Is mirtazapine an effective treatment for nausea and vomiting of pregnancy?: A case series

Journal of Clinical Psychopharmacology

Volumn 37, Issue 2, 2017, Pages 260-261

  Omay, Oguz ^a   Einarson, Adrienne ^b  

^a La Teppe Medical Center   (France)

^b NONE   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CHLORPROMAZINE; CLORAZEPATE; DOXYLAMINE; MIRTAZAPINE; ONDANSETRON; ANTIDEPRESSANT AGENT;

ADULT; ANXIETY; CASE STUDY; CLINICAL ARTICLE; DEPRESSION; DRUG DOSE INCREASE; DRUG DOSE TITRATION; DRUG MEGADOSE; DRUG TREATMENT FAILURE; FEMALE; HUMAN; LETTER; NAUSEA AND VOMITING; PANIC; PREGNANCY DISORDER; PRIORITY JOURNAL; SPONTANEOUS ABORTION; SUICIDAL IDEATION; CASE REPORT; NAUSEA; PREGNANCY; PREGNANCY COMPLICATION; VOMITING;

ADULT; ANTIDEPRESSIVE AGENTS; FEMALE; HUMANS; MIRTAZAPINE; NAUSEA; PREGNANCY; PREGNANCY COMPLICATIONS; VOMITING;

EID: 85010910649     PISSN: 02710749     EISSN: 1533712X     Source Type: Journal    
DOI: 10.1097/JCP.0000000000000656     Document Type: Letter

References (14)

1. Gadsby R, Barnie-Adshead AM, Jagger C. A prospective study of nausea and vomiting during pregnancy. Br J Gen Pract. 1993;43: 245-248.
2. O'Brien B, Zhou Q. Variables related to nausea and vomiting during pregnancy. Birth. 1995;22: 93-100.
3. Marcus SM, Flynn HA, Blow FC, et al. Depressive symptoms among pregnant women screened in obstetric settings. J Women Health. 2003;12:373-380.
4. Anttila SA, Leinonen EV. A review of the pharmacological and clinical profile of mirtazapine. CNS Drug Rev. 2001;7: 249-264.
5. Chang FL, Ho ST, Sheen MJ. Efficacy of mirtazapine in preventing intrathecal morphine-induced nausea and vomiting after orthopaedic surgery. Anaesthesia. 2010;65: 1206-1211.
6. Smit M, Dolman KM, Honig A. Mirtazapine in pregnancy and lactation - a systematic review. Eur Neuropsychopharmacol. 2016;26: 126-135.
7. Saks BR. Mirtazapine: treatment of depression, anxiety and hyperemesis gravidarum in the pregnant patient. A report of 7 cases. Arch Womens Ment Health. 2001;3: 165-170.
8. Guclu S, Gol M, Dogan E, et al. Mirtazapine use in resistant hyperemesis gravidarum: report of three cases and review of the literature. Arch Gynecol Obstet. 2005;272: 298-300.
9. Uguz F. Low-dose mirtazapine added to selective serotonin reuptake inhibitors in pregnant women with major depression or panic disorder including symptoms of severe nausea, insomnia and decreased appetite: three cases. J Matern Fetal Neonatal Med. 2013;26: 1066-1068.
10. Uguz F. Low-dose mirtazapine in treatment of major depression developed following severe nausea and vomiting during pregnancy: two cases. Gen Hosp Psychiatry. 2014;36:125. e5-6.
11. Schwarzer V, Heep A, Gembruch U, et al. Treatment resistant hyperemesis gravidarum in a patient with type 1 diabetes mellitus: neonatal withdrawal symptoms after successful antiemetic therapy with mirtazapine. Arch Gynecol Obstet. 2008;277:67-69.
12. Rohde A, Dembinski J, Dorn C. Mirtazapine (Remergil) for treatment resistant hyperemesis gravidarum: rescue of a twin pregnancy. Arch Gynecol Obstet. 2003;268: 219-221. 23.
13. Lieb M, Palm U, Jacoby D, et al. Mirtazapine and hyperemesis gravidarum [in German. Nervenarzt. 2012;83:374-376.
14. Stroman D, Dossett E. Mirtazapine, pregnancy and hyperemesis gravidarum. In: Poster presented at the American Psychiatric Association's 167th annual meeting. NewYork, NY: May 2014.