Breast cancer screening in Denmark: A Cohort study of tumor size and overdiagnosis

Annals of Internal Medicine

Volumn 166, Issue 5, 2017, Pages 313-323

  Jørgensen, Karsten Juhl ^a   Gøtzsche, Peter C ^a   Kalager, Mette ^b   Zahl, Per Henrik ^c  

^a Rigshospitalet   (Denmark)

^b UNIVERSITY OF OSLO   (Norway)

^c NORWEGIAN INSTITUTE OF PUBLIC HEALTH   (Norway)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ADVANCED CANCER; AGED; ARTICLE; BREAST CANCER; CANCER INCIDENCE; CANCER SCREENING; CANCER SIZE; COHORT ANALYSIS; DENMARK; FEMALE; GROUPS BY AGE; HUMAN; INTRADUCTAL CARCINOMA; MAJOR CLINICAL STUDY; MAMMOGRAPHY; PRIORITY JOURNAL; TREND STUDY; TUMOR INVASION; TUMOR VOLUME; BREAST NEOPLASMS; CARCINOMA, INTRADUCTAL, NONINFILTRATING; EARLY CANCER DIAGNOSIS; HEALTH SERVICE; INCIDENCE; MASS SCREENING; MIDDLE AGED; STATISTICS AND NUMERICAL DATA; VERY ELDERLY;

ADULT; AGED; AGED, 80 AND OVER; BREAST NEOPLASMS; CARCINOMA, INTRADUCTAL, NONINFILTRATING; COHORT STUDIES; DENMARK; EARLY DETECTION OF CANCER; FEMALE; HUMANS; INCIDENCE; MAMMOGRAPHY; MASS SCREENING; MEDICAL OVERUSE; MIDDLE AGED;

EID: 85009489955     PISSN: 00034819     EISSN: 15393704     Source Type: Journal    
DOI: 10.7326/M16-0270     Document Type: Article

References (30)

1. Vainio H, Bianchini F. Breast cancer screening. In: IARC Handbooks of Cancer Prevention. Vol. 7. Lyon, France: IARC Pr; 2002.
2. American Joint Committee on Cancer. Cancer Staging Handbook. 6th ed. New York: Springer-Verlag; 2002.
3. Autier P, Boniol M, Middleton R, Doré JF, Héry C, Zheng T, et al. Advanced breast cancer incidence following population-based mammographic screening. Ann Oncol. 2011;22:1726-35. [PMID: 21252058] doi:10.1093/annonc/mdq633
4. Harding C, Pompei F, Burmistrov D, Welch HG, Abebe R, Wilson R. Breast cancer screening, incidence, and mortality across US counties. JAMA Intern Med. 2015;175:1483-9. [PMID: 26147578] doi:10 .1001/jamainternmed.2015.3043
5. Gotzsche PC, Jorgensen KJ, Zahl PH, Mahlen J. Why mammography screening has not lived up to expectations from the randomised trials. Cancer Causes Control. 2012;23:15-21. [PMID: 22072221] doi:10.1007/s10552-011-9867-8
6. Jorgensen KJ, Zahl PH, Gotzsche PC. Influence of mammography screening on use of mastectomies in Denmark [Letter]. Acta Oncol. 2015;54:133-4. [PMID: 24881500] doi:10.3109/0284186X.2014 .920958
7. Kalager M, Adami HO, Bretthauer M, Tamimi RM. Overdiagnosis of invasive breast cancer due to mammography screening: results from the Norwegian screening program. Ann Intern Med. 2012;156: 491-9. [PMID: 22473436] doi:10.7326/0003-4819-156-7-201204030 -00005
8. Lousdal ML, Kristiansen IS, Moller B, Stovring H. Trends in breast cancer stage distribution before, during and after introduction of a screening programme in Norway. Eur J Public Health. 2014;24: 1017-22. [PMID: 24596400] doi:10.1093/eurpub/cku015
9. Statens Serum Institut. Validation of the Danish Cancer Registry and selected clinical cancer databases. Accessed at http: //sundhedsdatastyrelsen.dk/-/media/sds/filer/registre-og-services /nationale-sundhedsregistre/sygedomme-laegemidler-og-behand linger/cancerregisteret/valideringsrapport-cancerregisteret-english -abstract.pdf?la=da on 15 December 2016.
10. Danmarks Statistik. Statistikbanken. 2016. Accessed at www .statistikbanken.dk/statbank5a/default.asp?w=2560 on 10 February 2015.
11. Sundhedsstyrelsen. Statusrapport. Tidlig opsporing og behandling af brystkraft. Copenhagen: Sundhedsstyrelsen; 1997.
12. Christiansen P, Vejborg I, Kroman N, Holten I, Garne JP, Vedsted P, et al. Position paper: breast cancer screening, diagnosis, and treatment in Denmark. Acta Oncol. 2014;53:433-44. [PMID: 24495043] doi:10.3109/0284186X.2013.874573
13. von Euler-Chelpin M, Olsen AH, Njor S, Vejborg I, Schwartz W, Lynge E. Women's patterns of participation in mammography screening in Denmark. Eur J Epidemiol. 2006;21:203-9. [PMID: 16547835]
14. Jensen A, Olsen AH, von Euler-Chelpin M, Helle Njor S, Vejborg I, Lynge E. Do nonattenders in mammography screening programmes seek mammography elsewhere? Int J Cancer. 2005;113: 464-70. [PMID: 15455383]
15. Zahl PH, Jorgensen KJ, Gotzsche PC. Overestimated lead times in cancer screening has led to substantial underestimation of overdiagnosis. Br J Cancer. 2013;109:2014-9. [PMID: 23963144] doi:10 .1038/bjc.2013.427
16. Njor SH, Olsen AH, Blichert-Toft M, Schwartz W, Vejborg I, Lynge E. Overdiagnosis in screening mammography in Denmark: population based cohort study. BMJ. 2013;346:f1064. [PMID: 23444414] doi:10.1136/bmj.f1064
17. Rostgaard K, Vaeth M, Rootzé n H, Lynge E. Why did the breast cancer lymph node status distribution improve in Denmark in the pre-mammography screening period of 1978-1994? Acta Oncol. 2010;49:313-21. [PMID: 20397766] doi:10.3109/02841861003602074
18. Black WC, Haggstrom DA, Welch HG. All-cause mortality in randomized trials of cancer screening. J Natl Cancer Inst. 2002;94:167-73. [PMID: 11830606]
19. Independent UK Panel on Breast Cancer Screening. The benefits and harms of breast cancer screening: an independent review. Lancet. 2012;380:1778-86. [PMID: 23117178] doi:10.1016/S0140-6736 (12)61611-0
20. Carter JL, Coletti RJ, Harris RP. Quantifying and monitoring overdiagnosis in cancer screening: a systematic review of methods. BMJ. 2015;350:g7773. [PMID: 25569206] doi:10.1136/bmj.g7773.
21. Bleyer A, Welch HG. Effect of three decades of screening mammography on breast-cancer incidence. N Engl J Med. 2012;367: 1998-2005. [PMID: 23171096] doi:10.1056/NEJMoa1206809
22. Jorgensen KJ, Gotzsche PC. Overdiagnosis in publicly organised mammography screening programmes: systematic review of incidence trends. BMJ. 2009;339:b2587. [PMID: 19589821] doi:10 .1136/bmj.b2587
23. Jorgensen KJ, Zahl PH, Gotzsche PC. Overdiagnosis in organised mammography screening in Denmark. A comparative study. BMC Womens Health. 2009;9:36. [PMID: 20028513] doi:10.1186 /1472-6874-9-36
24. Patnick J, ed. NHS Breast Screening Programme: Annual Review 2011. Sheffield, UK: NHS Breast Screening Programme; 2011.
25. Zahl PH, Mahlen J. Overdiagnosis of breast cancer after 14 years of mammography screening. Tidsskr Nor Laegeforen. 2012;132: 414-7. [PMID: 22353833] doi:10.4045/tidsskr.11.0195
26. Puliti D, Duffy SW, Miccinesi G, de Koning H, Lynge E, Zappa M, et al; Euroscreen Working Group. Overdiagnosis in mammographic screening for breast cancer in Europe: a literature review. J Med Screen. 2012;19 Suppl 1:42-56. [PMID: 22972810]
27. Francis A, Fallowfield L, Rea D. The LORIS Trial: addressing overtreatment of ductal carcinoma in situ [Editorial]. Clin Oncol (R Coll Radiol). 2015;27:6-8. [PMID: 25445552] doi:10.1016/j.clon.2014.09 .015
28. Gotzsche PC, Jorgensen KJ. Screening for breast cancer with mammography. Cochrane Database Syst Rev. 2013:CD001877. [PMID: 23737396] doi:10.1002/14651858.CD001877.pub5
29. Suhrke P, Mahlen J, Schlichting E, Jorgensen KJ, Gotzsche PC, Zahl PH. Effect of mammography screening on surgical treatment for breast cancer in Norway: comparative analysis of cancer registry data. BMJ. 2011;343:d4692. [PMID: 21914765] doi:10.1136/bmj .d4692
30. Jorgensen KJ, Zahl PH, Gotzsche PC. Breast cancer mortality in organised mammography screening in Denmark: comparative study. BMJ. 2010;340:c1241. [PMID: 20332505] doi:10.1136/bmj .c1241