Analgesic and Sensory Effects of the Pecs Local Anesthetic Block in Patients with Persistent Pain after Breast Cancer Surgery: A Pilot Study

Pain Practice

Volumn 17, Issue 2, 2017, Pages 185-191

  Wijayasinghe, Nelun ^a   Andersen, Kenneth G ^a   Kehlet, Henrik ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

breast cancer surgery; neuropathic pain; pecs nerve block; pectoral nerves; persistent pain; postoperative pain; PPBCS

Indexed keywords

BUPIVACAINE; LOCAL ANESTHETIC AGENT;

ADULT; AGED; ANALGESIC ACTIVITY; ARTICLE; BREAST CANCER; CANCER SURGERY; CLINICAL ARTICLE; FEMALE; HUMAN; HYPESTHESIA; MIDDLE AGED; NERVE BLOCK; NEUROPATHIC PAIN; PAIN INTENSITY; PECTORAL NERVE BLOCK; PILOT STUDY; POSTOPERATIVE PAIN; QUANTITATIVE SENSORY TESTING; SENSORY ANALYSIS; SLEEP QUALITY; ANALGESIA; BREAST NEOPLASMS; CHRONIC PAIN; COMPLICATION; DRUG EFFECTS; NERVE; PAIN MEASUREMENT; PAIN, POSTOPERATIVE; PROCEDURES; SENSATION; SLEEP WAKE DISORDERS;

ADULT; AGED; ANALGESIA; ANESTHETICS, LOCAL; BREAST NEOPLASMS; CHRONIC PAIN; FEMALE; HUMANS; MIDDLE AGED; NERVE BLOCK; PAIN MEASUREMENT; PAIN, POSTOPERATIVE; PILOT PROJECTS; SENSATION; SLEEP WAKE DISORDERS; THORACIC NERVES;

EID: 85012225932     PISSN: 15307085     EISSN: 15332500     Source Type: Journal    
DOI: 10.1111/papr.12423     Document Type: Article

References (25)

1. Andersen KG, Kehlet H. Persistent pain after breast cancer treatment: a critical review of risk factors and strategies for prevention. J Pain. 2011;12:725–746.
2. Belfer I, Schreiber KL, Shaffer JR, et al. Persistent postmastectomy pain in breast cancer survivors: analysis of clinical, demographic, and psychosocial factors. J Pain. 2013;14:1185–1195.
3. Mejdahl MK, Andersen KG, Gartner R, Kroman N, Kehlet H. Persistent pain and sensory disturbances after treatment for breast cancer: six year nationwide follow-up study. BMJ. 2013;346:f1865.
4. Jung BF, Ahrendt GM, Oaklander AL, Dworkin RH. Neuropathic pain following breast cancer surgery: proposed classification and research update. Pain. 2003;104:1–13.
5. Schreiber KL, Kehlet H, Belfer I, Edwards RR. Predicting, preventing and managing persistent pain after breast cancer surgery: the importance of psychosocial factors. Pain Manag. 2014;4:445–459.
6. Wijayasinghe N, Andersen KG, Kehlet H. Neural blockade for persistent pain after breast cancer surgery. Reg Anesth Pain Med. 2014;39:272–278.
7. Desroches J, Grabs U, Grabs D. Selective ultrasound guided pectoral nerve targeting in breast augmentation: how to spare the brachial plexus cords? Clin Anat. 2013;26:49–55.
8. Blanco R. The ‘pecs block’: a novel technique for providing analgesia after breast surgery. Anaesthesia. 2011;66:847–848.
9. Blanco R, Fajardo M, Parras MT. Ultrasound description of Pecs II (modified Pecs I): a novel approach to breast surgery. Rev Esp Anestesiol Reanim. 2012;59:470–475.
10. Bashandy GM, Abbas DN. Pectoral nerves I and II blocks in multimodal analgesia for breast cancer surgery: a randomized clinical trial. Reg Anesth Pain Med. 2015;40:68–74.
11. Shin HJ, Shin JC, Kim WS, Chang WH, Lee SC. Application of ultrasound-guided trigger point injection for myofascial trigger points in the subscapularis and pectoralis muscles to post-mastectomy patients: a pilot study. Yonsei Med J. 2014;55:792–799.
12. Vlassakov KV, Narang S, Kissin I. Local anesthetic blockade of peripheral nerves for treatment of neuralgias: systematic analysis. Anesth Analg. 2011;112:1487–1493.
13. Andersen KG, Aasvang EK, Kroman N, Kehlet H. Intercostobrachial nerve handling and pain after axillary lymph node dissection for breast cancer. Acta Anaesthesiol Scand. 2014;58:1240–1248.
14. Andersen KG, Kehlet H, Aasvang EK. Test-retest agreement and reliability of quantitative sensory testing 1 year after breast cancer surgery. Clin J Pain. 2015;31:393–403.
15. Bischoff JM, Koscielniak-Nielsen ZJ, Kehlet H, Werner MU. Ultrasound-guided ilioinguinal/iliohypogastric nerve blocks for persistent inguinal postherniorrhaphy pain: a randomized, double-blind, placebo-controlled, crossover trial. Anesth Analg. 2012;114:1323–1329.
16. Vernon MK, Brandenburg NA, Alvir JM, Griesing T, Revicki DA. Reliability, validity, and responsiveness of the daily sleep interference scale among diabetic peripheral neuropathy and postherpetic neuralgia patients. J Pain Symptom Manage. 2008;36:54–68.
17. Andersen KG, Christensen KB, Kehlet H, Bidstup PE. The effect of pain on physical functioning after breast cancer treatment: development and validation of an assessment tool. Clin J Pain. 2015;31:794–802.
18. Treede RD, Jensen TS, Campbell JN, et al. Neuropathic pain: redefinition and a grading system for clinical and research purposes. Neurology. 2008;70:1630–1635.
19. Andersen KG, Jensen MB, Tvedeskov TF, Kehlet H, Gartner R, Kroman N. Persistent pain, sensory disturbances and functional impairment after immediate or delayed axillary lymph node dissection. Eur J Surg Oncol. 2013;39:31–35.
20. Dworkin RH, Turk DC, Wyrwich KW, et al. Interpreting the clinical importance of treatment outcomes in chronic pain clinical trials: IMMPACT recommendations. J Pain. 2008;9:105–121.
21. Gottrup H, Andersen J, Arendt-Nielsen L, Jensen TS. Psychophysical examination in patients with post-mastectomy pain. Pain. 2000;87:275–284.
22. Vilholm OJ, Cold S, Rasmussen L, Sindrup SH. Sensory function and pain in a population of patients treated for breast cancer. Acta Anaesthesiol Scand. 2009;53:800–806.
23. Gracely RH, Lynch SA, Bennett GJ. Painful neuropathy: altered central processing maintained dynamically by peripheral input. Pain. 1992;51:175–194.
24. Haroutounian S, Nikolajsen L, Bendtsen TF, et al. Primary afferent input critical for maintaining spontaneous pain in peripheral neuropathy. Pain. 2014;155:1272–1279.
25. Arner S, Lindblom U, Meyerson BA, Molander C. Prolonged relief of neuralgia after regional anesthetic blocks. A call for further experimental and systematic clinical studies. Pain. 1990;43:287–297.