A conformational switch regulates the ubiquitin ligase HUWE1

eLife

Volumn 6, Issue , 2017, Pages

  Sander, Bodo ^a   Xu, Wenshan ^b,c   Eilers, Martin ^b,d   Popov, Nikita ^b,c   Lorenz, Sonja ^a  

^a UNIVERSITY OF WÜRZBURG   (Germany)

^b Comprehensive Cancer Center Mainfranken ^*  (Germany)

^c UNIVERSITY HOSPITAL WÜRZBURG   (Germany)

^d UNIVERSITY OF WÜRZBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

UBIQUITIN LIGASE HUWE1; UBIQUITIN PROTEIN LIGASE; UNCLASSIFIED DRUG; CYCLIN DEPENDENT KINASE INHIBITOR 2A; HUWE1 PROTEIN, HUMAN; PROTEIN BINDING;

ANISOTROPY; AREA UNDER THE CURVE; ARTICLE; CARCINOGENESIS; CHEMICAL PHENOMENA; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; CRYSTALLOGRAPHY; DIMERIZATION; EQUILIBRIUM DIALYSIS; FLUORESCENCE; FLUORESCENCE POLARIZATION; GENE AMPLIFICATION; GENE MUTATION; HUMAN; HYDROGEN BOND; LIGHT SCATTERING; NONHUMAN; POINT MUTATION; POLARIZATION AND DEPOLARIZATION; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; SIZE EXCLUSION CHROMATOGRAPHY; STRUCTURAL BIOINFORMATICS; UBIQUITINATION; ULTRACENTRIFUGATION; CHEMISTRY; METABOLISM; MOLECULAR MODEL; PROTEIN CONFORMATION; PROTEIN MULTIMERIZATION; X RAY CRYSTALLOGRAPHY;

CRYSTALLOGRAPHY, X-RAY; HUMANS; MODELS, MOLECULAR; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN MULTIMERIZATION; TUMOR SUPPRESSOR PROTEIN P14ARF; UBIQUITIN-PROTEIN LIGASES;

EID: 85013434246     PISSN: None     EISSN: 2050084X     Source Type: Journal    
DOI: 10.7554/eLife.21036     Document Type: Article

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