Renal tubular resistance is the primary driver for loop diuretic resistance in acute heart failure

European Journal of Heart Failure

Volumn 19, Issue 8, 2017, Pages 1014-1022

  ter Maaten, Jozine M ^a,b   Rao, Veena S ^a,c   Hanberg, Jennifer S ^a   Perry Wilson, F ^a,d   Bellumkonda, Lavanya ^d   Assefa, Mahlet ^a   Sam Broughton, J ^a   D'Ambrosi, Julie ^c   Wilson Tang, W H ^e   Damman, Kevin ^b   Voors, Adriaan A ^b   Ellison, David H ^f   Testani, Jeffrey M ^a,d  

^a YALE UNIVERSITY   (United States)

^b UNIVERSITY MEDICAL CENTER GRONINGEN   (Netherlands)

^c YALE NEW HAVEN HOSPITAL   (United States)

^d YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e LERNER RESEARCH INSTITUTE   (United States)

^f OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

Diuretic resistance; Diuretic response; Heart failure; Mechanisms

Indexed keywords

BUMETANIDE; FUROSEMIDE; LOOP DIURETIC AGENT; SODIUM; UREA; BIOLOGICAL MARKER;

ACUTE HEART FAILURE; ADULT; ARTICLE; BLADDER DYSFUNCTION; CHRONIC KIDNEY FAILURE; DRUG DELIVERY SYSTEM; DRUG RESISTANCE; DRUG RESPONSE; DRUG URINE LEVEL; ESTIMATED GLOMERULAR FILTRATION RATE; FEMALE; HEART FAILURE; HUMAN; INCONTINENCE; KIDNEY TUBULE DISORDER; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; PRIORITY JOURNAL; RENAL CLEARANCE; URINE SAMPLING; ACUTE DISEASE; DOSE RESPONSE; DRUG EFFECT; GLOMERULUS FILTRATION RATE; INTRAVENOUS DRUG ADMINISTRATION; KIDNEY; KIDNEY TUBULE; METABOLISM; PATHOPHYSIOLOGY; PHYSIOLOGY; URINE;

ACUTE DISEASE; ADMINISTRATION, INTRAVENOUS; BIOMARKERS; BUMETANIDE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG RESISTANCE; FEMALE; GLOMERULAR FILTRATION RATE; HEART FAILURE; HUMANS; KIDNEY; KIDNEY TUBULES; MALE; MIDDLE AGED; SODIUM; SODIUM POTASSIUM CHLORIDE SYMPORTER INHIBITORS;

EID: 85010470220     PISSN: 13889842     EISSN: 18790844     Source Type: Journal    
DOI: 10.1002/ejhf.757     Document Type: Article

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