Drug targeting to the vitreous body and its peripheral tissues

Drug Delivery System

Volumn 11, Issue 2, 1996, Pages 133-137

  Uno, Kumiko ^a   Nakagawa, Katsunori ^a   Ohtori, Akira ^a   Tojo, Kakuji ^a  

^a KYUSHU INSTITUTE OF TECHNOLOGY   (Japan)

Author keywords

computer simulation; in vivo in vitro correlation; intravitreal delivery; ocular targeting; pharmacokinetic model

Indexed keywords

EID: 85009643398     PISSN: 09135006     EISSN: 18812732     Source Type: Journal    
DOI: 10.2745/dds.11.133     Document Type: Article

References (6)

1. Smith, T.J., Pearson, P.A., Blandford, D.L., Brown, J.D., Gains, K.A. et al. : Intravitreal sustained-release ganciclovir. Arch. Ophthalmol. 110 : 255-258, 1992.
2. Barrer, R.M. : Diffusion and permeation in heterogeneous media. Diffusion in Polymers. (eds. Crank, J., Park, G.S.), Academic Press, New York, 1968, p 165-217.
3. Crank, J. : The mathematics of diffusion. 2nd ed. Clarendon Press, Oxford, 1975, p 230.
4. Ohtori, A., Tojo, K. : In vivo/in vitro correlation intravitreal delivery of drugs with the help of computer simulation. Biol. Pharm. Bull. 17 : 283-290, 1994.
5. Tojo, K. : Pharmacokinetic model of transcorneal drug delivery. Mathematical Biosciences 89 : 53-77, 1988.
6. Baker, R.W., Lonsdale, H.K. : Controlled release : Mechanisms and rates. Controlled Release of Biologically Active Agents. (eds. Tanquary, A.C., Lacey, R.E.), Plenum Press, New York, 1974, p 15.