Identification of 5-methoxy-2-(diformylmethylidene)-3,3-dimethylindole as an anti-influenza a virus agent

PLoS ONE

Volumn 12, Issue 1, 2017, Pages

  Tan, Ming Cheang ^a   Wong, Wan Ying ^a   Ng, Wei Lun ^a   Yeo, Kok Siong ^a   Begam, Taznim ^a   Mohidin, Mohd ^a   Lim, Yat Yuen ^a   Lafta, Fadhil ^b   Ali, Hapipah Mohd ^b   Ea, Chee Kwee ^a,c  

^a UNIVERSITY OF MALAYA   (Malaysia)

^b UNIVERSITY OF MALAYA   (Malaysia)

^c UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

5 CHLORO 2 (DIFORMYLMETHYLIDENE) 3,3 DIMETHYLINDOLE; 5 METHOXY 2 (DIFORMYLMETHYLIDENE) 3,3 DIMETHYLINDOLE; 5 TRIFLUOROMETHOXY 2 (DIFORMYLMETHYLIDENE) 3,3 DIMETHYLINDOLE; 6 BROMO 2 (DIFORMYLMETHYLIDENE) 3,3 DIMETHYLINDOLE; ANTIVIRUS AGENT; INDOLE DERIVATIVE; INTERFERON; INTERFERON REGULATORY FACTOR 3; RETINOIC ACID INDUCIBLE PROTEIN I; STAT1 PROTEIN; UNCLASSIFIED DRUG; 5-METHOXY-2-(DIFORMYLMETHYLIDENE)-3,3-DIMETHYLINDOLE; MALONALDEHYDE;

ANTIVIRAL ACTIVITY; ARTICLE; CELL PROTECTION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG IDENTIFICATION; DRUG MECHANISM; DRUG SCREENING; DRUG STRUCTURE; EMBRYO; ENZYME ACTIVATION; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; INFECTION PREVENTION; INFLUENZA A; INFLUENZA A VIRUS; INTERFERON PRODUCTION; NONHUMAN; PROTEIN EXPRESSION; VIRUS CELL INTERACTION; VIRUS GENE; VIRUS INHIBITION; VIRUS REPLICATION; ANALOGS AND DERIVATIVES; ANIMAL; DRUG EFFECTS; METABOLISM; PHYSIOLOGY;

ANIMALS; ANTIVIRAL AGENTS; HUMANS; INDOLES; INFLUENZA A VIRUS; INTERFERON REGULATORY FACTOR-3; MALONDIALDEHYDE; STAT1 TRANSCRIPTION FACTOR; VIRUS REPLICATION;

EID: 85010426169     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0170352     Document Type: Article

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