Haemolysis in G6PD Heterozygous Females Treated with Primaquine for Plasmodium vivax Malaria: A Nested Cohort in a Trial of Radical Curative Regimens

PLoS Medicine

Volumn 14, Issue 2, 2017, Pages

  Chu, Cindy S ^a,b   Bancone, Germana ^a,b   Moore, Kerryn A ^c,d   Win, Htun Htun ^a   Thitipanawan, Niramon ^a   Po, Christina ^a   Chowwiwat, Nongnud ^a   Raksapraidee, Rattanaporn ^a   Wilairisak, Pornpimon ^a   Phyo, Aung Pyae ^a   Keereecharoen, Lily ^a   Proux, Stéphane ^a   Charunwatthana, Prakaykaew ^e,f   Nosten, François ^a,b   White, Nicholas J ^b,e  

^a SHOKLO MALARIA RESEARCH UNIT   (Thailand)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c MACFARLANE BURNET INSTITUTE FOR MEDICAL RESEARCH AND PUBLIC HEALTH   (Australia)

^d UNIVERSITY OF MELBOURNE   (Australia)

^e MAHIDOL OXFORD TROPICAL MEDICINE RESEARCH UNIT   (Thailand)

^f MAHIDOL UNIVERSITY   (Thailand)

Author keywords

[No Author keywords available]

Indexed keywords

CHLOROQUINE; DIHYDROARTEMISININ PLUS PIPERAQUINE; GLUCOSE 6 PHOSPHATE DEHYDROGENASE; PRIMAQUINE; ANTIMALARIAL AGENT;

ABDOMINAL PAIN; ADOLESCENT; ADULT; ARTICLE; BACKACHE; BLOOD TRANSFUSION; CHILD; COHORT ANALYSIS; CONTROLLED STUDY; DIZZINESS; DRUG DOSE COMPARISON; DRUG MEGADOSE; ENZYME ACTIVITY; FATIGUE; FEMALE; GENOTYPING TECHNIQUE; HEADACHE; HEART PALPITATION; HEMATOCRIT; HEMOLYSIS; HETEROZYGOTE; HUMAN; MAJOR CLINICAL STUDY; MYALGIA; PLASMODIUM VIVAX MALARIA; PRESCHOOL CHILD; RANDOMIZED CONTROLLED TRIAL; SCHOOL CHILD; TREATMENT OUTCOME; DOSE RESPONSE; DRUG EFFECT; GENETICS; GENOTYPE; MIDDLE AGED; MYANMAR; PARASITOLOGY; PHENOTYPE; PHYSIOLOGY; PLASMODIUM VIVAX; THAILAND; YOUNG ADULT;

ADOLESCENT; ADULT; ANTIMALARIALS; CHILD; CHILD, PRESCHOOL; COHORT STUDIES; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; GENOTYPE; GLUCOSEPHOSPHATE DEHYDROGENASE; HEMATOCRIT; HEMOLYSIS; HUMANS; MALARIA, VIVAX; MIDDLE AGED; MYANMAR; PHENOTYPE; PLASMODIUM VIVAX; PRIMAQUINE; THAILAND; YOUNG ADULT;

EID: 85014495886     PISSN: 15491277     EISSN: 15491676     Source Type: Journal    
DOI: 10.1371/journal.pmed.1002224     Document Type: Article

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