Qualitative and quantitative aspects of the inheritance of chemical phenotype in cannabis

Journal of Industrial Hemp

Volumn 8, Issue 2, 2003, Pages 51-72

  Mandolino, Giuseppe ^a   Bagatta, Manuela ^a   Carboni, Andrea ^a   Ranalli, Paolo ^a   De Meijer, Etienne ^b  

^a ISTITUTO NAZIONALE DELLA NUTRIZIONE   (Italy)

^b Porton Down Science Park   (United Kingdom)

Author keywords

Cannabis; Chemotype; Genetic analysis; Inheritance; RAPD markers

Indexed keywords

EID: 85011165173     PISSN: 15377881     EISSN: 1537789X     Source Type: Journal    
DOI: 10.1300/J237v08n02_04     Document Type: Article

References (41)

1. Becu D.M.S., H.D. Mastebroek and H.J.P. Marvin, 1998. Breeding for root knot nematode resistance in hemp. Proceedings of: Bast fibrous plants today and tomorrow, St. Petersburg, Sept. 28-30, p. 149.
2. Bócsa I., P. Mathé and L. Hangyel, 1997. Effect of nitrogen on tetrahydrocannabinol (THC) content in hemp (Cannabis sativa L.) leaves at different positions. J. Intl. Hemp Association 4: 80-81.
3. Crescini F., 1956. La fecondazione incestuosa processo mutageno in Cannabis sativa L. Caryologia 9: 82-92.
4. Faeti V., G. Mandolino and P. Ranalli, 1996. Genetic diversity of Cannabis sativa germplasm based on RAPD markers. Plant Breeding 115: 367-370.
5. Fellermeier M. and M.H. Zenk, 1998. Prenylation of olivetolate by a hemp transferase yields cannabigerolic acid, the precursor of tetrahydrocannabinol. FEBS letters 427: 283-285.
6. Fellermeier M., W. Eisenreich, A. Bacher and M.H. Zenk, 2001. Biosynthesis of cannabinoids. Incorporation experiments with 13C-labeled glucoses. Eur. J. Biochem. 268: 1596-1604.
7. Forapani S., A. Carboni, C. Paoletti, V.M.C. Moliterni, P. Ranalli and G. Mandolino, 2001. Comparison of hemp (Cannabis sativa L.) varieties using RAPD markers. Crop Sci. 41: 1682-1689.
8. Fournier G. and M.R. Paris, 1979. Le chanvre papetier (Cannabis sativa L.) cultivé en France: le point sur ses constituants. Plantes médicinales et phytothérapie 13:116-121.
9. Fournier G. & M. Paris, 1980. Détermination de chimiotypes à partir des cannabinoïdes chez le chanvre à fibres monoïque (Cannabis sativa L.) Possibilités de sélection. Physiologie Végétale 18: 349-356.
10. Fournier G., 1981. Les chimiotypes du chanvre (Cannabis sativa L.). Intérêt pour un programme de sélection. Agronomie 1: 679-688.
11. Fournier G., C. Richez-Dumanois, J. Duvezin, J.-P. Mathieu and M. Paris, 1987. Identification of a new chemotype in Cannabis sativa: cannabigerol-dominant plants, biogenetic and agronomic prospects. Planta Medica 53: 277-280.
12. Gaoni Y. and R. Mechoulam, 1964. The structure and synthesis of cannabigerol, a new hashish constituent. Proc. Chem. Soc., p. 82.
13. Gaoni Y. and R. Mechoulam, 1966. Cannabichromene, a new active principle in hashish. Chemical Communications 1: 20-21.
14. Grli L., 1968. A combined spectrophotometric differentiation of samples of Cannabis. Bull. Narcotics 20: 25.
15. Hammond C.T. and P.G. Mahlberg, 1977. Morphogenesis of capitate glandular hairs of Cannabis sativa (Cannabaceae). Amer. J. Bot. 64: 1023-1031.
16. Hillig K., 2002. Letter to the editor. J. of Industr. Hemp 7: 5-6.
17. Holley J.H., K.W. Hadley and C.E. Turner, 1975. Constituents of Cannabis sativa L. XI Cannabidiol and cannabichromene in samples of known geographical origin. J. of Pharm. Sci. 64: 892-894.
18. Lydon J., A.H. Teramura and C.B. Coffman, 1987. UV-B radiation effects on photosynthesis, growth and cannabinoid production of two Cannabis sativa chemotypes. Photochemistry and Photobiology 46: 201-206.
19. Mandolino G., A. Carboni, S. Forapani, V. Faeti and P. Ranalli, 1999. Identification of DNA markers linked to the male sex in dioecious hemp (Cannabis sativa L.). Theor. Appl. Genet. 98: 86-92.
20. Mandolino G. and P. Ranalli, 2002. The applications of molecular markers in genetics and breeding of hemp. J. of Industr. Hemp 7: 7-23.
21. Mechoulam R., 1970. Marijuana chemistry. Science 168: 1159-1166.
22. Meijer E.P.M. de, H.J. van der Kamp and F.A. van Eeuwijk, 1992. Characterisation of Cannabis accessions with regard to cannabinoid content in relation to other plant characters. Euphytica 62: 187-200.
23. Meijer E.P.M. de, M. Bagatta, A. Carboni, P. Crucitti, V.M.C. Moliterni, P. Ranalli and G. Mandolino, 2003. The inheritance of chemical phenotype in Cannabis sativa L. Genetics 163: 335-346.
24. Michelmore R.W., I. Paran and R.V. Kesseli, 1991. Identification of markers linked to disease-resistance genes by bulked segregant analysis: a rapid method to detect markers in specific genomic regions by using segregating populations. Proc. Natl. Acad. Sci. USA 88: 9828-9832.
25. Mohan Ram H.Y. and R. Sett, 1982. Induction of fertile male flowers in genetically female Cannabis sativa plants by silver nitrate and silver thiosulphate anionic complex. Theor. Appl. Genet. 62: 369-375.
26. Morimoto S., K. Komatsu, F. Taura and Y. Shoyama, 1997. Enzymological evidence for cannabichromenic acid biosynthesis. J. Nat. Prod. 60: 854-857.
27. Morimoto S., K. Komatsu, F. Taura and Y. Shoyama, 1998. Purification and characterization of cannabichromenic acid synthase from Cannabis sativa. Phytochemistry 49: 1525-1529.
28. Shoyama Y., M. Yagi and I. Nishioka, 1974. Biosynthesis of cannabinoid acids. Phytochemistry 14: 2189-2192.
29. Shoyama Y., H. Hirano and I. Nishioka, 1984. Biosynthesis of propyl cannabinoid acid and its biosynthetic relationship with pentyl and methyl cannabinoid acids. Phytochemistry 23: 1909-1912.
30. Small E. and H.D. Beckstead, 1973. Common cannabinoid phenotypes in 350 stocks of Cannabis. Lloydia 36: 144-165.
31. Small E., P.Y. Jui and L.P. Lefkovitch, 1976. A numerical taxonomy analysis of Cannabis with special reference to species delimitation. Systematic Botany 1: 67-84.
32. Sytnik V.P. and A.F. Stelmah, 1999. The character of inheritance of differences in cannabinoid content in hemp (Cannabis sativa L.). J. of the Intl. Hemp Ass. 6: 8-9.
33. Taura F., S. Morimoto and Y. Shoyama, 1995. First direct evidence for the mechanism of delta-1-tetrahydrocannabinolic acid biosynthesis. J. Am. Chem. Soc. 38: 9766-9767.
34. Taura F., S. Morimoto and Y. Shoyama, 1996. Purification and characterization of cannabidiolic-acid synthase from Cannabis sativa L. J. of Biol. Chem. 271: 17411-17416.
35. Taura T., H. Matsushita, S. Morimoto, PI Y. Masayama. Patents: JP 2000078979-A 1 and JP 2000078979-A 2, March 21, 2000.
36. Turner C.E., M.A. Elsohly, P.C. Cheng and G. Lewis, 1979. Constituents of Cannabis sativa L., XIV: intrinsic problems in classifying Cannabis based on a single cannabinoid analysis. J. of Natural Products 42: 317-319.
37. Williams J.G.K., A.R. Kubelik, K.J. Livak, J.A. Rafalski and S.V. Tingey. 1990. DNA polymorphism amplified by arbitrary primers are useful as genetic markers. Nucleic Acids Res. 18: 6531-6535.
38. Yoshikai K., T. Taura, S. Morimoto, PI Y. Masayama. Patents: JP 2001029082-A 1 and JP 2001029082-A 2, February 6, 2001.
39. Yotoriyama M., I. Ito, D. Takashima, Y. Shoyama and I. Nishioka, 1980. Breeding of Cannabis. Determination of cannabinoids by high-pressure liquid chromatography. Yakugaku Zasshi 100: 611-614.
40. Zeeuw R.A. de, Th.M. Malingre and F.W.H.M. Merkus, 1972a. Tetrahydrocannabinolic acid, an important component in the evaluation of Cannabis products. J. Pharm. Pharmacology 24: 1-6.
41. Zeeuw R.A. de, J. Wijsbek, D.D. Breimer, T.B. Vree, C.A. Van Ginneken and J.M. van Rossum, 1972b. Cannabinoids with a propyl side chain in Cannabis. Occurrence and chromatographic behaviour. Science 175: 778-779.