Anti-proliferative and apoptosis-inducing effect of theabrownin against non-small cell lung adenocarcinoma A549 cells

Frontiers in Pharmacology

Volumn 7, Issue DEC, 2016, Pages

  Wu, Feifei ^a   Zhou, Li ^b   Jin, Wangdong ^b   Yang, Weiji ^b   Wang, Ying ^b   Yan, Bo ^b   Du, Wenlin ^a   Zhang, Qiang ^a   Zhang, Lei ^c   Guo, Yonghua ^a   Zhang, Jin ^d   Shan, Letian ^b   Efferth, Thomas ^e  

^a S Evans Biosciences   (China)

^b ZHEJIANG CHINESE MEDICAL UNIVERSITY   (China)

^c ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

^d Theabio Co Ltd   (China)

^e JOHANNES GUTENBERG UNIVERSITY   (Germany)

Author keywords

A549 cells; Apoptosis; Lung cancer; P53; Theabrownin

Indexed keywords

BIM PROTEIN; CASPASE 3; CASPASE 7; CASPASE 8; CASPASE 9; DNA TOPOISOMERASE; DNA TOPOISOMERASE (ATP HYDROLYSING); GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 45; HISTONE H2AX; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PIGMENT; PROTEIN BAX; PROTEIN BCL 2; PROTEIN P53; THEABROWNIN; TRANSCRIPTION FACTOR E2F1; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; BAX GENE; BCL 2 GENE; BIM GENE; CANCER CELL; CASP 3 GENE; CASP 7 GENE; CASP 8 GENE; CASP 9 GENE; CELL PROLIFERATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA DAMAGE; DOWN REGULATION; E2F1 GENE; GADD45 GENE; GENE; GENE EXPRESSION; HUMAN; HUMAN CELL; LUNG ADENOCARCINOMA; NON SMALL CELL LUNG CANCER; P53 GENE; PROTEIN EXPRESSION; TEA; TOPO I GENE; TOPO II GENE; UPREGULATION;

EID: 85009192946     PISSN: None     EISSN: 16639812     Source Type: Journal    
DOI: 10.3389/fphar.2016.00465     Document Type: Article

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