Single-Dose Intracardiac Injection of Pro-Regenerative MicroRNAs Improves Cardiac Function after Myocardial Infarction

Circulation Research

Volumn 120, Issue 8, 2017, Pages 1298-1304

  Lesizza, Pierluigi ^a,b   Prosdocimo, Giulia ^a   Martinelli, Valentina ^a   Sinagra, Gianfranco ^a,b   Zacchigna, Serena ^b   Giacca, Mauro ^a,b  

^a INTERNATIONAL CENTRE FOR GENETIC ENGINEERING AND BIOTECHNOLOGY   (Italy)

^b UNIVERSITY OF TRIESTE   (Italy)

Author keywords

microRNA; myocardial infarction; regeneration; therapy; transfection

Indexed keywords

CARDIOVASCULAR AGENT; LIPOFECTAMINE; MICRORNA; MICRORNA 199A 3P; MICRORNA 590 3P; PROTEIN HOMER 1; UNCLASSIFIED DRUG; VIRUS VECTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CAENORHABDITIS ELEGANS; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; DOWN REGULATION; DRUG EFFICACY; ECHOCARDIOGRAPHY; FEMALE; FLUORESCENCE MICROSCOPY; FOLLOW UP; GENE EXPRESSION; GENE TRANSFER; HEART FUNCTION; HEART INFARCTION; HEART LEFT VENTRICLE EJECTION FRACTION; IN VIVO STUDY; LEFT ANTERIOR DESCENDING CORONARY ARTERY; MOUSE; NONHUMAN; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SINGLE DRUG DOSE; ANIMAL; CARDIAC MUSCLE CELL; CELL CULTURE; CONVALESCENCE; DISEASE MODEL; GENE EXPRESSION REGULATION; GENE THERAPY; GENETIC TRANSFECTION; GENETICS; HEART LEFT VENTRICLE FUNCTION; INJECTION; METABOLISM; MYOCARDIAL INFARCTION; PATHOLOGY; PATHOPHYSIOLOGY; PROCEDURES; REGENERATION; RNA INTERFERENCE; TIME FACTOR;

ANIMALS; APOPTOSIS; CELL PROLIFERATION; CELLS, CULTURED; DISEASE MODELS, ANIMAL; FEMALE; GENE EXPRESSION REGULATION; GENETIC THERAPY; INJECTIONS; MICRORNAS; MYOCARDIAL INFARCTION; MYOCYTES, CARDIAC; RECOVERY OF FUNCTION; REGENERATION; RNA INTERFERENCE; TIME FACTORS; TRANSFECTION; VENTRICULAR FUNCTION, LEFT;

EID: 85010901146     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.116.309589     Document Type: Article

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