The distribution of CD44+/CD24-cancer stem cells in breast cancer and its relationship with prognostic factors

Journal of B.U.ON.

Volumn 21, Issue 5, 2016, Pages 1121-1128

  Cabuk, Devrim ^a   Yetimoglu, Eylem ^a   Simsek, Turgay ^a   Gacar, Gulcin ^a   Subasi, Cansu ^a   Canturk, Zafer ^a   Ercin, Cengiz ^a   Karaoz, Erdal ^a   Uygun, Kazim ^a  

^a KOCAELI UNIVERSITY   (Turkey)

Author keywords

Breast cancer; Cancer stem cell; CD44+ CD24V Lin CD18+; MUC1

Indexed keywords

CD16 ANTIGEN; CD18 ANTIGEN; CD19 ANTIGEN; CD2 ANTIGEN; CD24 ANTIGEN; CD3 ANTIGEN; CELL SURFACE MARKER; COMMON ACUTE LYMPHOBLASTIC LEUKEMIA ANTIGEN; CYTOKERATIN; EPIDERMAL GROWTH FACTOR RECEPTOR 2; ESTROGEN RECEPTOR; HERMES ANTIGEN; MUCIN 1; PROGESTERONE RECEPTOR; CD24 PROTEIN, HUMAN; CD44 PROTEIN, HUMAN; ERBB2 PROTEIN, HUMAN; MUC1 PROTEIN, HUMAN; TUMOR MARKER;

ADULT; AGED; ARTICLE; BREAST BIOPSY; BREAST CANCER; CANCER GRADING; CANCER PROGNOSIS; CANCER STEM CELL; CLINICAL ARTICLE; FEMALE; FLUORESCENCE ACTIVATED CELL SORTING; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; PHENOTYPE; PROTEIN EXPRESSION; BREAST NEOPLASMS; CANCER STAGING; CHEMISTRY; IMMUNOLOGY; MASTECTOMY; MIDDLE AGED; PATHOLOGY; YOUNG ADULT;

ADULT; AGED; ANTIGENS, CD24; ANTIGENS, CD44; BIOMARKERS, TUMOR; BREAST NEOPLASMS; FEMALE; HUMANS; MASTECTOMY; MIDDLE AGED; MUCIN-1; NEOPLASM STAGING; NEOPLASTIC STEM CELLS; PHENOTYPE; RECEPTOR, ERBB-2; RECEPTORS, ESTROGEN; RECEPTORS, PROGESTERONE; YOUNG ADULT;

EID: 85009352777     PISSN: 11070625     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (22)

1. Parkin DM, Bray F, Ferlay J. Global Cancer Statistics, 2002. CA Cancer J Clin 2005;55:74-108.
2. Fisher B. Laboratory and clinical research in breast cancer: An update. Int J Immunopharmacol 1999;21:79-101.
3. Cobaleda C, Crus JJ, Gonzales-Sarmiento R. Emerging Picture of Human Breast cancer as a stem cell- based disease. Stem Cell Rev 2008;4:67-79.
4. Reya T, Morrison SJ, Clarke MF, Weismman IL. Stem cell, cancer and cancer stem cell. Nature 2004;414:105-111.
5. Ailles LE, Weissman IL. Cancer stem cell in solid tumors. Curr Opin Biotechnol 2007;18:460-466.
6. Ponti D, Costa A, Zaffaroni N et al. Isolation and in vivo propagation of tumorogenic breast cancer cells with stem/progenitor cell proporties. Cancer Res 2005;65:5506-5511.
7. Al-Hajj M, Wicha MS, Benito-Hernandez A, Morrison SJ, Clarke MF. Prospective idendification of tumorigen- ic breast cancer stem cells. Proc Natl Acad Sci U S A 2003;100:3983-3988.
8. Monazzam A, Josephsson R, Blomqvist C, Carlsson J, Langstrom B, Bergstrom M. Application of the multicellular tumour spheroid model to screen PET tracers for analysis of early response of chemotherapy in breast cancer. Breast Cancer Res 2007;9:R45.
9. Ailles LE, Weissman IL. Cancer stem cell in solid tumors. Curr Opin Biotechnol 2007;18:460-466.
10. Sheridan C, Kishimoto H, Fuchs RK et al. CD44+CD24-breast cancer cells exhibit enhanced invasive properties: An early step necessary for metastasis. Breast Cancer Res 2006;8:R59.
11. Dontu G, Al-Hajj M, Abdallah WM, Clarke MF, Wicha MS. Stem cells in normal breast development and breast cancer. Cell Prolif 2003;1:59-72.
12. Honeth G, Bendahl PO, Ringner M, et al. The CD44+/CD24- phenotype is enriched in basal-like breast tumors. Breast Cancer Res 2008;10:53-65.
13. Mylona E, Giannopoulou I, Fasomytakis E et al. The clin- icopathologic and prognostic significance of CD44+/CD24-/low and CD44-/CD24+ tumor cells in invasive breast carcinomas. Hum Pathol 2008;39:1096-1102.
14. Abraham BK, Fritz P, McClellan M, Hauptvogel P, Athelogou M, Brauch H. Prevalence of CD44+CD24-/low cells in breast cancer may not be associated with clinical outcome but may favor distant metastasis. Clin Cancer Res 2005;11:1154-1159.
15. Aulmann S, Waldburger N, Penzel R, Andrulis M, Schir-macher P, Sinn HP. Reduction of CD44+/CD24- breast cancer cells by conventional cytotoxic chemotherapy. Hum Pathol 2010;41:574-581.
16. Kalirai H, Clarke RB. Human breast epithelial stem cells and their regulation. J Pathol 2006;208: 7-16.
17. Shipitsin M, Campbell LL, Argani P et al. Moleculer definition of breast tumor heterogeneity. Cancer Cell 2007;11:259- 273.
18. Liu R, Wang X, Chen GY et al. The prognostic role of a gene signature from tumorigenic breast-cancer cell. N Eng J Med 2007;356:217-226.
19. Waterworth A. Introducing the concept of breast cancer stem cells. Breast Cancer Res 2004;6:53-54.
20. Zhou L, Jiang Y, Yan T et al. The prognostic role of cancer stem cells in breast cancer: A meta-Analysis of published literatures. Breast Cancer Res 2010;122:795-801.
21. Zhang J, Wu X, Huang J. Clinical study on expression level of lymphocyte function-related antigen of breast cancer patients. Zhongguo Zhong Xi Yi Jie He Za Zhi 2000;20:110-112.
22. Leroy X, Buisine MP, Leteurtre E et al. MUC1: A key molecule of carcinogenesis? Ann Pathol 2006;26:257-266.