Racial Differences in Stage IV Colorectal Cancer Survival in Younger and Older Patients

Clinical Colorectal Cancer

Volumn 16, Issue 3, 2017, Pages 178-186

  Wallace, Kristin ^a,b   DeToma, Allan ^a,b   Lewin, David N ^a,b   Sun, Shaoli ^a,b   Rockey, Don ^b   Britten, Carolyn D ^a,b   Wu, Jennifer D ^a,b   Ba, Aissatou ^a   Alberg, Anthony J ^a,b   Hill, Elizabeth G ^a,b  

^a MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^b MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

Author keywords

Colon cancer; Early onset; Metastatic; Race; Survival

Indexed keywords

ADULT; ADVANCED CANCER; AFRICAN AMERICAN; AGE; ARTICLE; ASCENDING COLON; CANCER GRADING; CANCER MORTALITY; CANCER PATIENT; CANCER PROGNOSIS; CANCER REGISTRY; CANCER STAGING; CANCER SURVIVAL; CLINICAL EVALUATION; COLORECTAL CARCINOMA; CONTROLLED STUDY; DESCENDING COLON; EUROPEAN AMERICAN; FEMALE; HIGH RISK PATIENT; HISTOPATHOLOGY; HUMAN; MAJOR CLINICAL STUDY; MALE; MEDIAN SURVIVAL TIME; MIDDLE AGED; OVERALL SURVIVAL; POPULATION RESEARCH; PREVALENCE; RACE DIFFERENCE; SURVIVAL ANALYSIS; SURVIVAL RATE; ADENOCARCINOMA; ADOLESCENT; AGED; CAUCASIAN; COLORECTAL TUMOR; HEALTH DISPARITY; KAPLAN MEIER METHOD; PROGNOSIS; PROPORTIONAL HAZARDS MODEL; VERY ELDERLY; YOUNG ADULT;

ADENOCARCINOMA; ADOLESCENT; ADULT; AFRICAN AMERICANS; AGED; AGED, 80 AND OVER; COLORECTAL NEOPLASMS; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; HEALTH STATUS DISPARITIES; HUMANS; KAPLAN-MEIER ESTIMATE; MALE; MIDDLE AGED; PROGNOSIS; PROPORTIONAL HAZARDS MODELS; SEER PROGRAM; YOUNG ADULT;

EID: 85008481729     PISSN: 15330028     EISSN: 19380674     Source Type: Journal    
DOI: 10.1016/j.clcc.2016.11.006     Document Type: Article

References (43)

1. Siegel, R., Desantis, C., Jemal, A., Colorectal cancer statistics, 2014. CA Cancer J Clin 64 (2014), 104–117.
2. Robbins, A.S., Siegel, R.L., Jemal, A., Racial disparities in stage-specific colorectal cancer mortality rates from 1985 to 2008. J Clin Oncol 30 (2012), 401–405.
3. Soneji, S., Iyer, S.S., Armstrong, K., Asch, D.A., Racial disparities in stage-specific colorectal cancer mortality: 1960-2005. Am J Public Health 100 (2010), 1912–1916.
4. Wallace, K., Hill, E.G., Lewin, D.N., et al. Racial disparities in advanced-stage colorectal cancer survival. Cancer Causes Control 24 (2013), 463–471.
5. Andaya, A.A., Enewold, L., Zahm, S.H., et al. Race and colon cancer survival in an equal-access health care system. Cancer Epidemiol Biomarkers Prev 22 (2013), 1030–1036.
6. Yoon, H.H., Shi, Q., Alberts, S.R., et al. Racial differences in BRAF/KRAS mutation rates and survival in stage III colon cancer patients. J Natl Cancer Inst, 107, 2015, 10.1093/jnci/djv186.
7. Meyerhardt, J.A., Mayer, R.J., Systemic therapy for colorectal cancer. N Engl J Med 352 (2005), 476–487.
8. Kopetz, S., Chang, G.J., Overman, M.J., et al. Improved survival in metastatic colorectal cancer is associated with adoption of hepatic resection and improved chemotherapy. J Clin Oncol 27 (2009), 3677–3683.
9. Shavers, V.L., Racial/ethnic variation in the anatomic subsite location of in situ and invasive cancers of the colon. J Natl Med Assoc 99 (2007), 733–748.
10. Thornton, J.G., Morris, A.M., Thornton, J.D., Flowers, C.R., McCashland, T.M., Racial variation in colorectal polyp and tumor location. J Natl Med Assoc 99 (2007), 723–728.
11. Lieberman, D.A., Holub, J.L., Moravec, M.D., Eisen, G.M., Peters, D., Morris, C.D., Prevalence of colon polyps detected by colonoscopy screening in asymptomatic black and white patients. JAMA 300 (2008), 1417–1422.
12. Sharma, S., O'Keefe, S.J., Environmental influences on the high mortality from colorectal cancer in African Americans. Postgrad Med J 83 (2007), 583–589.
13. Ashktorab, H., Nouraie, M., Hosseinkhah, F., Lee, E., Rotimi, C., Smoot, D., A 50-year review of colorectal cancer in African Americans: implications for prevention and treatment. Dig Dis Sci 54 (2009), 1985–1990.
14. Wallace, K., Grau, M.V., Ahnen, D., et al. The association of lifestyle and dietary factors with the risk for serrated polyps of the colorectum. Cancer Epidemiol Biomarkers Prev 18 (2009), 2310–2317.
15. Meguid, R.A., Slidell, M.B., Wolfgang, C.L., Chang, D.C., Ahuja, N., Is there a difference in survival between right- versus left-sided colon cancers?. Ann Surg Oncol 15 (2008), 2388–2394.
16. O'Connell, J.B., Maggard, M.A., Ko, C.Y., Colon cancer survival rates with the new American Joint Committee on Cancer sixth edition staging. J Natl Cancer Inst 96 (2004), 1420–1425.
17. Wray, C.M., Ziogas, A., Hinojosa, M.W., Le, H., Stamos, M.J., Zell, J.A., Tumor subsite location within the colon is prognostic for survival after colon cancer diagnosis. Dis Colon Rectum 52 (2009), 1359–1366.
18. Kalady, M.F., de Campos-Lobato, L.F., Stocchi, L., et al. Predictive factors of pathologic complete response after neoadjuvant chemoradiation for rectal cancer. Ann Surg 250 (2009), 582–589.
19. Boisen, M.K., Johansen, J.S., Dehlendorff, C., et al. Primary tumor location and bevacizumab effectiveness in patients with metastatic colorectal cancer. Ann Oncol 24 (2013), 2554–2559.
20. R: A language and environment for statistical computing, 2014, R Foundation for Statistical Computing, Vienna, Austria.
21. Rex, D.K., Johnson, D.A., Anderson, J.C., et al. American College of Gastroenterology guidelines for colorectal cancer screening 2009 [corrected]. Am J Gastroenterol 104 (2009), 739–750.
22. Qaseem, A., Denberg, T.D., Hopkins, R.H. Jr., et al. Screening for colorectal cancer: a guidance statement from the American College of Physicians. Ann Intern Med 156 (2012), 378–386.
23. Ahnen, D.J., Wade, S.W., Jones, W.F., et al. The increasing incidence of young-onset colorectal cancer: a call to action. Mayo Clin Proc 89 (2014), 216–224.
24. Wallace, K., Sterba, K.R., Gore, E., et al. Prognostic factors in relation to racial disparity in advanced colorectal cancer survival. Clin Colorectal Cancer 12 (2013), 287–293.
25. Corley, D.A., Jensen, C.D., Marks, A.R., et al. Variation of adenoma prevalence by age, sex, race, and colon location in a large population: implications for screening and quality programs. Clin Gastroenterol Hepatol 11 (2013), 172–180.
26. Lebwohl, B., Capiak, K., Neugut, A.I., Kastrinos, F., Risk of colorectal adenomas and advanced neoplasia in Hispanic, black and white patients undergoing screening colonoscopy. Aliment Pharmacol Ther 35 (2012), 1467–1473.
27. Lieberman, D.A., Williams, J.L., Holub, J.L., et al. Race, ethnicity, and sex affect risk for polyps >9 mm in average-risk individuals. Gastroenterology 147 (2014), 351–358.
28. Carethers, J.M., Murali, B., Yang, B., et al. Influence of race on microsatellite instability and CD8+ T cell infiltration in colon cancer. PLoS One, 9, 2014, e100461.
29. Xicola, R.M., Gagnon, M., Clark, J.R., et al. Excess of proximal microsatellite-stable colorectal cancer in African Americans from a multiethnic study. Clin Cancer Res 20 (2014), 4962–4970.
30. Benedix, F., Kube, R., Meyer, F., et al. Comparison of 17,641 patients with right- and left-sided colon cancer: differences in epidemiology, perioperative course, histology, and survival. Dis Colon Rectum 53 (2010), 57–64.
31. Suttie, S.A., Shaikh, I., Mullen, R., Amin, A.I., Daniel, T., Yalamarthi, S., Outcome of right- and left-sided colonic and rectal cancer following surgical resection. Colorectal Dis 13 (2011), 884–889.
32. Kim, C., Golden, S.H., Mather, K.J., et al. Racial/ethnic differences in sex hormone levels among postmenopausal women in the Diabetes Prevention Program. J Clin Endocrinol Metab 97 (2012), 4051–4060.
33. Lamon-Fava, S., Barnett, J.B., Woods, M.N., et al. Differences in serum sex hormone and plasma lipid levels in Caucasian and African-American premenopausal women. J Clin Endocrinol Metab 90 (2005), 4516–4520.
34. Randolph, J.F. Jr., Sowers, M., Gold, E.B., et al. Reproductive hormones in the early menopausal transition: relationship to ethnicity, body size, and menopausal status. J Clin Endocrinol Metab 88 (2003), 1516–1522.
35. Murphy, N., Strickler, H.D., Stanczyk, F.Z., et al. A prospective evaluation of endogenous sex hormone levels and colorectal cancer risk in postmenopausal women. J Natl Cancer Inst, 107, 2015, 10.1093/jnci/djv210.
36. Hasson, R.M., Briggs, A., Carothers, A.M., et al. Estrogen receptor alpha or beta loss in the colon of Min/+ mice promotes crypt expansion and impairs TGFbeta and HNF3beta signaling. Carcinogenesis 35 (2014), 96–102.
37. Wray, C.J., Phatak, U.R., Robinson, E.K., et al. The effect of age on race-related breast cancer survival disparities. Ann Surg Oncol 20 (2013), 2541–2547.
38. Esnaola, N.F., Gebregziabher, M., Finney, C., Ford, M.E., Underuse of surgical resection in black patients with nonmetastatic colorectal cancer: location, location, location. Ann Surg 250 (2009), 549–557.
39. Karapetis, C.S., Khambata-Ford, S., Jonker, D.J., et al. K-ras mutations and benefit from cetuximab in advanced colorectal cancer. N Engl J Med 359 (2008), 1757–1765.
40. Temple, L.K., Hsieh, L., Wong, W.D., Saltz, L., Schrag, D., Use of surgery among elderly patients with stage IV colorectal cancer. J Clin Oncol 22 (2004), 3475–3484.
41. Esnaola, N.F., Stewart, A.K., Feig, B.W., Skibber, J.M., Rodriguez-Bigas, M.A., Age-, race-, and ethnicity-related differences in the treatment of nonmetastatic rectal cancer: a patterns of care study from the national cancer data base. Ann Surg Oncol 15 (2008), 3036–3047.
42. Sanoff, H.K., Sargent, D.J., Green, E.M., McLeod, H.L., Goldberg, R.M., Racial differences in advanced colorectal cancer outcomes and pharmacogenetics: a subgroup analysis of a large randomized clinical trial. J Clin Oncol 27 (2009), 4109–4115.
43. Polite, B.N., Dignam, J.J., Olopade, O.I., Colorectal cancer and race: understanding the differences in outcomes between African Americans and whites. Med Clin North Am 89 (2005), 771–793.