523.
2. Ahmad VU, Noorwala M, Mohammad FV, Shah MG, Parvez A. 1993. Nepehinal: a new triterpenoidal aldehyde from Nepeta hindostana. Planta Med. 59:366-368.
3. Ahmed T. 1992. Calcium antagonists: potential for asthma therapy. Choices Respir Manage. 22:41-43.
4. Awan MH. 1960. Kitab ul Mafroodat. Lahore, Pakistan: Sheikh Ghulam Ali and Sons (pvt) Limited.
5. Berridge MJ, Bootman MD, Roderick HL. 2003. Calcium signalling: dynamics, homeostasis and remodelling. Nat Rev Mol Cell Biol. 4:517-529.
6. Bolton TB. 1979. Mechanisms of action of transmitters and other substances on smooth muscle. Physiol Rev. 59:606-718.
7. Burks TF. 1987. Actions of drugs on gastrointestinal motility. In: Johnson LR, editor. Physiology of the Gastrointestinal Tract. New York: Raven Press; p. 723-743.
8. Chaudhary MA, Imran I, Bashir S, Mehmood MH, Rehman NU, Gilani AH. 2012. Evaluation of gut modulatory and bronchodilator activities of Amaranthus spinosus Linn. BMC Complement Altern Med. 12:166
9. Clark JD, Baldwin RL, Bayne KA, Brown MJ, Gebhart GF, Gonder JC, Gwathmey JK, Keeling ME, Kohn DF, Robb JW, Smith OA. 1996. Guide for the care and use of laboratory animals. Washington, DC, USA: Institute of Laboratory Animal Resources, National Research Council.
10. Janbaz KH, Hassan W, Mehmood MH, Gilani AH. 2015. Antidiarrheal, antispasmodic and bronchodilator activities of Pistacia integerrima are mediated through dual inhibition of muscarinic receptors and Ca+2 influx. Sci Tech Dev. 34:52-59.
11. Janbaz KH, Latif MF, Saqib F, Imran I, Zia-Ul-Haq M, De Feo V. 2013. Pharmacological effects of Lactuca serriola L. in experimental model of gastrointestinal, respiratory, and vascular ailments. Evid Based Complement Alternat Med. 304394.
12. Kew. 2014. An online resource for the world’s plants [Internet]. c Board of Trustees of the Royal Botanic Gardens, Kew; [cited 2016 Jan 16]. Available from: http://wfo.kew.org/.
13. Khan A, Gilani AH. 2009. Antispasmodic and bronchodilator activities of Artemisia vulgaris are mediated through dual blockade of muscarinic receptors and calcium influx. J Ethnopharmacol. 126:480-486.
14. Khan M, Shah AJ, Gilani AH. 2013. Antidiarrheal and antispasmodic activities of Vitex negundo are mediated through calcium channel blockade. Bangladesh J Pharmacol. 8:317-322.
15. Khare CP. 2007. Indian medicinal plants: an illustrated dictionary. New Delhi, India: Springer.
16. Koche D. 2010. Trace element analysis and vitamins from an Indian medicinal plant Nepeta hindostana (ROTH) Haines. Int J Pharm Pharm Sci. 3:53-54.
17. Mehmood MH, Aziz N, Ghayur MN, Gilani AH. 2011a. Pharmacological basis for the medicinal use of Psyllium husk (Ispaghula) in constipation and diarrhea. Dig Dis Sci. 56:1460-1471.
18. Mehmood MH, Hasan SS, Gilani AH. 2011b. The antidiarrheal and spasmolytic activities of Phyllanthus emblica are mediated through dual blockade of muscarinic receptors and Ca2+ channels. J Ethnopharmacol. 133:856-865.
19. Michael T, Hoffman BB. 2011. Treatment of myocardial ischemia and hypertension. In: Brunton LL, Chabner BA, Knollmann BC, ed. Goodman and Gilman’s The Pharmacological Basis of Therapeutics. China: McGraw-Hill Medical; p. 745-788.
20. Mushtaq S, Chaudhry MA, Rahman HMA. 2015. Calcium channels blocked activity: providing the basis for medicinal use of Abies pindrow in diarrhea and bronchitis. Bangladesh J Pharmacol. 10:430-435.
21. Nadkarni KM. 1996. Indian Materia Medica with Ayurvedic, Unani-tibbi, Siddha, Allopathic, Homeopathic, Naturopathic & Home Remedies, appendices & indexes. Bombay, India: Popular Prakashan.
22. Naz SB, Chaudhary MA, Ul RMS. 2016. Dual receptor blocker mechanism arbitrates smooth muscle relaxant effect of Polypodium vulgare Linn. Bangladesh J Pharmacol. 11:414-420.
23. Pandey AK, Mohan M, Singh P, Tripathi NN. 2015. Chemical composition, antioxidant and antimicrobial activities of the essential oil of Nepeta hindostana (Roth) Haines from India. Rec Nat Prod. 9:224-233.
24. Quattrocchi U. 2012. CRC world dictionary of medicinal and poisonous plants: common names, scientific names, eponyms, synonyms, and etymology. Florida, USA: CRC Press.
25. Qureshi HM, Omer OM, Ashraf M, Bukhsh A, Chaudhry MA, Imran MS. 2015. Evaluation of antihistaminic and anticholinergic activities of Murraya koenigii Linn. Pak Vet J. 35:242-244.
26. Rehman NU, Khan AU, Alkharfy KM, Gilani AH. 2012. Pharmacological basis for the medicinal use of Lepidium sativum in airways disorders. Evid Based Complement Alternat Med. 596524.
27. Ur-Rahaman MS, Chaudhary MA, Ahmad B, Alamgeer A. 2013. Rationalization of traditional uses of Berberis lycium in gastrointestinal disorders. Br J Med Med Res. 3:868-879.
28. Van Rossum JM. 1963. Cumulative dose-response curves. II. Technique for the making of dose-response curves in isolated organs and the evaluation of drug parameters. Arch Int Pharmacodyn Ther. 143:299-330.
29. Williamson EM, Okpako DT, Evans FJ. 1998. Selection, preparation and pharmacological evaluation of plant material. Chichester, West Sussex: John Wiley & Sons.