Synthesis, photodynamic activity, and quantitative structure-activity relationship modelling of a series of BODIPYs

Journal of Photochemistry and Photobiology B: Biology

Volumn 167, Issue , 2017, Pages 269-281

  Caruso, Enrico ^a   Gariboldi, Marzia ^a   Sangion, Alessandro ^a   Gramatica, Paola ^a   Banfi, Stefano ^a  

^a UNIVERSITY OF INSUBRIA   (Italy)

Author keywords

BODIPY; Photodynamic therapy; QSAR; Singlet oxygen; Tumor cells

Indexed keywords

4,4 DIFLUORO 2,6 DIIODO 1,3,5,7 TETRAMETHYL 4 BORA 3A,4A DIAZA INDACENE; 4,4 DIFLUORO 2,6 DIIODO 1,3,5,7 TETRAMETHYL 8 (2' CHLORO 6' NITROPHENYL) 4 BORA 3A,4A DIAZA INDACENE; 4,4 DIFLUORO 2,6 DIIODO 1,3,5,7 TETRAMETHYL 8 (2' METHOXYPHENYL) 4 BORA 3A,4A DIAZA INDACENE; 4,4 DIFLUORO 2,6 DIIODO 1,3,5,7 TETRAMETHYL 8 (2',3',4',5',6' PENTAFLUOROPHENYL) 4 BORA 3A,4A DIAZA INDACENE; 4,4 DIFLUORO 2,6 DIIODO 1,3,5,7 TETRAMETHYL 8 (2',4',6' TRIMETHOXYPHENYL) 4 BORA 3A,4A DIAZA INDACENE; 4,4 DIFLUORO 2,6 DIIODO 1,3,5,7 TETRAMETHYL 8 (2',5' DIBROMOPHENYL) BORA 3A,4A DIAZA INDACENE; 4,4 DIFLUORO 2,6 DIIODO 1,3,5,7 TETRAMETHYL 8 (2',6' DICHLORO 4' NITROPHENYL) 4 BORA 3A,4A DIAZA INDACENE; 4,4 DIFLUORO 2,6 DIIODO 1,3,5,7 TETRAMETHYL 8 (2',6' DICHLOROPHENYL) 4 BORA 3A,4A DIAZA INDACENE; 4,4 DIFLUORO 2,6 DIIODO 1,3,5,7 TETRAMETHYL 8 (3' CYANOPHENYL) 4 BORA 3A,4A DIAZA INDACENE; 4,4 DIFLUORO 2,6 DIIODO 1,3,5,7 TETRAMETHYL 8 (3' HYDROXY 4' IODOPHENYL) 4 BORA 3A,4A DIAZA INDACENE; 4,4 DIFLUORO 2,6 DIIODO 1,3,5,7 TETRAMETHYL 8 (3' IODO 4',5' DIMETHOXYPHENYL) 4 BORA 3A,4A DIAZA INDACENE; 4,4 DIFLUORO 2,6 DIIODO 1,3,5,7 TETRAMETHYL 8 (3' METHOXYPHENYL) 4 BORA 3A,4A DIAZA INDACENE; 4,4 DIFLUORO 2,6 DIIODO 1,3,5,7 TETRAMETHYL 8 (3' PYRIDYL) 4 BORA 3A,4A DIAZA INDACENE; 4,4 DIFLUORO 2,6 DIIODO 1,3,5,7 TETRAMETHYL 8 (3',5' DIMETHOXYPHENYL) 4 BORA 3A,4A DIAZA INDACENE; 4,4 DIFLUORO 2,6 DIIODO 1,3,5,7 TETRAMETHYL 8 (4' CYANOPHENYL) 4 BORA 3A,4A DIAZA INDACENE; 4,4 DIFLUORO 2,6 DIIODO 1,3,5,7 TETRAMETHYL 8 (4' METHOXYPHENYL) 4 BORA 3A,4A DIAZA INDACENE; 4,4 DIFLUORO 2,6 DIIODO 1,3,5,7 TETRAMETHYL 8 (4' NITROPHENYL) 4 BORA 3A,4A DIAZA INDACENE; 4,4 DIFLUORO 2,6 DIIODO 1,3,5,7 TETRAMETHYL 8 (4',7' DIMETHOXYNAPHTHALENE) 4 BORA 3A,4A DIAZA INDACENE; 4,4 DIFLUORO 2,6 DIIODO 1,3,5,7 TETRAMETHYL 8 [2' (2' HYDROXYETHOXY) PHENYL] 4 BORA 3A,4A DIAZA INDACENE; 4,4 DIFLUORO 2,6 DIIODO 1,3,5,7 TETRAMETHYL 8 [2',3',4',5' TETRAFLUORO 3' [(4'' METHOXYBENZYL)SULFANYL]PHENYL] 4 BORA 3A,4A DIAZA INDACENE; 4,4 DIFLUORO 2,6 DIIODO 1,3,5,7 TETRAMETHYL 8 [4' (4' CHLOROBUTHOXY) PHENYL] 4 BORA 3A,4A DIAZA INDACENE; BORON DERIVATIVE; BORONDIPYRROMETHENE DERIVATIVE; PHOTOSENSITIZING AGENT; SINGLET OXYGEN; UNCLASSIFIED DRUG; 4,4-DIFLUORO-4-BORA-3A,4A-DIAZA-S-INDACENE;

ANTIPROLIFERATIVE ACTIVITY; ARTICLE; CELL KILLING; CELLULAR DISTRIBUTION; DRUG SYNTHESIS; FEMALE; HUMAN; HUMAN CELL; IN VITRO STUDY; LIGHT EMITTING DIODE; LIPOPHILICITY; OVARY CARCINOMA; PHOTODEGRADATION; PHOTODYNAMIC THERAPY; PRIORITY JOURNAL; QUANTITATIVE STRUCTURE ACTIVITY RELATION; QUANTUM YIELD; APOPTOSIS; CHEMISTRY; DRUG EFFECTS; ELECTROSPRAY MASS SPECTROMETRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; PHOTOCHEMOTHERAPY; PROCEDURES; SPECTROSCOPY; SYNTHESIS; TUMOR CELL LINE;

APOPTOSIS; BORON COMPOUNDS; CELL LINE, TUMOR; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; HUMANS; PHOTOCHEMOTHERAPY; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; SPECTRUM ANALYSIS;

EID: 85009402238     PISSN: 10111344     EISSN: 18732682     Source Type: Journal    
DOI: 10.1016/j.jphotobiol.2017.01.012     Document Type: Article

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