Early treatment with losartan effectively ameliorates hypertension and improves vascular remodeling and function in a prehypertensive rat model

Life Sciences

Volumn 173, Issue , 2017, Pages 20-27

  He, De Hua ^a   Lin, Jin Xiu ^b   Zhang, Liang Min ^c   Xu, Chang Sheng ^d   Xie, Qiang ^a  

^a THE FIRST AFFILIATED HOSPITAL OF XIAMEN UNIVERSITY   (China)

^b FUJIAN MEDICAL UNIVERSITY   (China)

^c People's Hospital of Ningdu County   (China)

^d Fujian Institute of Hypertension   (China)

Author keywords

Amlodipine; Blood pressure; Losartan; Prehypertension; Vascular

Indexed keywords

ALDOSTERONE; AMLODIPINE; ANGIOTENSIN 1 RECEPTOR; ANGIOTENSIN 2 RECEPTOR; ANGIOTENSIN II; LOSARTAN; SODIUM CHLORIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD VESSEL WALL; CONTROLLED STUDY; DRUG EFFICACY; MALE; NONHUMAN; PREHYPERTENSION; PROTEIN EXPRESSION; RADIOIMMUNOASSAY; RAT; RAT MODEL; RESISTANCE BLOOD VESSEL; SYSTOLIC BLOOD PRESSURE; VASCULAR REMODELING; VASCULAR RING; WESTERN BLOTTING; ANIMAL; BIOSYNTHESIS; BLOOD PRESSURE; DISEASE MODEL; DRUG EFFECTS; GENE EXPRESSION REGULATION; HYPERTENSION; METABOLISM; PATHOPHYSIOLOGY; SPONTANEOUSLY HYPERTENSIVE RAT; WISTAR KYOTO RAT;

ALDOSTERONE; ANGIOTENSIN II; ANIMALS; BLOOD PRESSURE; DISEASE MODELS, ANIMAL; GENE EXPRESSION REGULATION; HYPERTENSION; LOSARTAN; MALE; RATS; RATS, INBRED SHR; RATS, INBRED WKY; RECEPTOR, ANGIOTENSIN, TYPE 1; RECEPTOR, ANGIOTENSIN, TYPE 2; VASCULAR REMODELING;

EID: 85013308879     PISSN: 00243205     EISSN: 18790631     Source Type: Journal    
DOI: 10.1016/j.lfs.2017.01.013     Document Type: Article

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