Application of single-cell RNA sequencing in optimizing a combinatorial therapeutic strategy in metastatic renal cell carcinoma

Genome biology

Volumn 17, Issue , 2016, Pages 80-

  Kim, Kyu Tae ^a   Lee, Hye Won ^b   Lee, Hae Ock ^a,b   Song, Hye Jin ^b   Jeong, Da Eun ^a   Shin, Sang ^b   Kim, Hyunho ^b   Shin, Yoojin ^a   Nam, Do Hyun ^a,b   Jeong, Byong Chang ^b   Kirsch, David G ^b   Joo, Kyeung Min ^b   Park, Woong Yang ^b  

^a Samsung Medical Center   (South Korea)

^b Sungkyunkwan University   (South Korea)

Author keywords

Drug response; Patient derived xenograft; Renal cell carcinoma; Single cell analysis; Tumor heterogeneity

Indexed keywords

ADULT; ANIMAL; CARCINOMA, RENAL CELL; CELL CULTURE; GENE EXPRESSION PROFILING; GENETICS; HUMAN; KIDNEY NEOPLASMS; LUNG NEOPLASMS; MALE; MOLECULARLY TARGETED THERAPY; MOUSE; PATHOLOGY; PROCEDURES; SECONDARY; SEQUENCE ANALYSIS; SINGLE CELL ANALYSIS;

ADULT; ANIMALS; CARCINOMA, RENAL CELL; CELLS, CULTURED; GENE EXPRESSION PROFILING; HUMANS; KIDNEY NEOPLASMS; LUNG NEOPLASMS; MALE; MICE; MOLECULAR TARGETED THERAPY; SEQUENCE ANALYSIS, RNA; SINGLE-CELL ANALYSIS;

EID: 85014067631     PISSN: None     EISSN: 1474760X     Source Type: Journal    
DOI: 10.1186/s13059-016-0945-9     Document Type: Article

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