메뉴 건너뛰기




Volumn 46, Issue 3, 1997, Pages 141-153

Cytoplasmic lipid bodies in eosinophils: Central roles in eicosanoid generation

Author keywords

aspirin; cyclooxygenase; eosinophils; leukotrienes; lipid bodies; lipoxygenase; platelet activating factor

Indexed keywords


EID: 85010134012     PISSN: 13238930     EISSN: 14401592     Source Type: Journal    
DOI: 10.2332/allergolint.46.141     Document Type: Review
Times cited : (4)

References (75)
  • 1
    • 0001826524 scopus 로고
    • 3H]-arachidonic acid incorporated by mast cells, macrophages and other cell types
    • In: Bailey JM (ed.), New York: Plenum Publishing Co.
    • 3H]-arachidonic acid incorporated by mast cells, macrophages and other cell types. In: Bailey JM (ed.). Prostaglandins, leukotrienes, and lipoxins. New York: Plenum Publishing Co., 1985; 221–39.
    • (1985) Prostaglandins, leukotrienes, and lipoxins
    • Galli, S.J.1    Dvorak, A.M.2    Peters, S.P.3
  • 2
    • 0019162068 scopus 로고
    • The cholesteryl ester cycle in macrophage foam cells. Continual hydrolysis and re-esterification of cytoplasmic cholesteryl esters
    • Brown, MS, Ho, YK, Goldstein, JL. The cholesteryl ester cycle in macrophage foam cells. Continual hydrolysis and re-esterification of cytoplasmic cholesteryl esters. J. Biol. Chem. 1980; 255: 9344–52.
    • (1980) J. Biol. Chem. , vol.255
    • Brown, M.S.1    Ho, Y.K.2    Goldstein, J.L.3
  • 3
    • 0021912903 scopus 로고
    • Arachidonic acid incorporation by cytoplasmic lipid bodies of human eosinophils
    • Weller, PF, Dvorak, AM. Arachidonic acid incorporation by cytoplasmic lipid bodies of human eosinophils. Blood 1985; 65: 1269–74.
    • (1985) Blood , vol.65
    • Weller, P.F.1    Dvorak, A.M.2
  • 5
    • 0015115697 scopus 로고
    • The presence of lipid droplets and the absence of stable sudanophilia in osmium-fixed human leukocytes
    • Coimbra, A, Lopes-Vaz, A. The presence of lipid droplets and the absence of stable sudanophilia in osmium-fixed human leukocytes. J. Histochem. Cytochem. 1971; 19: 551–7.
    • (1971) J. Histochem. Cytochem. , vol.19
    • Coimbra, A.1    Lopes-Vaz, A.2
  • 6
    • 0020446224 scopus 로고
    • Glycogen accumulation in polymorphonuclear leukocytes, and other intracellular alterations that occur during inflammation
    • Robinson, JM, Karnovsky, ML, Karnovsky, MJ. Glycogen accumulation in polymorphonuclear leukocytes, and other intracellular alterations that occur during inflammation. J. Cell Biol. 1982; 95: 933–42.
    • (1982) J. Cell Biol. , vol.95
    • Robinson, J.M.1    Karnovsky, M.L.2    Karnovsky, M.J.3
  • 7
    • 0028883446 scopus 로고
    • Migration of human inflammatory cells into the lung results in the remodeling of arachidonic acid into a triglyceride pool
    • Triggiani, M, Oriente, A, Seeds, MC, Bass, DA, Marone, G, Chilton, FH. Migration of human inflammatory cells into the lung results in the remodeling of arachidonic acid into a triglyceride pool. J. Exp. Med. 1995; 182: 1181–90.
    • (1995) J. Exp. Med. , vol.182
    • Triggiani, M.1    Oriente, A.2    Seeds, M.C.3    Bass, D.A.4    Marone, G.5    Chilton, F.H.6
  • 8
    • 0025729115 scopus 로고
    • Morphologic changes in the human amnion epithelium that accompany labor as seen with scanning and transmission electron microscopy
    • Sonek, J, Gabbe, SG, Lams, JD, Kniss, DA. Morphologic changes in the human amnion epithelium that accompany labor as seen with scanning and transmission electron microscopy. Am. J. Obstet. Gynecol. 1991; 164: 11 74–80.
    • (1991) Am. J. Obstet. Gynecol. , vol.164 , Issue.11 , pp. 74-80
    • Sonek, J.1    Gabbe, S.G.2    Lams, J.D.3    Kniss, D.A.4
  • 10
    • 0028366749 scopus 로고
    • Eicosanoids in leukocyte function
    • Serhan, CN. Eicosanoids in leukocyte function. Curr. Opin. Hematol. 1994; 1: 69–77.
    • (1994) Curr. Opin. Hematol. , vol.1 , pp. 69-77
    • Serhan, C.N.1
  • 12
    • 0027304229 scopus 로고
    • Arachidonic acid in cell signaling
    • Piomelli, D. Arachidonic acid in cell signaling. Curr. Opin. Cell Biol. 1993; 5: 274–80.
    • (1993) Curr. Opin. Cell Biol. , vol.5
    • Piomelli, D.1
  • 13
    • 0028566488 scopus 로고
    • The role of leukotrienes in inflammation
    • Henderson, WR Jr. The role of leukotrienes in inflammation. Ann. Intern. Med. 1994; 121: 684–97.
    • (1994) Ann. Intern. Med. , vol.121
    • Henderson, W.R.1
  • 14
  • 15
    • 0026702494 scopus 로고
    • Structure of the mitogen-inducible TIS10 gene and demonstration that the TIS10-encoded protein is a functional prostaglandin G/H synthase
    • Fletcher, BS, Kujubu, DA, Perrin, DM, Herschman, HR. Structure of the mitogen-inducible TIS10 gene and demonstration that the TIS10-encoded protein is a functional prostaglandin G/H synthase. J. Biol. Chem. 1992; 267: 4338–44.
    • (1992) J. Biol. Chem. , vol.267
    • Fletcher, B.S.1    Kujubu, D.A.2    Perrin, D.M.3    Herschman, H.R.4
  • 16
    • 0028360997 scopus 로고
    • Pharmacology of prostaglandin endoperoxide synthase isozymes-1 and -2
    • Smith, WL, Meade, EA, DeWitt, DL. Pharmacology of prostaglandin endoperoxide synthase isozymes-1 and -2. Ann. N.Y.Acad. Sci. 1994; 714: 136–42.
    • (1994) Ann. N.Y.Acad. Sci. , vol.714
    • Smith, W.L.1    Meade, E.A.2    DeWitt, D.L.3
  • 17
    • 0019961652 scopus 로고
    • How is the level of free arachidonic acid controlled in mammalian cells?
    • Irvine, RF. How is the level of free arachidonic acid controlled in mammalian cells? Biochem. J. 1982; 204: 3–16.
    • (1982) Biochem. J. , vol.204 , pp. 3-16
    • Irvine, R.F.1
  • 18
    • 0023025538 scopus 로고
    • Remodeling of arachidonate-containing phosphoglycerides within the human neutrophil
    • Chilton, FH, Murphy, RC. Remodeling of arachidonate-containing phosphoglycerides within the human neutrophil. J. Biol. Chem. 1986; 261: 7771–7.
    • (1986) J. Biol. Chem. , vol.261
    • Chilton, F.H.1    Murphy, R.C.2
  • 19
    • 0019419424 scopus 로고
    • Control of arachidonic acid accumulation in bone marrow-derived macrophages by acyltransferases
    • Kroner, EE, Peskar, BA, Fischer, H, Ferber, E. Control of arachidonic acid accumulation in bone marrow-derived macrophages by acyltransferases. J. Biol. Chem. 1981; 256: 3690–7.
    • (1981) J. Biol. Chem. , vol.256
    • Kroner, E.E.1    Peskar, B.A.2    Fischer, H.3    Ferber, E.4
  • 25
    • 0025220501 scopus 로고
    • 2with membrane in the macrophage cell line RAW 264.7
    • 2with membrane in the macrophage cell line RAW 264.7. J. Biol. Chem. 1990; 265: 5409–13.
    • (1990) J. Biol. Chem. , vol.265
    • Channon, J.Y.1    Leslie, C.C.2
  • 26
    • 0028969527 scopus 로고
    • Different intracellular locations for prostaglandin endoperoxide H synthase-1 and -2
    • Morita, I, Schindler, M, Regier, MK et al. Different intracellular locations for prostaglandin endoperoxide H synthase-1 and -2. J. Biol. Chem. 1995; 270: 10 902–8.
    • (1995) J. Biol. Chem. , vol.270 , Issue.10
    • Morita, I.1    Schindler, M.2    Regier, M.K.3
  • 28
    • 0028199075 scopus 로고
    • Ligand-induced prostaglandin synthesis requires expression of the TIS10/PGS-2 prostaglandin synthase gene in murine fibroblasts and macrophages
    • Reddy, ST, Herschman, HR. Ligand-induced prostaglandin synthesis requires expression of the TIS10/PGS-2 prostaglandin synthase gene in murine fibroblasts and macrophages. J. Biol. Chem. 1994; 269: 15 473–80.
    • (1994) J. Biol. Chem. , vol.269 , Issue.15
    • Reddy, S.T.1    Herschman, H.R.2
  • 29
    • 0027076645 scopus 로고
    • Selective expression of mitogen-inducible cyclooxygenase in macrophages stimulated with lipopolysaccharide
    • Lee, SH, Soyoola, E, Chanmugam, P et al. Selective expression of mitogen-inducible cyclooxygenase in macrophages stimulated with lipopolysaccharide. J. Biol. Chem. 1992; 267: 25 934–8.
    • (1992) J. Biol. Chem. , vol.267 , Issue.25
    • Lee, S.H.1    Soyoola, E.2    Chanmugam, P.3
  • 30
    • 0023803150 scopus 로고
    • Translocation of 5-lipoxygenase to the membrane in human leukocytes challenged with ionophore A23187
    • Rouzer, CA, Kargman, S. Translocation of 5-lipoxygenase to the membrane in human leukocytes challenged with ionophore A23187. J. Biol. Chem. 1988; 263: 10980–8.
    • (1988) J. Biol. Chem. , vol.263
    • Rouzer, C.A.1    Kargman, S.2
  • 31
    • 0023920874 scopus 로고
    • Arachidonate 15-lipoxygenase (ω-6 lipoxygenase) from human leukocytes. Purification and structural homology to other mammalian lipoxygenases
    • Sigal, E, Grunberger, D, Craik, CS, Caughey, GH, Nadel, JA. Arachidonate 15-lipoxygenase (ω-6 lipoxygenase) from human leukocytes. Purification and structural homology to other mammalian lipoxygenases. J. Biol. Chem. 1988; 263:5328–32.
    • (1988) J. Biol. Chem. , vol.263
    • Sigal, E.1    Grunberger, D.2    Craik, C.S.3    Caughey, G.H.4    Nadel, J.A.5
  • 33
    • 0025098441 scopus 로고
    • MK886, a potent and specific leukotriene biosynthesis inhibitor blocks and reverses the membrane association of 5-lipoxygenase in ionophore-challenged leukocytes
    • Rouzer, CA, Ford Hutchinson, AW, Morton, HE, Gillard, JW. MK886, a potent and specific leukotriene biosynthesis inhibitor blocks and reverses the membrane association of 5-lipoxygenase in ionophore-challenged leukocytes. J. Biol. Chem. 1990; 265: 1436–42.
    • (1990) J. Biol. Chem. , vol.265
    • Rouzer, C.A.1    Ford Hutchinson, A.W.2    Morton, H.E.3    Gillard, J.W.4
  • 34
    • 0027504207 scopus 로고
    • 5-Lipoxygenase and 5-lipoxygenase-activating protein are localized in the nuclear envelope of activated human leukocytes
    • Woods, JW, Evans, JF, Ethier, D et al. 5-Lipoxygenase and 5-lipoxygenase-activating protein are localized in the nuclear envelope of activated human leukocytes. J. Exp. Med. 1993; 178: 1935–46.
    • (1993) J. Exp. Med. , vol.178
    • Woods, J.W.1    Evans, J.F.2    Ethier, D.3
  • 35
    • 0027964479 scopus 로고
    • Localization of 5-lipoxygenase to the nucleus of unstimulated rat basophilic leukemia cells
    • Brock, TG, Paine, RR III, Peters-Golden, M. Localization of 5-lipoxygenase to the nucleus of unstimulated rat basophilic leukemia cells. J. Biol. Chem. 1994; 269: 22 059–66.
    • (1994) J. Biol. Chem. , vol.269 , Issue.22
    • Brock, T.G.1    Paine, R.R.2    Peters-Golden, M.3
  • 39
    • 0029994949 scopus 로고    scopus 로고
    • Mechanisms of PAF-induced lipid body formation: A central role for 5-lipoxygenase in the compartmentalization of leukocyte lipids
    • Bozza, PT, Payne, JL, Goulet, JL, Weller, PF. Mechanisms of PAF-induced lipid body formation: A central role for 5-lipoxygenase in the compartmentalization of leukocyte lipids. J. Exp. Med. 1996; 183: 1515–25.
    • (1996) J. Exp. Med. , vol.183
    • Bozza, P.T.1    Payne, J.L.2    Goulet, J.L.3    Weller, P.F.4
  • 40
    • 0016388999 scopus 로고
    • Correlation of renal medullary prostaglandin content and renal interstitial cell lipid droplets
    • Comai, K, Prose, P, Farber, SJ. Correlation of renal medullary prostaglandin content and renal interstitial cell lipid droplets. Prostaglandins 1974; 6: 375–9.
    • (1974) Prostaglandins , vol.6
    • Comai, K.1    Prose, P.2    Farber, S.J.3
  • 41
    • 0021083544 scopus 로고
    • Lipid bodies: Cytoplasmic organelles important to arachidonate metabolism in macrophages and mast cells
    • Dvorak, AM, Dvorak, HF, Peters, SP et al. Lipid bodies: Cytoplasmic organelles important to arachidonate metabolism in macrophages and mast cells. J. Immunol. 1983; 131: 2965–76.
    • (1983) J. Immunol. , vol.131
    • Dvorak, A.M.1    Dvorak, H.F.2    Peters, S.P.3
  • 42
    • 0021719777 scopus 로고
    • Differences in the behavior of cytoplasmic granules and lipid bodies during human lung mast cell degranulation
    • Dvorak, AM, Hammel, I, Schulman, ES et al. Differences in the behavior of cytoplasmic granules and lipid bodies during human lung mast cell degranulation. J. Cell Biol. 1984; 99: 1678–87.
    • (1984) J. Cell Biol. , vol.99
    • Dvorak, A.M.1    Hammel, I.2    Schulman, E.S.3
  • 43
    • 0026020292 scopus 로고
    • Cytoplasmic lipid bodies of human eosinophils: Subcellular isolation and analysis of arachidonate incorporation
    • Weller, PF, Monahan-Earley, RA, Dvorak, HF, Dvorak, AM. Cytoplasmic lipid bodies of human eosinophils: Subcellular isolation and analysis of arachidonate incorporation. Am. J. Pathol. 1991; 138: 141–8.
    • (1991) Am. J. Pathol. , vol.138
    • Weller, P.F.1    Monahan-Earley, R.A.2    Dvorak, H.F.3    Dvorak, A.M.4
  • 44
    • 0025778642 scopus 로고
    • Cytoplasmic lipid bodies of neutrophils: Formation induced by cis-unsaturated fatty acids and mediated by protein kinase C.
    • Weller, PF, Ryeom, SW, Picard, ST, Ackerman, SJ, Dvorak, AM. Cytoplasmic lipid bodies of neutrophils: Formation induced by cis-unsaturated fatty acids and mediated by protein kinase C. J. Cell Biol. 1991; 113: 137–46.
    • (1991) J. Cell Biol. , vol.113
    • Weller, P.F.1    Ryeom, S.W.2    Picard, S.T.3    Ackerman, S.J.4    Dvorak, A.M.5
  • 46
    • 0027478599 scopus 로고
    • Stimulation of prostaglandin synthesis by human endothelial cells exposed to hypoxia
    • Michiels, C, Arnould, T, Knott, I, Dieu, M, Remade, J. Stimulation of prostaglandin synthesis by human endothelial cells exposed to hypoxia. Am. J. Physiol. 1993; 264: C866–74.
    • (1993) Am. J. Physiol. , vol.264 , pp. C866-74
    • Michiels, C.1    Arnould, T.2    Knott, I.3    Dieu, M.4    Remade, J.5
  • 47
    • 85059048905 scopus 로고
    • Induction of cytoplasmic lipid body formation in hypoxic endothelial cells
    • Scarfo, LM, Weller, PF, Farber, HW. Induction of cytoplasmic lipid body formation in hypoxic endothelial cells. Am. Rev. Respir. Dis. 1992; 145: A838.
    • (1992) Am. Rev. Respir. Dis. , vol.145 , pp. A838
    • Scarfo, L.M.1    Weller, P.F.2    Farber, H.W.3
  • 48
    • 85059049064 scopus 로고
    • Characteristics of cytoplasmic lipid body formation in hypoxic endothelial cells
    • Scarfo, LM, Weller, PF, Tzizik, DM, Farber, HW. Characteristics of cytoplasmic lipid body formation in hypoxic endothelial cells. Am. Rev. Respir. Dis. 1993; 147: A270.
    • (1993) Am. Rev. Respir. Dis. , vol.147 , pp. A270
    • Scarfo, L.M.1    Weller, P.F.2    Tzizik, D.M.3    Farber, H.W.4
  • 50
    • 0027945466 scopus 로고
    • Role of leukotrienes revealed by targeted disruption of the 5-lipoxygenase gene
    • Chen, X-S, Sheller, JR, Johnson, EN, Funk, CD. Role of leukotrienes revealed by targeted disruption of the 5-lipoxygenase gene. Nature 1994; 372: 179–82.
    • (1994) Nature , vol.372
    • Chen, X.-S.1    Sheller, J.R.2    Johnson, E.N.3    Funk, C.D.4
  • 51
    • 0027337356 scopus 로고
    • 5-Hydroxyicosatetraenoate stimulates neutrophils by a stereospecific, G protein-linked mechanism
    • O'Flaherty, JT, Rossi, AG. 5-Hydroxyicosatetraenoate stimulates neutrophils by a stereospecific, G protein-linked mechanism. J. Biol. Chem. 1993; 268: 14 708–14.
    • (1993) J. Biol. Chem. , vol.268 , Issue.14
    • O'Flaherty, J.T.1    Rossi, A.G.2
  • 52
    • 0028089109 scopus 로고
    • NS-398, a new anti-inflammatory agent, selectively inhibits prostaglandin G/H synthase/ cyclooxygenase (Cox-2) activity in vitro
    • Futaki, N, Takahashi, S, Yokoyama, M, Arai, I, Higuchi, S, Otomo, S. NS-398, a new anti-inflammatory agent, selectively inhibits prostaglandin G/H synthase/ cyclooxygenase (Cox-2) activity in vitro. Prostaglandins 1994; 47: 55–9.
    • (1994) Prostaglandins , vol.47
    • Futaki, N.1    Takahashi, S.2    Yokoyama, M.3    Arai, I.4    Higuchi, S.5    Otomo, S.6
  • 53
    • 0023821391 scopus 로고
    • Phospholipase A, activation in human neutrophils. Differential actions of diacylglycerols and alkylacylglycerols in priming cells for stimulation by N-formyl-met-leu-phe
    • Bauldry, SA, Wykle, RL, Bass, DA. Phospholipase A, activation in human neutrophils. Differential actions of diacylglycerols and alkylacylglycerols in priming cells for stimulation by N-formyl-met-leu-phe. J. Biol. Chem. 1988; 263: 16 787–95.
    • (1988) J. Biol. Chem. , vol.263 , Issue.16
    • Bauldry, S.A.1    Wykle, R.L.2    Bass, D.A.3
  • 54
    • 0026451081 scopus 로고
    • Intracellular signaling by hydrolysis of phospholipids and activation of protein kinase C
    • Nishizuka, Y. Intracellular signaling by hydrolysis of phospholipids and activation of protein kinase C. Science 1992; 258: 607–14.
    • (1992) Science , vol.258
    • Nishizuka, Y.1
  • 55
    • 0024496831 scopus 로고
    • Choline-linked phosphoglycerides. A source of phosphatidic acid and diglycerides in stimulated neutrophils
    • Agwu, DE, McPhail, LC, Chabot, MC, Daniel, LW, Wykle, RL, McCall, CE. Choline-linked phosphoglycerides. A source of phosphatidic acid and diglycerides in stimulated neutrophils. J. Biol. Chem. 1989, 264: 1405–13.
    • (1989) J. Biol. Chem. , vol.264
    • Agwu, D.E.1    McPhail, L.C.2    Chabot, M.C.3    Daniel, L.W.4    Wykle, R.L.5    McCall, C.E.6
  • 56
    • 0024410221 scopus 로고
    • Dynamics of the diradylglycerol responses of stimulated phagocytes
    • Dougherty, RW, Dubay, GR, Niedel, JE. Dynamics of the diradylglycerol responses of stimulated phagocytes. J Biol. Chem. 1989; 264: 11 263–9.
    • (1989) J Biol. Chem. , vol.264 , Issue.11
    • Dougherty, R.W.1    Dubay, G.R.2    Niedel, J.E.3
  • 57
    • 0028923306 scopus 로고
    • Radicicol, a protein tyrosine kinase inhibitor, suppresses the expression of mitogen-inducible cyclooxygenase in macrophages stimulated with lipopolysaccharide and in experimental glomerulonephritis
    • Chanmugam, P, Feng, L, Liou, S et al. Radicicol, a protein tyrosine kinase inhibitor, suppresses the expression of mitogen-inducible cyclooxygenase in macrophages stimulated with lipopolysaccharide and in experimental glomerulonephritis. J. Biol. Chem. 1995; 270: 5418–26.
    • (1995) J. Biol. Chem. , vol.270
    • Chanmugam, P.1    Feng, L.2    Liou, S.3
  • 58
    • 0019187953 scopus 로고
    • Subcellular localization of prostaglandin-forming cyclooxygenase in Swiss mouse 3T3 fibroblasts by electron microscopic immuno-cytochemistry
    • Rollins, TE, Smith, WL. Subcellular localization of prostaglandin-forming cyclooxygenase in Swiss mouse 3T3 fibroblasts by electron microscopic immuno-cytochemistry. J. Biol. Chem. 1980; 255: 4872–5.
    • (1980) J. Biol. Chem. , vol.255
    • Rollins, T.E.1    Smith, W.L.2
  • 59
    • 0027200551 scopus 로고
    • Subcellular localization of prostaglandin endoperoxide synthase-2 in murine 3T3 cells
    • Reiger, MK, DeWitt, DL, Schindler, MS, Smith, WL. Subcellular localization of prostaglandin endoperoxide synthase-2 in murine 3T3 cells. Arch. Biochem. Biophys. 1993; 301: 439–44.
    • (1993) Arch. Biochem. Biophys. , vol.301
    • Reiger, M.K.1    DeWitt, D.L.2    Schindler, M.S.3    Smith, W.L.4
  • 60
    • 0026625760 scopus 로고
    • Ultrastructural immunogold localization of prostaglandin endoperoxide synthase (cyclooxygenase) to nonmembrane-bound cytoplasmic lipid bodies in human lung mast cells, alveolar macrophages, type II pneumocytes and neutrophils
    • Dvorak, AM, Morgan, E, Schleimer, RF, Ryeom, SW, Lichtenstein, LM, Weller, PF. Ultrastructural immunogold localization of prostaglandin endoperoxide synthase (cyclooxygenase) to nonmembrane-bound cytoplasmic lipid bodies in human lung mast cells, alveolar macrophages, type II pneumocytes and neutrophils. J. Histochem. Cytochem. 1992; 40: 759–69.
    • (1992) J. Histochem. Cytochem. , vol.40
    • Dvorak, A.M.1    Morgan, E.2    Schleimer, R.F.3    Ryeom, S.W.4    Lichtenstein, L.M.5    Weller, P.F.6
  • 61
    • 0028036932 scopus 로고
    • Prostaglandin endoperoxide synthase (cyclooxygenase): ultrastructural localization to nonmembrane-bound cytoplasmic lipid bodies in human eosinophils and murine 3T3 fibroblasts
    • Dvorak, AM, Morgan, E, Tzizik, DM, Weller, PF. Prostaglandin endoperoxide synthase (cyclooxygenase): ultrastructural localization to nonmembrane-bound cytoplasmic lipid bodies in human eosinophils and murine 3T3 fibroblasts. Int. Arch. Allergy Immunol. 1994; 105: 245–50.
    • (1994) Int. Arch. Allergy Immunol. , vol.105
    • Dvorak, A.M.1    Morgan, E.2    Tzizik, D.M.3    Weller, P.F.4
  • 62
    • 0027097094 scopus 로고
    • Human lung mast cell and alveolar macrophage cytoplasmic lipid bodies contain arachidonic acid and prostaglandin endoperoxide synthase (cyclooxygenase), the substrate and enzyme necessary for prostaglandin production
    • Dvorak, AM, Schleimer, RP, Dvorak, AM, Lichtenstein, LM, Weller, PF. Human lung mast cell and alveolar macrophage cytoplasmic lipid bodies contain arachidonic acid and prostaglandin endoperoxide synthase (cyclooxygenase), the substrate and enzyme necessary for prostaglandin production. Int. Arch. Allergy Immunol. 1992; 99: 208–17.
    • (1992) Int. Arch. Allergy Immunol. , vol.99
    • Dvorak, A.M.1    Schleimer, R.P.2    Dvorak, A.M.3    Lichtenstein, L.M.4    Weller, P.F.5
  • 63
    • 0027336050 scopus 로고
    • Ultrastructural immunogold localization of prostaglandin endoperoxide synthase (cyclooxygenase) to isolated, purified fractions of guinea pig peritoneal macrophages and line 10 hepatocarcinoma cells
    • Dvorak, AM, Weller, PF, Harvey, VS, Morgan, ES, Dvorak, HF. Ultrastructural immunogold localization of prostaglandin endoperoxide synthase (cyclooxygenase) to isolated, purified fractions of guinea pig peritoneal macrophages and line 10 hepatocarcinoma cells. Int. Arch. Allergy Immunol. 1993; 101: 136–42.
    • (1993) Int. Arch. Allergy Immunol. , vol.101
    • Dvorak, A.M.1    Weller, P.F.2    Harvey, V.S.3    Morgan, E.S.4    Dvorak, H.F.5
  • 64
    • 0020593635 scopus 로고
    • Salicylate fails to prevent the inhibitory effect of 5, 8, 11, 14-eicosatetraynoic acid on human platelet cyclo-oxygenase and lipoxygenase activities
    • Cerletti, C, Livio, M, Doni, MG, De Gaetano, G. Salicylate fails to prevent the inhibitory effect of 5, 8, 11, 14-eicosatetraynoic acid on human platelet cyclo-oxygenase and lipoxygenase activities. Biochim. Biophys. Acta 1983; 759: 125–7.
    • (1983) Biochim. Biophys. Acta , vol.759
    • Cerletti, C.1    Livio, M.2    Doni, M.G.3    De Gaetano, G.4
  • 65
    • 0022255928 scopus 로고
    • Interaction of non-steroidal anti-inflammatory drugs on platelet cyclo-oxygenase and lipoxygenase activity
    • Cerletti, C. Interaction of non-steroidal anti-inflammatory drugs on platelet cyclo-oxygenase and lipoxygenase activity. Inf. J. Tissue React. 1985; 7: 309–12.
    • (1985) Inf. J. Tissue React. , vol.7
    • Cerletti, C.1
  • 66
    • 0021135689 scopus 로고
    • The effect of aspirin on the metabolism of exogenous arachidonic acid in human polymorphonuclear leukocytes
    • Punnonen, K, Uotila, P The effect of aspirin on the metabolism of exogenous arachidonic acid in human polymorphonuclear leukocytes. Prostaglandins Leukot. Med. 1984; 15: 177–85.
    • (1984) Prostaglandins Leukot. Med. , vol.15
    • Punnonen, K.1    Uotila, P.2
  • 67
    • 0023834114 scopus 로고
    • Icosanoid production can be decreased without alterations in cellular arachidonate content or enzyme activities required for arachidonate release and icosanoid synthesis
    • Laposata, M, Kaiser, SL, Capriotti, AM. Icosanoid production can be decreased without alterations in cellular arachidonate content or enzyme activities required for arachidonate release and icosanoid synthesis. J. Biol. Chem. 1988; 263: 3266–73.
    • (1988) J. Biol. Chem. , vol.263
    • Laposata, M.1    Kaiser, S.L.2    Capriotti, A.M.3
  • 68
    • 0015147286 scopus 로고
    • Formation and disappearance of triglyceride droplets in strain L fibroblasts
    • Schneeberger, EE, Lynch, RD, Geyer, RP Formation and disappearance of triglyceride droplets in strain L fibroblasts. Exp. Cell Res. 1971; 69: 193–206.
    • (1971) Exp. Cell Res. , vol.69 , pp. 193-206
    • Schneeberger, E.E.1    Lynch, R.D.2    Geyer, R.P.3
  • 70
    • 0021677049 scopus 로고
    • Effects of exogenous arachidonic, eicosapentaenoic, and docosahexaenoic acids on the generation of 5-lipoxygenase pathway products by ionophore-activated human neutrophils
    • Lee, TH, Mencia-Huerta, J-M, Shih, C, Corey, EJ, Lewis, RA, Austen, KF. Effects of exogenous arachidonic, eicosapentaenoic, and docosahexaenoic acids on the generation of 5-lipoxygenase pathway products by ionophore-activated human neutrophils. J. Clin. Invest. 1984; 74: 1922–33.
    • (1984) J. Clin. Invest. , vol.74
    • Lee, T.H.1    Mencia-Huerta, J.-M.2    Shih, C.3    Corey, E.J.4    Lewis, R.A.5    Austen, K.F.6
  • 71
    • 0023202210 scopus 로고
    • 4by human neutrophils: Involvement of protein kinase C activation in regulation of the 5-lipoxygenase pathway
    • 4by human neutrophils: Involvement of protein kinase C activation in regulation of the 5-lipoxygenase pathway. J. Immunol. 1987; 138: 3396–402.
    • (1987) J. Immunol. , vol.138
    • Liles, W.C.1    Meier, K.E.2    Henderson, W.R.3
  • 72
    • 0023229625 scopus 로고
    • Stimulation of 5-lipoxygenase activity in polymorphonuclear leukocytes of rats by caseinate treatment
    • Chang, WC, Su, GW. Stimulation of 5-lipoxygenase activity in polymorphonuclear leukocytes of rats by caseinate treatment. Biochem Pharmacol. 1987; 36: 3033–6.
    • (1987) Biochem Pharmacol. , vol.36
    • Chang, W.C.1    Su, G.W.2
  • 74
    • 0029135377 scopus 로고
    • Ultrastructural immunogold localization of subcellular sites of TNF-α in colonic Crohn's disease
    • Beil, WJ, Weller, PF, Peppercorn, MA, Dvorak, AM. Ultrastructural immunogold localization of subcellular sites of TNF-α in colonic Crohn's disease. J. Leukocyte Biol. 1995; 58: 284–98.
    • (1995) J. Leukocyte Biol. , vol.58
    • Beil, W.J.1    Weller, P.F.2    Peppercorn, M.A.3    Dvorak, A.M.4
  • 75
    • 0027525264 scopus 로고
    • Ultrastructural immunogold localization of tumor necrosis factor to the matrix compartment of human eosinophil secondary granules
    • Beil, WJ, Weller, PF, Tzizik, DM, Galli, SJ, Dvorak, AM. Ultrastructural immunogold localization of tumor necrosis factor to the matrix compartment of human eosinophil secondary granules. J. Histochem. Cytochem. 1993; 41: 1611–15.
    • (1993) Histochem. Cytochem. , vol.41
    • Beil, W.J.1    Weller, P.F.2    Tzizik, D.M.3    Galli, S.J.4    Dvorak, A.M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.