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Volumn 12, Issue 1, 2017, Pages

Blood trimethylamine-n-oxide originates from microbiota mediated breakdown of phosphatidylcholine and absorption from small intestine

Author keywords

[No Author keywords available]

Indexed keywords

CREATININE; PHOSPHATIDYLCHOLINE; RIFAXIMIN; TRIMETHYLAMINE; TRIMETHYLAMINE OXIDE; METHYLAMINE; MIXED FUNCTION OXIDASE; OXIDE; RIFAMYCIN; TRIMETHYLOXAMINE;

EID: 85010961081     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0170742     Document Type: Article
Times cited : (48)

References (17)
  • 1
    • 38649115342 scopus 로고    scopus 로고
    • Microbial influences in inflammatory bowel diseases
    • PMID: 18242222
    • Sartor RB. Microbial influences in inflammatory bowel diseases. Gastroenterology. 2008; 134(2):577-94. doi: 10.1053/j.gastro.2007.11.059 PMID: 18242222
    • (2008) Gastroenterology , vol.134 , Issue.2 , pp. 577-594
    • Sartor, R.B.1
  • 2
    • 19444375492 scopus 로고    scopus 로고
    • Mammalian flavin-containing monooxygenases: Structure/function, genetic polymorphisms and role in drug metabolism
    • PMID: 15922018
    • Krueger SK, Williams DE. Mammalian flavin-containing monooxygenases: structure/function, genetic polymorphisms and role in drug metabolism. Pharmacol Ther. 2005; 106(3):357-87. doi: 10.1016/j. pharmthera.2005.01.001 PMID: 15922018
    • (2005) Pharmacol Ther , vol.106 , Issue.3 , pp. 357-387
    • Krueger, S.K.1    Williams, D.E.2
  • 3
    • 0033959521 scopus 로고    scopus 로고
    • Population-specific polymorphisms of the human FMO3 gene: Significance for detoxication
    • PMID: 10640514
    • Cashman JR, Akerman BR, Forrest SM, Treacy EP. Population-specific polymorphisms of the human FMO3 gene: significance for detoxication. Drug Metab Dispos. 2000; 28(2):169-73. PMID: 10640514
    • (2000) Drug Metab Dispos , vol.28 , Issue.2 , pp. 169-173
    • Cashman, J.R.1    Akerman, B.R.2    Forrest, S.M.3    Treacy, E.P.4
  • 4
    • 84877858841 scopus 로고    scopus 로고
    • Phospholipid catabolism by gut microbiota and the risk of cardiovascular disease
    • PMID: 23518648
    • Sitaraman R. Phospholipid catabolism by gut microbiota and the risk of cardiovascular disease. J Med Microbiol. 2013; 62(Pt 6):948-50. doi: 10.1099/jmm.0.053587-0 PMID: 23518648
    • (2013) J Med Microbiol , vol.62 , pp. 948-950
    • Sitaraman, R.1
  • 5
    • 84910619978 scopus 로고    scopus 로고
    • Far from the eyes, close to the heart: Dysbiosis of gut microbiota and cardiovascular consequences
    • PMID: 25303894
    • Serino M, Blasco-Baque V, Nicolas S, Burcelin R. Far from the eyes, close to the heart: dysbiosis of gut microbiota and cardiovascular consequences. Curr Cardiol Rep. 2014; 16(11):540. doi: 10.1007/ s11886-014-0540-1 PMID: 25303894
    • (2014) Curr Cardiol Rep , vol.16 , Issue.11 , pp. 540
    • Serino, M.1    Blasco-Baque, V.2    Nicolas, S.3    Burcelin, R.4
  • 6
    • 33645664025 scopus 로고    scopus 로고
    • Diagnosis and management of trimethylaminuria (FMO3 deficiency) in children
    • PMID: 16601883
    • Chalmers RA, Bain MD, Michelakakis H, Zschocke J, Iles RA. Diagnosis and management of trimethylaminuria (FMO3 deficiency) in children. J Inherit Metab Dis. 2006; 29(1):162-72. doi: 10.1007/s10545-006-0158-6 PMID: 16601883
    • (2006) J Inherit Metab Dis , vol.29 , Issue.1 , pp. 162-172
    • Chalmers, R.A.1    Bain, M.D.2    Michelakakis, H.3    Zschocke, J.4    Iles, R.A.5
  • 7
    • 79953733693 scopus 로고    scopus 로고
    • Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease
    • PMID: 21475195
    • Wang Z, Klipfell E, Bennett BJ, Koeth R, Levison BS, Dugar B, et al. Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease. Nature. 2011; 472(7341):57-63. doi: 10.1038/ nature09922 PMID: 21475195
    • (2011) Nature , vol.472 , Issue.7341 , pp. 57-63
    • Wang, Z.1    Klipfell, E.2    Bennett, B.J.3    Koeth, R.4    Levison, B.S.5    Dugar, B.6
  • 8
    • 84876563088 scopus 로고    scopus 로고
    • Intestinal microbial metabolism of phosphatidylcholine and cardiovascular risk
    • PMID: 23614584
    • Tang WH, Wang Z, Levison BS, Koeth RA, Britt EB, Fu X, et al. Intestinal microbial metabolism of phosphatidylcholine and cardiovascular risk. N Engl J Med. 2013; 368(17):1575-84. doi: 10.1056/ NEJMoa1109400 PMID: 23614584
    • (2013) N Engl J Med , vol.368 , Issue.17 , pp. 1575-1584
    • Tang, W.H.1    Wang, Z.2    Levison, B.S.3    Koeth, R.A.4    Britt, E.B.5    Fu, X.6
  • 9
    • 9644265328 scopus 로고    scopus 로고
    • Choline- and betaine-defined diets for use in clinical research and for the management of trimethylaminuria
    • PMID: 15565078
    • Busby MG, Fischer L, da Costa KA, Thompson D, Mar MH, Zeisel SH. Choline- and betaine-defined diets for use in clinical research and for the management of trimethylaminuria. J Am Diet Assoc. 2004; 104(12):1836-45. doi: 10.1016/j.jada.2004.09.027 PMID: 15565078
    • (2004) J Am Diet Assoc , vol.104 , Issue.12 , pp. 1836-1845
    • Busby, M.G.1    Fischer, L.2    Da Costa, K.A.3    Thompson, D.4    Mar, M.H.5    Zeisel, S.H.6
  • 10
    • 77950246404 scopus 로고    scopus 로고
    • Rifaximin treatment in hepatic encephalopathy
    • PMID: 20335583
    • Bass NM, Mullen KD, Sanyal A, Poordad F, Neff G, Leevy CB, et al. Rifaximin treatment in hepatic encephalopathy. N Engl J Med. 2010; 362(12):1071-81. doi: 10.1056/NEJMoa0907893 PMID: 20335583
    • (2010) N Engl J Med , vol.362 , Issue.12 , pp. 1071-1081
    • Bass, N.M.1    Mullen, K.D.2    Sanyal, A.3    Poordad, F.4    Neff, G.5    Leevy, C.B.6
  • 11
    • 21044457089 scopus 로고    scopus 로고
    • Retarded release phosphatidylcholine benefits patients with chronic active ulcerative colitis
    • PMID: 15951544
    • Stremmel W, Merle U, Zahn A, Autschbach F, Hinz U, Ehehalt R. Retarded release phosphatidylcholine benefits patients with chronic active ulcerative colitis. Gut. 2005; 54(7):966-71. doi: 10.1136/gut.2004. 052316 PMID: 15951544
    • (2005) Gut , vol.54 , Issue.7 , pp. 966-971
    • Stremmel, W.1    Merle, U.2    Zahn, A.3    Autschbach, F.4    Hinz, U.5    Ehehalt, R.6
  • 12
    • 3142764042 scopus 로고    scopus 로고
    • Time- and pH-dependent colon-specific drug delivery for orally administered diclofenac sodium and 5-aminosalicylic acid
    • PMID: 15188503
    • Cheng G, An F, Zou MJ, Sun J, Hao XH, He YX. Time- and pH-dependent colon-specific drug delivery for orally administered diclofenac sodium and 5-aminosalicylic acid. World J Gastroenterol. 2004; 10 (12):1769-74. doi: 10.3748/wjg.v10.i12.1769 PMID: 15188503
    • (2004) World J Gastroenterol , vol.10 , Issue.12 , pp. 1769-1774
    • Cheng, G.1    An, F.2    Zou, M.J.3    Sun, J.4    Hao, X.H.5    He, Y.X.6
  • 13
    • 42049090570 scopus 로고    scopus 로고
    • A flow injection electrospray ionization tandem mass spectrometric method for the simultaneous measurement of trimethylamine and trimethylamine N-oxide in urine
    • PMID: 17975851
    • Johnson DW. A flow injection electrospray ionization tandem mass spectrometric method for the simultaneous measurement of trimethylamine and trimethylamine N-oxide in urine. J Mass Spectrom. 2008; 43(4):495-9. doi: 10.1002/jms.1339 PMID: 17975851
    • (2008) J Mass Spectrom , vol.43 , Issue.4 , pp. 495-499
    • Johnson, D.W.1
  • 14
    • 1642357692 scopus 로고    scopus 로고
    • Solid-phase microextraction: A powerful sample preparation tool prior to mass spectrometric analysis
    • PMID: 15039931
    • Vas G, Vekey K. Solid-phase microextraction: a powerful sample preparation tool prior to mass spectrometric analysis. J Mass Spectrom. 2004; 39(3):233-54. doi: 10.1002/jms.606 PMID: 15039931
    • (2004) J Mass Spectrom , vol.39 , Issue.3 , pp. 233-254
    • Vas, G.1    Vekey, K.2
  • 15
    • 0032977817 scopus 로고    scopus 로고
    • Quantitative determination of trimethylamine in urine by solid-phase microextraction and gas chromatography-mass spectrometry
    • PMID: 10080656
    • Mills GA, Walker V, Mughal H. Quantitative determination of trimethylamine in urine by solid-phase microextraction and gas chromatography-mass spectrometry. J Chromatogr B Biomed Sci Appl. 1999; 723(1-2):281-5. PMID: 10080656
    • (1999) J Chromatogr B Biomed Sci Appl , vol.723 , Issue.1-2 , pp. 281-285
    • Mills, G.A.1    Walker, V.2    Mughal, H.3
  • 16
    • 77956971129 scopus 로고    scopus 로고
    • A language and environment for statistical computing
    • Vienna / Austria2016
    • Team C. A language and environment for statistical computing. Foundation for Statistical Computing. Vienna / Austria2016.
    • Foundation for Statistical Computing
  • 17
    • 84903897973 scopus 로고    scopus 로고
    • First multicenter study of modified release phosphatidylcholine LT-02 in ulcerative colitis: A randomized, placebo-controlled trial in mesalazine-refractory courses
    • PMID: 24796768
    • Karner M, Kocjan A, Stein J, Schreiber S, von Boyen G, Uebel P, et al. First multicenter study of modified release phosphatidylcholine "LT-02" in ulcerative colitis: a randomized, placebo-controlled trial in mesalazine-refractory courses. Am J Gastroenterol. 2014; 109(7):1041-51. doi: 10.1038/ajg.2014.104 PMID: 24796768
    • (2014) Am J Gastroenterol , vol.109 , Issue.7 , pp. 1041-1051
    • Karner, M.1    Kocjan, A.2    Stein, J.3    Schreiber, S.4    Von Boyen, G.5    Uebel, P.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.