-
1
-
-
65649089528
-
Promising antituberculosis activity of the oxazolidinone PNU-100480 relative to that of linezolid in a murine model
-
Williams K N, Stover C K, Zhu T, et al. Promising antituberculosis activity of the oxazolidinone PNU-100480 relative to that of linezolid in a murine model. Antimicrob Agents Chemother 2009; 53: 1314-1319.
-
(2009)
Antimicrob Agents Chemother
, vol.53
, pp. 1314-1319
-
-
Williams, K.N.1
Stover, C.K.2
Zhu, T.3
-
2
-
-
84903888878
-
Analysis of combination drug therapy to develop regimens with shortened duration of treatment for tuberculosis
-
Drusano G L, Neely M, Van Guilder M, et al. Analysis of combination drug therapy to develop regimens with shortened duration of treatment for tuberculosis. PLOS ONE 2014; 9: e101311.
-
(2014)
PLOS ONE
, vol.9
-
-
Drusano, G.L.1
Neely, M.2
Van Guilder, M.3
-
3
-
-
84915818775
-
PET/CT imaging reveals a therapeutic response to oxazolidinones in macaques and humans with tuberculosis
-
Coleman M T, Chen RY, Lee M, et al. PET/CT imaging reveals a therapeutic response to oxazolidinones in macaques and humans with tuberculosis. Sci Transl Med 2014; 6: 265ra167.
-
(2014)
Sci Transl Med
, vol.6
, pp. 265ra167
-
-
Coleman, M.T.1
Chen, R.Y.2
Lee, M.3
-
4
-
-
56749180450
-
Early and extended early bactericidal activity of linezolid in pulmonary tuberculosis
-
Dietze R, Hadad D J, McGee B, et al. Early and extended early bactericidal activity of linezolid in pulmonary tuberculosis. Am J Respir Crit Care Med 2008: 178: 1180-1185.
-
(2008)
Am J Respir Crit Care Med
, vol.178
, pp. 1180-1185
-
-
Dietze, R.1
Hadad, D.J.2
McGee, B.3
-
5
-
-
84867614599
-
Linezolid for treatment of chronic extensively drug-resistant tuberculosis
-
Lee M, Lee J, Carroll M W, et al. Linezolid for treatment of chronic extensively drug-resistant tuberculosis. N Engl J Med 2012; 367: 1508-1518.
-
(2012)
N Engl J Med
, vol.367
, pp. 1508-1518
-
-
Lee, M.1
Lee, J.2
Carroll, M.W.3
-
6
-
-
84937027327
-
Linezolid for XDR-TB - Final study outcomes
-
Lee M, Cho S N, Barry C E, Song T, Kim Y, Jeong I. Linezolid for XDR-TB - final study outcomes. N Engl J Med 2015; 373: 290-291.
-
(2015)
N Engl J Med
, vol.373
, pp. 290-291
-
-
Lee, M.1
Cho, S.N.2
Barry, C.E.3
Song, T.4
Kim, Y.5
Jeong, I.6
-
7
-
-
84863177484
-
Linezolid in the treatment of MDR-TB: A retrospective clinical study
-
Xu H B, Jiang R H, Li L, Xiao H P. Linezolid in the treatment of MDR-TB: a retrospective clinical study. Int J Tuberc Lung Dis 2012; 16: 358-363.
-
(2012)
Int J Tuberc Lung Dis
, vol.16
, pp. 358-363
-
-
Xu, H.B.1
Jiang, R.H.2
Li, L.3
Xiao, H.P.4
-
8
-
-
84858657770
-
Linezolid for the treatment of complicated drug-resistant tuberculosis: A systematic review and meta-analysis
-
Cox H, Ford N. Linezolid for the treatment of complicated drug-resistant tuberculosis: a systematic review and meta-analysis. Int J Tuberc Lung Dis 2012; 16: 447-454.
-
(2012)
Int J Tuberc Lung Dis
, vol.16
, pp. 447-454
-
-
Cox, H.1
Ford, N.2
-
9
-
-
34548495074
-
Back to the future: Using aminoglycosides again and how to dose them optimally
-
Drusano G L, Ambrose P G, Bhavnani S M, Bertino J S, Nafziger A N, Louie A. Back to the future: using aminoglycosides again and how to dose them optimally. Clin Infect Dis 2007; 45: 753-760.
-
(2007)
Clin Infect Dis
, vol.45
, pp. 753-760
-
-
Drusano, G.L.1
Ambrose, P.G.2
Bhavnani, S.M.3
Bertino, J.S.4
Nafziger, A.N.5
Louie, A.6
-
10
-
-
84960366090
-
Evaluation of daptomycin exposure and efficacy and safety endpoints to support risk-versus-benefit considerations
-
Bhavnani S M, Ambrose P G, Hammel J P, Rubino C M, Drusano G L. Evaluation of daptomycin exposure and efficacy and safety endpoints to support risk-versus-benefit considerations. Antimicrob Agents Chemother 2015; 60: 1600-1607.
-
(2015)
Antimicrob Agents Chemother
, vol.60
, pp. 1600-1607
-
-
Bhavnani, S.M.1
Ambrose, P.G.2
Hammel, J.P.3
Rubino, C.M.4
Drusano, G.L.5
-
11
-
-
85048344906
-
Regimen development with novel chemical entities
-
Cape Town, South Africa, 2-6 December Session N. 00121. Symposium 45: Finding better treatments sooner: innovations in clinical trials for new regimens beyond 2015
-
th World Conference on Lung Health of the International Union Against Tuberculosis and Lung Disease, Cape Town, South Africa, 2-6 December 2015. Session N. 00121. Symposium 45: Finding better treatments sooner: innovations in clinical trials for new regimens beyond 2015.
-
(2015)
th World Conference on Lung Health of the International Union Against Tuberculosis and Lung Disease
-
-
Mendel, C.1
-
12
-
-
84952802606
-
Preclinical evaluations to identify optimal linezolid regimens for tuberculosis therapy
-
Brown A N, Drusano G L, Adams J R, et al. Preclinical evaluations to identify optimal linezolid regimens for tuberculosis therapy. MBio 2015; 6: e01741-15.
-
(2015)
MBio
, vol.6
, pp. e01741-e01815
-
-
Brown, A.N.1
Drusano, G.L.2
Adams, J.R.3
-
13
-
-
84901289434
-
Population pharmacokinetic/pharmacodynamic analysis of the bactericidal activities of sutezolid (PNU-100480) and its major metabolite against intracellular mycobacterium tuberculosis in ex vivo whole-blood cultures of patients with pulmonary tuberculosis
-
Zhu T, Friedrich S O, Diacon, Wallis R S. Population pharmacokinetic/pharmacodynamic analysis of the bactericidal activities of sutezolid (PNU-100480) and its major metabolite against intracellular Mycobacterium tuberculosis in ex vivo whole-blood cultures of patients with pulmonary tuberculosis. Antimicrob Agents Chemother 2014; 58: 3306-3311.
-
(2014)
Antimicrob Agents Chemother
, vol.58
, pp. 3306-3311
-
-
Zhu, T.1
Friedrich, S.O.2
Diacon3
Wallis, R.S.4
-
14
-
-
84455173006
-
Differential effects of linezolid and ciprofloxacin on toxin production by bacillus anthracis in an in vitro pharmacodynamic system
-
Louie A, VanScoy B D, Heine H S, et al. Differential effects of linezolid and ciprofloxacin on toxin production by Bacillus anthracis in an in vitro pharmacodynamic system. Antimicrob Agents Chemother 2012; 56: 513-517.
-
(2012)
Antimicrob Agents Chemother
, vol.56
, pp. 513-517
-
-
Louie, A.1
VanScoy, B.D.2
Heine, H.S.3
-
15
-
-
46249110625
-
Use of an in vitro pharmacodynamic model to derive a linezolid regimen that optimizes bacterial kill and prevents emergence of resistance in bacillus anthracis
-
Louie A, Heine H S, Kim K, et al. Use of an in vitro pharmacodynamic model to derive a linezolid regimen that optimizes bacterial kill and prevents emergence of resistance in Bacillus anthracis. Antimicrob Agents Chemother 2008; 52: 2486-2496.
-
(2008)
Antimicrob Agents Chemother
, vol.52
, pp. 2486-2496
-
-
Louie, A.1
Heine, H.S.2
Kim, K.3
-
16
-
-
84994655873
-
Linezolid for babies and toddlers with disseminated tuberculosis: First steps
-
(in press)
-
Deshpande D, Srivastava S, Pasipanodya P, et al. Linezolid for babies and toddlers with disseminated tuberculosis: first steps. Clin Infect Dis 2016 (in press).
-
(2016)
Clin Infect Dis
-
-
Deshpande, D.1
Srivastava, S.2
Pasipanodya, P.3
-
17
-
-
0242287626
-
Clinical pharmacodynamics of linezolid in seriously ill patients treated in a compassionate use programme
-
Rayner C R, Forrest A, Meagher A K, Birmingham M C, Schentag J J. Clinical pharmacodynamics of linezolid in seriously ill patients treated in a compassionate use programme. Clin Pharmacokinet 2003; 42: 1411-1423.
-
(2003)
Clin Pharmacokinet
, vol.42
, pp. 1411-1423
-
-
Rayner, C.R.1
Forrest, A.2
Meagher, A.K.3
Birmingham, M.C.4
Schentag, J.J.5
-
18
-
-
84903196128
-
Pharmacokinetic and pharmacodynamic evaluation of AZD5847 in a mouse model of tuberculosis
-
Balasubramanian V, Solapure S, Shandil R, et al. Pharmacokinetic and pharmacodynamic evaluation of AZD5847 in a mouse model of tuberculosis. Antimicrob Agents Chemother 2014; 58: 4185-4190.
-
(2014)
Antimicrob Agents Chemother
, vol.58
, pp. 4185-4190
-
-
Balasubramanian, V.1
Solapure, S.2
Shandil, R.3
-
19
-
-
67650730258
-
Daily 300 mg dose of linezolid for the treatment of intractable multidrug-resistant and extensively drug-resistant tuberculosis
-
Koh W J, Kwon O J, Gwak H, et al. Daily 300 mg dose of linezolid for the treatment of intractable multidrug-resistant and extensively drug-resistant tuberculosis. J Antimicrob Chemother 2009; 64: 388-391.
-
(2009)
J Antimicrob Chemother
, vol.64
, pp. 388-391
-
-
Koh, W.J.1
Kwon, O.J.2
Gwak, H.3
-
20
-
-
77954467776
-
Comparison of the pharmacokinetics of two dosage regimens of linezolid in multidrug-resistant and extensively drug-resistant tuberculosis patients
-
Alffenaar J W, van AR, Harmelink I M, et al. Comparison of the pharmacokinetics of two dosage regimens of linezolid in multidrug-resistant and extensively drug-resistant tuberculosis patients. Clin Pharmacokinet 2010; 49: 559-565.
-
(2010)
Clin Pharmacokinet
, vol.49
, pp. 559-565
-
-
Alffenaar, J.W.1
Van, A.R.2
Harmelink, I.M.3
-
21
-
-
70349119890
-
Population pharmacokinetics of linezolid in adults with pulmonary tuberculosis
-
McGee B, Dietze R, Hadad D J, et al. Population pharmacokinetics of linezolid in adults with pulmonary tuberculosis. Antimicrob Agents Chemother 2009; 53: 3981-3984.
-
(2009)
Antimicrob Agents Chemother
, vol.53
, pp. 3981-3984
-
-
McGee, B.1
Dietze, R.2
Hadad, D.J.3
-
22
-
-
84958881453
-
Linezolid trough concentrations correlate with mitochondrial toxicity-related adverse events in the treatment of chronic extensively drug-resistant tuberculosis
-
Song T, Lee M, Jeon H S, et al. Linezolid trough concentrations correlate with mitochondrial toxicity-related adverse events in the treatment of chronic extensively drug-resistant tuberculosis. EBio Med 2015; 2: 1627-1633.
-
(2015)
EBio Med
, vol.2
, pp. 1627-1633
-
-
Song, T.1
Lee, M.2
Jeon, H.S.3
-
23
-
-
84872478931
-
Linezolid for extensively drug-resistant tuberculosis
-
Cattaneo D, Orlando G, Cordier L. Linezolid for extensively drug-resistant tuberculosis. N Engl J Med 2013; 368: 291.
-
(2013)
N Engl J Med
, vol.368
, pp. 291
-
-
Cattaneo, D.1
Orlando, G.2
Cordier, L.3
-
24
-
-
85027943994
-
Analysis of thrombocytopenic effects and population pharmacokinetics of linezolid: A dosage strategy according to the trough concentration target and renal function in adult patients
-
Matsumoto K, Shigemi A, Takeshita A, et al. Analysis of thrombocytopenic effects and population pharmacokinetics of linezolid: a dosage strategy according to the trough concentration target and renal function in adult patients. Int J Antimicrob Agents 2014; 44: 242-247.
-
(2014)
Int J Antimicrob Agents
, vol.44
, pp. 242-247
-
-
Matsumoto, K.1
Shigemi, A.2
Takeshita, A.3
-
25
-
-
84879026253
-
Can intermittent dosing optimize prolonged linezolid treatment of difficult multidrug-resistant tuberculosis?
-
Chang K C, Yew W W, Cheung S W, et al. Can intermittent dosing optimize prolonged linezolid treatment of difficult multidrug-resistant tuberculosis? Antimicrob Agents Chemother 2013; 57: 3445-3449.
-
(2013)
Antimicrob Agents Chemother
, vol.57
, pp. 3445-3449
-
-
Chang, K.C.1
Yew, W.W.2
Cheung, S.W.3
-
26
-
-
84957877941
-
Contribution of oxazolidinones to the efficacy of novel regimens containing bedaquiline and Pretomanid in a mouse model of tuberculosis
-
Tasneen R, Betoudji F, Tyagi S, et al. Contribution of oxazolidinones to the efficacy of novel regimens containing bedaquiline and pretomanid in a mouse model of tuberculosis. Antimicrob Agents Chemother 2015; 60: 270-277.
-
(2015)
Antimicrob Agents Chemother
, vol.60
, pp. 270-277
-
-
Tasneen, R.1
Betoudji, F.2
Tyagi, S.3
-
27
-
-
84896989728
-
Clinical population pharmacokinetics and toxicodynamics of linezolid
-
Boak L M, Rayner C R, GraysonM L, et al. Clinical population pharmacokinetics and toxicodynamics of linezolid. Antimicrob Agents Chemother 2014; 58: 2334-2343.
-
(2014)
Antimicrob Agents Chemother
, vol.58
, pp. 2334-2343
-
-
Boak, L.M.1
Rayner, C.R.2
Grayson, M.L.3
|