Sickle cell trait and interpretation of hemoglobin A1c levels

JAMA - Journal of the American Medical Association

Volumn 317, Issue 5, 2017, Pages 481-482

  Bleyer, Anthony J ^a   Aloi, Joseph A ^a  

^a WAKE FOREST SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; HEMOGLOBIN A1C; GLYCOSYLATED HEMOGLOBIN; HEMOGLOBIN S;

AGE; ANCESTRY GROUP; BLACK PERSON; CAUCASIAN; DIABETES MELLITUS; DIAGNOSTIC ERROR; EDITORIAL; GLUCOSE BLOOD LEVEL; GLUCOSE REGULATION SYSTEM; HEMOGLOBIN BLOOD LEVEL; HUMAN; IMPAIRED GLUCOSE TOLERANCE; IRON DEFICIENCY ANEMIA; ORAL GLUCOSE TOLERANCE TEST; PREVALENCE; RACE DIFFERENCE; SICKLE CELL TRAIT; BLOOD EXAMINATION; SICKLE CELL ANEMIA;

ANEMIA, SICKLE CELL; HEMATOLOGIC TESTS; HEMOGLOBIN A, GLYCOSYLATED; HEMOGLOBIN, SICKLE; HUMANS; SICKLE CELL TRAIT;

EID: 85012024068     PISSN: 00987484     EISSN: 15383598     Source Type: Journal    
DOI: 10.1001/jama.2016.20994     Document Type: Editorial

References (12)

1. Bleyer AJ, Vidya S, Sujata L, et al. The impact of sickle cell trait on glycated hemoglobin in diabetes mellitus. Diabet Med. 2010;27(9):1012-1016.
2. Freedman BI, Shihabi ZK, Andries L, et al. Relationship between assays of glycemia in diabetic subjects with advanced chronic kidney disease. Am J Nephrol. 2010;31(5):375-379.
3. English E, Idris I, Smith G, Dhatariya K, Kilpatrick ES, JohnWG. The effect of anaemia and abnormalities of erythrocyte indices on HbA1c analysis: a systematic review. Diabetologia. 2015;58 (7):1409-1421.
4. Carson AP, Muntner P, Selvin E, et al. Do glycemic marker levels vary by race? differing results from a cross-sectional analysis of individuals with and without diagnosed diabetes. BMJ Open Diabetes Res Care. 2016;4(1):e000213.
5. NGSP. Factors that interfere with HbA1c results. http://www.ngsp.or/factors.asp. Updated April 6, 2016. Accessed January 9, 2017.
6. LacyME,Wellenius GA, Sumner AE, et al. Association of sickle trait with hemoglobin A1c in African Americans. JAMA. doi:10.1001/jama.2016 .21035
7. Rohlfing CL, Little RR, Wiedmeyer HM, et al. Use of GHb (HbA1c) in screening for undiagnosed diabetes in the US population. Diabetes Care. 2000;23(2):187-191.
8. Herman WH, Ma Y, Uwaifo G, et al; Diabetes Prevention Program Research Group. Differences in A1C by race and ethnicity among patients with impaired glucose tolerance in the Diabetes Prevention Program. Diabetes Care. 2007;30(10): 2453-2457.
9. Bleyer AJ, Hire D, Russell GB, et al. Ethnic variation in the correlation between random serum glucose concentration and glycated haemoglobin. Diabet Med. 2009;26(2):128-133.
10. Miller ME, Bonds DE, Gerstein HC, et al; ACCORD Investigators. The effects of baseline characteristics, glycaemia treatment approach, and glycated haemoglobin concentration on the risk of severe hypoglycaemia: post hoc epidemiological analysis of the ACCORD study. BMJ. 2010;340: b5444.
11. Long KA, Thomas SB, Grubs RE, Gettig EA, Krishnamurti L. Attitudes and beliefs of African-Americans toward genetics, genetic testing, and sickle cell disease education and awareness. J Genet Couns. 2011;20(6):572-592.
12. American Diabetes Association. Standards of medical care in diabetes 2017. Diabetes Care. 2017; 40(suppl 1):S1-S135.