-
1
-
-
0028779842
-
The pathogenesis of insulin-dependent diabetes mellitus
-
[1] Atkinson, M.A., Maclaren, N.K., The pathogenesis of insulin-dependent diabetes mellitus. N. Engl. J. Med. 331 (1994), 1428–1436.
-
(1994)
N. Engl. J. Med.
, vol.331
, pp. 1428-1436
-
-
Atkinson, M.A.1
Maclaren, N.K.2
-
2
-
-
44849112223
-
T cells in the pathogenesis of Type 1 diabetes
-
[2] Mallone, R., van Endert, P., T cells in the pathogenesis of Type 1 diabetes. Curr. Diab. Rep. 8 (2008), 101–106.
-
(2008)
Curr. Diab. Rep.
, vol.8
, pp. 101-106
-
-
Mallone, R.1
van Endert, P.2
-
3
-
-
57249096985
-
Adequate doses of autoantigen administered using the appropriate route may create tolerance and stop autoimmunity
-
[3] Ludvigsson, J., Adequate doses of autoantigen administered using the appropriate route may create tolerance and stop autoimmunity. Diabetologia 52 (2009), 175–176.
-
(2009)
Diabetologia
, vol.52
, pp. 175-176
-
-
Ludvigsson, J.1
-
4
-
-
0025039679
-
Identification of the 64 K autoantigen in insulin-dependent diabetes as the GABA-synthesizing enzyme glutamic acid decarboxylase
-
[4] Baekkeskov, S., Aanstoot, H.J., Christgau, S., Reetz, A., Solimena, M., Cascalho, M., Folli, F., Richter-Olesen, H., De Camilli, P., Identification of the 64 K autoantigen in insulin-dependent diabetes as the GABA-synthesizing enzyme glutamic acid decarboxylase. Nature 347 (1990), 151–156.
-
(1990)
Nature
, vol.347
, pp. 151-156
-
-
Baekkeskov, S.1
Aanstoot, H.J.2
Christgau, S.3
Reetz, A.4
Solimena, M.5
Cascalho, M.6
Folli, F.7
Richter-Olesen, H.8
De Camilli, P.9
-
5
-
-
55249110198
-
GAD treatment and insulin secretion in recent-onset Type 1 diabetes
-
[5] Ludvigsson, J., Faresjo, M., Hjorth, M., Axelsson, S., Cheramy, M., Pihl, M., Vaarala, O., Forsander, G., Ivarsson, S., Johansson, C., Lindh, A., Nilsson, N.O., Aman, J., Ortqvist, E., Zerhouni, P., Casas, R., GAD treatment and insulin secretion in recent-onset Type 1 diabetes. N. Engl. J. Med. 359 (2008), 1909–1920.
-
(2008)
N. Engl. J. Med.
, vol.359
, pp. 1909-1920
-
-
Ludvigsson, J.1
Faresjo, M.2
Hjorth, M.3
Axelsson, S.4
Cheramy, M.5
Pihl, M.6
Vaarala, O.7
Forsander, G.8
Ivarsson, S.9
Johansson, C.10
Lindh, A.11
Nilsson, N.O.12
Aman, J.13
Ortqvist, E.14
Zerhouni, P.15
Casas, R.16
-
6
-
-
21344461521
-
65 immunomodulation in adult-onset autoimmune diabetes
-
65 immunomodulation in adult-onset autoimmune diabetes. J. Diabetes Complicat. 19 (2005), 238–246.
-
(2005)
J. Diabetes Complicat.
, vol.19
, pp. 238-246
-
-
Agardh, C.D.1
Cilio, C.M.2
Lethagen, A.3
Lynch, K.4
Leslie, R.D.5
Palmer, M.6
Harris, R.A.7
Robertson, J.A.8
Lernmark, A.9
-
7
-
-
79960743608
-
Antigen-based therapy with glutamic acid decarboxylase (GAD) vaccine in patients with recent-onset Type 1 diabetes: a randomised double-blind trial
-
[7] Wherrett, D.K., Bundy, B., Becker, D.J., DiMeglio, L.A., Gitelman, S.E., Goland, R., Gottlieb, P.A., Greenbaum, C.J., Herold, K.C., Marks, J.B., Monzavi, R., Moran, A., Orban, T., Palmer, J.P., Raskin, P., Rodriguez, H., Schatz, D., Wilson, D.M., Krischer, J.P., Skyler, J.S., Antigen-based therapy with glutamic acid decarboxylase (GAD) vaccine in patients with recent-onset Type 1 diabetes: a randomised double-blind trial. Lancet 378 (2011), 319–327.
-
(2011)
Lancet
, vol.378
, pp. 319-327
-
-
Wherrett, D.K.1
Bundy, B.2
Becker, D.J.3
DiMeglio, L.A.4
Gitelman, S.E.5
Goland, R.6
Gottlieb, P.A.7
Greenbaum, C.J.8
Herold, K.C.9
Marks, J.B.10
Monzavi, R.11
Moran, A.12
Orban, T.13
Palmer, J.P.14
Raskin, P.15
Rodriguez, H.16
Schatz, D.17
Wilson, D.M.18
Krischer, J.P.19
Skyler, J.S.20
more..
-
8
-
-
79953756466
-
Extended evaluation of the safety and efficacy of GAD treatment of children and adolescents with recent-onset Type 1 diabetes: a randomised controlled trial
-
[8] Ludvigsson, J., Hjorth, M., Cheramy, M., Axelsson, S., Pihl, M., Forsander, G., Nilsson, N.O., Samuelsson, B.O., Wood, T., Aman, J., Ortqvist, E., Casas, R., Extended evaluation of the safety and efficacy of GAD treatment of children and adolescents with recent-onset Type 1 diabetes: a randomised controlled trial. Diabetologia 54 (2011), 634–640.
-
(2011)
Diabetologia
, vol.54
, pp. 634-640
-
-
Ludvigsson, J.1
Hjorth, M.2
Cheramy, M.3
Axelsson, S.4
Pihl, M.5
Forsander, G.6
Nilsson, N.O.7
Samuelsson, B.O.8
Wood, T.9
Aman, J.10
Ortqvist, E.11
Casas, R.12
-
9
-
-
78651376427
-
Early induction of GAD(65)-reactive Th2 response in type 1 diabetic children treated with alum-formulated GAD(65)
-
[9] Axelsson, S., Hjorth, M., Akerman, L., Ludvigsson, J., Casas, R., Early induction of GAD(65)-reactive Th2 response in type 1 diabetic children treated with alum-formulated GAD(65). Diabetes Metab. Res. Rev. 26 (2010), 559–568.
-
(2010)
Diabetes Metab. Res. Rev.
, vol.26
, pp. 559-568
-
-
Axelsson, S.1
Hjorth, M.2
Akerman, L.3
Ludvigsson, J.4
Casas, R.5
-
10
-
-
83155164619
-
Long-lasting immune responses 4 years after GAD-alum treatment in children with Type 1 diabetes
-
[10] Axelsson, S., Cheramy, M., Hjorth, M., Pihl, M., Akerman, L., Martinuzzi, E., Mallone, R., Ludvigsson, J., Casas, R., Long-lasting immune responses 4 years after GAD-alum treatment in children with Type 1 diabetes. PLoS One, 6, 2011, e29008.
-
(2011)
PLoS One
, vol.6
-
-
Axelsson, S.1
Cheramy, M.2
Hjorth, M.3
Pihl, M.4
Akerman, L.5
Martinuzzi, E.6
Mallone, R.7
Ludvigsson, J.8
Casas, R.9
-
12
-
-
84876730093
-
Regulatory T cell phenotype and function 4 years after GAD-alum treatment in children with Type 1 diabetes
-
[12] Pihl, M., Akerman, L., Axelsson, S., Cheramy, M., Hjorth, M., Mallone, R., Ludvigsson, J., Casas, R., Regulatory T cell phenotype and function 4 years after GAD-alum treatment in children with Type 1 diabetes. Clin. Exp. Immunol. 172 (2013), 394–402.
-
(2013)
Clin. Exp. Immunol.
, vol.172
, pp. 394-402
-
-
Pihl, M.1
Akerman, L.2
Axelsson, S.3
Cheramy, M.4
Hjorth, M.5
Mallone, R.6
Ludvigsson, J.7
Casas, R.8
-
14
-
-
84856564903
-
65 antigen therapy in recently diagnosed Type 1 diabetes mellitus
-
65 antigen therapy in recently diagnosed Type 1 diabetes mellitus. N. Engl. J. Med. 366 (2012), 433–442.
-
(2012)
N. Engl. J. Med.
, vol.366
, pp. 433-442
-
-
Ludvigsson, J.1
Krisky, D.2
Casas, R.3
Battelino, T.4
Castano, L.5
Greening, J.6
Kordonouri, O.7
Otonkoski, T.8
Pozzilli, P.9
Robert, J.J.10
Veeze, H.J.11
Palmer, J.12
-
15
-
-
84903721001
-
G.A.D.s.g.i.S. clinical, GAD-treatment of children and adolescents with recent-onset Type 1 diabetes preserves residual insulin secretion after 30 months
-
[15] Ludvigsson, J., Cheramy, M., Axelsson, S., Pihl, M., Akerman, L., Casas, R., G.A.D.s.g.i.S. clinical, GAD-treatment of children and adolescents with recent-onset Type 1 diabetes preserves residual insulin secretion after 30 months. Diabetes Metab. Res. Rev. 30 (2014), 405–414.
-
(2014)
Diabetes Metab. Res. Rev.
, vol.30
, pp. 405-414
-
-
Ludvigsson, J.1
Cheramy, M.2
Axelsson, S.3
Pihl, M.4
Akerman, L.5
Casas, R.6
-
16
-
-
84900462616
-
Restoring the balance: immunotherapeutic combinations for autoimmune disease
-
[16] Smilek, D.E., Ehlers, M.R., Nepom, G.T., Restoring the balance: immunotherapeutic combinations for autoimmune disease. Dis. Model. Mech. 7 (2014), 503–513.
-
(2014)
Dis. Model. Mech.
, vol.7
, pp. 503-513
-
-
Smilek, D.E.1
Ehlers, M.R.2
Nepom, G.T.3
-
17
-
-
77950649733
-
Developing combination immunotherapies for Type 1 diabetes: recommendations from the ITN-JDRF Type 1 diabetes Combination Therapy Assessment Group
-
[17] Matthews, J.B., Staeva, T.P., Bernstein, P.L., Peakman, M., von Herrath, M., I.-J. Group, Developing combination immunotherapies for Type 1 diabetes: recommendations from the ITN-JDRF Type 1 diabetes Combination Therapy Assessment Group. Clin. Exp. Immunol. 160 (2010), 176–184.
-
(2010)
Clin. Exp. Immunol.
, vol.160
, pp. 176-184
-
-
Matthews, J.B.1
Staeva, T.P.2
Bernstein, P.L.3
Peakman, M.4
von Herrath, M.5
I.-J. Group6
-
18
-
-
84856402593
-
DIAPREV-IT study of diabetes therapy Diamyd(R) receives further funding and will continue despite disappointing Phase III trial results
-
[18] DIAPREV-IT study of diabetes therapy Diamyd(R) receives further funding and will continue despite disappointing Phase III trial results. Immunotherapy, 3, 2011, 923–924.
-
(2011)
Immunotherapy
, vol.3
, pp. 923-924
-
-
-
19
-
-
79551714647
-
65 protect insulin-production in the pancreatic islet beta cells?
-
65 protect insulin-production in the pancreatic islet beta cells?. Hum. Vaccin. 7 (2011), 45–49.
-
(2011)
Hum. Vaccin.
, vol.7
, pp. 45-49
-
-
Larsson, H.E.1
Lernmark, A.2
-
20
-
-
84891868411
-
Cellular and humoral immune responses in type 1 diabetic patients participating in a phase III GAD-alum intervention trial
-
[20] Axelsson, S., Chéramy, M., Akerman, L., Pihl, M., Ludvigsson, J., Casas, R., Cellular and humoral immune responses in type 1 diabetic patients participating in a phase III GAD-alum intervention trial. Diabetes Care 36 (2013), 3418–3424.
-
(2013)
Diabetes Care
, vol.36
, pp. 3418-3424
-
-
Axelsson, S.1
Chéramy, M.2
Akerman, L.3
Pihl, M.4
Ludvigsson, J.5
Casas, R.6
-
21
-
-
33751336357
-
A real-time PCR approach for rapid high resolution subtyping of HLA-DRB1*04
-
[21] Gersuk, V.H., Nepom, G.T., A real-time PCR approach for rapid high resolution subtyping of HLA-DRB1*04. J. Immunol. Methods 317 (2006), 64–70.
-
(2006)
J. Immunol. Methods
, vol.317
, pp. 64-70
-
-
Gersuk, V.H.1
Nepom, G.T.2
-
22
-
-
62749201002
-
Expansion of human regulatory T-cells from patients with Type 1 diabetes
-
[22] Putnam, A.L., Brusko, T.M., Lee, M.R., Liu, W., Szot, G.L., Ghosh, T., Atkinson, M.A., Bluestone, J.A., Expansion of human regulatory T-cells from patients with Type 1 diabetes. Diabetes 58 (2009), 652–662.
-
(2009)
Diabetes
, vol.58
, pp. 652-662
-
-
Putnam, A.L.1
Brusko, T.M.2
Lee, M.R.3
Liu, W.4
Szot, G.L.5
Ghosh, T.6
Atkinson, M.A.7
Bluestone, J.A.8
-
23
-
-
84891868411
-
Cellular and humoral immune responses in Type 1 Diabetic patients participating in a phase III GAD-alum intervention trial
-
[23] Axelsson, S., Cheramy, M., Akerman, L., Pihl, M., Ludvigsson, J., Casas, R., Cellular and humoral immune responses in Type 1 Diabetic patients participating in a phase III GAD-alum intervention trial. Diabetes Care 36 (2013), 3418–3424.
-
(2013)
Diabetes Care
, vol.36
, pp. 3418-3424
-
-
Axelsson, S.1
Cheramy, M.2
Akerman, L.3
Pihl, M.4
Ludvigsson, J.5
Casas, R.6
-
24
-
-
77955890953
-
Interleukin-2 receptor signaling: at the interface between tolerance and immunity
-
[24] Malek, T.R., Castro, I., Interleukin-2 receptor signaling: at the interface between tolerance and immunity. Immunity 33 (2010), 153–165.
-
(2010)
Immunity
, vol.33
, pp. 153-165
-
-
Malek, T.R.1
Castro, I.2
-
25
-
-
55449111318
-
Increased resistance to CD4 + CD25hi regulatory T cell-mediated suppression in patients with Type 1 diabetes
-
[25] Lawson, J.M., Tremble, J., Dayan, C., Beyan, H., Leslie, R.D.G., Peakman, M., Tree, T.I.M., Increased resistance to CD4 + CD25hi regulatory T cell-mediated suppression in patients with Type 1 diabetes. Clin. Exp. Immunol. 154 (2008), 353–359.
-
(2008)
Clin. Exp. Immunol.
, vol.154
, pp. 353-359
-
-
Lawson, J.M.1
Tremble, J.2
Dayan, C.3
Beyan, H.4
Leslie, R.D.G.5
Peakman, M.6
Tree, T.I.M.7
-
26
-
-
58149188480
-
The effector T cells of diabetic subjects are resistant to regulation via CD4 + FOXP3 + regulatory T cells
-
[26] Schneider, A., Rieck, M., Sanda, S., Pihoker, C., Greenbaum, C., Buckner, J.H., The effector T cells of diabetic subjects are resistant to regulation via CD4 + FOXP3 + regulatory T cells. J. Immunol. 181 (2008), 7350–7355.
-
(2008)
J. Immunol.
, vol.181
, pp. 7350-7355
-
-
Schneider, A.1
Rieck, M.2
Sanda, S.3
Pihoker, C.4
Greenbaum, C.5
Buckner, J.H.6
-
27
-
-
84954443667
-
Type 1 diabetes immunotherapy using polyclonal regulatory T cells
-
[27] Bluestone, J.A., Buckner, J.H., Fitch, M., Gitelman, S.E., Gupta, S., Hellerstein, M.K., Herold, K.C., Lares, A., Lee, M.R., Li, K., Liu, W., Long, A.S., Masiello, L.M., Nguyen, V., Putnam, A.L., Rieck, M., Sayre, P.H., Tang, Q., Type 1 diabetes immunotherapy using polyclonal regulatory T cells. Sci. Transl. Med., 7, 2015.
-
(2015)
Sci. Transl. Med.
, vol.7
-
-
Bluestone, J.A.1
Buckner, J.H.2
Fitch, M.3
Gitelman, S.E.4
Gupta, S.5
Hellerstein, M.K.6
Herold, K.C.7
Lares, A.8
Lee, M.R.9
Li, K.10
Liu, W.11
Long, A.S.12
Masiello, L.M.13
Nguyen, V.14
Putnam, A.L.15
Rieck, M.16
Sayre, P.H.17
Tang, Q.18
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