메뉴 건너뛰기




Volumn 116, Issue 3, 2017, Pages 324-334

Impact of CTLA-4 blockade in conjunction with metronomic chemotherapy on preclinical breast cancer growth

Author keywords

CTLA 4; cyclophosphamide; gemcitabine; immunotherapy; metronomic chemotherapy; orthotopic

Indexed keywords

ANTINEOPLASTIC AGENT; CISPLATIN; CYCLOPHOSPHAMIDE; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4 ANTIBODY; GEMCITABINE; ALKYLATING AGENT; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; IPILIMUMAB; MONOCLONAL ANTIBODY;

EID: 85008400933     PISSN: 00070920     EISSN: 15321827     Source Type: Journal    
DOI: 10.1038/bjc.2016.429     Document Type: Article
Times cited : (35)

References (43)
  • 1
    • 84903514780 scopus 로고    scopus 로고
    • Metronomics: Towards personalized chemotherapy?
    • Andre N, Carre M, Pasquier E (2014) Metronomics: towards personalized chemotherapy? Nat Rev Clin Oncol 11: 413-431.
    • (2014) Nat Rev Clin Oncol , vol.11 , pp. 413-431
    • Andre, N.1    Carre, M.2    Pasquier, E.3
  • 2
    • 84866555540 scopus 로고    scopus 로고
    • Metronomic ceramide analogs inhibit angiogenesis in pancreatic cancer through up-regulation of caveolin-1 and thrombospondin-1 and down-regulation of cyclin D1
    • Bocci G, Fioravanti A, Orlandi P, Di Desidero T, Natale G, Fanelli G, Viacava P, Naccarato AG, Francia G, Danesi R (2012) Metronomic ceramide analogs inhibit angiogenesis in pancreatic cancer through up-regulation of caveolin-1 and thrombospondin-1 and down-regulation of cyclin D1. Neoplasia 14: 833-845.
    • (2012) Neoplasia , vol.14 , pp. 833-845
    • Bocci, G.1    Fioravanti, A.2    Orlandi, P.3    Di Desidero, T.4    Natale, G.5    Fanelli, G.6    Viacava, P.7    Naccarato, A.G.8    Francia, G.9    Danesi, R.10
  • 3
    • 0242331613 scopus 로고    scopus 로고
    • Thrombospondin 1, a mediator of the antiangiogenic effects of low-dose metronomic chemotherapy
    • Bocci G, Francia G, Man S, Lawler J, Kerbel RS (2003) Thrombospondin 1, a mediator of the antiangiogenic effects of low-dose metronomic chemotherapy. Proc Natl Acad Sci USA 100: 12917-12922.
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 12917-12922
    • Bocci, G.1    Francia, G.2    Man, S.3    Lawler, J.4    Kerbel, R.S.5
  • 4
    • 0028795554 scopus 로고
    • Molecular characterization of the in vivo alkylating agent resistant murine EMT-6 mammary carcinoma tumors
    • Chatterjee D, Liu C. J.-T., Northey D, Teicher BA (1995) Molecular characterization of the in vivo alkylating agent resistant murine EMT-6 mammary carcinoma tumors. Cancer Chemother Pharmacol 35: 423-431.
    • (1995) Cancer Chemother Pharmacol , vol.35 , pp. 423-431
    • Chatterjee, D.1    Liu, C.J.-T.2    Northey, D.3    Teicher, B.A.4
  • 5
    • 77953134540 scopus 로고    scopus 로고
    • Metronomic chemotherapy enhances antitumor effects of cancer vaccine by depleting regulatory T lymphocytes and inhibiting tumor angiogenesis
    • Chen CA, Ho CM, Chang MC, Sun WZ, Chen YL, Chiang YC, Syu MH, Hsieh CY, Cheng WF (2010) Metronomic chemotherapy enhances antitumor effects of cancer vaccine by depleting regulatory T lymphocytes and inhibiting tumor angiogenesis. Mol Ther 18: 1233-1243.
    • (2010) Mol Ther , vol.18 , pp. 1233-1243
    • Chen, C.A.1    Ho, C.M.2    Chang, M.C.3    Sun, W.Z.4    Chen, Y.L.5    Chiang, Y.C.6    Syu, M.H.7    Hsieh, C.Y.8    Cheng, W.F.9
  • 6
    • 84899111490 scopus 로고    scopus 로고
    • Preclinical analysis of resistance and cross-resistance to low-dose metronomic chemotherapy
    • Chow A, Wong A, Francia G, Man S, Kerbel RS, Emmenegger U (2014) Preclinical analysis of resistance and cross-resistance to low-dose metronomic chemotherapy. Invest New Drugs 32: 47-59.
    • (2014) Invest New Drugs , vol.32 , pp. 47-59
    • Chow, A.1    Wong, A.2    Francia, G.3    Man, S.4    Kerbel, R.S.5    Emmenegger, U.6
  • 10
    • 70350786392 scopus 로고    scopus 로고
    • Cyclophosphamide and cancer: Golden anniversary
    • Emadi A, Jones RJ, Brodsky RA (2009) Cyclophosphamide and cancer: golden anniversary. Nat Rev Clin Oncol 6: 638-647.
    • (2009) Nat Rev Clin Oncol , vol.6 , pp. 638-647
    • Emadi, A.1    Jones, R.J.2    Brodsky, R.A.3
  • 11
    • 78650991789 scopus 로고    scopus 로고
    • Tumors that acquire resistance to low-dose metronomic cyclophosphamide retain sensitivity to maximum tolerated dose cyclophosphamide
    • Emmenegger U, Francia G, Chow A, Shaked Y, Kouri A, Man S, Kerbel RS (2011) Tumors that acquire resistance to low-dose metronomic cyclophosphamide retain sensitivity to maximum tolerated dose cyclophosphamide. Neoplasia 13: 40-48.
    • (2011) Neoplasia , vol.13 , pp. 40-48
    • Emmenegger, U.1    Francia, G.2    Chow, A.3    Shaked, Y.4    Kouri, A.5    Man, S.6    Kerbel, R.S.7
  • 13
    • 79251468712 scopus 로고    scopus 로고
    • Mouse models of advanced spontaneous metastasis for experimental therapeutics
    • Francia G, Cruz-Munoz W, Man S, Xu P, Kerbel RS (2011) Mouse models of advanced spontaneous metastasis for experimental therapeutics. Nat Rev Cancer 11: 135-141.
    • (2011) Nat Rev Cancer , vol.11 , pp. 135-141
    • Francia, G.1    Cruz-Munoz, W.2    Man, S.3    Xu, P.4    Kerbel, R.S.5
  • 14
    • 55749115253 scopus 로고    scopus 로고
    • Long-term progression and therapeutic response of visceral metastatic disease non-invasively monitored in mouse urine using beta-human choriogonadotropin secreting tumor cell lines
    • Francia G, Emmenegger U, Lee CR, Shaked Y, Folkins C, Mossoba M, Medin JA, Man S, Zhu Z, Witte L, Kerbel RS (2008) Long-term progression and therapeutic response of visceral metastatic disease non-invasively monitored in mouse urine using beta-human choriogonadotropin secreting tumor cell lines. Mol Cancer Ther 7: 3452-3459.
    • (2008) Mol Cancer Ther , vol.7 , pp. 3452-3459
    • Francia, G.1    Emmenegger, U.2    Lee, C.R.3    Shaked, Y.4    Folkins, C.5    Mossoba, M.6    Medin, J.A.7    Man, S.8    Zhu, Z.9    Witte, L.10    Kerbel, R.S.11
  • 16
    • 3242741857 scopus 로고    scopus 로고
    • Gene expression analysis of tumor spheroids reveals a role for suppressed DNA mismatch repair in multicellular resistance to alkylating agents
    • Francia G, Man S, Teicher B, Grasso L, Kerbel RS (2004) Gene expression analysis of tumor spheroids reveals a role for suppressed DNA mismatch repair in multicellular resistance to alkylating agents. Mol Cell Biol 24: 6837-6849.
    • (2004) Mol Cell Biol , vol.24 , pp. 6837-6849
    • Francia, G.1    Man, S.2    Teicher, B.3    Grasso, L.4    Kerbel, R.S.5
  • 19
    • 84895904745 scopus 로고    scopus 로고
    • Mitigating the toxic effects of anticancer immunotherapy
    • Gangadhar TC, Vonderheide RH (2014) Mitigating the toxic effects of anticancer immunotherapy. Nat Rev Clin Oncol 11: 91-99.
    • (2014) Nat Rev Clin Oncol , vol.11 , pp. 91-99
    • Gangadhar, T.C.1    Vonderheide, R.H.2
  • 21
    • 84873129546 scopus 로고    scopus 로고
    • CTLA-4 blockade in tumor models: An overview of preclinical and translational research
    • Grosso JF, Jure-Kunkel MN (2013) CTLA-4 blockade in tumor models: an overview of preclinical and translational research. Cancer Immun 13: 5.
    • (2013) Cancer Immun , vol.13 , pp. 5
    • Grosso, J.F.1    Jure-Kunkel, M.N.2
  • 22
    • 84872084645 scopus 로고    scopus 로고
    • Metronomic oral topotecan prolongs survival and reduces liver metastasis in improved preclinical orthotopic and adjuvant therapy colon cancer models
    • Hackl C, Man S, Francia G, Milsom C, Xu P, Kerbel RS (2013) Metronomic oral topotecan prolongs survival and reduces liver metastasis in improved preclinical orthotopic and adjuvant therapy colon cancer models. Gut 62: 259-271.
    • (2013) Gut , vol.62 , pp. 259-271
    • Hackl, C.1    Man, S.2    Francia, G.3    Milsom, C.4    Xu, P.5    Kerbel, R.S.6
  • 25
    • 2942615257 scopus 로고    scopus 로고
    • The anti-angiogenic basis of metronomic chemotherapy
    • Kerbel RS, Kamen BA (2004) The anti-angiogenic basis of metronomic chemotherapy. Nat Rev Cancer 4: 423-436.
    • (2004) Nat Rev Cancer , vol.4 , pp. 423-436
    • Kerbel, R.S.1    Kamen, B.A.2
  • 29
    • 36249019231 scopus 로고    scopus 로고
    • Tumor lysis syndrome after treatment with gemcitabine for metastatic transitional cell carcinoma
    • Lin CJ, Lim KH, Cheng YC, Chen HH, Wu CJ (2007) Tumor lysis syndrome after treatment with gemcitabine for metastatic transitional cell carcinoma. Med Oncol 24: 455-457.
    • (2007) Med Oncol , vol.24 , pp. 455-457
    • Lin, C.J.1    Lim, K.H.2    Cheng, Y.C.3    Chen, H.H.4    Wu, C.J.5
  • 33
    • 0032404099 scopus 로고    scopus 로고
    • Realization of the therapeutic potential of CTLA-4 blockade in low-dose chemotherapytreated tumor-bearing mice
    • Mokyr MB, Kalinichenko T, Gorelik L, Bluestone JA (1998) Realization of the therapeutic potential of CTLA-4 blockade in low-dose chemotherapytreated tumor-bearing mice. Cancer Res 58: 5301-5304.
    • (1998) Cancer Res , vol.58 , pp. 5301-5304
    • Mokyr, M.B.1    Kalinichenko, T.2    Gorelik, L.3    Bluestone, J.A.4
  • 35
    • 84858766182 scopus 로고    scopus 로고
    • The blockade of immune checkpoints in cancer immunotherapy
    • Pardoll DM (2012) The blockade of immune checkpoints in cancer immunotherapy. Nat Rev Cancer 12: 252-264.
    • (2012) Nat Rev Cancer , vol.12 , pp. 252-264
    • Pardoll, D.M.1
  • 36
    • 77955172181 scopus 로고    scopus 로고
    • Metronomic chemotherapy: New rationale for new directions
    • Pasquier E, Kavallaris M, Andre N (2010) Metronomic chemotherapy: new rationale for new directions. Nat Rev Clin Oncol 7: 455-465.
    • (2010) Nat Rev Clin Oncol , vol.7 , pp. 455-465
    • Pasquier, E.1    Kavallaris, M.2    Andre, N.3
  • 37
    • 84927150740 scopus 로고    scopus 로고
    • Immune checkpoint blockade in cancer therapy
    • Postow MA, Callahan MK, Wolchok JD (2015) Immune checkpoint blockade in cancer therapy. J Clin Oncol 33: 1974-1982.
    • (2015) J Clin Oncol , vol.33 , pp. 1974-1982
    • Postow, M.A.1    Callahan, M.K.2    Wolchok, J.D.3
  • 38
    • 23844538059 scopus 로고    scopus 로고
    • Low-dose metronomic combined with intermittent bolus-dose cyclophosphamide is an effective long-term chemotherapy treatment strategy
    • Shaked Y, Emmenegger U, Francia G, Chen L, Lee CR, Man S, Paraghamian A, Ben-David Y, Kerbel RS (2005) Low-dose metronomic combined with intermittent bolus-dose cyclophosphamide is an effective long-term chemotherapy treatment strategy. Cancer Res 65: 7045-7051.
    • (2005) Cancer Res , vol.65 , pp. 7045-7051
    • Shaked, Y.1    Emmenegger, U.2    Francia, G.3    Chen, L.4    Lee, C.R.5    Man, S.6    Paraghamian, A.7    Ben-David, Y.8    Kerbel, R.S.9
  • 40
    • 78449235351 scopus 로고    scopus 로고
    • Development of a resistance-like phenotype to sorafenib by human hepatocellular carcinoma cells is reversible and can be delayed by metronomic UFT chemotherapy
    • Tang TC, Man S, Xu P, Francia G, Hashimoto K, Emmenegger U, Kerbel RS (2010) Development of a resistance-like phenotype to sorafenib by human hepatocellular carcinoma cells is reversible and can be delayed by metronomic UFT chemotherapy. Neoplasia 12: 928-940.
    • (2010) Neoplasia , vol.12 , pp. 928-940
    • Tang, T.C.1    Man, S.2    Xu, P.3    Francia, G.4    Hashimoto, K.5    Emmenegger, U.6    Kerbel, R.S.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.