메뉴 건너뛰기




Volumn 19, Issue 8, 2017, Pages 931-944

Diffuse low-grade glioma: a review on the new molecular classification, natural history and current management strategies

Author keywords

Astrocytoma; Chemotherapy; Low grade glioma; Natural history; Oligodendroglioma; Radiotherapy; Supratotal resection; WHO glioma classification

Indexed keywords

ASTROCYTOMA; CANCER ADJUVANT THERAPY; CANCER CHEMOTHERAPY; CANCER INFILTRATION; CELL MIGRATION; CHEMORADIOTHERAPY; GENE MUTATION; GLIOMA; HUMAN; LIFE EXPECTANCY; OLIGODENDROGLIOMA; OVERALL SURVIVAL; PROGNOSTIC ASSESSMENT; QUALITY OF LIFE; REOPERATION; REVIEW; TUMOR CLASSIFICATION; BRAIN TUMOR; CANCER GRADING; CLASSIFICATION; DISEASE MANAGEMENT; MULTIMODALITY CANCER THERAPY; PATHOLOGY;

EID: 85014086698     PISSN: 1699048X     EISSN: 16993055     Source Type: Journal    
DOI: 10.1007/s12094-017-1631-4     Document Type: Review
Times cited : (103)

References (87)
  • 3
    • 83655190562 scopus 로고    scopus 로고
    • Aspectos controvertidos en el manejo de gliomas hemisféricos OMS grado III: revision de la bibliografía reciente
    • PID: 22127662
    • Rueda E, Sierra M, Infante J, Berciano J, Vázquez-Barquero A, Ciordia R, et al. Aspectos controvertidos en el manejo de gliomas hemisféricos OMS grado III: revision de la bibliografía reciente. Rev Neurol. 2011;53:747–57.
    • (2011) Rev Neurol. , vol.53 , pp. 747-757
    • Rueda, E.1    Sierra, M.2    Infante, J.3    Berciano, J.4    Vázquez-Barquero, A.5    Ciordia, R.6
  • 4
    • 84987608285 scopus 로고    scopus 로고
    • New concepts in the management of diffuse low-grade glioma: proposal of a multistage and individualized therapeutic approach
    • PID: 25087230
    • Duffau H, Taillandier L. New concepts in the management of diffuse low-grade glioma: proposal of a multistage and individualized therapeutic approach. Neuro Oncol. 2015;17:332–42.
    • (2015) Neuro Oncol. , vol.17 , pp. 332-342
    • Duffau, H.1    Taillandier, L.2
  • 6
    • 85027948565 scopus 로고    scopus 로고
    • International Society Of Neuropathology-Haarlem consensus guidelines for nervous system tumor classification and grading
    • PID: 24990071
    • Louis DN, Perry A, Burger P, Ellison DW, Reifenberger G, von Deimling A, et al. International Society Of Neuropathology-Haarlem consensus guidelines for nervous system tumor classification and grading. Brain Pathol. 2014;24:429–35.
    • (2014) Brain Pathol , vol.24 , pp. 429-435
    • Louis, D.N.1    Perry, A.2    Burger, P.3    Ellison, D.W.4    Reifenberger, G.5    von Deimling, A.6
  • 8
    • 65549124836 scopus 로고    scopus 로고
    • Re-operation is a safe and effective therapeutic strategy in recurrent WHO grade II gliomas within eloquent areas
    • discussion 436
    • Martino J, Taillandier L, Moritz-Gasser S, Gatignol P, Duffau H. Re-operation is a safe and effective therapeutic strategy in recurrent WHO grade II gliomas within eloquent areas. Acta Neurochir (Wien). 2009;151:427–36 (discussion 436).
    • (2009) Acta Neurochir (Wien) , vol.151 , pp. 427-436
    • Martino, J.1    Taillandier, L.2    Moritz-Gasser, S.3    Gatignol, P.4    Duffau, H.5
  • 9
    • 36849078285 scopus 로고    scopus 로고
    • Contribution of cortical and subcortical electrostimulation in brain glioma surgery: methodological and functional considerations
    • COI: 1:STN:280:DC%2BD2sjks1Cnsw%3D%3D, PID: 18083492
    • Duffau H. Contribution of cortical and subcortical electrostimulation in brain glioma surgery: methodological and functional considerations. Neurophysiol Clin. 2007;37:373–82.
    • (2007) Neurophysiol Clin , vol.37 , pp. 373-382
    • Duffau, H.1
  • 10
    • 22144479816 scopus 로고    scopus 로고
    • Lessons from brain mapping in surgery for low-grade glioma: insights into associations between tumour and brain plasticity
    • PID: 16033690
    • Duffau H. Lessons from brain mapping in surgery for low-grade glioma: insights into associations between tumour and brain plasticity. Lancet Neurol. 2005;4:476–86.
    • (2005) Lancet Neurol , vol.4 , pp. 476-486
    • Duffau, H.1
  • 11
    • 84862638474 scopus 로고    scopus 로고
    • The challenge to remove diffuse low-grade gliomas while preserving brain functions
    • Duffau H. The challenge to remove diffuse low-grade gliomas while preserving brain functions. Acta Neurochir (Wien). 2012;154:569–74.
    • (2012) Acta Neurochir (Wien) , vol.154 , pp. 569-574
    • Duffau, H.1
  • 12
    • 79961071375 scopus 로고    scopus 로고
    • Awake surgery for WHO Grade II gliomas within “noneloquent” areas in the left dominant hemisphere: toward a “supratotal” resection: clinical article
    • PID: 21548750
    • Yordanova YN, Moritz-Gasser S, Duffau H. Awake surgery for WHO Grade II gliomas within “noneloquent” areas in the left dominant hemisphere: toward a “supratotal” resection: clinical article. J Neurosurg. 2011;115:232–9.
    • (2011) J Neurosurg , vol.115 , pp. 232-239
    • Yordanova, Y.N.1    Moritz-Gasser, S.2    Duffau, H.3
  • 13
    • 84951905728 scopus 로고    scopus 로고
    • Long-term outcomes after supratotal resection of diffuse low-grade gliomas: a consecutive series with 11-year follow-up
    • Duffau H. Long-term outcomes after supratotal resection of diffuse low-grade gliomas: a consecutive series with 11-year follow-up. Acta Neurochir (Wien). 2016;158:51–8.
    • (2016) Acta Neurochir (Wien) , vol.158 , pp. 51-58
    • Duffau, H.1
  • 14
    • 77956227086 scopus 로고    scopus 로고
    • Interobserver variation of the histopathological diagnosis in clinical trials on glioma: a clinician’s perspective
    • PID: 20644945
    • van den Bent MJ. Interobserver variation of the histopathological diagnosis in clinical trials on glioma: a clinician’s perspective. Acta Neuropathol. 2010;120:297–304.
    • (2010) Acta Neuropathol , vol.120 , pp. 297-304
    • van den Bent, M.J.1
  • 15
    • 84932628860 scopus 로고    scopus 로고
    • Comprehensive, integrative genomic analysis of diffuse lower-grade gliomas
    • Cancer Genome Atlas Research Network, Brat DJ, Verhaak RG, Aldape KD, Yung WK, Salama SR, Cooper LA, et al. Comprehensive, integrative genomic analysis of diffuse lower-grade gliomas. N Engl J Med. 2015;372:2481–98.
    • (2015) N Engl J Med , vol.372 , pp. 2481-2498
    • Brat, D.J.1    Verhaak, R.G.2    Aldape, K.D.3    Yung, W.K.4    Salama, S.R.5    Cooper, L.A.6
  • 16
  • 17
    • 84939979467 scopus 로고    scopus 로고
    • IDH mutation status and role of WHO grade and mitotic index in overall survival in grade II–III diffuse gliomas
    • COI: 1:CAS:528:DC%2BC2MXjs1Glu7k%3D, PID: 25701198
    • Olar A, Wani KM, Alfaro-Munoz KD, Heathcock LE, van Thuijl HF, Gilbert MR, et al. IDH mutation status and role of WHO grade and mitotic index in overall survival in grade II–III diffuse gliomas. Acta Neuropathol. 2015;129:585–96.
    • (2015) Acta Neuropathol , vol.129 , pp. 585-596
    • Olar, A.1    Wani, K.M.2    Alfaro-Munoz, K.D.3    Heathcock, L.E.4    van Thuijl, H.F.5    Gilbert, M.R.6
  • 18
    • 84929709037 scopus 로고    scopus 로고
    • IDH mutant diffuse and anaplastic astrocytomas have similar age at presentation and little difference in survival: a grading problem for WHO
    • COI: 1:CAS:528:DC%2BC2MXos1Oisbk%3D, PID: 25962792
    • Reuss DE, Mamatjan Y, Schrimpf D, Capper D, Hovestadt V, Kratz A, et al. IDH mutant diffuse and anaplastic astrocytomas have similar age at presentation and little difference in survival: a grading problem for WHO. Acta Neuropathol. 2015;129:867–73.
    • (2015) Acta Neuropathol , vol.129 , pp. 867-873
    • Reuss, D.E.1    Mamatjan, Y.2    Schrimpf, D.3    Capper, D.4    Hovestadt, V.5    Kratz, A.6
  • 19
    • 84919921568 scopus 로고    scopus 로고
    • Farewell to oligoastrocytoma: in situ molecular genetics favor classification as either oligodendroglioma or astrocytoma
    • COI: 1:CAS:528:DC%2BC2cXhsVeqt73N, PID: 25143301
    • Sahm F, Reuss D, Koelsche C, Capper D, Schittenhelm J, Heim S, et al. Farewell to oligoastrocytoma: in situ molecular genetics favor classification as either oligodendroglioma or astrocytoma. Acta Neuropathol. 2014;128:551–9.
    • (2014) Acta Neuropathol , vol.128 , pp. 551-559
    • Sahm, F.1    Reuss, D.2    Koelsche, C.3    Capper, D.4    Schittenhelm, J.5    Heim, S.6
  • 21
    • 38949200071 scopus 로고    scopus 로고
    • Seizure characteristics and control following resection in 332 patients with low-grade gliomas
    • PID: 18240916
    • Chang EF, Potts MB, Keles GE, Lamborn KR, Chang SM, Barbaro NM, et al. Seizure characteristics and control following resection in 332 patients with low-grade gliomas. J Neurosurg. 2008;108:227–35.
    • (2008) J Neurosurg , vol.108 , pp. 227-235
    • Chang, E.F.1    Potts, M.B.2    Keles, G.E.3    Lamborn, K.R.4    Chang, S.M.5    Barbaro, N.M.6
  • 22
    • 1242293801 scopus 로고    scopus 로고
    • Cognitive deficits in adult patients with brain tumours
    • PID: 14980531
    • Taphoorn MJ, Klein M. Cognitive deficits in adult patients with brain tumours. Lancet Neurol. 2004;3:159–68.
    • (2004) Lancet Neurol , vol.3 , pp. 159-168
    • Taphoorn, M.J.1    Klein, M.2
  • 24
    • 1042278084 scopus 로고    scopus 로고
    • Neurocognitive sequelae in the treatment of low-grade gliomas
    • PID: 14765385
    • Taphoorn MJ. Neurocognitive sequelae in the treatment of low-grade gliomas. Semin Oncol. 2003;30(6 Suppl 19):45–8.
    • (2003) Semin Oncol , vol.30 , pp. 45-48
    • Taphoorn, M.J.1
  • 25
    • 0028200573 scopus 로고
    • Cognitive functions and quality of life in patients with low-grade gliomas: the impact of radiotherapy
    • COI: 1:STN:280:DyaK2c3ps1SltQ%3D%3D, PID: 8024261
    • Taphoorn MJ, Schiphorst AK, Snoek FJ, Lindeboom J, Wolbers JG, Karim AB, et al. Cognitive functions and quality of life in patients with low-grade gliomas: the impact of radiotherapy. Ann Neurol. 1994;36:48–54.
    • (1994) Ann Neurol. , vol.36 , pp. 48-54
    • Taphoorn, M.J.1    Schiphorst, A.K.2    Snoek, F.J.3    Lindeboom, J.4    Wolbers, J.G.5    Karim, A.B.6
  • 26
    • 77955817286 scopus 로고    scopus 로고
    • Guidelines on management of low-grade gliomas: report of an EFNS-EANO Task Force
    • COI: 1:STN:280:DC%2BC3cjlvVCqtg%3D%3D, PID: 20718851
    • Soffietti R, Baumert BG, Bello L, von Deimling A, Duffau H, Frénay M, et al. Guidelines on management of low-grade gliomas: report of an EFNS-EANO Task Force. Eur J Neurol. 2010;17:1124–33.
    • (2010) Eur J Neurol , vol.17 , pp. 1124-1133
    • Soffietti, R.1    Baumert, B.G.2    Bello, L.3    von Deimling, A.4    Duffau, H.5    Frénay, M.6
  • 27
    • 84877145540 scopus 로고    scopus 로고
    • Velocity of tumor spontaneous expansion predicts long-term outcomes for diffuse low-grade gliomas
    • PID: 23393207
    • Pallud J, Blonski M, Mandonnet E, Audureau E, Fontaine D, et al. Velocity of tumor spontaneous expansion predicts long-term outcomes for diffuse low-grade gliomas. Neuro Oncol. 2013;15:595–606.
    • (2013) Neuro Oncol. , vol.15 , pp. 595-606
    • Pallud, J.1    Blonski, M.2    Mandonnet, E.3    Audureau, E.4    Fontaine, D.5
  • 28
    • 33749476226 scopus 로고    scopus 로고
    • Prognostic value of initial magnetic resonance imaging growth rates for World Health Organization grade II gliomas
    • PID: 16983683
    • Pallud J, Mandonnet E, Duffau H, Kujas M, Guillevin R, Galanaud D, et al. Prognostic value of initial magnetic resonance imaging growth rates for World Health Organization grade II gliomas. Ann Neurol. 2006;60:380–3.
    • (2006) Ann Neurol. , vol.60 , pp. 380-383
    • Pallud, J.1    Mandonnet, E.2    Duffau, H.3    Kujas, M.4    Guillevin, R.5    Galanaud, D.6
  • 29
    • 20444401893 scopus 로고    scopus 로고
    • Medical Research Council MESS Study Group. Immediate versus deferred antiepileptic drug treatment for early epilepsy and single seizures: a randomised controlled trial
    • COI: 1:CAS:528:DC%2BD2MXltFSmu7c%3D, PID: 15950714
    • Marson A, Jacoby A, Johnson A, Kim L, Gamble C, Chadwick D. Medical Research Council MESS Study Group. Immediate versus deferred antiepileptic drug treatment for early epilepsy and single seizures: a randomised controlled trial. Lancet. 2005;365:2007–13.
    • (2005) Lancet , vol.365 , pp. 2007-2013
    • Marson, A.1    Jacoby, A.2    Johnson, A.3    Kim, L.4    Gamble, C.5    Chadwick, D.6
  • 30
    • 84965071538 scopus 로고    scopus 로고
    • Immediate antiepileptic drug treatment, versus placebo, deferred, or no treatment for first unprovoked seizure
    • Leone MA, Giussani G, Nolan SJ, Marson AG, Beghi E. Immediate antiepileptic drug treatment, versus placebo, deferred, or no treatment for first unprovoked seizure. Cochrane Database Syst Rev. 2016;5:CD007144.
    • (2016) Cochrane Database Syst Rev , vol.5 , pp. CD007144
    • Leone, M.A.1    Giussani, G.2    Nolan, S.J.3    Marson, A.G.4    Beghi, E.5
  • 31
    • 0036316649 scopus 로고    scopus 로고
    • Medically intractable epilepsy from insular low-grade gliomas: improvement after an extended lesionectomy
    • COI: 1:STN:280:DC%2BD38zmsFyntQ%3D%3D, (discussion 572-3
    • Duffau H, Capelle L, Lopes M, Bitar A, Sichez JP, van Effenterre R. Medically intractable epilepsy from insular low-grade gliomas: improvement after an extended lesionectomy. Acta Neurochir (Wien). 2002;144:563–72 (discussion 572–3).
    • (2002) Acta Neurochir (Wien) , vol.144 , pp. 563-572
    • Duffau, H.1    Capelle, L.2    Lopes, M.3    Bitar, A.4    Sichez, J.P.5    van Effenterre, R.6
  • 32
    • 84868016792 scopus 로고    scopus 로고
    • Seizures in low-grade gliomas: natural history, pathogenesis, and outcome after treatments
    • PID: 23095831
    • Rudà R, Bello L, Duffau H, Soffietti R. Seizures in low-grade gliomas: natural history, pathogenesis, and outcome after treatments. Neuro Oncol. 2012;14(Suppl 4):iv55–64.
    • (2012) Neuro Oncol. , vol.14 , pp. iv55-iv64
    • Rudà, R.1    Bello, L.2    Duffau, H.3    Soffietti, R.4
  • 33
    • 84943184665 scopus 로고    scopus 로고
    • Clinical management of seizures in patients with low-grade glioma
    • PID: 26050593
    • Piotrowski AF, Blakeley J. Clinical management of seizures in patients with low-grade glioma. Semin Radiat Oncol. 2015;25:219–24.
    • (2015) Semin Radiat Oncol. , vol.25 , pp. 219-224
    • Piotrowski, A.F.1    Blakeley, J.2
  • 34
    • 34047270232 scopus 로고    scopus 로고
    • Epilepsy in patients with brain tumours: epidemiology, mechanisms, and management
    • PID: 17434097
    • van Breemen MS, Wilms EB, Vecht CJ. Epilepsy in patients with brain tumours: epidemiology, mechanisms, and management. Lancet Neurol. 2007;6:421–30.
    • (2007) Lancet Neurol , vol.6 , pp. 421-430
    • van Breemen, M.S.1    Wilms, E.B.2    Vecht, C.J.3
  • 35
    • 0027203945 scopus 로고
    • Effect of cranial irradiation on seizure frequency in adults with low-grade astrocytoma and medically intractable epilepsy
    • COI: 1:STN:280:DyaK3szlsVGrsw%3D%3D, PID: 8351019
    • Rogers LR, Morris HH, Lupica K. Effect of cranial irradiation on seizure frequency in adults with low-grade astrocytoma and medically intractable epilepsy. Neurology. 1993;43:1599–601.
    • (1993) Neurology. , vol.43 , pp. 1599-1601
    • Rogers, L.R.1    Morris, H.H.2    Lupica, K.3
  • 36
    • 0037167568 scopus 로고    scopus 로고
    • How often are nonenhancing supratentorial gliomas malignant? A population study
    • COI: 1:STN:280:DC%2BD38vovVWlsQ%3D%3D, PID: 12297589
    • Scott JN, Brasher PM, Sevick RJ, Rewcastle NB, Forsyth PA. How often are nonenhancing supratentorial gliomas malignant? A population study. Neurology. 2002;59:947–9.
    • (2002) Neurology. , vol.59 , pp. 947-949
    • Scott, J.N.1    Brasher, P.M.2    Sevick, R.J.3    Rewcastle, N.B.4    Forsyth, P.A.5
  • 37
    • 0032054259 scopus 로고    scopus 로고
    • The significance of lack of MR contrast enhancement of supratentorial brain tumors in adults: histopathological evaluation of a series
    • COI: 1:STN:280:DyaK1c7pslSitg%3D%3D, PID: 9537664
    • Ginsberg LE, Fuller GN, Hashmi M, Leeds NE, Schomer DF. The significance of lack of MR contrast enhancement of supratentorial brain tumors in adults: histopathological evaluation of a series. Surg Neurol. 1998;49:436–40.
    • (1998) Surg Neurol , vol.49 , pp. 436-440
    • Ginsberg, L.E.1    Fuller, G.N.2    Hashmi, M.3    Leeds, N.E.4    Schomer, D.F.5
  • 39
    • 55549104415 scopus 로고    scopus 로고
    • Low-grade glioma on stereotactic biopsy: how often is the diagnosis accurate?
    • COI: 1:STN:280:DC%2BD1cnmtVehsw%3D%3D, PID: 18855292
    • Muragaki Y, Chernov M, Maruyama T, Ochiai T, Taira T, Kubo O, et al. Low-grade glioma on stereotactic biopsy: how often is the diagnosis accurate? Minim Invasive Neurosurg. 2008;51:275–9.
    • (2008) Minim Invasive Neurosurg , vol.51 , pp. 275-279
    • Muragaki, Y.1    Chernov, M.2    Maruyama, T.3    Ochiai, T.4    Taira, T.5    Kubo, O.6
  • 40
    • 41649090186 scopus 로고    scopus 로고
    • Role of extent of resection in the long-term outcome of low-grade hemispheric gliomas
    • PID: 18323558
    • Smith JS, Chang EF, Lamborn KR, Chang SM, Prados MD, Cha S, et al. Role of extent of resection in the long-term outcome of low-grade hemispheric gliomas. J Clin Oncol. 2008;26:1338–45.
    • (2008) J Clin Oncol , vol.26 , pp. 1338-1345
    • Smith, J.S.1    Chang, E.F.2    Lamborn, K.R.3    Chang, S.M.4    Prados, M.D.5    Cha, S.6
  • 41
    • 56749091346 scopus 로고    scopus 로고
    • Extent of surgical resection is independently associated with survival in patients with hemispheric infiltrating low-grade gliomas
    • PID: 18981880, (author reply 707-8
    • McGirt MJ, Chaichana KL, Attenello FJ, Weingart JD, Than K, Burger PC, et al. Extent of surgical resection is independently associated with survival in patients with hemispheric infiltrating low-grade gliomas. Neurosurgery. 2008;63:700–7 (author reply 707-8).
    • (2008) Neurosurgery. , vol.63 , pp. 700-707
    • McGirt, M.J.1    Chaichana, K.L.2    Attenello, F.J.3    Weingart, J.D.4    Than, K.5    Burger, P.C.6
  • 42
    • 14744272782 scopus 로고    scopus 로고
    • Survival rates in patients with low-grade glioma after intraoperative magnetic resonance image guidance
    • PID: 15690327
    • Claus EB, Horlacher A, Hsu L, Schwartz RB, Dello-Iacono D, Talos F, et al. Survival rates in patients with low-grade glioma after intraoperative magnetic resonance image guidance. Cancer. 2005;103:1227–33.
    • (2005) Cancer , vol.103 , pp. 1227-1233
    • Claus, E.B.1    Horlacher, A.2    Hsu, L.3    Schwartz, R.B.4    Dello-Iacono, D.5    Talos, F.6
  • 43
    • 84870946553 scopus 로고    scopus 로고
    • Low-grade glioma surgery in eloquent areas: volumetric analysis of extent of resection and its impact on overall survival. A single-institution experience in 190 patients: clinical article
    • PID: 23039150
    • Ius T, Isola M, Budai R, Pauletto G, Tomasino B, Fadiga L, Skrap M. Low-grade glioma surgery in eloquent areas: volumetric analysis of extent of resection and its impact on overall survival. A single-institution experience in 190 patients: clinical article. J Neurosurg. 2012;117:1039–52.
    • (2012) J Neurosurg , vol.117 , pp. 1039-1052
    • Ius, T.1    Isola, M.2    Budai, R.3    Pauletto, G.4    Tomasino, B.5    Fadiga, L.6    Skrap, M.7
  • 44
    • 84940417545 scopus 로고    scopus 로고
    • Proposed therapeutic strategy for adult low-grade glioma based on aggressive tumor resection
    • PID: 25599276
    • Nitta M, Muragaki Y, Maruyama T, Ikuta S, Komori T, Maebayashi K, et al. Proposed therapeutic strategy for adult low-grade glioma based on aggressive tumor resection. Neurosurg Focus. 2015;38(1):E7.
    • (2015) Neurosurg Focus , vol.38 , Issue.1 , pp. E7
    • Nitta, M.1    Muragaki, Y.2    Maruyama, T.3    Ikuta, S.4    Komori, T.5    Maebayashi, K.6
  • 45
    • 20444404289 scopus 로고    scopus 로고
    • Contribution of intraoperative electrical stimulations in surgery of low grade gliomas: a comparative study between two series without (1985–96) and with (1996–2003) functional mapping in the same institution
    • COI: 1:STN:280:DC%2BD2M3ps1yitA%3D%3D, PID: 15897509
    • Duffau H, Lopes M, Arthuis F, Bitar A, Sichez JP, Van Effenterre R, et al. Contribution of intraoperative electrical stimulations in surgery of low grade gliomas: a comparative study between two series without (1985–96) and with (1996–2003) functional mapping in the same institution. J Neurol Neurosurg Psychiatry. 2005;76:845–51.
    • (2005) J Neurol Neurosurg Psychiatry , vol.76 , pp. 845-851
    • Duffau, H.1    Lopes, M.2    Arthuis, F.3    Bitar, A.4    Sichez, J.P.5    Van Effenterre, R.6
  • 46
    • 0142182641 scopus 로고    scopus 로고
    • Progress in long-term survival in adult patients with supratentorial low-grade gliomas: a population-based study of 993 patients in whom tumors were diagnosed between 1970 and 1993
    • PID: 14609165
    • Johannesen TB, Langmark F, Lote K. Progress in long-term survival in adult patients with supratentorial low-grade gliomas: a population-based study of 993 patients in whom tumors were diagnosed between 1970 and 1993. J Neurosurg. 2003;99:854–62.
    • (2003) J Neurosurg , vol.99 , pp. 854-862
    • Johannesen, T.B.1    Langmark, F.2    Lote, K.3
  • 47
    • 16344372438 scopus 로고    scopus 로고
    • Treatment outcomes and prognostic factors in patients with supratentorial low-grade gliomas
    • PID: 15730987
    • Yeh SA, Ho JT, Lui CC, Huang YJ, Hsiung CY, Huang EY. Treatment outcomes and prognostic factors in patients with supratentorial low-grade gliomas. Br J Radiol. 2005;78:230–5.
    • (2005) Br J Radiol , vol.78 , pp. 230-235
    • Yeh, S.A.1    Ho, J.T.2    Lui, C.C.3    Huang, Y.J.4    Hsiung, C.Y.5    Huang, E.Y.6
  • 48
    • 70449520170 scopus 로고    scopus 로고
    • Long-term outcome and survival of surgically treated supratentorial low-grade glioma in adult patients
    • Ahmadi R, Dictus C, Hartmann C, Zürn O, Edler L, Hartmann M, et al. Long-term outcome and survival of surgically treated supratentorial low-grade glioma in adult patients. Acta Neurochir (Wien). 2009;151:1359–65.
    • (2009) Acta Neurochir (Wien) , vol.151 , pp. 1359-1365
    • Ahmadi, R.1    Dictus, C.2    Hartmann, C.3    Zürn, O.4    Edler, L.5    Hartmann, M.6
  • 49
    • 68949107664 scopus 로고    scopus 로고
    • Intracranial low-grade gliomas in adults: 30-year experience with long-term follow-up at Mayo Clinic
    • PID: 19018039
    • Schomas DA, Laack NN, Rao RD, Meyer FB, Shaw EG, O’Neill BP, et al. Intracranial low-grade gliomas in adults: 30-year experience with long-term follow-up at Mayo Clinic. Neuro Oncol. 2009;11:437–45.
    • (2009) Neuro Oncol. , vol.11 , pp. 437-445
    • Schomas, D.A.1    Laack, N.N.2    Rao, R.D.3    Meyer, F.B.4    Shaw, E.G.5    O’Neill, B.P.6
  • 51
    • 84878737424 scopus 로고    scopus 로고
    • Spontaneous and therapeutic prognostic factors in adult hemispheric World Health Organization Grade II gliomas: a series of 1097 cases: clinical article
    • PID: 23495881
    • Capelle L, Fontaine D, Mandonnet E, Taillandier L, Golmard JL, Bauchet L, et al. Spontaneous and therapeutic prognostic factors in adult hemispheric World Health Organization Grade II gliomas: a series of 1097 cases: clinical article. J Neurosurg. 2013;118:1157–68.
    • (2013) J Neurosurg , vol.118 , pp. 1157-1168
    • Capelle, L.1    Fontaine, D.2    Mandonnet, E.3    Taillandier, L.4    Golmard, J.L.5    Bauchet, L.6
  • 52
    • 48949107730 scopus 로고    scopus 로고
    • Glioma extent of resection and its impact on patient outcome
    • PID: 18496181, (discussion 264-6
    • Sanai N, Berger MS. Glioma extent of resection and its impact on patient outcome. Neurosurgery. 2008;62:753–64 (discussion 264–6).
    • (2008) Neurosurgery. , vol.62 , pp. 753-764
    • Sanai, N.1    Berger, M.S.2
  • 53
    • 53449098450 scopus 로고    scopus 로고
    • Intraoperative subcortical stimulation mapping of language pathways in a consecutive series of 115 patients with Grade II glioma in the left dominant hemisphere
    • PID: 18759577
    • Duffau H, Peggy Gatignol ST, Mandonnet E, Capelle L, Taillandier L. Intraoperative subcortical stimulation mapping of language pathways in a consecutive series of 115 patients with Grade II glioma in the left dominant hemisphere. J Neurosurg. 2008;109:461–71.
    • (2008) J Neurosurg , vol.109 , pp. 461-471
    • Duffau, H.1    Peggy Gatignol, S.T.2    Mandonnet, E.3    Capelle, L.4    Taillandier, L.5
  • 54
    • 84874531290 scopus 로고    scopus 로고
    • Fiber dissection and diffusion tensor imaging tractography study of the temporoparietal fiber intersection area
    • PID: 23417154, (discussion 97–8
    • Martino J, Silva-Freitas R, Caballero H, Marco de Lucas E, García-Porrero JA, Vázquez-Barquero A. Fiber dissection and diffusion tensor imaging tractography study of the temporoparietal fiber intersection area. Neurosurgery. 2013;72(1 suppl operative):87–97 (discussion 97–8).
    • (2013) Neurosurgery. , vol.72 , pp. 87-97
    • Martino, J.1    Silva-Freitas, R.2    Caballero, H.3    Marco de Lucas, E.4    García-Porrero, J.A.5    Vázquez-Barquero, A.6
  • 55
    • 84872298214 scopus 로고    scopus 로고
    • Analysis of the subcomponents and cortical terminations of the perisylvian superior longitudinal fasciculus: a fiber dissection and DTI tractography study
    • PID: 22422148
    • Martino J, De Witt Hamer PC, Berger MS, Lawton MT, Arnold CM, de Lucas EM, et al. Analysis of the subcomponents and cortical terminations of the perisylvian superior longitudinal fasciculus: a fiber dissection and DTI tractography study. Brain Struct Funct. 2013;218:105–21.
    • (2013) Brain Struct Funct. , vol.218 , pp. 105-121
    • Martino, J.1    De Witt Hamer, P.C.2    Berger, M.S.3    Lawton, M.T.4    Arnold, C.M.5    de Lucas, E.M.6
  • 56
    • 84974593649 scopus 로고    scopus 로고
    • Application of awake craniotomy and intraoperative brain mapping for surgical resection of insular gliomas of the dominant hemisphere
    • PID: 27150651
    • Alimohamadi M, Shirani M, Shariat Moharari R, Pour-Rashidi A, Ketabchi M, Khajavi M, et al. Application of awake craniotomy and intraoperative brain mapping for surgical resection of insular gliomas of the dominant hemisphere. World Neurosurg. 2016;92:151–8.
    • (2016) World Neurosurg. , vol.92 , pp. 151-158
    • Alimohamadi, M.1    Shirani, M.2    Shariat Moharari, R.3    Pour-Rashidi, A.4    Ketabchi, M.5    Khajavi, M.6
  • 57
    • 84864056416 scopus 로고    scopus 로고
    • Impact of intraoperative stimulation brain mapping on glioma surgery outcome: a meta-analysis
    • PID: 22529254
    • De Witt Hamer PC, Robles SG, Zwinderman AH, Duffau H, Berger MS. Impact of intraoperative stimulation brain mapping on glioma surgery outcome: a meta-analysis. J Clin Oncol. 2012;30:2559–65.
    • (2012) J Clin Oncol , vol.30 , pp. 2559-2565
    • De Witt Hamer, P.C.1    Robles, S.G.2    Zwinderman, A.H.3    Duffau, H.4    Berger, M.S.5
  • 58
    • 84862679941 scopus 로고    scopus 로고
    • Awake surgery for incidental WHO grade II gliomas involving eloquent areas
    • discussion 584
    • Duffau H. Awake surgery for incidental WHO grade II gliomas involving eloquent areas. Acta Neurochir (Wien). 2012;154:575–84 (discussion 584).
    • (2012) Acta Neurochir (Wien) , vol.154 , pp. 575-584
    • Duffau, H.1
  • 59
    • 84938504590 scopus 로고    scopus 로고
    • Is there a risk of seizures in “preventive” awake surgery for incidental diffuse low-grade gliomas?
    • PID: 25723301
    • Lima GL, Duffau H. Is there a risk of seizures in “preventive” awake surgery for incidental diffuse low-grade gliomas? J Neurosurg. 2015;122:1397–405.
    • (2015) J Neurosurg , vol.122 , pp. 1397-1405
    • Lima, G.L.1    Duffau, H.2
  • 60
    • 84922983041 scopus 로고    scopus 로고
    • Diffuse low-grade gliomas and neuroplasticity
    • COI: 1:STN:280:DC%2BC2M7htVGntw%3D%3D, PID: 25218490
    • Duffau H. Diffuse low-grade gliomas and neuroplasticity. Diagn Interv Imaging. 2014;95:945–55.
    • (2014) Diagn Interv Imaging. , vol.95 , pp. 945-955
    • Duffau, H.1
  • 61
    • 33745966235 scopus 로고    scopus 로고
    • New concepts in surgery of WHO grade II gliomas: functional brain mapping, connectionism and plasticity–a review
    • PID: 16607477
    • Duffau H. New concepts in surgery of WHO grade II gliomas: functional brain mapping, connectionism and plasticity–a review. J Neurooncol. 2006;79:77–115.
    • (2006) J Neurooncol , vol.79 , pp. 77-115
    • Duffau, H.1
  • 62
    • 68249131500 scopus 로고    scopus 로고
    • Cognitive and radiological effects of radiotherapy in patients with low-grade glioma: long-term follow-up
    • PID: 19665931
    • Douw L, Klein M, Fagel SS, van den Heuvel J, Taphoorn MJ, Aaronson NK, et al. Cognitive and radiological effects of radiotherapy in patients with low-grade glioma: long-term follow-up. Lancet Neurol. 2009;8:810–8.
    • (2009) Lancet Neurol , vol.8 , pp. 810-818
    • Douw, L.1    Klein, M.2    Fagel, S.S.3    van den Heuvel, J.4    Taphoorn, M.J.5    Aaronson, N.K.6
  • 63
    • 85016649780 scopus 로고    scopus 로고
    • Early versus delayed postoperative radiotherapy for treatment of low-grade gliomas
    • Sarmiento JM, Venteicher AS, Patil CG. Early versus delayed postoperative radiotherapy for treatment of low-grade gliomas. Cochrane Database Syst Rev. 2015;6:CD009229.
    • (2015) Cochrane Database Syst Rev , vol.6 , pp. CD009229
    • Sarmiento, J.M.1    Venteicher, A.S.2    Patil, C.G.3
  • 64
    • 10544231454 scopus 로고    scopus 로고
    • A randomized trial on dose-response in radiation therapy of low-grade cerebral glioma: European Organization for Research and Treatment of Cancer (EORTC) Study 22844
    • COI: 1:STN:280:DyaK2s7gsVWrsg%3D%3D, PID: 8948338
    • Karim AB, Maat B, Hatlevoll R, Menten J, Rutten EH, Thomas DG, et al. A randomized trial on dose-response in radiation therapy of low-grade cerebral glioma: European Organization for Research and Treatment of Cancer (EORTC) Study 22844. Int J Radiat Oncol Biol Phys. 1996;36:549–56.
    • (1996) Int J Radiat Oncol Biol Phys , vol.36 , pp. 549-556
    • Karim, A.B.1    Maat, B.2    Hatlevoll, R.3    Menten, J.4    Rutten, E.H.5    Thomas, D.G.6
  • 65
    • 0036569467 scopus 로고    scopus 로고
    • Prospective randomized trial of low- versus high-dose radiation therapy in adults with supratentorial low-grade glioma: initial report of a North Central Cancer Treatment Group/Radiation Therapy Oncology Group/Eastern Cooperative Oncology Group study
    • COI: 1:STN:280:DC%2BD383ktlektg%3D%3D, PID: 11980997
    • Shaw E, Arusell R, Scheithauer B, O’Fallon J, O’Neill B, Dinapoli R, et al. Prospective randomized trial of low- versus high-dose radiation therapy in adults with supratentorial low-grade glioma: initial report of a North Central Cancer Treatment Group/Radiation Therapy Oncology Group/Eastern Cooperative Oncology Group study. J Clin Oncol. 2002;20:2267–76.
    • (2002) J Clin Oncol , vol.20 , pp. 2267-2276
    • Shaw, E.1    Arusell, R.2    Scheithauer, B.3    O’Fallon, J.4    O’Neill, B.5    Dinapoli, R.6
  • 66
    • 24944439786 scopus 로고    scopus 로고
    • Long-term efficacy of early versus delayed radiotherapy for low-grade astrocytoma and oligodendroglioma in adults: the EORTC 22845 randomised trial
    • PID: 16168780
    • van den Bent MJ, Afra D, de Witte O, Ben Hassel M, Schraub S, Hoang-Xuan K, et al. Long-term efficacy of early versus delayed radiotherapy for low-grade astrocytoma and oligodendroglioma in adults: the EORTC 22845 randomised trial. Lancet. 2005;366(9490):985–90.
    • (2005) Lancet , vol.366 , Issue.9490 , pp. 985-990
    • van den Bent, M.J.1    Afra, D.2    de Witte, O.3    Ben Hassel, M.4    Schraub, S.5    Hoang-Xuan, K.6
  • 67
    • 84963804957 scopus 로고    scopus 로고
    • Radiation plus procarbazine, CCNU, and vincristine in low-grade glioma
    • COI: 1:CAS:528:DC%2BC28XhtFGqsbfM, PID: 27050206
    • Buckner JC, Shaw EG, Pugh SL, Chakravarti A, Gilbert MR, Barger GR, et al. Radiation plus procarbazine, CCNU, and vincristine in low-grade glioma. N Engl J Med. 2016;374:1344–55.
    • (2016) N Engl J Med , vol.374 , pp. 1344-1355
    • Buckner, J.C.1    Shaw, E.G.2    Pugh, S.L.3    Chakravarti, A.4    Gilbert, M.R.5    Barger, G.R.6
  • 68
    • 0035933187 scopus 로고    scopus 로고
    • Adverse long-term effects of brain radiotherapy in adult low-grade glioma patients
    • COI: 1:STN:280:DC%2BD3M3ps1SrtA%3D%3D, PID: 11376174
    • Surma-aho O, Niemelä M, Vilkki J, Kouri M, Brander A, Salonen O, et al. Adverse long-term effects of brain radiotherapy in adult low-grade glioma patients. Neurology. 2001;56:1285–90.
    • (2001) Neurology. , vol.56 , pp. 1285-1290
    • Surma-aho, O.1    Niemelä, M.2    Vilkki, J.3    Kouri, M.4    Brander, A.5    Salonen, O.6
  • 69
    • 84891870744 scopus 로고    scopus 로고
    • New validated prognostic models and prognostic calculators in patients with low-grade gliomas diagnosed by central pathology review: a pooled analysis of EORTC/RTOG/NCCTG phase III clinical trials
    • PID: 24049111
    • Gorlia T, Wu W, Wang M, Baumert BG, Mehta M, Buckner JC, et al. New validated prognostic models and prognostic calculators in patients with low-grade gliomas diagnosed by central pathology review: a pooled analysis of EORTC/RTOG/NCCTG phase III clinical trials. Neuro Oncol. 2013;15:1568–79.
    • (2013) Neuro Oncol. , vol.15 , pp. 1568-1579
    • Gorlia, T.1    Wu, W.2    Wang, M.3    Baumert, B.G.4    Mehta, M.5    Buckner, J.C.6
  • 70
    • 84995596353 scopus 로고    scopus 로고
    • Temozolomide chemotherapy versus radiotherapy in high-risk low-grade glioma (EORTC 22033–26033): a randomised, open-label, phase 3 intergroup study
    • COI: 1:CAS:528:DC%2BC28Xhs1Wns77K, PID: 27686946
    • Baumert BG, Hegi ME, van den Bent MJ, von Deimling A, Gorlia T, Hoang-Xuan K, et al. Temozolomide chemotherapy versus radiotherapy in high-risk low-grade glioma (EORTC 22033–26033): a randomised, open-label, phase 3 intergroup study. Lancet Oncol. 2016;17:1521–32.
    • (2016) Lancet Oncol. , vol.17 , pp. 1521-1532
    • Baumert, B.G.1    Hegi, M.E.2    van den Bent, M.J.3    von Deimling, A.4    Gorlia, T.5    Hoang-Xuan, K.6
  • 71
    • 84995543012 scopus 로고    scopus 로고
    • Health-related quality of life in patients with high-risk low-grade glioma (EORTC 22033–26033): a randomised, open-label, phase 3 intergroup study
    • PID: 27686943
    • Reijneveld JC, Taphoorn MJ, Coens C, Bromberg JE, Mason WP, Hoang-Xuan K, et al. Health-related quality of life in patients with high-risk low-grade glioma (EORTC 22033–26033): a randomised, open-label, phase 3 intergroup study. Lancet Oncol. 2016;17:1533–42.
    • (2016) Lancet Oncol. , vol.17 , pp. 1533-1542
    • Reijneveld, J.C.1    Taphoorn, M.J.2    Coens, C.3    Bromberg, J.E.4    Mason, W.P.5    Hoang-Xuan, K.6
  • 72
    • 84954240770 scopus 로고    scopus 로고
    • Current management of adult diffuse infiltrative low grade gliomas
    • PID: 26750130
    • Le Rhun E, Taillibert S, Chamberlain MC. Current management of adult diffuse infiltrative low grade gliomas. Curr Neurol Neurosci Rep. 2016;16:15.
    • (2016) Curr Neurol Neurosci Rep , vol.16 , pp. 15
    • Le Rhun, E.1    Taillibert, S.2    Chamberlain, M.C.3
  • 73
    • 85050579144 scopus 로고    scopus 로고
    • Procarbazine, lomustine and vincristine or temozolomide: which is the better regimen CNS
    • COI: 1:CAS:528:DC%2BC2MXhvVCru77J
    • Lassman AB. Procarbazine, lomustine and vincristine or temozolomide: which is the better regimen CNS. Oncology. 2015;4:341–6.
    • (2015) Oncology , vol.4 , pp. 341-346
    • Lassman, A.B.1
  • 74
    • 4143143288 scopus 로고    scopus 로고
    • Temozolomide as initial treatment for adults with low-grade oligodendrogliomas or oligoastrocytomas and correlation with chromosome 1p deletions
    • COI: 1:CAS:528:DC%2BD2cXpsVGrs7o%3D, PID: 15284265
    • Hoang-Xuan K, Capelle L, Kujas M, Taillibert S, Duffau H, Lejeune J, et al. Temozolomide as initial treatment for adults with low-grade oligodendrogliomas or oligoastrocytomas and correlation with chromosome 1p deletions. J Clin Oncol. 2004;22:3133–8.
    • (2004) J Clin Oncol , vol.22 , pp. 3133-3138
    • Hoang-Xuan, K.1    Capelle, L.2    Kujas, M.3    Taillibert, S.4    Duffau, H.5    Lejeune, J.6
  • 75
    • 73349134695 scopus 로고    scopus 로고
    • NOA-04 randomized phase III trial of sequential radiochemotherapy of anaplastic glioma with procarbazine, lomustine, and vincristine or temozolomide
    • COI: 1:CAS:528:DC%2BC3cXhtVWis7g%3D, PID: 19901110
    • Wick W, Hartmann C, Engel C, Stoffels M, Felsberg J, Stockhammer F, et al. NOA-04 randomized phase III trial of sequential radiochemotherapy of anaplastic glioma with procarbazine, lomustine, and vincristine or temozolomide. J Clin Oncol. 2009;27:5874–80.
    • (2009) J Clin Oncol , vol.27 , pp. 5874-5880
    • Wick, W.1    Hartmann, C.2    Engel, C.3    Stoffels, M.4    Felsberg, J.5    Stockhammer, F.6
  • 76
    • 84873338121 scopus 로고    scopus 로고
    • Phase III trial of chemoradiotherapy for anaplastic oligodendroglioma: long-term results of RTOG 9402
    • COI: 1:CAS:528:DC%2BC3sXis1Cgtbk%3D, PID: 23071247
    • Cairncross G, Wang M, Shaw E, Jenkins R, Brachman D, Buckner J, et al. Phase III trial of chemoradiotherapy for anaplastic oligodendroglioma: long-term results of RTOG 9402. J Clin Oncol. 2013;31:337–43.
    • (2013) J Clin Oncol , vol.31 , pp. 337-343
    • Cairncross, G.1    Wang, M.2    Shaw, E.3    Jenkins, R.4    Brachman, D.5    Buckner, J.6
  • 77
    • 84873345824 scopus 로고    scopus 로고
    • Adjuvant procarbazine, lomustine, and vincristine chemotherapy in newly diagnosed anaplastic oligodendroglioma: long-term follow-up of EORTC brain tumor group study 26951
    • PID: 23071237
    • van den Bent MJ, Brandes AA, Taphoorn MJ, Kros JM, Kouwenhoven MC, Delattre JY, et al. Adjuvant procarbazine, lomustine, and vincristine chemotherapy in newly diagnosed anaplastic oligodendroglioma: long-term follow-up of EORTC brain tumor group study 26951. J Clin Oncol. 2013;31:344–50.
    • (2013) J Clin Oncol , vol.31 , pp. 344-350
    • van den Bent, M.J.1    Brandes, A.A.2    Taphoorn, M.J.3    Kros, J.M.4    Kouwenhoven, M.C.5    Delattre, J.Y.6
  • 79
    • 85050579407 scopus 로고    scopus 로고
    • Anaplastic astrocytoma
    • COI: 1:CAS:528:DC%2BC28XhtVWlsLrJ, PID: 27230974
    • Grimm SA, Chamberlain MC. Anaplastic astrocytoma. CNS Oncol. 2016;5:145–57.
    • (2016) CNS Oncol. , vol.5 , pp. 145-157
    • Grimm, S.A.1    Chamberlain, M.C.2
  • 80
    • 84923247998 scopus 로고    scopus 로고
    • Phase 2 study of temozolomide-based chemoradiation therapy for high-risk low-grade gliomas: preliminary results of Radiation Therapy Oncology Group 0424
    • COI: 1:CAS:528:DC%2BC2MXitFOqs7w%3D, PID: 25680596
    • Fisher BJ, Hu C, Macdonald DR, Lesser GJ, Coons SW, Brachman DG, et al. Phase 2 study of temozolomide-based chemoradiation therapy for high-risk low-grade gliomas: preliminary results of Radiation Therapy Oncology Group 0424. Int J Radiat Oncol Biol Phys. 2015;91:497–504.
    • (2015) Int J Radiat Oncol Biol Phys , vol.91 , pp. 497-504
    • Fisher, B.J.1    Hu, C.2    Macdonald, D.R.3    Lesser, G.J.4    Coons, S.W.5    Brachman, D.G.6
  • 81
    • 84947491421 scopus 로고    scopus 로고
    • Chemotherapy for low-grade glioma: when, for whom, which regimen?
    • PID: 26397230
    • van den Bent MJ. Chemotherapy for low-grade glioma: when, for whom, which regimen? Curr Opin Neurol. 2015;28:633–938.
    • (2015) Curr Opin Neurol , vol.28 , pp. 633-938
    • van den Bent, M.J.1
  • 82
    • 84947492049 scopus 로고    scopus 로고
    • The role of emerging therapy in the management of patients with diffuse low grade glioma
    • COI: 1:CAS:528:DC%2BC2MXhvVegt7fN, PID: 26530260
    • Sloan AE, Okada H, Ryken TC, Kalkanis SN, Olson JJ. The role of emerging therapy in the management of patients with diffuse low grade glioma. J Neurooncol. 2015;125(3):631–5. doi:10.1007/s11060-015-1865-3.
    • (2015) J Neurooncol , vol.125 , Issue.3 , pp. 631-635
    • Sloan, A.E.1    Okada, H.2    Ryken, T.C.3    Kalkanis, S.N.4    Olson, J.J.5
  • 83
    • 84920969943 scopus 로고    scopus 로고
    • Induction of robust type-I CD8 + T-cell responses in WHO grade 2 low-grade glioma patients receiving peptide-based vaccines in combination with poly-ICLC
    • COI: 1:CAS:528:DC%2BC2MXhtlGrs78%3D, PID: 25424847
    • Okada H, Butterfield LH, Hamilton RL, Hoji A, Sakaki M, Ahn BJ, et al. Induction of robust type-I CD8 + T-cell responses in WHO grade 2 low-grade glioma patients receiving peptide-based vaccines in combination with poly-ICLC. Clin Cancer Res. 2015;21(2):286–94. doi:10.1158/1078-0432.CCR-14-1790.
    • (2015) Clin Cancer Res , vol.21 , Issue.2 , pp. 286-294
    • Okada, H.1    Butterfield, L.H.2    Hamilton, R.L.3    Hoji, A.4    Sakaki, M.5    Ahn, B.J.6
  • 84
    • 77952293847 scopus 로고    scopus 로고
    • Daily intake of antioxidants in relation to survival among adult patients diagnosed with malignant glioma
    • DeLorenze GN, McCoy L, Tsai AL, Quesenberry CP Jr, Rice T, Il’yasova D, et al. Daily intake of antioxidants in relation to survival among adult patients diagnosed with malignant glioma. BMC Cancer. 2010;19(10):215. doi:10.1186/1471-2407-10-215.
    • (2010) BMC Cancer , vol.19 , Issue.10 , pp. 215
    • DeLorenze, G.N.1    McCoy, L.2    Tsai, A.L.3    Quesenberry, C.P.4    Rice, T.5    Il’yasova, D.6
  • 85
    • 77952170131 scopus 로고    scopus 로고
    • Persistent outpatient hyperglycemia is independently associated with survival, recurrence and malignant degeneration following surgery for hemispheric low grade gliomas
    • PID: 19589201
    • Chaichana KL, McGirt MJ, Woodworth GF, Datoo G, Tamargo RJ, Weingart J, et al. Persistent outpatient hyperglycemia is independently associated with survival, recurrence and malignant degeneration following surgery for hemispheric low grade gliomas. Neurol Res. 2010;32(4):442–8.
    • (2010) Neurol Res , vol.32 , Issue.4 , pp. 442-448
    • Chaichana, K.L.1    McGirt, M.J.2    Woodworth, G.F.3    Datoo, G.4    Tamargo, R.J.5    Weingart, J.6
  • 86
    • 78650829482 scopus 로고    scopus 로고
    • Complementary therapy use in patients with glioma: an observational study
    • COI: 1:STN:280:DC%2BC3M%2FptFyntA%3D%3D, PID: 21172846
    • Heese O, Schmidt M, Nickel S, Berger H, Goldbrunner R, Tonn JC, et al. Complementary therapy use in patients with glioma: an observational study. Neurology. 2010;75(24):2229–35. doi:10.1212/WNL.0b013e31820202c6.
    • (2010) Neurology. , vol.75 , Issue.24 , pp. 2229-2235
    • Heese, O.1    Schmidt, M.2    Nickel, S.3    Berger, H.4    Goldbrunner, R.5    Tonn, J.C.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.