Unexpected partial correction of metabolic and behavioral phenotypes of Alzheimer's APP/PSEN1 mice by gene targeting of diabetes/Alzheimer's-related Sorcs1

Acta neuropathologica communications

Volumn 4, Issue , 2016, Pages 16-

  Knight, Elysse M ^a   Ruiz, Henry H ^a   Kim, Soong Ho ^a   Harte, Jessica C ^a   Hsieh, Wilson ^a   Glabe, Charles ^a   Klein, William L ^a   Attie, Alan D ^a   Buettner, Christoph ^a   Ehrlich, Michelle E ^a   Gandy, Sam ^a  

^a VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; BRANCHED CHAIN AMINO ACID; CELL SURFACE RECEPTOR; INSULIN; LIPID; PRESENILIN 1; SORCS1 PROTEIN, HUMAN;

ADVERSE EFFECTS; ALZHEIMER DISEASE; ANIMAL; BLOOD; BODY COMPOSITION; C57BL MOUSE; COMPLICATION; DEFICIENCY; DIABETES MELLITUS, TYPE 2; DISEASE MODEL; EXPLORATORY BEHAVIOR; FEMALE; GENETICS; GLUCOSE TOLERANCE TEST; HUMAN; INSULIN RESISTANCE; LIPID DIET; MALE; MAZE TEST; MOUSE; MUTATION; PATHOPHYSIOLOGY; PHENOTYPE; PHYSIOLOGY; SEX DIFFERENCE; TRANSGENIC MOUSE;

ALZHEIMER DISEASE; AMINO ACIDS, BRANCHED-CHAIN; AMYLOID BETA-PEPTIDES; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; BODY COMPOSITION; DIABETES MELLITUS, TYPE 2; DIET, HIGH-FAT; DISEASE MODELS, ANIMAL; EXPLORATORY BEHAVIOR; FEMALE; GLUCOSE TOLERANCE TEST; HUMANS; INSULIN; INSULIN RESISTANCE; LIPIDS; MALE; MAZE LEARNING; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MUTATION; PHENOTYPE; PRESENILIN-1; RECEPTORS, CELL SURFACE; SEX FACTORS;

EID: 85008333706     PISSN: None     EISSN: 20515960     Source Type: Journal    
DOI: 10.1186/s40478-016-0282-y     Document Type: Article

References (0)