Direct-acting antiviral therapy for hepatitis E virus?

The Lancet Gastroenterology and Hepatology

Volumn 2, Issue 3, 2017, Pages 154-155

  Kamar, Nassim ^a   Wang, Wenshi ^b   Dalton, Harry R ^c   Pan, Qiuwei ^b  

^a UNIVERSITÉ PAUL SABATIER   (France)

^b ERASMUS MEDICAL CENTER   (Netherlands)

^c UNIVERSITY OF EXETER MEDICAL SCHOOL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

RIBAVIRIN; RNA POLYMERASE; SOFOSBUVIR; ANTIVIRUS AGENT;

ANTIVIRAL THERAPY; CHRONIC HEPATITIS; HEPATITIS C VIRUS GENOTYPE 3; HEPATITIS E VIRUS; KIDNEY INJURY; LETTER; LIVER CIRRHOSIS; MUTATION; NONHUMAN; PRIORITY JOURNAL; STEM CELL TRANSPLANTATION; VIRUS REPLICATION; CHRONIC HEPATITIS C; COMBINATION DRUG THERAPY; DRUG EFFECTS; HEPACIVIRUS; HEPATITIS B; HEPATITIS B VIRUS; HEPATITIS C; HEPATITIS E; HUMAN; VIRUS ACTIVATION;

ANTIVIRAL AGENTS; DRUG THERAPY, COMBINATION; HEPACIVIRUS; HEPATITIS B; HEPATITIS B VIRUS; HEPATITIS C; HEPATITIS C, CHRONIC; HEPATITIS E; HEPATITIS E VIRUS; HUMANS; VIRUS ACTIVATION;

EID: 85012257332     PISSN: 24681253     EISSN: None     Source Type: Journal    
DOI: 10.1016/S2468-1253(16)30242-4     Document Type: Letter

References (5)

1. 1 The Lancet Gastroenterology & Hepatology. Hepatitis E: a neglected virus. Lancet Gastroenterol Hepatol, 1, 2016, 261.
2. 2 Dao Thi, VL, Debing, Y, Wu, X, et al. Sofosbuvir inhibits hepatitis E virus replication in vitro and results in an additive effect when combined with ribavirin. Gastroenterology 150 (2016), 82–85.
3. 3 Wang, W, Hakim, MS, Nair, VP, et al. Distinct antiviral potency of sofosbuvir against hepatitis C and E viruses. Gastroenterology 151 (2016), 1251–1253.
4. 4 van der Valk, M, Zaaijer, HL, Kater, AP, Schinkel, J, Sofosbuvir shows antiviral activity in a patient with chronic hepatitis E virus infection. J Hepatol 66 (2017), 242–243.
5. 5 Donnelly, MC, Imlach, SN, Abravanel, F, et al. Sofosbuvir and daclatasvir anti-viral therapy fails to clear HEV viremia and restore reactive T cells in a HEV/HCV co-infected liver transplant recipient. Gastroenterology 152 (2017), 300–301.