RSV associated hospitalizations in children in Karachi, Pakistan: Implications for vaccine prevention strategies

Journal of Medical Virology

Volumn 89, Issue 7, 2017, Pages 1151-1157

  Ali, Asad ^a   Yousafzai, Mohammad Tahir ^a   Waris, Rabbia ^a   Jafri, Fatima ^a   Aziz, Fatima ^a   Abbasi, Imran Naeem ^a   Zaidi, Anita ^a  

^a AGA KHAN UNIVERSITY   (Pakistan)

Author keywords

ARI; asthma; bronchiolitis; Karachi; log binomial regression; Pakistan; pneumonia; respiratory syncytial virus; RSV

Indexed keywords

RESPIRATORY SYNCYTIAL VIRUS VACCINE;

AGE DISTRIBUTION; ARTICLE; ASTHMA; BRONCHIOLITIS; CHILD; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; COUGHING; DISEASE ASSOCIATION; DISEASE SEVERITY; FEMALE; HOSPITALIZATION; HUMAN; INFECTION RATE; MAJOR CLINICAL STUDY; MALE; NOSE OBSTRUCTION; PAKISTAN; PNEUMONIA; PREVALENCE; PROSPECTIVE STUDY; REAL TIME POLYMERASE CHAIN REACTION; RESPIRATORY SYNCYTIAL VIRUS INFECTION; RISK FACTOR; SEASONAL VARIATION; THROAT CULTURE; UPPER RESPIRATORY TRACT INFECTION; ACUTE DISEASE; GENETICS; HUMAN RESPIRATORY SYNCYTIAL VIRUS; INFANT; ISOLATION AND PURIFICATION; PHARYNX; PRESCHOOL CHILD; REGRESSION ANALYSIS; RESPIRATORY TRACT INFECTION; STATISTICS AND NUMERICAL DATA; VIROLOGY; VIRUS PNEUMONIA;

ACUTE DISEASE; ASTHMA; BRONCHIOLITIS; CHILD, PRESCHOOL; FEMALE; HOSPITALIZATION; HUMANS; INFANT; MALE; PAKISTAN; PHARYNX; PNEUMONIA, VIRAL; PROSPECTIVE STUDIES; REAL-TIME POLYMERASE CHAIN REACTION; REGRESSION ANALYSIS; RESPIRATORY SYNCYTIAL VIRUS INFECTIONS; RESPIRATORY SYNCYTIAL VIRUS VACCINES; RESPIRATORY SYNCYTIAL VIRUS, HUMAN; RESPIRATORY TRACT INFECTIONS;

EID: 85013774890     PISSN: 01466615     EISSN: 10969071     Source Type: Journal    
DOI: 10.1002/jmv.24768     Document Type: Article

References (16)

1. Nair H, Nokes DJ, Gessner BD, et al. Global burden of acute lower respiratory infections due to respiratory syncytial virus in young children: a systematic review and meta-analysis. Lancet. 2010; 375:1545–1555.
2. Williams BG, Gouws E, Boschi-Pinto C, Bryce J, Dye C. Estimates of world-wide distribution of child deaths from acute respiratory infections. Lancet Infect Dis. 2002; 2:25–32.
3. Bryce J, Boschi-Pinto C, Shibuya K, Black RE. WHO estimates of the causes of death in children. Lancet. 2005; 365:1147–1152.
4. Hall CB, Weinberg GA, Iwane MK, et al. The burden of respiratory syncytial virus infection in young children. N Engl J Med. 2009; 360:588–598.
5. Breiman RF, Van Beneden CA, Farnon EC. Surveillance for respiratory infections in low- and middle-income countries: experience from the Centers for Disease Control and Prevention's Global Disease Detection International Emerging Infections Program. J Infect Dis. 2013; 208 Suppl 3:S167–S172.
6. Modjarrad K, Giersing B, Kaslow DC, Smith PG, Moorthy VS. WHO consultation on Respiratory Syncytial Virus Vaccine Development Report from a World Health Organization Meeting held on 23-24 March 2015. Vaccine. 2016; 34:23–24.
7. PD-VAC W. 2014. Status of Vaccine Research and Development of Vaccines for RSV. World Health Organization.
8. NOVAVAX. 2015. Novavax Announces Positive Top-Line Data from Phase 2 Clinical Trial of RSV F Vaccine to Protect Infants via Maternal Immunization. http://www.prnewswire.com/news-releases/novavax-announces-positive-top-line-data-from-phase-2-clinical-trial-of-rsv-f-vaccine-to-protect-infants-via-maternal-immunization-300149808.html.
9. WorldBank. 2015. Pakistan. Accessed Sep 15, 2015 from: http://www.worldbank.org/en/country/pakistan.
10. Mentel R, Wegner U, Bruns R, Gurtler L. Real-time PCR to improve the diagnosis of respiratory syncytial virus infection. J Med Microbiol. 2003; 52:893–896.
11. John TJ, Cherian T, Steinhoff MC, Simoes EA, John M. Etiology of acute respiratory infections in children in tropical southern India. Rev Infect Dis. 1991; 13 Suppl 6:S463–S469.
12. Khor CS, Sam IC, Hooi PS, Quek KF, Chan YF. Epidemiology and seasonality of respiratory viral infections in hospitalized children in Kuala Lumpur, Malaysia: a retrospective study of 27 years. BMC Pediatr. 2012; 12:32.
13. Naorat S, Chittaganpitch M, Thamthitiwat S, et al. Hospitalizations for acute lower respiratory tract infection due to respiratory syncytial virus in Thailand, 2008-2011. J Infect Dis. 2013; 208 Suppl 3:2008–-2011.
14. Ali SA, Khowaja AR, Bashir MZ, Aziz F, Mustafa S, Zaidi A. Role of human metapneumovirus, influenza a virus and respiratory syncytial virus in causing WHO-Defined severe pneumonia in children in a developing country. PLoS ONE. 2013; 8:e74756. https://doi.org/10.1371/journal.pone.0074756.
15. Tariq WU, Waqar T, Ali S, Ghani E. Winter peak of respiratory syncytial virus in Islamabad. Trop Doct. 2005; 35:28–29.
16. Weber MW, Mulholland EK, Greenwood BM. Respiratory syncytial virus infection in tropical and developing countries. Trop Med Int Health. 1998; 3:268–280.