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Volumn 78, Issue 1, 2017, Pages e48-e58

The association between antenatal exposure to selective serotonin reuptake inhibitors and autism: A systematic review and meta-analysis

Author keywords

Antidepressants; Autism; Women's mental health

Indexed keywords

SEROTONIN UPTAKE INHIBITOR;

EID: 85012916973     PISSN: 01606689     EISSN: None     Source Type: Journal    
DOI: 10.4088/JCP.15r10194     Document Type: Review
Times cited : (57)

References (48)
  • 1
    • 84881501823 scopus 로고    scopus 로고
    • Fifth Edition. Washington, DC: American Psychiatric Association
    • American Psychiatric Association. Diagnostic and Statistical Manual for Mental Disorders. Fifth Edition. Washington, DC: American Psychiatric Association; 2013.
    • (2013) Diagnostic and Statistical Manual for Mental Disorders
  • 2
    • 84898957499 scopus 로고    scopus 로고
    • Prevalence of autism spectrum disorder among children aged 8 years-autism and developmental disabilities monitoring network, 11 sites, United States, 2010
    • Developmental Disabilities Monitoring Network Surveillance Year 2010 Principal Investigators; Centers for Disease Control and Prevention (CDC). Prevalence of autism spectrum disorder among children aged 8 years-Autism and Developmental Disabilities Monitoring Network, 11 sites, United States, 2010. MMWR Surveill Summ. 2014;63(2):1-21.
    • (2014) MMWR Surveill Summ. , vol.63 , Issue.2 , pp. 1-21
  • 3
    • 84879217408 scopus 로고    scopus 로고
    • Serotonin hypothesis of autism: Implications for selective serotonin reuptake inhibitor use during pregnancy
    • Harrington RA, Lee LC, Crum RM, et al. Serotonin hypothesis of autism: implications for selective serotonin reuptake inhibitor use during pregnancy. Autism Res. 2013;6(3):149-168.
    • (2013) Autism Res. , vol.6 , Issue.3 , pp. 149-168
    • Harrington, R.A.1    Lee, L.C.2    Crum, R.M.3
  • 4
    • 38549142411 scopus 로고    scopus 로고
    • Use of antidepressant medications during pregnancy: A multisite study
    • Andrade SE, Raebel MA, Brown J, et al. Use of antidepressant medications during pregnancy: a multisite study. Am J Obstet Gynecol. 2008;198(2):194.e1-194.e5.
    • (2008) Am J Obstet Gynecol. , vol.198 , Issue.2 , pp. e1-e5
    • Andrade, S.E.1    Raebel, M.A.2    Brown, J.3
  • 5
    • 79955447412 scopus 로고    scopus 로고
    • A transient placental source of serotonin for the fetal forebrain
    • Bonnin A, Goeden N, Chen K, et al. A transient placental source of serotonin for the fetal forebrain. Nature. 2011;472(7343):347-350.
    • (2011) Nature , vol.472 , Issue.7343 , pp. 347-350
    • Bonnin, A.1    Goeden, N.2    Chen, K.3
  • 6
    • 0028148795 scopus 로고
    • Effects of gestational exposure to monoamine oxidase inhibitors in rats: Preliminary behavioral and neurochemical studies
    • Whitaker-Azmitia PM, Zhang X, Clarke C. Effects of gestational exposure to monoamine oxidase inhibitors in rats: preliminary behavioral and neurochemical studies. Neuropsychopharmacology. 1994;11(2):125-132.
    • (1994) Neuropsychopharmacology , vol.11 , Issue.2 , pp. 125-132
    • Whitaker-Azmitia, P.M.1    Zhang, X.2    Clarke, C.3
  • 7
    • 77951023387 scopus 로고    scopus 로고
    • Serotonin, pregnancy and increased autism prevalence: Is there a link?
    • Hadjikhani N. Serotonin, pregnancy and increased autism prevalence: is there a link? Med Hypotheses. 2010;74(5):880-883.
    • (2010) Med Hypotheses , vol.74 , Issue.5 , pp. 880-883
    • Hadjikhani, N.1
  • 8
    • 80054987375 scopus 로고    scopus 로고
    • Prevalence and correlates of major depressive episode in pregnant and postpartum women in the United States
    • Le Strat Y, Dubertret C, Le Foll B. Prevalence and correlates of major depressive episode in pregnant and postpartum women in the United States. J Affect Disord. 2011;135(1-3):128-138.
    • (2011) J Affect Disord. , vol.135 , Issue.1-3 , pp. 128-138
    • Le-Strat, Y.1    Dubertret, C.2    Le-Foll, B.3
  • 9
    • 84916927662 scopus 로고    scopus 로고
    • Decisional conflict among women considering antidepressant medication use in pregnancy
    • Walton GD, Ross LE, Stewart DE, et al. Decisional conflict among women considering antidepressant medication use in pregnancy. Arch Women Ment Health. 2014;17(6):493-501.
    • (2014) Arch Women Ment Health , vol.17 , Issue.6 , pp. 493-501
    • Walton, G.D.1    Ross, L.E.2    Stewart, D.E.3
  • 10
    • 84929863817 scopus 로고    scopus 로고
    • Prenatal antidepressant exposure is associated with risk for attention-deficit hyperactivity disorder but not autism spectrum disorder in a large health system
    • Clements CC, Castro VM, Blumenthal SR, et al. Prenatal antidepressant exposure is associated with risk for attention-deficit hyperactivity disorder but not autism spectrum disorder in a large health system. Mol Psychiatry. 2015;20(6):727-734.
    • (2015) Mol Psychiatry , vol.20 , Issue.6 , pp. 727-734
    • Clements, C.C.1    Castro, V.M.2    Blumenthal, S.R.3
  • 11
    • 80051631127 scopus 로고    scopus 로고
    • Antidepressant use during pregnancy and childhood autism spectrum disorders
    • Croen LA, Grether JK, Yoshida CK, et al. Antidepressant use during pregnancy and childhood autism spectrum disorders. Arch Gen Psychiatry. 2011;68(11):1104-1112.
    • (2011) Arch Gen Psychiatry , vol.68 , Issue.11 , pp. 1104-1112
    • Croen, L.A.1    Grether, J.K.2    Yoshida, C.K.3
  • 12
    • 84890423003 scopus 로고    scopus 로고
    • Use of selective serotonin reuptake inhibitors during pregnancy and risk of autism
    • Hviid A, Melbye M, Pasternak B. Use of selective serotonin reuptake inhibitors during pregnancy and risk of autism. N Engl J Med. 2013;369(25):2406-2415.
    • (2013) N Engl J Med. , vol.369 , Issue.25 , pp. 2406-2415
    • Hviid, A.1    Melbye, M.2    Pasternak, B.3
  • 13
    • 84920903484 scopus 로고    scopus 로고
    • Exposure to selective serotonin reuptake inhibitors during pregnancy and risk of autism spectrum disorder in children: A systematic review and meta-analysis of observational studies
    • Man KK, Tong HH, Wong LY, et al. Exposure to selective serotonin reuptake inhibitors during pregnancy and risk of autism spectrum disorder in children: a systematic review and meta-analysis of observational studies. Neurosci Biobehav Rev. 2015;49:82-89.
    • (2015) Neurosci Biobehav Rev. , vol.49 , pp. 82-89
    • Man, K.K.1    Tong, H.H.2    Wong, L.Y.3
  • 14
    • 84929322302 scopus 로고    scopus 로고
    • Prenatal antidepressant exposure and the risk of autism spectrum disorders in children: Are we looking at the fall of Gods?
    • Gentile S. Prenatal antidepressant exposure and the risk of autism spectrum disorders in children: are we looking at the fall of Gods? J Affect Disord. 2015;182:132-137.
    • (2015) J Affect Disord. , vol.182 , pp. 132-137
    • Gentile, S.1
  • 15
    • 66149160394 scopus 로고    scopus 로고
    • Major depression and antidepressant treatment: Impact on pregnancy and neonatal outcomes
    • Wisner KL, Sit DK, Hanusa BH, et al. Major depression and antidepressant treatment: impact on pregnancy and neonatal outcomes. Am J Psychiatry. 2009;166(5):557-566.
    • (2009) Am J Psychiatry , vol.166 , Issue.5 , pp. 557-566
    • Wisner, K.L.1    Sit, D.K.2    Hanusa, B.H.3
  • 16
    • 84859574757 scopus 로고    scopus 로고
    • Intellectual disability and major psychiatric disorders: A continuum of neurodevelopmental causality
    • Owen MJ. Intellectual disability and major psychiatric disorders: a continuum of neurodevelopmental causality. Br J Psychiatry. 2012;200(4):268-269.
    • (2012) Br J Psychiatry , vol.200 , Issue.4 , pp. 268-269
    • Owen, M.J.1
  • 17
    • 68049122102 scopus 로고    scopus 로고
    • Preferred reporting items for systematic reviews and meta-analyses: The PRISMA statement
    • Moher D, Liberati A, Tetzlaff J, et al; PRISMA Group. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. PLoS Med. 2009;6(7):e1000097.
    • (2009) PLoS Med. , vol.6 , Issue.7 , pp. e1000097
    • Moher, D.1    Liberati, A.2    Tetzlaff, J.3
  • 18
    • 35248892046 scopus 로고    scopus 로고
    • The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: Guidelines for reporting observational studies
    • von Elm E, Altman DG, Egger M, et al; STROBE Initiative. The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement: guidelines for reporting observational studies. Prev Med. 2007;45(4):247-251.
    • (2007) Prev Med. , vol.45 , Issue.4 , pp. 247-251
    • Von-Elm, E.1    Altman, D.G.2    Egger, M.3
  • 19
    • 82155192831 scopus 로고    scopus 로고
    • Quality assessment of observational studies in psychiatry: An example from perinatal psychiatric research
    • Ross LE, Grigoriadis S, Mamisashvili L, et al. Quality assessment of observational studies in psychiatry: an example from perinatal psychiatric research. Int J Methods Psychiatr Res. 2011;20(4):224-234.
    • (2011) Int J Methods Psychiatr Res. , vol.20 , Issue.4 , pp. 224-234
    • Ross, L.E.1    Grigoriadis, S.2    Mamisashvili, L.3
  • 20
    • 0031754739 scopus 로고    scopus 로고
    • The feasibility of creating a checklist for the assessment of the methodological quality both of randomised and non-randomised studies of health care interventions
    • Downs SH, Black N. The feasibility of creating a checklist for the assessment of the methodological quality both of randomised and non-randomised studies of health care interventions. J Epidemiol Community Health. 1998;52(6):377-384.
    • (1998) J Epidemiol Community Health , vol.52 , Issue.6 , pp. 377-384
    • Downs, S.H.1    Black, N.2
  • 22
    • 67650869592 scopus 로고    scopus 로고
    • Prenatal risk factors for autism: Comprehensive metaanalysis
    • Gardener H, Spiegelman D, Buka SL. Prenatal risk factors for autism: comprehensive metaanalysis. Br J Psychiatry. 2009;195(1):7-14.
    • (2009) Br J Psychiatry , vol.195 , Issue.1 , pp. 7-14
    • Gardener, H.1    Spiegelman, D.2    Buka, S.L.3
  • 23
    • 43049113533 scopus 로고    scopus 로고
    • GRADE: An emerging consensus on rating quality of evidence and strength of recommendations
    • Guyatt GH, Oxman AD, Vist GE, et al; GRADE Working Group. GRADE: an emerging consensus on rating quality of evidence and strength of recommendations. BMJ. 2008;336(7650):924-926.
    • (2008) BMJ , vol.336 , Issue.7650 , pp. 924-926
    • Guyatt, G.H.1    Oxman, A.D.2    Vist, G.E.3
  • 24
    • 84892691480 scopus 로고    scopus 로고
    • Prenatal exposure to antidepressants and persistent pulmonary hypertension of the newborn: Systematic review and meta-analysis
    • Grigoriadis S, Vonderporten EH, Mamisashvili L, et al. Prenatal exposure to antidepressants and persistent pulmonary hypertension of the newborn: systematic review and meta-analysis. BMJ. 2014;348:f6932.
    • (2014) BMJ , vol.348 , pp. f6932
    • Grigoriadis, S.1    Vonderporten, E.H.2    Mamisashvili, L.3
  • 25
    • 0022992740 scopus 로고
    • Meta-analysis in clinical trials
    • Der Simonian R, Laird N. Meta-analysis in clinical trials. Control Clin Trials. 1986;7(3):177-188.
    • (1986) Control Clin Trials , vol.7 , Issue.3 , pp. 177-188
    • Der Simonian, R.1    Laird, N.2
  • 26
    • 33745700802 scopus 로고    scopus 로고
    • Assessing heterogeneity in meta-analysis: Q statistic or I2 index?
    • Huedo-Medina TB, Sánchez-Meca J, Marín-Martínez F, et al. Assessing heterogeneity in meta-analysis: Q statistic or I2 index? Psychol Methods. 2006;11(2):193-206.
    • (2006) Psychol Methods , vol.11 , Issue.2 , pp. 193-206
    • Huedo-Medina, T.B.1    Sánchez-Meca, J.2    Marín-Martínez, F.3
  • 27
    • 84905114793 scopus 로고    scopus 로고
    • Prenatal exposure to selective serotonin reuptake inhibitors and social responsiveness symptoms of autism: Population-based study of young children
    • El Marroun H, White TJ, van der Knaap NJ, et al. Prenatal exposure to selective serotonin reuptake inhibitors and social responsiveness symptoms of autism: population-based study of young children. Br J Psychiatry. 2014;205(2):95-102.
    • (2014) Br J Psychiatry , vol.205 , Issue.2 , pp. 95-102
    • El-Marroun, H.1    White, T.J.2    Van-Der-Knaap, N.J.3
  • 28
    • 84912027605 scopus 로고    scopus 로고
    • In utero exposure to selective serotonin reuptake inhibitors and risk for autism spectrum disorder
    • Gidaya NB, Lee BK, Burstyn I, et al. In utero exposure to selective serotonin reuptake inhibitors and risk for autism spectrum disorder. J Autism Dev Disord. 2014;44(10):2558-2567.
    • (2014) J Autism Dev Disord. , vol.44 , Issue.10 , pp. 2558-2567
    • Gidaya, N.B.1    Lee, B.K.2    Burstyn, I.3
  • 29
    • 84887774748 scopus 로고    scopus 로고
    • Antidepressant exposure in pregnancy and risk of autism spectrum disorders
    • Sørensen MJ, Grønborg TK, Christensen J, et al. Antidepressant exposure in pregnancy and risk of autism spectrum disorders. Clin Epidemiol. 2013;5(1):449-459.
    • (2013) Clin Epidemiol. , vol.5 , Issue.1 , pp. 449-459
    • Sørensen, M.J.1    Grønborg, T.K.2    Christensen, J.3
  • 30
    • 84899789470 scopus 로고    scopus 로고
    • Prenatal SSRI use and offspring with autism spectrum disorder or developmental delay
    • Harrington RA, Lee LC, Crum RM, et al. Prenatal SSRI use and offspring with autism spectrum disorder or developmental delay. Pediatrics. 2014;133(5):e1241-e1248.
    • (2014) Pediatrics , vol.133 , Issue.5 , pp. e1241-e1248
    • Harrington, R.A.1    Lee, L.C.2    Crum, R.M.3
  • 31
    • 84878304990 scopus 로고    scopus 로고
    • Parental depression, maternal antidepressant use during pregnancy, and risk of autism spectrum disorders: Population based casecontrol study
    • Rai D, Lee BK, Dalman C, et al. Parental depression, maternal antidepressant use during pregnancy, and risk of autism spectrum disorders: population based casecontrol study. BMJ. 2013;346:f2059.
    • (2013) BMJ , vol.346 , pp. f2059
    • Rai, D.1    Lee, B.K.2    Dalman, C.3
  • 32
    • 84956894014 scopus 로고    scopus 로고
    • Antidepressant use during pregnancy and the risk of autism spectrum disorder in children
    • Boukhris T, Sheehy O, Mottron L, et al. Antidepressant use during pregnancy and the risk of autism spectrum disorder in children. JAMA Pediatr. 2016;170(2):117-124.
    • (2016) JAMA Pediatr. , vol.170 , Issue.2 , pp. 117-124
    • Boukhris, T.1    Sheehy, O.2    Mottron, L.3
  • 33
    • 0035961567 scopus 로고    scopus 로고
    • A comparison of methods to detect publication bias in meta-analysis
    • Macaskill P, Walter SD, Irwig L. A comparison of methods to detect publication bias in meta-analysis. Stat Med. 2001;20(4):641-654.
    • (2001) Stat Med. , vol.20 , Issue.4 , pp. 641-654
    • Macaskill, P.1    Walter, S.D.2    Irwig, L.3
  • 34
    • 84876296688 scopus 로고    scopus 로고
    • Identification of risk loci with shared effects on five major psychiatric disorders: A genome-wide analysis
    • Cross-Disorder Group of the Psychiatric Genomics Consortium. Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis. Lancet. 2013;381(9875):1371-1379.
    • (2013) Lancet , vol.381 , Issue.9875 , pp. 1371-1379
  • 35
    • 0036673539 scopus 로고    scopus 로고
    • Depression in persons with autism: Implications for research and clinical care
    • Ghaziuddin M, Ghaziuddin N, Greden J. Depression in persons with autism: implications for research and clinical care. J Autism Dev Disord. 2002;32(4):299-306.
    • (2002) J Autism Dev Disord. , vol.32 , Issue.4 , pp. 299-306
    • Ghaziuddin, M.1    Ghaziuddin, N.2    Greden, J.3
  • 36
    • 0037464828 scopus 로고    scopus 로고
    • Obsessive-compulsive behaviors in parents of multiplex autism families
    • Hollander E, King A, Delaney K, et al. Obsessive-compulsive behaviors in parents of multiplex autism families. Psychiatry Res. 2003;117(1):11-16.
    • (2003) Psychiatry Res. , vol.117 , Issue.1 , pp. 11-16
    • Hollander, E.1    King, A.2    Delaney, K.3
  • 37
    • 2342445234 scopus 로고    scopus 로고
    • Autism and familial major mood disorder: Are they related?
    • De Long R. Autism and familial major mood disorder: are they related? J Neuropsychiatry Clin Neurosci. 2004;16(2):199-213.
    • (2004) J Neuropsychiatry Clin Neurosci. , vol.16 , Issue.2 , pp. 199-213
    • De Long, R.1
  • 38
    • 0042844766 scopus 로고    scopus 로고
    • Divalproex in the treatment of impulsive aggression: Efficacy in cluster B personality disorders
    • Hollander E, Tracy KA, Swann AC, et al. Divalproex in the treatment of impulsive aggression: efficacy in cluster B personality disorders. Neuropsychopharmacology. 2003;28(6):1186-1197.
    • (2003) Neuropsychopharmacology , vol.28 , Issue.6 , pp. 1186-1197
    • Hollander, E.1    Tracy, K.A.2    Swann, A.C.3
  • 39
    • 0028658289 scopus 로고
    • Psychobiological influences of stress and HPA regulation on the human fetus and infant birth outcomes
    • Sandman CA, Wadhwa PD, Dunkel-Schetter C, et al. Psychobiological influences of stress and HPA regulation on the human fetus and infant birth outcomes. Ann N Y Acad Sci. 1994;739:198-210.
    • (1994) Ann N Y Acad Sci. , vol.739 , pp. 198-210
    • Sandman, C.A.1    Wadhwa, P.D.2    Dunkel-Schetter, C.3
  • 40
    • 84875500069 scopus 로고    scopus 로고
    • O-GlcNAc transferase (OGT) as a placental biomarker of maternal stress and reprogramming of CNS gene transcription in development
    • Howerton CL, Morgan CP, Fischer DB, et al. O-GlcNAc transferase (OGT) as a placental biomarker of maternal stress and reprogramming of CNS gene transcription in development. Proc Natl Acad Sci U S A. 2013;110(13):5169-5174.
    • (2013) Proc Natl Acad Sci U S A , vol.110 , Issue.13 , pp. 5169-5174
    • Howerton, C.L.1    Morgan, C.P.2    Fischer, D.B.3
  • 42
    • 33646494605 scopus 로고    scopus 로고
    • Of minds and embryos: Left-right asymmetry and the serotonergic controls of pre-neural morphogenesis
    • Levin M, Buznikov GA, Lauder JM. Of minds and embryos: left-right asymmetry and the serotonergic controls of pre-neural morphogenesis. Dev Neurosci. 2006;28(3):171-185.
    • (2006) Dev Neurosci. , vol.28 , Issue.3 , pp. 171-185
    • Levin, M.1    Buznikov, G.A.2    Lauder, J.M.3
  • 43
    • 0033798308 scopus 로고    scopus 로고
    • Convergence and plasticity of monoaminergic systems in the medial prefrontal cortex during the postnatal period: Implications for the development of psychopathology
    • Benes FM, Taylor JB, Cunningham MC. Convergence and plasticity of monoaminergic systems in the medial prefrontal cortex during the postnatal period: implications for the development of psychopathology. Cereb Cortex. 2000;10(10):1014-1027.
    • (2000) Cereb Cortex. , vol.10 , Issue.10 , pp. 1014-1027
    • Benes, F.M.1    Taylor, J.B.2    Cunningham, M.C.3
  • 44
    • 34447636274 scopus 로고    scopus 로고
    • Embryonic depletion of serotonin affects cortical development
    • Vitalis T, Cases O, Passemard S, et al. Embryonic depletion of serotonin affects cortical development. Eur J Neurosci. 2007;26(2):331-344.
    • (2007) Eur J Neurosci. , vol.26 , Issue.2 , pp. 331-344
    • Vitalis, T.1    Cases, O.2    Passemard, S.3
  • 45
    • 0000526929 scopus 로고
    • Studies on 5-hydroxyindole metabolism in autistic and other mentally retarded children
    • Schain RJ, Freedman DX. Studies on 5-hydroxyindole metabolism in autistic and other mentally retarded children. J Pediatr. 1961;58(3):315-320.
    • (1961) J Pediatr. , vol.58 , Issue.3 , pp. 315-320
    • Schain, R.J.1    Freedman, D.X.2
  • 46
    • 2942748505 scopus 로고    scopus 로고
    • Platelet serotonin levels in pervasive developmental disorders and mental retardation: Diagnostic group differences, within-group distribution, and behavioral correlates
    • Mulder EJ, Anderson GM, Kema IP, et al. Platelet serotonin levels in pervasive developmental disorders and mental retardation: diagnostic group differences, within-group distribution, and behavioral correlates. J Am Acad Child Adolesc Psychiatry. 2004;43(4):491-499.
    • (2004) J Am Acad Child Adolesc Psychiatry , vol.43 , Issue.4 , pp. 491-499
    • Mulder, E.J.1    Anderson, G.M.2    Kema, I.P.3
  • 47
    • 79952536293 scopus 로고    scopus 로고
    • Fetal exposure to teratogens: Evidence of genes involved in autism
    • Dufour-Rainfray D, Vourc'h P, Tourlet S, et al. Fetal exposure to teratogens: evidence of genes involved in autism. Neurosci Biobehav Rev. 2011;35(5):1254-1265.
    • (2011) Neurosci Biobehav Rev. , vol.35 , Issue.5 , pp. 1254-1265
    • Dufour-Rainfray, D.1    Vourc'H, P.2    Tourlet, S.3
  • 48
    • 33846449085 scopus 로고    scopus 로고
    • Treatment with antidepressant medications in private health plans
    • Larson MJ, Miller K, Fleming KJ. Treatment with antidepressant medications in private health plans. Adm Policy Ment Health. 2007;34(2):116-126.
    • (2007) Adm Policy Ment Health , vol.34 , Issue.2 , pp. 116-126
    • Larson, M.J.1    Miller, K.2    Fleming, K.J.3


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