Hypoxanthine promotes the acquisition of meiotic competence in pig oocytes from early antral follicles during growth culture

Journal of Mammalian Ova Research

Volumn 19, Issue 1, 2002, Pages 39-45

  Moritake, Sadanobu ^a   Hirao, Yuji ^a  

^a KOBE UNIVERSITY   (Japan)

Author keywords

Growing oocyte; Hypoxanthine; In vitro culture; Meiotic competence; Pig

Indexed keywords

EID: 85009592513     PISSN: 13417738     EISSN: 13475878     Source Type: Journal    
DOI: 10.1274/jmor.19.39     Document Type: Article

References (25)

1. Eppig, J.J. and O'Brien, M.J. (1996): Development in vitro of mouse oocytes from primordial follicles. Biol. Reprod., 54, 197-207.
2. Wade, R. (1996): Fertile results: bringing up baby (eggs). Science, 271, 594-595.
3. Hirao, Y., Nagai, T., Kubo, M., Miyano, T., Miyake, M. and Kato, S. (1994): In vitro growth and maturation of pig oocytes. J. Reprod. Fert., 100, 333-339.
4. Harada, M., Miyano, T., Matsumura, K., Osaki, S., Miyake, M. and Kato, S. (1997): Bovine oocytes from early antral follicles grow to meiotic competence in vitro: effect of FSH and hypoxanthine. Theriogenology, 48, 743-755.
5. Osaki, S., Matsumura, K., Yamamoto, K., Miyano, T., Miyake, M., and Kato, S. (1998): Fertilization of bovine oocytes grown in vitro. Reprod. Fertil. Dev., 9, 781-787.
6. Gutierrez, C.G., Ralph, J.H., Telfer, E.E., Wilmut, I. and Webb, R. (2000): Growth and antrum formation of bovine preantral follicles in long-term culture in vitro. Biol. Reprod., 62, 1322-1328.
7. Motlik, J., Crozet, N. and Fulka, J. (1984): Meiotic competence in vitro of pig oocytes isolated from early antral follicles. J. Reprod. Fert., 72, 323-328.
8. Hirao, Y., Tsuji, Y., Miyano, T., Okano, A., Miyake, M., Kato, S. and Moor, R.M. (1995): Association between p34cdc2 levels and meiotic arrest in pig oocytes during early growth. Zygote, 3, 325-332.
9. Miyano, T., Moritake, S., Hirata, K., Miyake, M. and Kato, S. (1998): In vitro culture of pig oocytes collected from early antral follicles. J. Mamm. Ova Res., 15, 161-166.
10. Hulshof, S.C.J., Figueiredo, J.R., Beckers, J.F., Bevers, M.M., van der Donk, J.A. and van den Hurk, R. (1995): Effects of fetal bovine serum, FSH and 17β-estradiol on the culture of bovine preantral follicles. Theriogenology, 44, 217-226.
11. Wandji, S.A., Epigg, J.J. and Fortune, J.E. (1996): FSH and growth factors affect the growth and endocrine function in vitro of granulosa cells of bovine preantral follicles. Theriogenology, 45, 817-832.
12. Katska, L., Alm, H. and Rynska, B. (2000): Nuclear configuration of bovine oocytes derived from fresh and in vitro-cultured preantral and early antral ovarian follicles. Theriogenology, 54, 247-260.
13. Hirao, Y., Miyano, T. and Kato, S. (1992): In vitro growth of porcine oocytes. Proceedings of 12th International Congress on Animal Reproduction, 4, 333-335.
14. Downs, S.M., Coleman, D.L., Ward-Bailey, P.F. and Eppig, J.J. (1985): Hypoxanthine is the principal inhibitor of murine oocyte maturation in a low molecular weight fraction of porcine follicular fluid. Proc. Nat. Acad. Sci. USA, 82, 454-458.
15. Eppig, J.J., Ward-Bailey, P.F. and Coleman, D.L. (1985): Hypoxanthine and adenosine in murine ovarian follicular fluid: concentrations and activity in maintaining oocyte meiotic arrest. Biol. Reprod., 33, 1041-1049.
16. Eppig, J.J. and Downs, S.M. (1987): The effect of hypoxanthine on mouse oocyte growth and development in vitro: maintenance of meiotic arrest and gonadotropininduced oocyte maturation. Dev. Biol., 119, 313-321.
17. Figueiredo, J.R., Hulshof, S.C.J., van den Hurk, R., Nusgens, B., Bevers, M.M., Ectors, F.J., and Beckers, J.F. (1994): Preservation of oocyte and granulosa cell morphology in bovine preantral follicles cultured in vitro. Theriogenology, 41, 1333-1346.
18. Motlik, J. and Fulka, J. (1976): Breakdown of the germinal vesicle in pig oocytes in vivo and in vitro. J. Exp. Zool., 198, 155-162.
19. Morbeck, D.E., Flowers, W.L. and Britt, J.H. (1993): Response of porcine granulosa cells isolated from primary and secondary follicles to FSH, 8-bromo-cAMP and epidermal growth factor in vitro. J. Reprod. Fert., 99, 577-584.
20. Richards, J.S. and Midgley, Jr. A.R. (1976): Protein hormone action: a key to understanding ovarian follicular and luteal cell development. Biol. Reprod., 14, 82-94.
21. Gore-Langton, R.E. and Armstrong, D.T. (1988): Follicular steroidogenesis and its control. In: The Physiology of Reproduction (Knobil, E. and Neill, J. eds.), pp. 331-385, Raven Press, New York.
22. Guthrie, H.D., Garrett, W.M. and Cooper, B.S. (1998): Follicle-stimulating hormone and insulin-like growth factor-I attenuate apoptosis in cultured porcine granulosa cells. Biol. Reprod., 58, 390-396.
23. Wickramasinghe, D., Ebert, K.M. and Albertini, D.F. (1991): Meiotic competence acquisition is associated with the appearance of M-phase characteristics in growing mouse oocytes. Dev. Biol., 143, 162-172.
24. Chesnel, F., Wigglesworth, K. and Eppig, J.J. (1994): Acquisition of meiotic competence by denuded mouse oocytes: participation of somatic-cell product(s) and cAMP. Dev. Biol., 161, 285-295.
25. Miyano, T., Ebihara, M., Goto, Y., Hirao, Y., Nagai, T. and Kato, S. (1995): Inhibitory action of hypoxanthine on meiotic resumption of denuded pig follicular oocytes in vitro. J. Exp. Zool., 273, 70-75.