Cardiac Autonomic Dysfunction and Incidence of Atrial Fibrillation: Results From 20 Years Follow-Up

Journal of the American College of Cardiology

Volumn 69, Issue 3, 2017, Pages 291-299

  Agarwal, Sunil K ^a,b   Norby, Faye L ^c   Whitsel, Eric A ^d   Soliman, Elsayed Z ^e   Chen, Lin Y ^f   Loehr, Laura R ^d   Fuster, Valentin ^a   Heiss, Gerardo ^d   Coresh, Josef ^b   Alonso, Alvaro ^g  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF MINNESOTA   (United States)

^d UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^e WAKE FOREST SCHOOL OF MEDICINE   (United States)

^f UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

^g EMORY UNIVERSITY   (United States)

Author keywords

arrhythmia; frequency; heart rate variability; parasympathetic; sympathetic

Indexed keywords

ADULT; ARTICLE; ATRIAL FIBRILLATION; AUTONOMIC DYSFUNCTION; COHORT ANALYSIS; CONTROLLED STUDY; DEATH CERTIFICATE; ELECTROCARDIOGRAM; FEMALE; FOLLOW UP; HEART RATE; HEART RATE VARIABILITY; HOSPITAL DISCHARGE; HUMAN; MAJOR CLINICAL STUDY; MALE; PARASYMPATHETIC TONE; SYMPATHETIC TONE; AUTONOMIC NEUROPATHY; COMPLICATION; ELECTROCARDIOGRAPHY; HEART DISEASE; MIDDLE AGED; PATHOPHYSIOLOGY;

ADULT; ATRIAL FIBRILLATION; AUTONOMIC NERVOUS SYSTEM DISEASES; ELECTROCARDIOGRAPHY; FEMALE; FOLLOW-UP STUDIES; HEART DISEASES; HEART RATE; HUMANS; MALE; MIDDLE AGED;

EID: 85009999717     PISSN: 07351097     EISSN: 15583597     Source Type: Journal    
DOI: 10.1016/j.jacc.2016.10.059     Document Type: Article

References (43)

1. 1 Mozaffarian, D., Benjamin, E.J., Go, A.S., et al. Heart disease and stroke statistics—2016 update: a report from the American Heart Association. Circulation 133 (2016), e38–e360.
2. 2 Huxley, R.R., Lopez, F.L., Folsom, A.R., et al. Absolute and attributable risks of atrial fibrillation in relation to optimal and borderline risk factors: the Atherosclerosis Risk in Communities (ARIC) study. Circulation 123 (2011), 1501–1508.
3. 3 Benjamin, E.J., Chen, P.S., Bild, D.E., et al. Prevention of atrial fibrillation: report from a national heart, lung, and blood institute workshop. Circulation 119 (2009), 606–618.
4. 4 Coumel, P., Paroxysmal atrial fibrillation: a disorder of autonomic tone?. Eur Heart J 15 Suppl A (1994), 9–16.
5. 5 Malik, M., Camm, A.J., Components of heart rate variability–what they really mean and what we really measure. Am J Cardiol 72 (1993), 821–822.
6. 6 Chen, P.S., Chen, L.S., Fishbein, M.C., Lin, S.F., Nattel, S., Role of the autonomic nervous system in atrial fibrillation: pathophysiology and therapy. Circ Res 114 (2014), 1500–1515.
7. 7 Lu, Z., Scherlag, B.J., Lin, J., et al. Atrial fibrillation begets atrial fibrillation: autonomic mechanism for atrial electrical remodeling induced by short-term rapid atrial pacing. Circ Arrhythm Electrophysiol 1 (2008), 184–192.
8. 8 Bettoni, M., Zimmermann, M., Autonomic tone variations before the onset of paroxysmal atrial fibrillation. Circulation 105 (2002), 2753–2759.
9. 9 Amar, D., Zhang, H., Miodownik, S., Kadish, A.H., Competing autonomic mechanisms precede the onset of postoperative atrial fibrillation. J Am Coll Cardiol 42 (2003), 1262–1268.
10. 10 Calkins, H., Kuck, K.H., Cappato, R., et al. 2012 HRS/EHRA/ECAS expert consensus statement on catheter and surgical ablation of atrial fibrillation: recommendations for patient selection, procedural techniques, patient management and follow-up, definitions, endpoints, and research trial design. Heart Rhythm 9 (2012), 632–696.e21.
11. 11 Singh, J.P., Larson, M.G., Levy, D., Evans, J.C., Tsuji, H., Benjamin, E.J., Is baseline autonomic tone associated with new onset atrial fibrillation? Insights from the Framingham Heart Study. Ann Noninvasive Electrocardiol 9 (2004), 215–220.
12. 12 Perkiomaki, J., Ukkola, O., Kiviniemi, A., et al. Heart rate variability findings as a predictor of atrial fibrillation in middle-aged population. J Cardiovasc Electrophysiol 25 (2014), 719–724.
13. 13 Agarwal, S.K., Alonso, A., Whelton, S.P., et al. Orthostatic change in blood pressure and incidence of atrial fibrillation: results from a bi-ethnic population based study. PloS One, 8, 2013, e79030.
14. 14 The Atherosclerosis Risk in Communities (ARIC) Study: design and objectives. The ARIC investigators. Am J Epidemiol 129 (1989), 687–702.
15. 15 Liao, D., Barnes, R.W., Chambless, L.E., Heiss, G., A computer algorithm to impute interrupted heart rate data for the spectral analysis of heart rate variability–the ARIC study. Comput Biomed Res 29 (1996), 140–151.
16. 16 Liao, D., Barnes, R.W., Chambless, L.E., Simpson, R.J. Jr., Sorlie, P., Heiss, G., Age, race, and sex differences in autonomic cardiac function measured by spectral analysis of heart rate variability–the ARIC study. Atherosclerosis Risk in Communities. Am J Cardiol 76 (1995), 906–912.
17. 17 National Heart, Lung, and Blood Institute. The ARIC Manuals of Operation: no. 11. Sitting blood pressure and postural changes in blood pressure and heart rate. 1987, ARIC Coordinating Center, School of Public Health, University of North Carolina, Chapel Hill, NC.
18. 18 Schroeder, E.B., Whitsel, E.A., Evans, G.W., Prineas, R.J., Chambless, L.E., Heiss, G., Repeatability of heart rate variability measures. J Electrocardiol 37 (2004), 163–172.
19. 19 Alonso, A., Agarwal, S.K., Soliman, E.Z., et al. Incidence of atrial fibrillation in whites and African-Americans: the Atherosclerosis Risk in Communities (ARIC) study. Am Heart J 158 (2009), 111–117.
20. 20 [No authors listed]Heart rate variability. Standards of measurement, physiological interpretation, and clinical use. Task Force of the European Society of Cardiology and the North American Society of Pacing and Electrophysiology. Eur Heart J 17 (1996), 354–381.
21. 21 Alonso, A., Roetker, N.S., Soliman, E.Z., et al. Prediction of atrial fibrillation in a racially diverse cohort: the Multi-Ethnic Study of Atherosclerosis (MESA). J Am Heart Assoc, Feb 2016 [E-pub ahead of print].
22. 22 Moak, J.P., Goldstein, D.S., Eldadah, B.A., et al. Supine low-frequency power of heart rate variability reflects baroreflex function, not cardiac sympathetic innervation. Heart Rhythm 4 (2007), 1523–1529.
23. 23 Okin, P.M., Wachtell, K., Kjeldsen, S.E., et al. Incidence of atrial fibrillation in relation to changing heart rate over time in hypertensive patients: the LIFE study. Circ Arrhythm Electrophysiol 1 (2008), 337–343.
24. 24 Grundvold, I., Skretteberg, P.T., Liestol, K., et al. Low heart rates predict incident atrial fibrillation in healthy middle-aged men. Circ Arrhythm Electrophysiol 6 (2013), 726–731.
25. 25 Kalman, J.M., Munawar, M., Howes, L.G., et al. Atrial fibrillation after coronary artery bypass grafting is associated with sympathetic activation. Ann Thorac Surg 60 (1995), 1709–1715.
26. 26 Bauernschmitt, R., Malberg, H., Wessel, N., et al. Autonomic control in patients experiencing atrial fibrillation after cardiac surgery. Pacing Clin Electrophysiol 30 (2007), 77–84.
27. 27 Kalisnik, J.M., Hrovat, E., Hrastovec, A., Avbelj, V., Zibert, J., Gersak, B., Severe cardiac autonomic derangement and altered ventricular repolarization pave the way to postoperative atrial fibrillation. Innovations (Phila) 10 (2015), 398–405.
28. 28 Coumel, P., Autonomic influences of atrial fibrillation. Malik, M., Camm, A.J., (eds.) Dynamic electrocardiography, 2004, Futura, Elmsford, NY, 530–536.
29. 29 Hillebrand, S., Gast, K.B., de Mutsert, R., et al. Heart rate variability and first cardiovascular event in populations without known cardiovascular disease: meta-analysis and dose-response meta-regression. Europace 15 (2013), 742–749.
30. 30 Dekker, J.M., Crow, R.S., Folsom, A.R., et al. Low heart rate variability in a 2-minute rhythm strip predicts risk of coronary heart disease and mortality from several causes: the ARIC Study. Atherosclerosis Risk In Communities. Circulation 102 (2000), 1239–1244.
31. 31 Schauerte, P., Scherlag, B.J., Pitha, J., et al. Catheter ablation of cardiac autonomic nerves for prevention of vagal atrial fibrillation. Circulation 102 (2000), 2774–2780.
32. 32 Aistrup, G.L., Villuendas, R., Ng, J., et al. Targeted G-protein inhibition as a novel approach to decrease vagal atrial fibrillation by selective parasympathetic attenuation. Cardiovasc Res 83 (2009), 481–492.
33. 33 Miyanaga, S., Yamane, T., Date, T., et al. Impact of pulmonary vein isolation on the autonomic modulation in patients with paroxysmal atrial fibrillation and prolonged sinus pauses. Europace 11 (2009), 576–581.
34. 34 Pappone, C., Santinelli, V., Manguso, F., et al. Pulmonary vein denervation enhances long-term benefit after circumferential ablation for paroxysmal atrial fibrillation. Circulation 109 (2004), 327–334.
35. 35 Miyakoshi, M., Ikeda, T., Miwa, Y., et al. Quantitative assessment of cibenzoline administration for vagally mediated paroxysmal atrial fibrillation using frequency-domain heart rate variability analysis. J Cardiol 54 (2009), 86–92.
36. 36 White, C.M., Sander, S., Coleman, C.I., et al. Impact of epicardial anterior fat pad retention on postcardiothoracic surgery atrial fibrillation incidence: the AFIST-III Study. J Am Coll Cardiol 49 (2007), 298–303.
37. 37 Fedorowski, A., Hedblad, B., Engstrom, G., Gustav Smith, J., Melander, O., Orthostatic hypotension and long-term incidence of atrial fibrillation: the Malmo Preventive Project. J Intern Med 268 (2010), 383–389.
38. 38 Miller, J.D., Aronis, K.N., Chrispin, J., et al. Obesity, exercise, obstructive sleep apnea, and modifiable atherosclerotic cardiovascular disease risk factors in atrial fibrillation. J Am Coll Cardiol 66 (2015), 2899–2906.
39. 39 Rajendran, P.S., Buch, E., Shivkumar, K., Marshaling the autonomic nervous system for treatment of atrial fibrillation. J Am Coll Cardiol 63 (2014), 1902–1903.
40. 40 Liu, S., Jing, Y., Zhang, J., Bian, C., Zhang, Y.U., Zhang, X., Does anterior fat pad removal reduce the incidence of atrial fibrillation after CABG? A meta-analysis of randomized controlled trials. Pacing Clin Electrophysiol 38 (2015), 1363–1368.
41. 41 Giannopoulos, G., Kossyvakis, C., Efremidis, M., et al. Central sympathetic inhibition to reduce postablation atrial fibrillation recurrences in hypertensive patients: a randomized, controlled study. Circulation 130 (2014), 1346–1352.
42. 42 Krul, S.P.J., Berger, W.R., Veldkamp, M.W., et al. Treatment of atrial and ventricular arrhythmias through autonomic modulation. J Am Coll Cardiol EP 1 (2015), 496–508.
43. 43 Chen, P.S., Tan, A.Y., Autonomic nerve activity and atrial fibrillation. Heart Rhythm 4 (2007), S61–S64.