Everyday unfair treatment and multisystem biological dysregulation in African American adults

Cultural Diversity and Ethnic Minority Psychology

Volumn 23, Issue 1, 2017, Pages 27-35

  Ong, Anthony D ^a,b   Williams, David R ^c   Nwizu, Ujuonu ^a   Gruenewald, Tara L ^d  

^a Department of Obstetrics Gynecology   (United States)

^b WEILL CORNELL MEDICAL COLLEGE   (United States)

^c HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^d UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

Allostatic load; Biological processes; Chronic discrimination; Unfair treatment

Indexed keywords

GLUCOSE; LIPID;

ADRENERGIC SYSTEM; ADULT; AFRICAN AMERICAN; ALCOHOL CONSUMPTION; ARTICLE; CARDIOVASCULAR FUNCTION; CHOLINERGIC SYSTEM; DEMOGRAPHY; DEPRESSION; DRUG USE; FEMALE; GLUCOSE BLOOD LEVEL; HEALTH STATUS; HIGH RISK POPULATION; HUMAN; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; INFLAMMATION; LIPID BLOOD LEVEL; LONG TERM EXPOSURE; MALE; NORMAL HUMAN; PERCEPTION; PERSONAL EXPERIENCE; PHYSIOLOGICAL STRESS; QUESTIONNAIRE; RACISM; SMOKING; SOCIAL STATUS; AGED; ALLOSTASIS; HYPOPHYSIS ADRENAL SYSTEM; HYPOTHALAMUS HYPOPHYSIS SYSTEM; MIDDLE AGED; PREJUDICE; PSYCHOLOGY; SOCIAL DISCRIMINATION; VERY ELDERLY;

ADULT; AFRICAN AMERICANS; AGED; AGED, 80 AND OVER; ALLOSTASIS; FEMALE; HUMANS; HYPOTHALAMO-HYPOPHYSEAL SYSTEM; MALE; MIDDLE AGED; PITUITARY-ADRENAL SYSTEM; PREJUDICE; SOCIAL DISCRIMINATION; SURVEYS AND QUESTIONNAIRES;

EID: 85008166441     PISSN: 10999809     EISSN: 19390106     Source Type: Journal    
DOI: 10.1037/cdp0000087     Document Type: Article

References (64)

1. Barnes, L. L., Mendes De Leon, C. F., Wilson, R. S., Bienias, J. L., Bennett, D. A., & Evans, D. A. (2004). Racial differences in perceived discrimination in a community population of older blacks and whites. Journal of Aging and Health, 16, 315-337. http://dx.doi.org/10.1177/ 0898264304264202
2. Beatty, D. L., & Matthews, K. A. (2009). Unfair treatment and trait anger in relation to nighttime ambulatory blood pressure in African American and White adolescents. Psychosomatic Medicine, 71, 813-820. http:// dx.doi.org/10.1097/PSY.0b013e3181b3b6f8
3. Blendon, R. J., Aiken, L. H., Freeman, H. E., & Corey, C. R. (1989). Access to medical care for black and white Americans. A matter of continuing concern. Journal of the American Medical Association, 261, 278-281. http://dx.doi.org/10.1001/jama.1989.03420020132045
4. Brim, O. G., Ryff, C. D., & Kessler, R. C. (Eds.). (2004). How healthy are we? A national study of well-being at midlife. Chicago, IL: University of Chicago Press.
5. Brody, G. H., Lei, M. K., Chae, D. H., Yu, T., Kogan, S. M., & Beach, S. R. H. (2014). Perceived discrimination among African American adolescents and allostatic load: A longitudinal analysis with buffering effects. Child Development, 85, 989-1002. http://dx.doi.org/10.1111/ cdev.12213
6. Brown, T. N., Williams, D. R., Jackson, J. S., Neighbors, H. W., Torres, M. M., Sellers, S. L., & Brown, K. T. (2000). "Being black and feeling blue": The mental health consequences of racial discrimination. Race and Society, 2, 117-131. http://dx.doi.org/10.1016/S1090-9524(00) 00010-3
7. Clark, L. A., & Watson, D. (1991). Tripartite model of anxiety and depression: Psychometric evidence and taxonomic implications. Journal of Abnormal Psychology, 100, 316-336. http://dx.doi.org/10.1037/0021-843X.100.3.316
8. Cohen, J., West, S. G., & Aiken, L. S. (2003). Applied multiple regression/ correlation analysis for the behavioral sciences (3rd ed.). Mahwah, NJ: Erlbaum, Publishers.
9. Crowley, O. V., McKinley, P. S., Burg, M. M., Schwartz, J. E., Ryff, C. D., Weinstein, M., Sloan, R. P. (2011). The interactive effect of change in perceived stress and trait anxiety on vagal recovery from cognitive challenge. International Journal of Psychophysiology, 82, 225-232. http://dx.doi.org/10.1016/j.ijpsycho.2011.09.002
10. DeLongis, A., Coyne, J. C., Dakof, G., Folkman, S., & Lazarus, R. S. (1982). Relationship of daily hassles, uplifts, and major life events to health status. Health Psychology, 1, 119-136. http://dx.doi.org/10.1037/ 0278-6133.1.2.119
11. De Vogli, R., Ferrie, J. E., Chandola, T., Kivimäki, M., & Marmot, M. G. (2007). Unfairness and health: Evidence from the Whitehall II Study. Journal of Epidemiology and Community Health, 61, 513-518. http:// dx.doi.org/10.1136/jech.2006.052563
12. Dienberg Love, G., Seeman, T. E., Weinstein, M., & Ryff, C. D. (2010). Bioindicators in the MIDUS national study: Protocol, measures, sample, and comparative context. Journal of Aging and Health, 22, 1059-1080. http://dx.doi.org/10.1177/0898264310374355
13. Forman, T. A., Williams, D. R., & Jackson, J. S. (1997). Race, place, and discrimination. Perspectives on Social Problems, 9, 231-261.
14. Friedman, E. M., Williams, D. R., Singer, B. H., & Ryff, C. D. (2009). Chronic discrimination predicts higher circulating levels of E-selectin in a national sample: The MIDUS study. Brain, Behavior, and Immunity, 23, 684-692. http://dx.doi.org/10.1016/j.bbi.2009.01.002
15. Fuller-Rowell, T. E., Doan, S. N., & Eccles, J. S. (2012). Differential effects of perceived discrimination on the diurnal cortisol rhythm of African Americans and Whites. Psychoneuroendocrinology, 37, 107-118. http://dx.doi.org/10.1016/j.psyneuen.2011.05.011
16. Geronimus, A. T., Hicken, M., Keene, D., & Bound, J. (2006). "Weathering" and age patterns of allostatic load scores among blacks and whites in the United States. American Journal of Public Health, 96, 826-833. http://dx.doi.org/10.2105/AJPH.2004.060749
17. Graham, J. W. (2009). Missing data analysis: Making it work in the real world. Annual Review of Psychology, 60, 549-576. http://dx.doi.org/10.1146/annurev.psych.58.110405.085530
18. Gruenewald, T. L., Karlamangla, A. S., Hu, P., Stein-Merkin, S., Crandall, C., Koretz, B., & Seeman, T. E. (2012). History of socioeconomic disadvantage and allostatic load in later life. Social Science & Medicine, 74, 75-83. http://dx.doi.org/10.1016/j.socscimed.2011.09.037
19. Harel, O. (2009). The estimation of R2 and adjusted R2 in incomplete data sets using multiple imputation. Journal of Applied Statistics, 36, 1109-1118. http://dx.doi.org/10.1080/02664760802553000
20. House, J. S., Lantz, P. M., & Herd, P. (2005). Continuity and change in the social stratification of aging and health over the life course: Evidence from a nationally representative longitudinal study from 1986 to 2001/ 2002 (Americans' Changing Lives Study). The Journals of Gerontology Series B, Psychological Sciences and Social Sciences, 60, 15-26. http:// dx.doi.org/10.1093/geronb/60.Special_Issue_2.S15
21. Hunte, H. E. (2011). Association between perceived interpersonal everyday discrimination and waist circumference over a 9-year period in the Midlife Development in the United States cohort study. American Journal of Epidemiology and Community Health, 173, 1232-1239. http://dx.doi.org/10.1093/aje/kwq463
22. Kanner, A. D., Coyne, J. C., Schaefer, C., & Lazarus, R. S. (1981). Comparison of two modes of stress measurement: Daily hassles and uplifts versus major life events. Journal of Behavioral Medicine, 4, 1-39. http://dx.doi.org/10.1007/BF00844845
23. Karlamangla, A. S., Singer, B. H., McEwen, B. S., Rowe, J. W., & Seeman, T. E. (2002). Allostatic load as a predictor of functional decline. Mac-Arthur studies of successful aging. Journal of Clinical Epidemiology, 55, 696-710. http://dx.doi.org/10.1016/S0895-4356(02)00399-2
24. Karlamangla, A. S., Singer, B. H., & Seeman, T. E. (2006). Reduction in allostatic load in older adults is associated with lower all-cause mortality risk: MacArthur studies of successful aging. Psychosomatic Medicine, 68, 500-507. http://dx.doi.org/10.1097/01.psy.0000221270.93985.82
25. Kessler, R. C., Mickelson, K. D., & Williams, D. R. (1999). The prevalence, distribution, and mental health correlates of perceived discrimination in the United States. Journal of Health and Social Behavior, 40, 208-230. http://dx.doi.org/10.2307/2676349
26. Krieger, N. (1990). Racial and gender discrimination: Risk factors for high blood pressure? Social Science & Medicine, 30, 1273-1281. http://dx.doi.org/10.1016/0277-9536(90)90307-E
27. Krieger, N. (1999). Embodying inequality: A review of concepts, measures, and methods for studying health consequences of discrimination. International Journal of Health Services, 29, 295-352. http://dx.doi.org/ 10.2190/M11W-VWXE-KQM9-G97Q
28. Lewis, T. T., Aiello, A. E., Leurgans, S., Kelly, J., & Barnes, L. L. (2010). Self-reported experiences of everyday discrimination are associated with elevated C-reactive protein levels in older African-American adults. Brain, Behavior, and Immunity, 24, 438-443. http://dx.doi.org/10.1016/ j.bbi.2009.11.011
29. Lewis, T. T., Cogburn, C. D., & Williams, D. R. (2015). Self-reported experiences of discrimination and health: Scientific advances, ongoing controversies, and emerging issues. Annual Review of Clinical Psychology, 11, 407-440. http://dx.doi.org/10.1146/annurev-clinpsy-032814-112728
30. Lewis, T. T., Everson-Rose, S. A., Powell, L. H., Matthews, K. A., Brown, C., Karavolos, K., Wesley, D. (2006). Chronic exposure to everyday discrimination and coronary artery calcification in African-American women: The SWAN Heart Study. Psychosomatic Medicine, 68, 362-368. http://dx.doi.org/10.1097/01.psy.0000221360.94700.16
31. Lewis, T. T., Troxel, W. M., Kravitz, H. M., Bromberger, J. T., Matthews, K. A., & Hall, M. H. (2013). Chronic exposure to everyday discrimination and sleep in a multiethnic sample of middle-aged women. Health Psychology, 32, 810-819. http://dx.doi.org/10.1037/a0029938
32. Lewis, T. T., Yang, F. M., Jacobs, E. A., & Fitchett, G. (2012). Racial/ ethnic differences in responses to the everyday discrimination scale: A differential item functioning analysis. American Journal of Epidemiology, 175, 391-401. http://dx.doi.org/10.1093/aje/kwr287
33. Lynch, J., & Smith, G. D. (2005). A life course approach to chronic disease epidemiology. Annual Review of Public Health, 26, 1-35. http://dx.doi.org/10.1146/annurev.publhealth.26.021304.144505
34. Mays, V. M., & Cochran, S. D. (2001). Mental health correlates of perceived discrimination among lesbian, gay, and bisexual adults in the United States. American Journal of Public Health, 91, 1869-1876. http://dx.doi.org/10.2105/AJPH.91.11.1869
35. Mays, V. M., Cochran, S. D., & Barnes, N. W. (2007). Race, race-based discrimination, and health outcomes among African Americans. Annual Review of Psychology, 58, 201-225. http://dx.doi.org/10.1146/annurev.psych.57.102904.190212
36. McEwen, B. S. (2000). Allostasis and allostatic load: Implications for neuropsychopharmacology. Neuropsychopharmacology, 22, 108-124. http://dx.doi.org/10.1016/S0893-133X(99)00129-3
37. McEwen, B. S. (2003). Mood disorders and allostatic load. Biological Psychiatry, 54, 200-207. http://dx.doi.org/10.1016/S0006-3223 (03)00177-X
38. McEwen, B. S., & Seeman, T. (1999). Protective and damaging effects of mediators of stress. Elaborating and testing the concepts of allostasis and allostatic load. Annals of the New York Academy of Sciences, 896, 30-47. http://dx.doi.org/10.1111/j.1749-6632.1999.tb08103.x
39. McEwen, B. S., & Stellar, E. (1993). Stress and the individual. Mechanisms leading to disease. Archives of Internal Medicine, 153, 2093-2101. http://dx.doi.org/10.1001/archinte.1993.00410180039004
40. Ong, A. D., Fuller-Rowell, T., & Burrow, A. L. (2009). Racial discrimination and the stress process. Journal of Personality and Social Psychology, 96, 1259-1271. http://dx.doi.org/10.1037/a0015335
41. Pascoe, E. A., & Smart Richman, L. (2009). Perceived discrimination and health: A meta-analytic review. Psychological Bulletin, 135, 531-554. http://dx.doi.org/10.1037/a0016059
42. Pieterse, A. L., Todd, N. R., Neville, H. A., & Carter, R. T. (2012). Perceived racism and mental health among Black American adults: A meta-analytic review. Journal of Counseling Psychology, 59, 1-9. http:// dx.doi.org/10.1037/a0026208
43. Roberts, C. B., Vines, A. I., Kaufman, J. S., & James, S. A. (2008). Cross-sectional association between perceived discrimination and hypertension in African-American men and women: The Pitt County Study. American Journal of Epidemiology, 167, 624-632. http://dx.doi.org/10.1093/aje/kwm334
44. Royston, P. (2005). Multiple imputation of missing values: Update. The Stata Journal, 5, 188-201.
45. Rubin, D. B. (1987). Multiple imputation for nonresponse in surveys. New York, NY: Wiley. http://dx.doi.org/10.1002/9780470316696
46. Ryff, C. D., Almeida, D. M., Ayanian, J. S., Carr, D. S., Cleary, P. D., Coe, C., & Williams, D. R. (2008a). Field report-Midlife development in the United States (MIDUS II): Milwaukee African American sample, 2005-2006. Ann Arbor, MI: Inter-university Consortium for Political and Social Research.
47. Ryff, C. D., Almeida, D. M., Ayanian, J. S., Carr, D. S., Cleary, P. D., Coe, C., & Williams, D. R. (2008b). National Survey of Midlife Development in the United States (MIDUS II), 2004-2006. ICPSR04652-v6. Ann Arbor, MI: Inter-University Consortium for Political and Social Research.
48. Schmitt, M. T., Branscombe, N. R., Postmes, T., & Garcia, A. (2014). The consequences of perceived discrimination for psychological well-being: A meta-analytic review. Psychological Bulletin, 140, 921-948. http://dx.doi.org/10.1037/a0035754
49. Schulz, A., Israel, B., Williams, D., Parker, E., Becker, A., & James, S. (2000). Social inequalities, stressors and self reported health status among African American and white women in the Detroit metropolitan area. Social Science & Medicine, 51, 1639-1653. http://dx.doi.org/10.1016/S0277-9536(00)00084-8
50. Seeman, T. E., Crimmins, E., Huang, M. H., Singer, B., Bucur, A., Gruenewald, T., Reuben, D. B. (2004). Cumulative biological risk and socio-economic differences in mortality: MacArthur studies of successful aging. Social Science & Medicine, 58, 1985-1997. http://dx.doi.org/10.1016/S0277-9536(03)00402-7
51. Seeman, T., Epel, E., Gruenewald, T., Karlamangla, A., & McEwen, B. S. (2010). Socio-economic differentials in peripheral biology: Cumulative allostatic load. Annals of the New York Academy of Sciences, 1186, 223-239. http://dx.doi.org/10.1111/j.1749-6632.2009.05341.x
52. Seeman, T. E., McEwen, B. S., Rowe, J. W., & Singer, B. H. (2001). Allostatic load as a marker of cumulative biological risk: MacArthur studies of successful aging. Proceedings of the National Academy of Sciences of the United States of America, 98, 4770-4775. http://dx.doi.org/10.1073/pnas.081072698
53. Seeman, T. E., Singer, B. H., Rowe, J. W., Horwitz, R. I., & McEwen, B. S. (1997). Price of adaptation-Allostatic load and its health consequences. MacArthur studies of successful aging. Archives of Internal Medicine, 157, 2259-2268. http://dx.doi.org/10.1001/ archinte.1997.00440400111013
54. Seeman, T. E., Singer, B. H., Ryff, C. D., Dienberg Love, G., & Levy-Storms, L. (2002). Social relationships, gender, and allostatic load across two age cohorts. Psychosomatic Medicine, 64, 395-406. http://dx.doi.org/10.1097/00006842-200205000-00004
55. Segerstrom, S. C., & Miller, G. E. (2004). Psychological stress and the human immune system: A meta-analytic study of 30 years of inquiry. Psychological Bulletin, 130, 601-630.
56. Selzer, M. L. (1971). The Michigan alcoholism screening test: The quest for a new diagnostic instrument. The American Journal of Psychiatry, 127, 1653-1658. http://dx.doi.org/10.1176/ajp.127.12.1653
57. Smart Richman, L., Pek, J., Pascoe, E., & Bauer, D. J. (2010). The effects of perceived discrimination on ambulatory blood pressure and affective responses to interpersonal stress modeled over 24 hours. Health Psychology, 29, 403-411. http://dx.doi.org/10.1037/a0019045
58. Soto, J. A., Dawson-Andoh, N. A., & BeLue, R. (2011). The relationship between perceived discrimination and generalized anxiety disorder among African Americans, Afro Caribbeans, and non-Hispanic Whites. Journal of Anxiety Disorders, 25, 258-265. http://dx.doi.org/10.1016/j.janxdis.2010.09.011
59. Troxel, W. M., Matthews, K. A., Bromberger, J. T., & Sutton-Tyrrell, K. (2003). Chronic stress burden, discrimination, and subclinical carotid artery disease in African American and Caucasian women. Health Psychology, 22, 300-309. http://dx.doi.org/10.1037/0278-6133.22.3.300
60. Upchurch, D. M., Stein, J., Greendale, G. A., Chyu, L., Tseng, C.-H., Huang, M.-H., Seeman, T. (2015). A longitudinal investigation of race, socioeconomic status, and psychological mediators of allostatic load in midlife women: Findings from the study of women's health across the nation. Psychosomatic Medicine, 77, 402-412. http://dx.doi.org/10.1097/PSY.0000000000000175
61. Williams, D. R., & Mohammed, S. A. (2009). Discrimination and racial disparities in health: Evidence and needed research. Journal of Behavioral Medicine, 32, 20-47. http://dx.doi.org/10.1007/s10865-008-9185-0
62. Williams, D. R., & Rucker, T. D. (2000). Understanding and addressing racial disparities in health care. Health Care Financing Review, 21, 75-90.
63. Williams, D. R., Yu, Y., Jackson, J. S., & Anderson, N. B. (1997). Racial differences in physical and mental health: Socioeconomic status, stress, and discrimination. Journal of Health Psychology, 2, 335-351. http://dx.doi.org/10.1177/135910539700200305
64. Yancik, R., Ershler, W., Satariano, W., Hazzard, W., Cohen, H. J., & Ferrucci, L. (2007). Report of the national institute on aging task force on comorbidity. The Journals of Gerontology Series A, Biological Sciences and Medical Sciences, 62, 275-280. http://dx.doi.org/10.1093/ gerona/62.3.275