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Volumn 35, Issue 2, 2017, Pages 127-130

MARIANNE: Impact on current treatment ofhuman epidermal growth factor receptor 2-positive metastatic breast cancer and implications for the future

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; CAPECITABINE; CARBOPLATIN; DOCETAXEL; LAPATINIB; NERATINIB; PERTUZUMAB; TRASTUZUMAB; TRASTUZUMAB EMTANSINE; TUCATINIB; EPIDERMAL GROWTH FACTOR RECEPTOR 2; ERBB2 PROTEIN, HUMAN; MAYTANSINE; MONOCLONAL ANTIBODY; TAXOID;

EID: 85009769686     PISSN: 0732183X     EISSN: 15277755     Source Type: Journal    
DOI: 10.1200/JCO.2016.70.2712     Document Type: Review
Times cited : (4)

References (34)
  • 1
    • 0035869407 scopus 로고    scopus 로고
    • Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2
    • Slamon DJ, Leyland-Jones B, Shak S, et al: Use of chemotherapy plus a monoclonal antibody against HER2 for metastatic breast cancer that overexpresses HER2. N Engl J Med 344:783-792, 2001.
    • (2001) N Engl J Med , vol.344 , pp. 783-792
    • Slamon, D.J.1    Leyland-Jones, B.2    Shak, S.3
  • 2
    • 33845886440 scopus 로고    scopus 로고
    • Lapatinib plus capecitabine for HER2- positive advanced breast cancer
    • Geyer CE, Forster J, Lindquist D, et al: Lapatinib plus capecitabine for HER2- positive advanced breast cancer. N Engl J Med 355:2733-2743, 2006.
    • (2006) N Engl J Med , vol.355 , pp. 2733-2743
    • Geyer, C.E.1    Forster, J.2    Lindquist, D.3
  • 3
    • 84862914692 scopus 로고    scopus 로고
    • Pertuzumab plus trastuzumab plus docetaxel for metastatic breast cancer
    • Baselga J, Cortés J, Kim SB, et al: Pertuzumab plus trastuzumab plus docetaxel for metastatic breast cancer. N Engl J Med 366:109-119, 2012.
    • (2012) N Engl J Med , vol.366 , pp. 109-119
    • Baselga, J.1    Cortés, J.2    Kim, S.B.3
  • 4
    • 84868520609 scopus 로고    scopus 로고
    • Trastuzumab emtansine for HER2-positive advanced breast cancer
    • Verma S, Miles D, Gianni L, et al: Trastuzumab emtansine for HER2-positive advanced breast cancer. N Engl J Med 367:1783-1791, 2012.
    • (2012) N Engl J Med , vol.367 , pp. 1783-1791
    • Verma, S.1    Miles, D.2    Gianni, L.3
  • 5
    • 84905842097 scopus 로고    scopus 로고
    • Systemic therapy for patients with advanced human epidermal growth factor receptor 2-positive breast cancer: American Society of Clinical Oncology clinical practice guideline
    • Giordano SH, Temin S, Kirshner JJ, et al: Systemic therapy for patients with advanced human epidermal growth factor receptor 2-positive breast cancer: American Society of Clinical Oncology clinical practice guideline. J Clin Oncol 32: 2078-2099, 2014.
    • (2014) J Clin Oncol , vol.32 , pp. 2078-2099
    • Giordano, S.H.1    Temin, S.2    Kirshner, J.J.3
  • 6
    • 84876011018 scopus 로고    scopus 로고
    • Phase II randomized study of trastuzumab emtansine versus trastuzumab plus docetaxel in patients with human epidermal growth factor receptor 2-positive metastatic breast cancer
    • Hurvitz SA, Dirix L, Kocsis J, et al: Phase II randomized study of trastuzumab emtansine versus trastuzumab plus docetaxel in patients with human epidermal growth factor receptor 2-positive metastatic breast cancer. J Clin Oncol 31: 1157-1163, 2013.
    • (2013) J Clin Oncol , vol.31 , pp. 1157-1163
    • Hurvitz, S.A.1    Dirix, L.2    Kocsis, J.3
  • 7
    • 84902973417 scopus 로고    scopus 로고
    • Phase IIa trial of trastuzumab emtansine with pertuzumab for patients with human epidermal growth factor receptor 2-positive, locally advanced, or metastatic breast cancer
    • Miller KD, Diéras V, Harbeck N, et al: Phase IIa trial of trastuzumab emtansine with pertuzumab for patients with human epidermal growth factor receptor 2-positive, locally advanced, or metastatic breast cancer. J Clin Oncol 32: 1437-1444, 2014.
    • (2014) J Clin Oncol , vol.32 , pp. 1437-1444
    • Miller, K.D.1    Diéras, V.2    Harbeck, N.3
  • 8
    • 85009887737 scopus 로고    scopus 로고
    • Trastuzumab emtansine with or without pertuzumab versus trastuzumab plus taxane for human epidermal growth factor receptor 2-positive advanced breast cancer: Primary results from the phase III MARIANNE study
    • Perez EA, Barrios C, Eiermann W, et al: Trastuzumab emtansine with or without pertuzumab versus trastuzumab plus taxane for human epidermal growth factor receptor 2-positive advanced breast cancer: Primary results from the phase III MARIANNE study. J Clin Oncol 35:141-148, 2017.
    • (2017) J Clin Oncol , vol.35 , pp. 141-148
    • Perez, E.A.1    Barrios, C.2    Eiermann, W.3
  • 9
    • 84879477431 scopus 로고    scopus 로고
    • AVEREL: A randomized phase III Trial evaluating bevacizumab in combination with docetaxel and trastuzumab as first-line therapy for HER2-positive locally recurrent/metastatic breast cancer
    • Gianni L, Romieu GH, Lichinitser M, et al: AVEREL: A randomized phase III Trial evaluating bevacizumab in combination with docetaxel and trastuzumab as first-line therapy for HER2-positive locally recurrent/metastatic breast cancer. J Clin Oncol 31:1719-1725, 2013.
    • (2013) J Clin Oncol , vol.31 , pp. 1719-1725
    • Gianni, L.1    Romieu, G.H.2    Lichinitser, M.3
  • 10
    • 84937523280 scopus 로고    scopus 로고
    • Combination of everolimus with trastuzumab plus paclitaxel as first-line treatment for patients with HER2-positive advanced breast cancer (BOLERO-1): A phase 3, randomised, double-blind, multicentre trial
    • Hurvitz SA, Andre F, Jiang Z, et al: Combination of everolimus with trastuzumab plus paclitaxel as first-line treatment for patients with HER2-positive advanced breast cancer (BOLERO-1): A phase 3, randomised, double-blind, multicentre trial. Lancet Oncol 16:816-829, 2015.
    • (2015) Lancet Oncol , vol.16 , pp. 816-829
    • Hurvitz, S.A.1    Andre, F.2    Jiang, Z.3
  • 11
    • 79951982754 scopus 로고    scopus 로고
    • Multicenter phase III randomized trial comparing docetaxel and trastuzumab with docetaxel, carboplatin, and trastuzumab as first-line chemotherapy for patients with HER2-gene-amplified metastatic breast cancer (BCIRG 007 study): Two highly active therapeutic regimens
    • Valero V, Forbes J, Pegram MD, et al: Multicenter phase III randomized trial comparing docetaxel and trastuzumab with docetaxel, carboplatin, and trastuzumab as first-line chemotherapy for patients with HER2-gene-amplified metastatic breast cancer (BCIRG 007 study): Two highly active therapeutic regimens. J Clin Oncol 29:149-156, 2011.
    • (2011) J Clin Oncol , vol.29 , pp. 149-156
    • Valero, V.1    Forbes, J.2    Pegram, M.D.3
  • 12
    • 79951974161 scopus 로고    scopus 로고
    • Phase III randomized study comparing docetaxel plus trastuzumab with vinorelbine plus trastuzumab as firstline therapy of metastatic or locally advanced human epidermal growth factor receptor 2-positive breast cancer: The HERNATA study
    • Andersson M, Lidbrink E, Bjerre K, et al: Phase III randomized study comparing docetaxel plus trastuzumab with vinorelbine plus trastuzumab as firstline therapy of metastatic or locally advanced human epidermal growth factor receptor 2-positive breast cancer: The HERNATA study. J Clin Oncol 29:264-271, 2011.
    • (2011) J Clin Oncol , vol.29 , pp. 264-271
    • Andersson, M.1    Lidbrink, E.2    Bjerre, K.3
  • 13
    • 84923052492 scopus 로고    scopus 로고
    • Pertuzumab, trastuzumab, and docetaxel in HER2-positive metastatic breast cancer
    • Swain SM, Baselga J, Kim S-B, et al: Pertuzumab, trastuzumab, and docetaxel in HER2-positive metastatic breast cancer. N Engl J Med 372:724-734, 2015.
    • (2015) N Engl J Med , vol.372 , pp. 724-734
    • Swain, S.M.1    Baselga, J.2    Kim, S.-B.3
  • 14
    • 34347395733 scopus 로고    scopus 로고
    • Trastuzumab-Mechanism of action and use in clinical practice
    • Hudis CA: Trastuzumab-Mechanism of action and use in clinical practice. N Engl J Med 357:39-51, 2007.
    • (2007) N Engl J Med , vol.357 , pp. 39-51
    • Hudis, C.A.1
  • 15
    • 56449129810 scopus 로고    scopus 로고
    • Targeting HER2-positive breast cancer with trastuzumab-DM1, an antibody-cytotoxic drug conjugate
    • Lewis Phillips GD, Li G, Dugger DL, et al: Targeting HER2-positive breast cancer with trastuzumab-DM1, an antibody-cytotoxic drug conjugate. Cancer Res 68:9280-9290, 2008.
    • (2008) Cancer Res , vol.68 , pp. 9280-9290
    • Lewis Phillips, G.D.1    Li, G.2    Dugger, D.L.3
  • 16
    • 85009769121 scopus 로고    scopus 로고
    • Pathologic complete response (PCR) rates after neoadjuvant trastuzumab emtansine (T-DM1 [K]) 1 pertuzumab (P) vs docetaxel 1 carboplatin 1 trastuzumab 1 P (TCHP) treatment in patients with HER2-positive (HER21) early breast cancer (EBC) (KRISTINE)
    • suppl; abstr 500
    • Hurvitz SA, Martin M, Symmans WF, et al: Pathologic complete response (pCR) rates after neoadjuvant trastuzumab emtansine (T-DM1 [K]) 1 pertuzumab (P) vs docetaxel 1 carboplatin 1 trastuzumab 1 P (TCHP) treatment in patients with HER2-positive (HER21) early breast cancer (EBC) (KRISTINE). J Clin Oncol 34, 2016 (suppl; abstr 500).
    • (2016) J Clin Oncol , vol.34
    • Hurvitz, S.A.1    Martin, M.2    Symmans, W.F.3
  • 17
    • 79952092706 scopus 로고    scopus 로고
    • Phase II study of the antibody drug conjugate trastuzumab-DM1 for the treatment of human epidermal growth factor receptor 2 (HER2)-positive breast cancer after prior HER2-directed therapy
    • Burris HA III, Rugo HS, Vukelja SJ, et al: Phase II study of the antibody drug conjugate trastuzumab-DM1 for the treatment of human epidermal growth factor receptor 2 (HER2)-positive breast cancer after prior HER2-directed therapy. J Clin Oncol 29:398-405, 2011.
    • (2011) J Clin Oncol , vol.29 , pp. 398-405
    • Burris, H.A.1    Rugo, H.S.2    Vukelja, S.J.3
  • 18
    • 84964307819 scopus 로고    scopus 로고
    • High HER2 expression correlates with response to the combination of lapatinib and trastuzumab
    • Scaltriti M, Nuciforo P, Bradbury I, et al: High HER2 expression correlates with response to the combination of lapatinib and trastuzumab. Clin Cancer Res 21: 569-576, 2015.
    • (2015) Clin Cancer Res , vol.21 , pp. 569-576
    • Scaltriti, M.1    Nuciforo, P.2    Bradbury, I.3
  • 19
    • 84904343628 scopus 로고    scopus 로고
    • Relationship between HER2 expression and efficacy with first-line trastuzumab emtansine compared with trastuzumab plus docetaxel in TDM4450g: A randomized phase II study of patients with previously untreated HER2-positive metastatic breast cancer
    • Perez EA, Hurvitz SA, Amler LC, et al: Relationship between HER2 expression and efficacy with first-line trastuzumab emtansine compared with trastuzumab plus docetaxel in TDM4450g: A randomized phase II study of patients with previously untreated HER2-positive metastatic breast cancer. Breast Cancer Res 16:R50, 2014.
    • (2014) Breast Cancer Res , vol.16 , pp. R50
    • Perez, E.A.1    Hurvitz, S.A.2    Amler, L.C.3
  • 20
    • 84911926434 scopus 로고    scopus 로고
    • Biomarker analyses in CLEOPATRA: A phase III, placebo-controlled study of pertuzumab in human epidermal growth factor receptor 2-positive, first-line metastatic breast cancer
    • Baselga J, Cortés J, Im SA, et al: Biomarker analyses in CLEOPATRA: A phase III, placebo-controlled study of pertuzumab in human epidermal growth factor receptor 2-positive, first-line metastatic breast cancer. J Clin Oncol 32: 3753-3761, 2014.
    • (2014) J Clin Oncol , vol.32 , pp. 3753-3761
    • Baselga, J.1    Cortés, J.2    Im, S.A.3
  • 21
    • 84896776546 scopus 로고    scopus 로고
    • Trastuzumab emtansine: Mechanisms of action and drug resistance
    • Barok M, Joensuu H, Isola J: Trastuzumab emtansine: Mechanisms of action and drug resistance. Breast Cancer Res 16:209, 2014.
    • (2014) Breast Cancer Res , vol.16 , pp. 209
    • Barok, M.1    Joensuu, H.2    Isola, J.3
  • 22
    • 84892168048 scopus 로고    scopus 로고
    • Trastuzumab emtansine: A novel antibody-drug conjugate for HER2-positive breast cancer
    • Krop I, Winer EP: Trastuzumab emtansine: A novel antibody-drug conjugate for HER2-positive breast cancer. Clin Cancer Res 20:15-20, 2014.
    • (2014) Clin Cancer Res , vol.20 , pp. 15-20
    • Krop, I.1    Winer, E.P.2
  • 23
    • 84906819100 scopus 로고    scopus 로고
    • Trastuzumab emtansine in human epidermal growth factor receptor 2-positive metastatic breast cancer: An integrated safety analysis
    • Diéras V, Harbeck N, Budd GT, et al: Trastuzumab emtansine in human epidermal growth factor receptor 2-positive metastatic breast cancer: An integrated safety analysis. J Clin Oncol 32:2750-2757, 2014.
    • (2014) J Clin Oncol , vol.32 , pp. 2750-2757
    • Diéras, V.1    Harbeck, N.2    Budd, G.T.3
  • 24
    • 84901639476 scopus 로고    scopus 로고
    • Trastuzumab emtansine versus treatment of physician's choice for pretreated HER2-positive advanced breast cancer (TH3RESA): A randomised, open-label, phase 3 trial
    • Krop IE, Kim SB, Gonźalez-Martín A, et al: Trastuzumab emtansine versus treatment of physician's choice for pretreated HER2-positive advanced breast cancer (TH3RESA): A randomised, open-label, phase 3 trial. Lancet Oncol 15: 689-699, 2014.
    • (2014) Lancet Oncol , vol.15 , pp. 689-699
    • Krop, I.E.1    Kim, S.B.2    Gonźalez-Martín, A.3
  • 25
    • 84922384344 scopus 로고    scopus 로고
    • Phase II study of paclitaxel given once per week along with trastuzumab and pertuzumab in patients with human epidermal growth factor receptor 2-positive metastatic breast cancer
    • Dang C, Iyengar N, Datko F, et al: Phase II study of paclitaxel given once per week along with trastuzumab and pertuzumab in patients with human epidermal growth factor receptor 2-positive metastatic breast cancer. J Clin Oncol 33: 442-447, 2015.
    • (2015) J Clin Oncol , vol.33 , pp. 442-447
    • Dang, C.1    Iyengar, N.2    Datko, F.3
  • 27
    • 78751610848 scopus 로고    scopus 로고
    • Iniparib plus chemotherapy in metastatic triple-negative breast cancer
    • O'Shaughnessy J, Osborne C, Pippen JE, et al: Iniparib plus chemotherapy in metastatic triple-negative breast cancer. N Engl J Med 364:205-214, 2011.
    • (2011) N Engl J Med , vol.364 , pp. 205-214
    • O'Shaughnessy, J.1    Osborne, C.2    Pippen, J.E.3
  • 28
    • 84912105634 scopus 로고    scopus 로고
    • Phase III study of iniparib plus gemcitabine and carboplatin versus gemcitabine and carboplatin in patients with metastatic triple-negative breast cancer
    • O'Shaughnessy J, Schwartzberg L, Danso MA, et al: Phase III study of iniparib plus gemcitabine and carboplatin versus gemcitabine and carboplatin in patients with metastatic triple-negative breast cancer. J Clin Oncol 32:3840-3847, 2014.
    • (2014) J Clin Oncol , vol.32 , pp. 3840-3847
    • O'Shaughnessy, J.1    Schwartzberg, L.2    Danso, M.A.3
  • 29
    • 84911943039 scopus 로고    scopus 로고
    • Safety and efficacy of neratinib in combination with capecitabine in patients with metastatic human epidermal growth factor receptor 2-positive breast cancer
    • Saura C, Garcia-Saenz JA, Xu B, et al: Safety and efficacy of neratinib in combination with capecitabine in patients with metastatic human epidermal growth factor receptor 2-positive breast cancer. J Clin Oncol 32:3626-3633, 2014.
    • (2014) J Clin Oncol , vol.32 , pp. 3626-3633
    • Saura, C.1    Garcia-Saenz, J.A.2    Xu, B.3
  • 30
    • 85009751929 scopus 로고    scopus 로고
    • Efficacy results of a phase 1b study of ont-380, a CNS-penetrant TKI, in combination with T-DM1 in HER21 metastatic breast cancer (MBC), including patients (pts) with brain metastases
    • suppl; abstr 513
    • Borges VF, Ferrario C, Aucoin N, et al: Efficacy results of a phase 1b study of ont-380, a CNS-penetrant TKI, in combination with T-DM1 in HER21 metastatic breast cancer (MBC), including patients (pts) with brain metastases. J Clin Oncol 34, 2016 (suppl; abstr 513).
    • (2016) J Clin Oncol , vol.34
    • Borges, V.F.1    Ferrario, C.2    Aucoin, N.3
  • 31
    • 84900434047 scopus 로고    scopus 로고
    • Pertuzumab in the treatment of HER21 breast cancer
    • Jhaveri K, Esteva FJ: Pertuzumab in the treatment of HER21 breast cancer. J Natl Compr Canc Netw 12:591-598, 2014.
    • (2014) J Natl Compr Canc Netw , vol.12 , pp. 591-598
    • Jhaveri, K.1    Esteva, F.J.2
  • 32
    • 5144226211 scopus 로고    scopus 로고
    • PTEN activation contributes to tumor inhibition by trastuzumab, and loss of PTEN predicts trastuzumab resistance in patients
    • Nagata Y, Lan KH, Zhou X, et al: PTEN activation contributes to tumor inhibition by trastuzumab, and loss of PTEN predicts trastuzumab resistance in patients. Cancer Cell 6:117-127, 2004.
    • (2004) Cancer Cell , vol.6 , pp. 117-127
    • Nagata, Y.1    Lan, K.H.2    Zhou, X.3
  • 33
    • 84980338826 scopus 로고    scopus 로고
    • Relationship between tumor biomarkers and efficacy in EMILIA, a phase III study of trastuzumab emtansine in HER2-positive metastatic breast cancer
    • Baselga J, Lewis Phillips GD, Verma S, et al: Relationship between tumor biomarkers and efficacy in EMILIA, a phase III study of trastuzumab emtansine in HER2-positive metastatic breast cancer. Clin Cancer Res 22:3755-3763, 2016.
    • (2016) Clin Cancer Res , vol.22 , pp. 3755-3763
    • Baselga, J.1    Lewis Phillips, G.D.2    Verma, S.3
  • 34
    • 84986627812 scopus 로고    scopus 로고
    • Relationship between tumor biomarkers and efficacy in TH3RESA, a phase III study of trastuzumab emtansine (T-DM1) vs. Treatment of physician's choice in previously treated HER2-positive advanced breast cancer
    • Kim SB, Wildiers H, Krop IE, et al: Relationship between tumor biomarkers and efficacy in TH3RESA, a phase III study of trastuzumab emtansine (T-DM1) vs. treatment of physician's choice in previously treated HER2-positive advanced breast cancer. Int J Cancer 139:2336-2342, 2016.
    • (2016) Int J Cancer , vol.139 , pp. 2336-2342
    • Kim, S.B.1    Wildiers, H.2    Krop, I.E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.