Comparative evaluation of four phenotypic tests for detection of carbapenemase-producing gram-negative bacteria

Journal of Clinical Microbiology

Volumn 55, Issue 2, 2017, Pages 510-518

  Noël, Audrey ^a   Huang, Te Din ^a   Berhin, Catherine ^a   Hoebeke, Martin ^a   Bouchahrouf, Warda ^a   Yunus, Sami ^a   Bogaerts, Pierre ^a   Glupczynski, Youri ^a  

^a CHU UCL NAMUR   (Belgium)

Author keywords

Acinetobacter; Antibiotic resistance; Carbapenem hydrolysis; Carbapenemase screening; CPE; Pseudomonas

Indexed keywords

CARBAPENEM; CARBAPENEMASE; ERTAPENEM; IMIPENEM; MEROPENEM; BACTERIAL PROTEIN; BETA LACTAMASE;

ACINETOBACTER; ARTICLE; ASSAY; BACILLI; BACTERIUM DETECTION; BACTERIUM IDENTIFICATION; BETA CARBA TEST; BYG CARBA TEST; CARBAPENEMASE PRODUCING ENTEROBACTERIACEAE; CITROBACTER FREUNDII; CITROBACTER KOSERI; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; COST; DIAGNOSTIC KIT; DIAGNOSTIC TEST; DIAGNOSTIC TEST ACCURACY STUDY; ENTEROBACTER; ENTEROBACTER AEROGENES; ENTEROBACTER ASBURIAE; ENTEROBACTER CLOACAE; ESCHERICHIA COLI; INTERMETHOD COMPARISON; KLEBSIELLA OXYTOCA; KLEBSIELLA PNEUMONIAE; NEO RAPID CARB KIT; NONHUMAN; PREDICTIVE VALUE; PROSPECTIVE STUDY; PSEUDOMONAS; RAPIDEC CARBA NP TEST; SENSITIVITY AND SPECIFICITY; SERRATIA MARCESCENS; TURNAROUND TIME; COMPARATIVE STUDY; ENTEROBACTERIACEAE; ENZYMOLOGY; EVALUATION STUDY; GRAM-NEGATIVE BACTERIAL INFECTIONS; HUMAN; ISOLATION AND PURIFICATION; MASS SCREENING; MICROBIOLOGICAL EXAMINATION; MICROBIOLOGY; PROCEDURES;

ACINETOBACTER; BACTERIAL PROTEINS; BACTERIOLOGICAL TECHNIQUES; BETA-LACTAMASES; ENTEROBACTERIACEAE; GRAM-NEGATIVE BACTERIAL INFECTIONS; HUMANS; MASS SCREENING; PROSPECTIVE STUDIES; PSEUDOMONAS; SENSITIVITY AND SPECIFICITY;

EID: 85011977334     PISSN: 00951137     EISSN: 1098660X     Source Type: Journal    
DOI: 10.1128/JCM.01853-16     Document Type: Article

References (24)

1. Nordmann P, Naas T, Poirel L. 2011. Global spread of carbapenemaseproducing Enterobacteriaceae. Emerg Infect Dis 17:1791-1798. https://doi.org/10.3201/eid1710.110655.
2. Cantón R, Akova M, Carmeli Y, Giske CG, Glupczynski Y, Gniadkowski M, Livermore DM, Miriagou V, Naas T, Rossolini GM, Samuelsen O, Seifert H, Woodford N, Nordmann P. 2012. Rapid evolution and spread of carbapenemases among Enterobacteriaceae in Europe. Clin Microbiol Infect 18:413-431. https://doi.org/10.1111/j.1469-0691.2012.03821.x.
3. Diene SM, Rolain JM. 2014. Carbapenemase genes and genetic platforms in Gram-negative bacilli: Enterobacteriaceae, Pseudomonas and Acinetobacter species. Clin Microbiol Infect 20:831-838. https://doi.org/10.1111/1469-0691.12655.
4. Albiger B, Glasner C, Struelens MJ, Grundmann H, Monnet DL, European Survey of Carbapenemase-Producing Enterobacteriaceae Working Group. 2015. Carbapenemase-producing Enterobacteriaceae in Europe: Assessment by national experts from 38 countries, May 2015. Euro Surveill 20(45):pii-30062. http://www.eurosurveillance.org/ViewArticle.aspx?ArticleId-21300.
5. Kempf M, Rolain JM. 2012. Emergence of resistance to carbapenems in Acinetobacter baumannii in Europe: Clinical impact and therapeutic options. Int J Antimicrob Agents 39:105-114. https://doi.org/10.1016/j.ijantimicag.2011.10.004.
6. Castanheira M, Deshpande LM, Costello A, Davies TA, Jones RN. 2014. Epidemiology and carbapenem resistance mechanisms of carbapenemnon- susceptible Pseudomonas aeruginosa collected during 2009-11 in 14 European and Mediterranean countries. J Antimicrob Chemother 69:1804-1814. https://doi.org/10.1093/jac/dku048.
7. Bogaerts P, Yunus S, Massart M, Huang TD, Glupczynski Y. 2016. Evaluation of the BYG Carba test, a new electrochemical assay for rapid laboratory detection of carbapenemase-producing Enterobacteriaceae. J Clin Microbiol 54:349-358. https://doi.org/10.1128/JCM.02404-15.
8. Huang TD, Berhin C, Bogaerts P, Glupczynski Y. 2014. Comparative evaluation of two chromogenic tests for rapid detection of carbapenemase in Enterobacteriaceae and in Pseudomonas aeruginosa isolates. J Clin Microbiol 52:3060-3063. https://doi.org/10.1128/JCM.00643-14.
9. Poirel L, Nordmann P. 2015. Rapidec Carba NP test for rapid detection of carbapenemase producers. J Clin Microbiol 53:3003-3008. https://doi.org/10.1128/JCM.00977-15.
10. Gallagher LC, Roundtree SS, Lancaster DP, Rudin SD, Bard JD, Roberts AL, Marshall SH, Bonomo RA, Sullivan KV. 2015. Performance of the CLSI Carba NP and the Rosco Carb screen assays using North American carbapenemase-producing Enterobacteriaceae and Pseudomonas aeruginosa isolates. J Clin Microbiol 53:3370-3373. https://doi.org/10.1128/JCM.01547-15.
11. AbdelGhani S, Thomson GK, Snyder JW, Thomson KS. 2015. Comparison of the Carba NP, modified Carba NP, and updated Rosco Neo-Rapid Carb kit tests for carbapenemase detection. J Clin Microbiol 53:3539-3542. https://doi.org/10.1128/JCM.01631-15.
12. Hombach M, von Gunten B, Castelberg C, Bloemberg GV. 2015. Evaluation of the Rapidec Carba NP test for detection of carbapenemases in Enterobacteriaceae. J Clin Microbiol 53:3828-3833. https://doi.org/10.1128/JCM.02327-15.
13. Dortet L, Agathine A, Naas T, Cuzon G, Poirel L, Nordmann P. 2015. Evaluation of the Rapidec Carba NP, the Rapid Carb Screen and the Carba NP test for biochemical detection of carbapenemase-producing Enterobacteriaceae. J Antimicrob Chemother 70:3014-3022. https://doi.org/10.1093/jac/dkv213.
14. Garg A, Garg J, Upadhyay GC, Agarwal A, Bhattacharjee A. 2015. Evaluation of the Rapidec Carba NP test kit for detection of carbapenemaseproducing Gram-negative bacteria. Antimicrob Agents Chemother 59: 7870-7872. https://doi.org/10.1128/AAC.01783-15.
15. Lifshitz Z, Adler A, Carmeli Y. 2016. Comparative study of a novel biochemical assay, the Rapidec Carba NP test, for detecting carbapenemase-producing Enterobacteriaceae. J Clin Microbiol 54: 453-456. https://doi.org/10.1128/JCM.02626-15.
16. Kabir MH, Meunier D, Hopkins KL, Giske CG, Woodford N. 2016. A two-centre evaluation of Rapidec Carba NP for carbapenemase detection in Enterobacteriaceae, Pseudomonas aeruginosa and Acinetobacter spp. J Antimicrob Chemother 71:1213-1216. https://doi.org/10.1093/jac/dkv468.
17. Bogaerts P, Yunus S, Massart M, Huang TD, Glupczynski Y. 2016. Validation of the BYG test version 2.0: An even more rapid and simplified protocol for laboratory detection of the carbapenemase-producing Enterobacteriaceae, abstr P3066. Abstr 26th Eur Congr Clin Micrbiol Infect Dis, Amsterdam, the Netherlands.
18. Dortet L, Poirel L, Errera C, Nordmann P. 2014. CarbAcineto NP test for rapid detection of carbapenemase-producers in Acinetobacter spp. J Clin Microbiol 52:2359-2364. https://doi.org/10.1128/JCM.00594-14.
19. Clinical and Laboratory Standards Institute. 2015. Performance standards for antimicrobial susceptibility testing; 25th informational supplement. CLSI M100-S25. Clinical and Laboratory Standards Institute, Wayne, PA.
20. Bogaerts P, Rezende de Castro R, de Mendonca R, Huang TD, Denis O, Glupczynski Y. 2013. Validation of carbapenemase and extendedspectrum beta-lactamase multiplex endpoint PCR assays according to ISO 15189. J Antimicrob Chemother 68:1576-1582. https://doi.org/10.1093/jac/dkt065.
21. Nordmann P, Poirel L, Dortet L. 2012. Rapid detection of carbapenemaseproducing Enterobacteriaceae. Emerg Infect Dis 18:1503-1507. https://doi.org/10.3201/eid1809.120355.
22. Rosco Diagnostica. 2014. Rapid Carb screen kit version 98024, package insert revision DBV0040K. Rosco Diagnostica A/S, Taastrup, Denmark.
23. BioMérieux. 2015. Rapidec Carba NP, package insert version 20584. bioMérieux SA, Marcy-l'Etoile, France.
24. Bio-Rad. 2015. -eta-Carba test, package insert version 881159. Bio-Rad, Marnes-la-Coquette, France.