Plasmid-mediated or chromosomally mediated colistin resistance in Klebsiella pneumoniae?

The Lancet Infectious Diseases

Volumn 17, Issue 1, 2017, Pages 26-27

  Antonelli, Alberto ^a   D'Andrea, Marco Maria ^a,b   Giani, Tommaso ^b   Rossolini, Gian Maria ^a,b,c,d  

^a UNIVERSITY OF FLORENCE   (Italy)

^b UNIVERSITY OF SIENA   (Italy)

^c CAREGGI UNIVERSITY HOSPITAL   (Italy)

^d IRCCS FONDAZIONE DON CARLO GNOCCHI   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

COLISTIN; SPACER DNA;

ANTIBIOTIC RESISTANCE; BACTERIAL CHROMOSOME; BLOOD SAMPLING; CHROMOSOME; GENE INSERTION SEQUENCE; GENOME; GENOME ANALYSIS; HUMAN; KLEBSIELLA PNEUMONIAE; LETTER; MISSENSE MUTATION; PHENOTYPE; PRIORITY JOURNAL; PROMOTER REGION; SINGLE NUCLEOTIDE POLYMORPHISM;

EID: 85008199373     PISSN: 14733099     EISSN: 14744457     Source Type: Journal    
DOI: 10.1016/S1473-3099(16)30552-7     Document Type: Letter

References (5)

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2. 2 Cannatelli, A, Di Pilato, V, Giani, T, Arena, F, Ambretti, S, Gaibani, P, et al. In vivo evolution to colistin resistance by PmrB sensor kinase mutation in KPC-producing Klebsiella pneumoniae is associated with low-dosage colistin treatment. Antimicrob Agents Chemother 58 (2014), 4399–4403.
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5. 5 Cannatelli, A, D'Andrea, MM, Giani, T, et al. In vivo emergence of colistin resistance in Klebsiella pneumoniae producing KPC-type carbapenemases mediated by insertional inactivation of the PhoQ/PhoP mgrB regulator. Antimicrob Agents Chemother 57 (2013), 5521–5526.