Calcium/calmodulin-dependent kinase II inhibition in smooth muscle reduces angiotensin II-induced hypertension by controlling aortic remodeling and baroreceptor function

Journal of the American Heart Association

Volumn 4, Issue 6, 2015, Pages e001949-

  Prasad, Anand M ^a   Morgan, Donald A ^a   Nuno, Daniel W ^a   Ketsawatsomkron, Pimonrat ^a   Bair, Thomas B ^a   Venema, Ashlee N ^a   Dibbern, Megan E ^a   Kutschke, William J ^a   Weiss, Robert M ^a   Lamping, Kathryn G ^a   Chapleau, Mark W ^a   Sigmund, Curt D ^a   Rahmouni, Kamal ^a   Grumbach, Isabella M ^a  

^a UNIVERSITY OF IOWA   (United States)

Author keywords

angiotensin II; calcium calmodulin dependent kinase II; hypertension; sympathetic nerve activity; vascular remodeling

Indexed keywords

ANGIOTENSIN II; ANTIHYPERTENSIVE AGENT; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II; NORADRENALIN;

ANIMAL; ANTAGONISTS AND INHIBITORS; AORTA; BLOOD; C57BL MOUSE; CHEMICALLY INDUCED; DNA MICROARRAY; DRUG EFFECTS; ECHOCARDIOGRAPHY; HYPERTENSION; METABOLISM; MOUSE; PATHOPHYSIOLOGY; PHYSIOLOGY; PRESSORECEPTOR; TRANSGENIC MOUSE; VASCULAR REMODELING; VASCULAR SMOOTH MUSCLE;

ANGIOTENSIN II; ANIMALS; ANTIHYPERTENSIVE AGENTS; AORTA; CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 2; ECHOCARDIOGRAPHY; HYPERTENSION; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MUSCLE, SMOOTH, VASCULAR; NOREPINEPHRINE; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PRESSORECEPTORS; VASCULAR REMODELING;

EID: 85012821819     PISSN: None     EISSN: 20479980     Source Type: Journal    
DOI: 10.1161/JAHA.115.001949     Document Type: Article

References (0)